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Fitness and health benefits of team handball training for young untrained women--A cross-disciplinary RCT on physiological adaptations and motivational aspects

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Journal of Sport and Health Science 2018年第2期7卷 139-148页

作者： Therese Hornstrup Johan M.Wikman Bjorn Fristrup Susana Povoas Eva W.Helge Signe H.Nielsen Jorn W.Helge jesper L.Andersen Lars Nybo Peter Krustrup Department of Nutrition Exercise and Sports University of Copenhagen Copenhagen N 2200 Denmark Research Center in Sports Sciences Health Sciences and Human Development CIDESD University Institute of Maia ISMAI Maia 4475-690 Portugal Center of Healthy Aging Department of Biomedical Sciences University of Copenhagen Copenhagen N 2200 Denmark Institute of Sports Medicine Copenhagen Bispebjerg Hospital Copenhagen NV 2400 Denmark Department of Sports Science and Clinical Biomechanics SDU Sport and Health Sciences Cluster (SHSC) University of Southern Denmark Odense 3450 Denmark Sport and Health Sciences University of Exeter Exeter EX1 2LU UK

Purpose: The present study evaluated the effects of regular participation in small-sided team handball training on body composition, osteogenic response, physical performance, and cardiovascular risk factors, as well as well-being and motivation, in young untrained ***: Twenty-eight untrained 20- to 30-year-old women were randomized to a handball training group(HG; n = 14, height 170 ± 5 cm, weight 73 ± 11 kg, VO_(2peak) 37.7 ± 4.1 mL/min/kg) that trained 1.7 ± 0.3 times per week over 12 weeks(70 min 4 v 4 handball sessions) or an inactive control group(CG; n = 14, 169 ± 5 cm, 71 ± 12 kg, 38.1 ± 3.7 mL/min/kg). Physiological and psychological and motivational training adaptations were assessed pre-and post-intervention by dual-energy X-ray Absorptiometry(DXA) scans, blood sampling, physical tests, and ***: The average heart rate(HR) over all training sessions was equal to 85% ± 6% HR_(max). Between-group intervention effects were observed in favor of HG for muscle mass(2.1%, p = 0.024), proximal femur bone mineral density(0.8%, p = 0.041), Yo-Yo IE1 intermittent endurance test level 1(IE1) performance(35%, p < 0.001), and incremental treadmill test performance(11.5%, p = 0.003), but not total fat mass(p = 0.176),mean arterial blood pressure(p = 0.328), resting HR(p = 0.219), or blood lipids(p = 0.298—0.854). In CG, no changes were observed in any of the measured physiological variables after the training period. Compared to CG, HG had an increase in intrinsic motivation(p < 0.001) and in the well-being subscale "energy"(p = 0.010).Conclusion: Participation in regular recreational team handball training organized as small-sided games has marked beneficial effects on physical performance, musculoskeletal fitness, well-being, and motivation in untrained young women.

关键词： Bone mineral density (BMD) Intensity Intermittent Motivation Muscle mass Physical performance Recreational handball Well-being

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Human-driven topographic effects on the distribution of forest in a flat, lowland agricultural region

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Journal of Geographical Sciences 2014年第1期24卷 76-92页

作者： Mette V. ODGAARD Peder K. BOCHER Tommy DALGAARD jesper E. MOESLUND Jens-Christian SVENNING Department of Agroecology Aarhus University Blichers AIIe 20 DK-8830 Tjele Denmark Ecoinformatics & Biodiversity Group Department of Bioscience Aarhus University Ny Munkegade 114DK-8000 Aarhus C Denmark Department of Computer Science Aarhus University Abogade 34 DK-8200 Aarhus N Denmark

Complex topography buffers forests against deforestation in mountainous regions. However, it is unknown if terrain also shapes forest distribution in lowlands where human impacts are likely to be less constrained by terrain. In such regions, if important at all, to- pographic effects will depend on cultural-historical factors and thus be human-driven （an- thropogenic） rather than natural, except in regions where the general climate or extreme soils limit the occurrence of forests. We used spatial regression modeling to assess the extent to which topographic factors explain forest distribution （presence-absence at a 48x48 m resolu- tion） in a lowland agricultural region （Denmark, 43,075 km2） at regional and landscape scales （whole study area and 10x10 km grid cells, respectively）, how landscape-scale for- est-topography relationships vary geographically, and which potential drivers （topographic heterogeneity, forest cover, clay content, coastal/inland location） determine this geographic heterogeneity. Given a moist temperate climate and non-extreme soils all landscapes in Denmark would naturally be largely forest covered, and any topographic relationships will be totally or primarily human-driven. At regional scale, topographic predictors explained only 5% of the distribution of forest. In contrast, the explanatory power of topography varied from 0%-61% at landscape scale, with clear geographic patterning. Explanatory power of topog- raphy at landscape scale was moderately dependent on the potential drivers, with topog- raphic control being strongest in areas with high topographic heterogeneity and little forest cover. However, these conditioning effects were themselves geographically variable. Our findings show that topography by shaping human land-use can affect forest distribution even in flat, lowland regions, but especially via localized, geographically variable effects.

关键词： Europe forest cover geographically weighted regression human impact landscape development topography vegetation distribution.

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Atrial Myxoma with a Dual Coronary Artery Supply

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International Journal of Clinical Medicine 2017年第6期8卷 368-374页

作者： Massar Omar jesper Eske Sindby Asta Blaskauskaite Tomas Zaremba Svend Eggert Jensen Department of Cardiology Aalborg University Hospital Aalborg Denmark Department of Thoracic Surgery Aalborg University Hospital Aalborg Denmark Department of Cardiology Hjorring Hospital Hjorring Denmark Department of Clinical Medicine Aalborg University Aalborg Denmark

Primary cardiac tumours are rare, with myxoma being the most common benign heart tumour. The prevalence of coronary disease or neovascular in patients with atrial myxomas is high, yet angiography is not routinely performed. Echocardiography is preferred for evaluation of myxoma, where coronary angiography clarifies the vascular supply of the tumour and may alter the surgical planning. We here report an interesting and rare case of a left atrial myxoma hyper vascularised by two anomalous arteries, from right coronary artery and circumflex artery demonstrated by preoperative coronary angiography. The mass was successfully excised and the diagnosis of cardiac myxoma was confirmed via histopathology. A review of the value of coronary angiography in detecting myxoma neovascularization is provided. Offering additional valuable information, coronary angiography can alter the surgical approach and may therefore be considered prior to myxoma resection.

关键词： Atrial Myxoma Cardiac Tumour Coronary Angiography Stroke Echocardiography Embolism Coronary Vascularisation Case Report

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Impacts of Climate Change on Growth Period and Planting Boundaries of Spring Wheat in China under RCP4.5 Scenario

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Journal of Resources and Ecology 2016年第1期7卷 1-11页

作者：孙侦贾绍凤吕爱锋 jesper Svensson 高彦春中国科学院地理科学与资源研究所中国科学院陆地水循环及地表过程重点实验室北京100101 中国科学院大学北京100049 麦克马斯特大学

This article contributes to research on how climate change will impact crops in China by moving from ex-post empirical analysis to forecasting. We construct a multiple regression model, using agricultural observations and meteorological simulations by GCMs, to simulate the possible planting boundaries and suitable planting re- gions of spring wheat under RCP4.5 scenario for the base period 2040s and 2070s. We find that the south bound- ary of possible planting region for spring wheat spreads along the belt： south Shandong-north Jiangsu-north Anhui-central Henan-north Hubei-southeast Sichuan-north Yunnan provinces, and will likely move northward under RCP4.5 scenario in 2040s and 2070s, resulting in the decrease of possible planting area in China. Moreover, the sowing and harvest date of spring wheat in the base period shows a gradually delayed phenomenon from the belt： south Xinjiang - Gansu, to the Tibet Plateau. As a result, the growth period of spring wheat in China will shorten because of the impacts of climate change. These results imply that a variety of adaptations measures should be set up in response to changing climatic conditions, including developing the planting base for spring wheat, restricting the planting area of spring wheat in sub-suitable areas at risk while expanding the planting area of optimal crops.

关键词： IPCC AR5 climate change spring wheat growth period possible planting boundary suitable region

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适用于各类锻造设备的模块化数字产品包

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锻造与冲压 2023年第13期 65-67页

作者： jesper Mellenthin 西马克集团

通过选用这套模块化的数字化产品包,锻造设备即可踏入数字化时代。帮助锻造行业从数据中创造价值,并不断提高工厂生产效率、产品质量、设备运转率和能源效率。所有解决方案都可以组合在一起,并适用于任何一家供应商的现有设备。自由锻... 详细信息

通过选用这套模块化的数字化产品包,锻造设备即可踏入数字化时代。帮助锻造行业从数据中创造价值,并不断提高工厂生产效率、产品质量、设备运转率和能源效率。所有解决方案都可以组合在一起,并适用于任何一家供应商的现有设备。自由锻和径向锻,其工艺过程和自动化程度差异很大。有一些锻造厂专门生产定制化的单体锻件,另一些锻造厂则高度自动化地大批量生产锻件,因此他们对数字化系统的要求各有不同。

关键词：锻造设备锻造厂自由锻设备运转率数字化系统锻造行业数字化产品工艺过程

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Developmental regulation of neuronal gene expression by Elongator complex protein 1 dosage

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Journal of Genetics and Genomics 2022年第7期49卷 654-665页

作者： Elisabetta Morini Dadi Gao Emily M.Logan Monica Salani Aram J.Krauson Anil Chekuri Yei-Tsung Chen Ashok Ragavendran Probir Chakravarty Serkan Erdin Alexei Stortchevoi jesper Q.Svejstrup Michael E.Talkowski Susan A.Slaugenhaupt Center for Genomic Medicine Massachusetts General Hospital Research InstituteBostonMAUSA Department of Neurology Massachusetts General Hospital Research Institute and Harvard Medical SchoolBostonMAUSA Program in Medical and Population Genetics and Stanley Center for Psychiatric Research Broad Institute of Harvard and MITCambridgeMAUSA Department of Life Sciences and Institute of Genome Sciences National Yang Ming Chiao Tung UniversityTaiwanChina Bioinformatics and Biostatistics The Francis Crick InstituteLondonUK Mechanisms of Transcription Laboratory The Francis Crick InstituteLondonUK Department of Cellular and Molecular Medicine Panum InstituteUniversity of CopenhagenCopenhagenDenmark

Familial dysautonomia(FD), a hereditary sensory and autonomic neuropathy, is caused by a mutation in the Elongator complex protein 1(ELP1) gene that leads to a tissue-specific reduction of ELP1 protein. Our work to generate a phenotypic mouse model for FD headed to the discovery that homozygous deletion of the mouse Elp1 gene leads to embryonic lethality prior to mid-gestation. Given that FD is caused by a reduction, not loss, of ELP1, we generated two new mouse models by introducing different copy numbers of the human FD ELP1 transgene into the Elp1 knockout mouse(Elp1) and observed that human ELP1 expression rescues embryonic development in a dose-dependent manner. We then conducted a comprehensive transcriptome analysis in mouse embryos to identify genes and pathways whose expression correlates with the amount of ELP1. We found that ELP1 is essential for the expression of genes responsible for nervous system development. Further, gene length analysis of the differentially expressed genes showed that the loss of Elp1 mainly impacts the expression of long genes and that by gradually restoring Elongator, their expression is progressively rescued. Finally, through evaluation of co-expression modules, we identified gene sets with unique expression patterns that depended on ELP1 expression.

关键词： ELP1 Elongator Transcriptional elongation Familial dysautonomia Neurodevelopmental disease

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A cis-Regulatory Sequence Acts as a Repressor in the Arabidopsis thaliana Sporophyte but as an Activator in Pollen

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Molecular Plant 2017年第5期10卷 775-778页

作者： Robert D. Hoffmann Lene I. Olsen Jeppe O. Husum jesper S. Nicolet Jens F.B. Thøfner Anders P. Wätjen Chukwuebuka V. Ezike Michael Palmgren Department of Plant and Environmental Sciences University of Copenhagen Thorvaldsensvej 40 1871 Frederiksberg C Denmark Department of Plant and Environmental Sciences Center for Membrane Pumps in Cells and Disease - PUMPKIN Danish National Research Foundation University of Copenhagen 1871 Frederiksberg C Denmark

Dear Editor, Flowering plants undergo a life cycle in which the diploid sporo- phyte constitutes the predominant generation, and the haploid male and female gametophytes are reduced to only a few but highly specialized cells （McCormick, 1993）. To achieve expression restricted to certain cell types, genes are not only actively expressed in these cells, they might also be repressed elsewhere. Here, we report that deleting an 88-base-pair （bp） promoter sequence of the pollen-specific gene ACA7 redirects its expression to the sporophyte.

关键词： Flowering plants life cycle diploid sporophyte constitutes

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厦门空中自行车道

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建筑实践 2019年第11期 94-99页

作者： MA Weiwei jesper Henriksen DISSING+WEITLING建筑师事务所

丹麦建筑师事务所Dissing+Weitling在厦门修建了世界上最长的高架自行车道——厦门空中自行车道,这使得在厦门通过自行车出行变得更加简单、安全、趣味盎然。空中自行车道长约8公里,沿厦门市中心已有的BRT线展开,位于BRT车道下方。空中... 详细信息

丹麦建筑师事务所Dissing+Weitling在厦门修建了世界上最长的高架自行车道——厦门空中自行车道,这使得在厦门通过自行车出行变得更加简单、安全、趣味盎然。空中自行车道长约8公里,沿厦门市中心已有的BRT线展开,位于BRT车道下方。空中自行车道覆盖了厦门市5大居住区、3大商业中心。全线有11个入口、11座公交车站和2个地铁站相连。其原型来自于丹麦举世闻名的自行车道——哥本哈根蛇形自行车天桥,并根据厦门当地独特的环境和路网状况进行了调整。

关键词：空中自行车建筑师事务所

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