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Different types of spin currents in the comprehensive materials database of nonmagnetic spin Hall effect

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npj Computational Materials 2021年第1期7卷 1522-1528页

作者： Yang Zhang Qiunan Xu Klaus Koepernik Roman Rezaev Oleg Janson Jakub Železný Tomáš Jungwirth Claudia Felser jeroen van den brink Yan Sun Max Planck Institute for Chemical Physics of Solids 01187 DresdenGermany Leibniz Institute for Solid State and Materials Research 01069 DresdenGermany Department of Physics Massachusetts Institute of TechnologyCambridgeMA 02139USA Institute of Physics Czech Academy of SciencesCukrovarnicka 1016200 Praha 6Czech Republic School of Physics and Astronomy University of NottinghamNG72RD NottinghamUnited Kingdom Center for Nanoscale Systems Faculty of Arts and SciencesHarvard University11 Oxford StreetLISE 308CambridgeMA 02138USA Institut fur Theoretische Physik and Wurzburg-Dresden Cluster of Excellence ct.qmat Dresden University of Technology01062 DresdenGermany

Spin Hall effect(SHE)has its special position in *** gain new insight into SHE and to identify materials with substantial spin Hall conductivity(SHC),we performed high-precision high-throughput ab initio calculations of the intrinsic SHC for over 20,000 nonmagnetic *** calculations revealed a strong relationship between the magnitude of the SHC and the crystalline symmetry,where a large SHC is typically associated with mirror symmetry-protected nodal line band *** database includes 11 materials with an SHC comparable to or even larger than that of *** with different types of spin currents were additionally ***,we found that different types of spin current can be obtained by rotating applied electrical *** improves our understanding and is expected to facilitate the design of new types of spin-orbitronic devices.

关键词： symmetry magnetic effect

Author Correction:Different types of spin currents in the comprehensive materials database of nonmagnetic spin Hall effect

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npj Computational Materials 2021年第1期7卷 1762-1763页

作者： Yang Zhang Qiunan Xu Klaus Koepernik Roman Rezaev Oleg Janson Jakub Železný Tomáš Jungwirth Claudia Felser jeroen van den brink Yan Sun Max Planck Institute for Chemical Physics of Solids 01187 Dresden Germany Leibniz Institute for Solid State and Materials Research 01069 Dresden Germany Department of Physics Massachusetts Institute of Technology Cambridge MA 02139 USA Center for Nanoscale Systems Faculty of Arts and Sciences Harvard University 11 Oxford Street LISE 308 Cambridge MA 02138 USA Institut fur Theoretische Physik and Wurzburg-Dresden Cluster of Excellence ct.qmat Dresden University of Technology 01062 Dresden Germany Institute of Physics Czech Academy of Sciences Cukrovarnicka 10 162 00 Praha 6 Czech Republic School of Physics and Astronomy University of Nottingham NG7 2RD Nottingham United Kingdom

The original version of this Article contained errors in Fig.3b,d,in which a factor of“100”should be included in the unit for both y-axis labels“SHC[100(ħ/e)(S/cm)]”.This has been corrected in both the PDF and HTM... 详细信息

关键词： database HTML include

A physically active lifestyle is related to a lower level of skin autofluorescence in a large population with chronic-disease(LifeLines cohort)

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Journal of Sport and Health Science 2022年第2期11卷 260-265页

作者： Saskia Corine van de Zande jeroen Klaas de Vries Inge van den Akker-Scheek Johannes Zwerver Andries Jan Smit Department of Internal Medicine Division of Vascular MedicineUniversity of GroningenUniversity Medical Center GroningenGroningen9700 RBthe Netherlands Department of Internal Medicine Antonius Hospital SneekSneek8601 ZKthe Netherlands Department of Orthopaedics University of GroningenUniversity Medical Center GroningenGroningen9700 RBthe Netherlands Center for Human Movement Sciences University of GroningenUniversity Medical Center GroningenGroningen9700 RBthe Netherlands Sports Valley Gelderse Vallei HospitalEde6716 RPthe Netherlands

Background:Physical activity(PA)has substantial health benefits and is important in combatting chronic diseases,which have been associated with elevated levels of advanced glycation endproducts(AGEs).AGEs play a role in the aging process,and an association between PA and AGEs has been *** aimed to investigate the relationship between PA and AGE accumulation in a general population and in a population with chronic ***:This large cross-sectional population study used data from adult participants in the LifeLines project,with participant information drawn from the LifeLines database as well data from patients with diabetes mellitus or renal and/or cardiovascular *** AGE accumulation was assessed non-invasively by skin-autofluorescence(SAF)using an AGE reader(DiagnOptics Technologies BV,Groningen,the Netherlands).PA was assessed using the short questionnaire to assess health-enhancing physical activity(SQUASH).Multivariate linear regression analyses were adjusted for age,body mass index,sex,and smoking ***:Data from 63,452 participants(general population n=59,177,chronic disease n=4275)were *** general population was significantly younger(43.58±11.77 years,mean±SD)and had significantly lower SAF(1.90±0.42 arbitrary units(AU))compared to the population with chronic disease(age:55.51±12.07 years;SAF:2.27±0.51 AU).In the group with chronic disease,more hours of moderate to vigorous physical activities per week were associated with lower SAF(β=-0.002,95%confidence interval(95%CI):-0.002 to-0.001).For the general population,there was no association between hours of moderate to vigorous activity and SAF(β=3.2×10^(-5),95%CI:0.000-0.001,p=0.742).However,there was an association in the general population between total hours of PA per week and SAF(β=4.2×10^(-4),95%CI:0.000-0.001,p<0.001),but this association was not found in the chronic disease population(β=-3.2×10^(-4),95%CI:-0.001 to 0.000,p=0.347).Conclusion:Our study demons

关键词： Advanced glycation endproducts Chronic disease population General population Physical activity Skin autofluorescence

Phylogeny of the industrial relevant,thermophilic genera Myceliophthora and Corynascus

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Fungal Diversity 2012年第1期52卷 197-207页

作者： Joost van den brink Robert A.Samson Ferry Hagen Teun Boekhout Ronald P.de Vries CBS-KNAW Fungal Biodiversity Centre P.O.Box 851673508 AD UtrechtThe Netherlands

Species of the genus Myceliophthora and its teleomorph Corynascus have attracted increasing interest due to their potential to produce thermostable *** study re-assessed the phylogenetic relationship of 49 isolates of nine species belonging to Myceliophthora and *** species,***,was shown not to belong to the genus Myceliophthora and should be placed in the genus *** other species belonged to two phylogenetic clusters:mesophilic fungi with the type species *** and ***,and thermophilic fungi with ***,*** and *** phylogenetic data provides no clear separation of the two genera Corynascus and *** avoid confusion in future taxonomic studies,it is proposed that all existing Corynascus species be renamed to Myceliophthora,which is the old name and the one more frequently ***,this study identified two groups within the isolates listed as *** and assigned one group(five isolates)to *** based on AFLP analysis and mating *** study provides new insights into the genetic differences within the genus Myceliophthora and will therefore be essential for the interpretation of future genomic and physiological studies of these species.

关键词： Myceliophthora Corynascus Thermophiles M.heterothallica M.thermophila.Thermophilic fungi Multigene phylogeny AFLP analysis Mating behavior

Multiple sclerosis:why we should focus on both sides of the(auto)antibody

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Neural Regeneration Research 2021年第12期16卷 2422-2424页

作者： jeroen den Dunnen Lynn Mes Willianne Hoepel Joost Smolders Amsterdam Rheumatology and Immunology Center Department of Rheumatology and Clinical ImmunologyDepartment of Experimental ImmunologyAmsterdam Institute for Infection and ImmunityAmsterdam UMCUniversity of AmsterdamAmsterdamThe Netherlands Department of Medical Microbiology Amsterdam institute for Infection and ImmunityAmsterdam UMCUniversity of AmsterdamAmsterdamThe Netherlands(Mes L)Neuroimmunology Research groupNetherlands Institute for NeuroscienceAmsterdamMS Center ErasMSDepartments of Neurology and ImmunologyErasmus Medical CenterRotterdamThe Netherlands

Various clinical and experimental findings suggest a pathogenic role of antibodies in multiple sclerosis(MS).Yet,whether antibodies contribute to the pathogenesis or progression of MS is still a subject of intense *** controversy particularly results from unclarity regarding the target antigens of the antibodies that are found in the central nervous system(CNS)of MS patients.

关键词： sclerosis antibodies clinical

Bone regeneration using coculture of mesenchymal stem cells and angiogenic cells

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Frontiers of Materials Science 2014年第1期8卷 32-38页

作者： Jin-Ling MA jeroen J. J. P. van den BEUCKEN Ju-Li PAN Fu-Zhai CUI Su CHEN Department of VIP Service Beijing Stomatological Hospital Capital Medical University Beijing 100050 China Department of Biomaterials Radboudumc Nijmegen the Netherlands Department of Oral and Maxillofacial Surgery Beijing Stomatological Hospital Capital Medical University Beijing 100050 China State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and Engineering Tsinghua University Beijing 100084 China

Cellular strategies remain a crucial component in bone tissue engineering （BTE）. So far, the outcome of cell-based strategies from initial clinical trials is far behind compared to animal studies, which is suggested to be related to insufficient nutrient and oxygen supply inside the Ussue-engineered constructs. Cocultures, by introducing angiogenic cells into osteogenic cell cultures, might provide a solution for improving vascularization and hence increasing bone formation for cell-based constructs. So far, pre-clinical studies demonstrated that cocultures enhance vascularization and bone formation compared to monocultures. However, there has been no report on the application of cocultures in clinics. Therefore, this mini-review aims to provide an overview regarding （i） critical parameters in cocultures and the outcomes of cocultures compared to monocultures in the currently available pre-clinical studies using human mesenchymal stem cells implanted in orthotopic animal models; and （ii） the usage of monocultures in clinical application in BTE.

关键词： mesenchymal stem cell (MSC) endothelial cell (EC) coculture vasculari-zation tissue regeneration

Three-dimensional modeling with national coverage:case of The Netherlands

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Geo-Spatial Information Science 2013年第4期16卷 267-276页

作者： Jantien STOTER Linda van den brink Jakob BEETZ Hugo LEDOUX Marcel REUVERS Paul JANSSEN Friso PENNING George VOSSELMAN Sander OUDE ELBERINK Kadaster Hofstraat 1107311ApeldoornThe Netherlands OTB-Section GIS Technology)Delft University of Technology Jaffalaan 92600 AADelftKZThe Netherlands Geonovum Barchman Wuytierslaan 103818 LH AmersfoortThe Netherlands Department of the Built Environment Eindhoven University of TechnologyVRT 9.08Postbus 5135600 MBEindhovenThe Netherlands Department GeoInformation City of The HagueThe Netherlands Faculty of Geo-Information Science and Earth Observation–ITC University of TwenteHengelosestraat 997514 AEEnschedeThe Netherlands

Three-dimensional technologies have matured over the *** the same time,3D information is becoming increasingly important in many *** it is not straightforward to apply the solutions that work on prototypes,small areas or for specific projects to 3D modeling of a whole *** the Netherlands,two initiatives are ongoing to address the issues of nation-wide 3D ***,the initiative that aims at establishing and implementing a national 3D standard for large-scale topography with support of all *** and maintaining the large-scale data are the responsibility of local governments(mainly municipalities).The second initiative is led by the Kadaster(the organization responsible for topographic mapping in the Netherlands)and aims at automatically generating a 3D version of the 1:10 k object-oriented data-set based on a smart combination of the two-dimensional data with high-resolution laser *** initiatives are presented in this paper including results,open issues,and future plans.

关键词： 3D modeling 3D standard country wide 3D mapping

Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis

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World Journal of Gastroenterology 2014年第44期20卷 16683-16689页

作者： Mattheus CB Wielenga Jooske F van Lidth de Jeude Sanne L Rosekrans Alon D Levin Monique Schukking Geert RAM D'Haens Jarom Heijmans Marnix Jansen vanesa Muncan Gijs R van den brink Tytgat Institute for Liver and Intestinal Research and Department of Gastroenterology and Hepatology Academic Medical Center Department of Pathology Academic Medical Center

AIM: To investigate if azathioprine could reduce adenoma formation in ApcMin/+, a mouse model of sporadic intestinal tumorigenesis.

关键词： Azathioprine Thiopurine Intestinal adenoma Polyp ApcMin Chemoprevention Lymphoma Colon cancer

Bone morphogenetic protein-2 is a negative regulator of hepatocyte proliferation downregulated in the regenerating liver

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World Journal of Gastroenterology 2006年第47期12卷 7621-7625页

作者： Cui-Ping Xu Wen-Min Ji Gijs R van den brink Maikel P Peppelenbosch Department of Digestive Diseases First Clinical College Shanxi Medical University Taiyuan 030001 Shanxi Province China Department of Gastroenterology & Hepatology Leiden University Medical Center Leiden The Netherlands Department of Cell Biology Faculty of Medical Sciences University of G--roningen G--roningen The Netherlands

AIM: To characterize the expression and dynamic changes of bone morphogenetic protein (BMP)-2 in hepatocytes in the regenerating liver in rats after partial hepatectomy (PH), and examine the effects of BMP-2 on proliferation of human Huh7 hepatoma cells. METHODS: Fifty-four adult male Wistar rats were randomly divided into three groups: A normal control (NC) group, a partial hepatectomized (PH) group and a sham operated (SO) group. To study the effect of liver regeneration on BMP-2 expression, rats were sacrificed before and at different time points after PH or the sham intervention (6, 12, 24 and 48 h). For each time point, six rats were used in parallel. Expression and distribution of BMP-2 protein were determined in regenerating liver tissue by Western blot analysis and immunohistochemistry. Effects of BMP-2 on cell proliferation of human Huh7 hepatoma cell line were assessed using an MTT ***: In the normal liver strong BMP-2 expression was observed around the central and portal veins. The expression of BMP-2 decreased rapidly as measured by both immunohistochemistry and Western blot analysis. This decrease was at a maximum of 3.22 fold after 12 h and returned to normal levels at 48 h after PH. No significant changes in BMP-2 immunoreactivity were observed in the SO group. BMP-2 inhibited serum induced Huh7 cell ***: BMP-2 is expressed in normal adult rat liver and negatively regulates hepatocyte proliferation. The observed down regulation of BMP-2 following partial hepatectomy suggests that such down regulation may be necessary for hepatocyte proliferation.

关键词： Bone morphogenetic protein-2 Partial hepatectomy Liver regeneration, Hepatocellular carcinoma