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Medical students’perceptions about the added educational value of student-run HIV/AIDS educational campaigns in the Dominican Republic

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Global Health Research and Policy 2016年第1期1卷 101-105页

作者： Helena j.Chapman jessica Bottentuit-Rocha Department of Environmental and Global Health College of Public Health and Health ProfessionsUniversity of FloridaGainesvilleFLUSA School of Medicine Universidad Nacional Pedro Henríquez UreñaSanto DomingoDominican Republic

Objective:This purpose of this report was to examine the perceptions of medical students about the strengths,limitations,and recommendations for improvement of the first known student-run HIV/AIDS educational campaigns in the Dominican Republic(DR),as they relate to the added value applied to their educational ***:A retrospective review was conducted on evaluation reports completed by five medical students who coordinated the implementation of three annual HIV/AIDS educational campaigns in five DR communities,between 2012 and *** analysis was used to identify emerging themes related to perceived strengths,limitations,and recommendations for improvement and develop an acronym related to program strengths as value added to medical ***:Students highlighted that program strengths were the use of social media technology to facilitate communication and culture-based creativity to capture the attention of target audiences;and limitations were inadequate financial support and HIV-related cultural stigma,due to lack of disease knowledge and awareness or perceived contrasts between the federal system and faith-based *** for program improvement,such as comprehensive event preparation and knowing the target audience,were described as key to maximizing the delivery of health ***:Our results highlighted that medical students gained expertise in the effective use of social media technology,culture-based creativity,and team synergy to disseminate HIV/AIDS health information across five DR *** participated in these extracurricular community health campaigns,strengthening skills in communication,health advocacy,and leadership for their medical *** served as human resources for health and can pave the way as future clinicians and indispensable health educators in local and national health collaborations.

关键词： Acquired immunodeficiency syndrome Dominican Republic Health education Medical education

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Sleep and stress in the acute phase of concussion in youth

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Sports Medicine and Health Science 2020年第2期2卷 109-114页

作者： Arthur Maerlender Caitlin Masterson jessica L.Calvi Todd Caze Ross Mathiasen Dennis Molfese Center for Brain Biologyand BehaviorEast StadiumUniversity of Nebraska-LincolnNEUSA Nebraska Medicine S 42nd&Emile StOmahaNEUSA Salivary Bioscience Laboratory East StadiumUniversity of Nebraska-LincolnNEUSA University of Nebraska Medical School S 42nd&Emile StOmahaNEUSA

This study sought to address the complex interplay between both biological and psychological perceptions of stress and sleep in the acute stages following a mild traumatic brain injury.A secondary goal was to identify potential targets for *** acutely injured youth(mean age 12 years)were studied at home with overnight actigraphy,salivary cortisol and melatonin assays,and subjective ratings of stress and fatigue(injured group).Nine matched control youth also were assessed(control group).Results suggested longer sleep latencies(time to fall asleep)and higher levels of fatigue in the injured group exist(p=0.025 and p=0.004,respectively).In the injured group,stress and sleep onset were significantly related with most subjects meeting criteria for Acute Stress *** levels were lower at bedtime in the injured *** samples were collected via passive drool at three time points:~1 h before bed(“bedtime”or T1),immediately upon waking(time 2:T2),and 30 min post-waking(time 3:T3).Overnight increases in cortisol(T1 to T2)were greater for the injured group;however,post-sleep changes in cortisol(T2 to T3)were reversed with control concentrations *** findings are unique in using actigraphy and salivary hormone levels in an acutely injured youth while in their *** differences in sleep latency and the presence of injury-related stress point to potential treatment targets in acute concussion.

关键词： Sleep Mild traumatic brain injury Fatigue Actigraphy Youth Salivary hormones Stress Concussion

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jia Pingwa As I See Him

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东吴学术 2016年第1期 50-52页

作者： Mo Yan jessica Yeung

Pingwa and I are of similar *** also share similar *** both grew up in the village;we both experienced the same process of change in the 1950s,‘60s and‘70s and in the Reform era that *** have seen the same turbulence and turmoil in our society and the same distrust and animosity between human *** each of our perspectives and via the

关键词： jia Pingwa As I See Him As

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Multi-target prediction of wheat flour quality parameters with near infrared spectroscopy

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Information Processing in Agriculture 2020年第2期7卷 342-354页

作者： Sylvio Barbon junior Saulo Martielo Mastelini Ana Paula ACBarbon Douglas Fernandes Barbin Rosalba Calvini jessica Fernandes Lopes Alessandro Ulrici Computer Science Department Londrina State University(UEL)Londrina 86057-970Brazil Animal Science Department Londrina State University(UEL)Londrina 86057-970Brazil Department of Food Engineering Campinas State University(UNICAMP)Campinas 13083-862Brazil Department of Life Science University of Modena and Reggio Emilia(UNIMORE)42122 Reggio EmiliaItaly

Near Infrared(NIR)spectroscopy is an analytical technology widely used for the nondestructive characterisation of organic samples,considering both qualitative and quantitative *** the present study,the combination of Multi-target(MT)prediction approaches and Machine Learning algorithms has been evaluated as an effective strategy to improve prediction performances of NIR data from wheat flour *** different Multi-target approaches have been tested:Multi-target Regressor Stacking(MTRS),Ensemble of Regressor Chains(ERC)and Deep Structure for Tracking Asynchronous Regressor Stack(DSTARS).Each one of these techniques has been tested with different regression methods:Support Vector Machine(SVM),Random Forest(RF)and Linear Regression(LR),on a dataset composed of NIR spectra of bread wheat flours for the prediction of qualityrelated *** combining all MT techniques and predictors,we obtained an improvement up to 7%in predictive performance,compared with the corresponding Single-target(ST)*** results support the potential advantage of MT techniques over ST techniques for analysing NIR spectra.

关键词： Random forest Support Vector Machine Near-infrared spectroscopy Machine learning MTRS DSTARS Partial Least Squares ERC

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A peptide-based assay discriminates individual antibody response to SARS-CoV-2

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Genes & Diseases 2022年第1期9卷 275-281页

作者： Immacolata Polvere Serena Voccola Gaetano Cardinale Maurizio Fumi Francesca Aquila Alfredina Parrell jessica Raffaella Madera Romania Stilo Pasquale Vito Tiziana Zotti Dipartimento di Scienze e Tecnologie Universitàdegli Studi del SannioVia dei Mulini snc82100 BeneventoItaly Genus Biotech Universitàdegli Studi del SannioVia Appia s.n.c.82030 Apollosa(BN)Italy Azienda Ospedaliera San Pio Via Pacevecchia5382100 Benevento(BN)Italy

SARS-CoV-2 virus is responsible for the current worldwide coronavirus disease 2019 (COVID-19) pandemic, infecting millions of people and causing hundreds of thousands of deaths. Understanding the antibody response to SARS-CoV-2 is crucial for the development of vaccines, therapeutics and public health interventions. However, lack of consistency in methods used to monitor antibody response to SARS-CoV-2 leaves some uncertainty in our fine understanding of the human antibody response mounted following SARS-CoV-2 infection. We developed a peptide-based enzyme-linked immunosorbent assay (ELISA) by selecting 7 synthetic peptides from the spike, membrane, and nucleocapsid protein sequences of SARS-CoV-2, which effectively detects the antibody response mounted by all COVID-19 convalescent tested. Strikingly, the assay shows a profound difference in antibody response among individual subjects, which may have a significant impact on disease severity. Together, our results define an efficient and specific serological assay to consistently measure the antibody response following SARS-CoV-2 infection, as well as help the design of vaccine and therapeuticals for prevention and treatment of COVID-19.

关键词： Antibodies Assay COVID-19 ELISA Peptides SARS-Cov-2

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Presence of blaOXA-48-carrying IncF plasmid in an Escherichia fergusonii strain isolated from a sugarcane soil

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Pedosphere 2020年第2期30卷 293-294页

作者： jessica Aparecida Silva MORETTO joao Pedro Rueda FURLAN Vania Santos BRAZ Tamires Aparecida BITENCOURT Eliana Guedes STEHLING Departamento de Analises Clinicas Toxicologicas e BromatologicasFaculdade de Ciencias Farmaceuticas de Ribeirao PretoUniversidade de Sao PauloRibeirao Preto SP 14040-903(Brazil Departamento de Genetica Faculdade de Medicina de Ribeirao PretoUniversidade de Sao PauloRibeirao Preto SP 14040-903(Brazil

Dear Editor,A large number of antimicrobial agents used for the treatment of humans and animals reach water sources and agricultural soils in different ways,including animal ***,antimicrobial-resistant bacteria,carrying important antimicrobial resistance genes(ARGs),circulate between humans,animals,and the environment,giving attention to the concept of One Health(Topp,2017;Tiedje et al.,2019).

关键词： soil soils sugarcane

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A Robust and Economical Underwater Stereo Video System to Observe Antarctic Krill (Euphausia superba)

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Open journal of Marine Science 2013年第3期3卷 148-153页

作者： Tom B. Letessier So Kawaguchi Rob King jessica j. Meeuwig Robert Harcourt Martin j. Cox Australian Antarctic Division Channel Highway Kingston Australia Centre for Marine Futures Oceans Institute The University of Western Australia Department of Biological Sciences Faculty of Science Macquarie University Sydney Australia

In situ characterization of krill morphometry, behaviour and orientation is not yet routinely feasible, yet is critical to understanding swarm characteristics. A first step is to measure individual and aggregation behaviour. We report on successful use of a robust, low-cost underwater stereo video camera system to observe live Antarctic krill (Euphausia superba) in aquaria. The application of photogrammetry techniques allows animal length, orientation and three-dimensional position to be calculated from stereo video camera observations. Initially, we tested the efficacy of the stereo system by observing synthetic targets of known length and orientation to obtain estimates of measurement error. We found that on average the stereo camera system underestimated length by 0.6 mm and vertical tilt angle by +0.34°(head up), but that photogrammetric measurements of 100 randomly selected krill lengths were not significantly different from measurements of 100 randomly caught krill measured physically. During our investigation, we analysed three krill behavioural metrics: swimming speed, tortuosity, and vertical orientation under three behavioural states (undisturbed, feeding, and escape). We found that swim speed and tortuosity significantly increased when animals were feeding or exhibiting an escape response, but vertical orientation was not significantly different across states. Our investigation demonstrates that low-cost stereo video cameras can produce precise measurements that can be used for monitoring krill behaviour and population structure.

关键词： Behaviour Orientation Size Aquaria Photogrammetry GoPro

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Chitosan coatings with distinct innate immune bioactivities differentially stimulate angiogenesis,osteogenesis and chondrogenesis in poly-caprolactone scaffolds with controlled interconnecting pore size

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Bioactive Materials 2022年第4期7卷 430-442页

作者： Caroline D.Hoemann javier Rodríguez Gonzalez jessica Guzman-Morales Gaoping Chen Ebrahim jalali Dil Basil D.Favis Department of Chemical Engineering Polytechnique MontrealQCCanada Department of Bioengineering George Mason University VAUSA Centre de Recherche sur les Systemes Polymeres et Composites a Haute Performance(CREPEC) Canada

This study tested whether osseous integration into poly(ε-caprolactone)(PCL)bioplastic scaffolds with fully-interconnecting 155±8μm pores is enhanced by an adhesive,non-inflammatory 99% degree of deacetylation(DDA)chitosan coating(99-PCL),or further incorporation of pro-inflammatory 83% DDA chitosan microparticles(83-99-PCL)to accelerate *** Zealand White rabbit osteochondral knee defects were press-fit with PCL,99-PCL,83-99-PCL,or allowed to bleed(drill-only).Between day 1 and 6 weeks of repair,drill-only defects repaired by endochondral ossification,with an 8-fold higher bone volume fraction(BVF)versus initial defects,compared to a 2-fold(99-PCL),1.1-fold(PCL),or 0.4-fold(83-99-PCL)change in *** innate immune cells swarmed to 83-99-PCL,elicited angiogenesis throughout the pores and induced slight bone *** and 99-PCL pores were variably filled with cartilage or avascular mesenchyme near the bone plate,or angiogenic mesenchyme into which repairing trabecular bone infiltrated up to 1 mm *** repair cartilage covered the 99-PCL scaffold(65%)than PCL(18%)or 83-99-PCL(0%)(p<0.005).We report the novel finding that non-inflammatory chitosan coatings promoted cartilage infiltration into and over a bioplastic scaffold,and were compatible with trabecular bone *** study also revealed that in vitro osteogenesis assays have limited ability to predict osseous integration into porous scaffolds,because(1)in vivo,woven bone integrates from the leading edge of regenerating trabecular bone and not from mesenchymal cells adhering to scaffold surfaces,and(2)bioactive coatings that attract inflammatory cells induce bone resorption.

关键词： Bone tissue engineering Cartilage tissue engineering Hematoma Chitosan Angiogenesis Osteogenesis Inflammation

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Understanding the role of transition metal single-atom electronic structure in oxysulfur radical-mediated oxidative degradation

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Environmental Science and Ecotechnology 2024年第4期20卷 247-258页

作者： Guanshu Zhao jing Ding jiayi Ren Qingliang Zhao Chengliang Mao Kun Wang jessica Ye Xueqi Chen Xianjie Wang Mingce Long State Key Laboratory of Urban Water Resources and Environment School of EnvironmentHarbin Institute of TechnologyHarbin150090China Solar Fuels Group Department of ChemistryUniversity of Toronto80 St.George StreetTorontoOntarioM5S 3H6Canada School of Physics Harbin Institute of TechnologyHarbin150001China School of Environmental Science and Engineering Key Laboratory of Thin Film and Microfabrication Technology(Ministry of Education)Shanghai Jiao Tong University800 Dongchuan RoadShanghai200240China

The ubiquity of refractory organic matter in aquatic environments necessitates innovative removal *** radical-based advanced oxidation has emerged as an attractive solution,offering high selectivity,enduring efficacy,and anti-interference *** many technologies,sulfite activation,leveraging its cost-effectiveness and lower toxicity compared to conventional persulfates,stands ***,the activation process often relies on transition metals,suffering from low atom *** we introduce a series of single-atom catalysts(SACs)employing transition metals on g-C_(3)N_(4)substrates,effectively activating sulfite for acetaminophen *** highlight the superior performance of Fe/CN,which demonstrates a degradation rate constant significantly surpassing those of Ni/CN and Cu/*** investigation into the electronic and spin polarization characteristics of these catalysts reveals their critical role in catalytic efficiency,with oxysulfur radical-mediated reactions ***,under visible light,the catalytic activity is enhanced,attributed to an increased generation of oxysulfur radicals and a strengthened electron donation-back donation *** proximity of Fe/CN's d-band center to the Fermi level,alongside its high spin polarization,is shown to improve sulfite adsorption and reduce the HOMO-LUMO gap,thereby accelerating photo-assisted sulfite *** work advances the understanding of SACs in environmental applications and lays the groundwork for future water treatment technologies.

关键词： Single-atom catalysts(SACs) Oxysulfur radical Sulfite activation Spin polarization Electronic structure

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Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues

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Bioactive Materials 2023年第1期19卷 268-281页

作者： Arwa Daghrery jessica A.Ferreira jinping Xu Nasim Golafshan Darnell Kaigler Sarit B.Bhaduri jos Malda Miguel Castilho Marco C.Bottino Department of Cariology Restorative Sciencesand EndodonticsSchool of DentistryUniversity of MichiganAnn ArborMIUnited States Department of Restorative Dental Sciences School of DentistryJazan UniversityJazanKingdom of Saudi Arabia Department of Orthopedics University Medical Center UtrechtUtrechtthe Netherlands Regenerative Medicine Center Utrechtthe Netherlands Department of Periodontics and Oral Medicine School of DentistryUniversity of MichiganAnn ArborMIUnited States Department of Mechanical Industrial and Manufacturing EngineeringUniversity of ToledoToledoOHUnited States EEC Division Directorate of EngineeringThe National Science FoundationAlexandriaVAUnited States Department of Clinical Sciences Faculty of Veterinary MedicineUtrecht UniversityUtrechtthe Netherlands Department of Biomedical Engineering Eindhoven University of TechnologyEindhoventhe Netherlands Institute for Complex Molecular Systems Eindhoven University of TechnologyP.O.Box 5135600 MB Eindhoventhe Netherlands Department of Biomedical Engineering College of EngineeringUniversity of MichiganAnn ArborMIUnited States

Periodontitis is a chronic inflammatory condition that often causes serious damage to tooth-supporting *** limited successful outcomes of clinically available approaches underscore the need for therapeutics that cannot only provide structural guidance to cells but can also modulate the local immune ***,three-dimensional melt electrowritten(i.e.,poly(ε-caprolactone))scaffolds with tissue-specific attributes were engineered to guide differentiation of human-derived periodontal ligament stem cells(hPDLSCs)and mediate macrophage *** investigated tissue-specific scaffold attributes comprised fiber morphology(aligned ***)and highly-ordered architectures with distinct strand spacings(small 250μm and large 500μm).Macrophages exhibited an elongated morphology in aligned and highly-ordered scaffolds,while maintaining their round-shape on randomly-oriented fibrous *** of periostin and IL-10 were more pronounced on the aligned and highly-ordered *** hPDLSCs on the scaffolds with 500μm strand spacing show higher expression of osteogenic marker(Runx2)over 21 days,cells on randomly-oriented fibrous scaffolds showed upregulation of M1 *** an orthotopic mandibular fenestration defect model,findings revealed that the tissue-specific scaffolds(i.e.,aligned fibers for periodontal ligament and highly-ordered 500μm strand spacing fluorinated calcium phosphate[F/CaP]-coated fibers for bone)could enhance the mimicking of regeneration of natural periodontal tissues.

关键词： Periodontitis Melt electrowriting 3D printing Inflammation Periodontal regeneration Scaffold

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