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Local-scale Governance： A Review of the Zambian Approach to Fisheries Management

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Journal of Agricultural science and Technology(B) 2015年第2期5卷 81-92页

作者： Lloyd Haambiya Emmanuel Kaunda jeremy Likongwe Daimon Kambewa Kagoli Muyangali Lake Tanganyika Fisheries Research Unit P.O. Box 420055 Mpulungu Zambia Department of Aquaculture and Fisheries science Lilongwe University of Agriculture and Natural Resources P.O. Box 219Lilongwe Malawi Department of Rural Development and Extension Lilongwe University of Agriculture and Natural Resources P.O. Box 219Lilongwe Malawi Department of Fisheries Ministry of Agriculture and Livestock P.O. Box 350100 Chilanga Zambia

Despite Zambia＇s recent policies for optimizing sustainable management of fisheries, their success has been modest in practice. Artisanal and industrial fleets have led to decline in fish catches in the presence of currently prescribed management possibilities. Among other factors, excessive fishing and unsustainable fishing methods attributed to common property and free access to the resources are key. The country adopted co-management approach to fisheries management in the 1990s with a view to improve the fisheries stocks through community enforcement of fishery management regulations. Neither the success of co-management has been easy to measure nor its results appreciated. In view of overfishing, it is required to continue providing a range of empirical evidence of area-specific co-management interventions as basis for designing realistic and innovative solutions for the nation. This implies that new policies and institutions need to be developed by research to understand fisheries systems and better promote sustainable trajectories. The following review recommendation to central government is a coherent approach that uses and crystallizes the multiple interests and skills of co-management stakeholders. Most stakeholder groups have been involved in an ad hoc fashion through workshops, public meetings and consultative processes mainly organized by Department of Fisheries. stakeholders should be involved from the design of the process to each step in the process, including the ongoing monitoring and evaluation. A form of memorandum of understanding is suggested. This will formally set out a process that acknowledges each stakeholder＇s interests and provide forums to facilitate discussion, consultation and monitoring of management activities.

关键词： Co-management overfishing government community stakeholder participation.

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大学里的12个高分秘诀

海外英语 2009年第11期 34-35页

作者： Lynn F.Jacobs jeremy s.Hyman

成绩是衡量学生优秀与否的重要标准。正如上班族的工资、棒球运动员的击球率、商品的价格一样,学生的成绩是衡量在校表现的一个重要客观指标。本期"直面留学",我们为您提供了12个得高分的秘诀,希望每位刚踏入大学的读者门门得A。

关键词：秘诀高分大学客观指标上班族运动员学生工资

Controversies in the management of primary sclerosingcholangitis

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World Journal of Hepatology 2016年第5期8卷 265-272页

作者： jeremy s Nayagam stephen P Pereira John Devlin Phillip M Harrison Deepak Joshi Institute of Liver studies King’s College HospitalLondon SE5 9RSUnited Kingdom Institute of Liver and Digestive Health University College LondonLondon NW3 2PFUnited Kingdom

Primary sclerosing cholangitis(PsC) remains a rare but significant disease, which affects mainly young males in association with inflammatory bowel disease. There have been few advances in the understanding of the pathogenesis of the condition and no therapeutics with proven mortality benefit aside from liver transplantation. There remain areas of controversy in the management of PsC which include the differentiation from other cholangiopathies, in particular immunoglobulin G4 related sclerosing cholangitis, the management of dominant biliary strictures, and the role of ursodeoxycholic acid. In addition, the timing of liver transplantation in PsC remains difficult to predict with standard liver severity scores. In this review, we address these controversies and highlight the latest evidence base in the management of PsC.

关键词： Immunoglobulin G4 related sclerosingcholangitis Cholangiocarcinoma Primary sclerosingcholangitis Liver transplantation Dominant strictures

Myofascial Foot Pain Following Uneventful Epidural Analgesia for Labor and Delivery

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Open Journal of Anesthesiology 2012年第1期2卷 11-13页

作者： Badie s. Mansour Gretchen M. Wienecke Jorge A. Cure jeremy T. Almon Alberto J. de Armendi 不详

Following an uneventful delivery under epidural analgesia, a 17 year old female patient was referred to the Pain Clinic because of numbness and pain of the left big toe for 2 and a half Months. An Orthopedic consultation had ruled out foot injury and concluded that the pain was radicular and secondary to nerve damage from the epidural analgesia. A Pain Clinic evaluation made the diagnosis of myofascial pain which was successfully treated with trigger pint block using normal saline.

关键词： Myofascial Pain Trigger Point Epidural Analgesia Delivery in Adolescent Local Infiltration Chronic Foot Pain

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儿童血栓性血小板减少性紫癜(英文)

中国当代儿科杂志 2012年第11期14卷 803-810页

作者： Melanie sTEELE 陳浩偉 jeremy sTEELE 陳錦泉劉廣洪 Michael G.DeGroote school of Medicine McMaster UniversityHamiltonOntarioCanada Thrombosis and Atherosclerosis Research Institute HamiltonOntarioCanada sUNY Upstate University Medical Center Golisano Children's HospitalSyracuseNew YorkUSA Department of Pediatrics McMaster UniversityHamiltonOntarioCanada

血栓性血小板减少性紫癜(TTP)在儿童病例中甚为少见,但如未能及时诊断及施予治疗,其后果则极为严重。其最常见之5种病症为:血小板减少、微血管溶血性贫血、急性肾衰竭、发热及中枢神经系统症状。但临床病例中,并不一定会同时出现上述5... 详细信息

血栓性血小板减少性紫癜(TTP)在儿童病例中甚为少见,但如未能及时诊断及施予治疗,其后果则极为严重。其最常见之5种病症为:血小板减少、微血管溶血性贫血、急性肾衰竭、发热及中枢神经系统症状。但临床病例中,并不一定会同时出现上述5种症状。故此医疗人员对此病必须有极高之警觉性。TTP之病理特征包括:外周血涂片可见裂体细胞,Coombs试验阴性,血清乳酸脱氢酶增高及中度或重度血小板减少。TTP发病机理主因缺乏ADAMTs13,从而引发微血管溶血性贫血及血小板减少。TTP可概括分为家族性TTP(Upshaw schulman综合征)和继发性TTP。家族性TTP是由于先天性ADAMTs13缺乏所致,其急性治疗法为血浆置换,当病情稳定后,可输注新鲜冰冻血浆以防止病情复发。继发性TTP是指患者因体内产生抗体而导致ADAMTs13功能减退,主要治疗方法亦为血浆置换,最新之临床文献显示rituxiamb对此症亦颇有治疗价值。

关键词：血栓性血小板减少性紫癜 ADAMTs13 血浆置换儿童

Peginterferon Lambda-1a, a New Therapeutic for Hepatitis C Infection, from Bench to Clinic

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Journal of Clinical and Translational Hepatology 2013年第2期1卷 116-124页

作者： Henrik Andersen Jeff Meyer jeremy Freeman sean E.Doyle Kevin Klucher Dennis M.Miller Diana Hausman Jan L.Hillson ZymoGenetics/Bristol-Myers squibb Seattle WA 98102 USA EMD serono Billerica MA USA Oncothyreon Inc. Seattle WA USA CPTxBio Woodinville WA USA

Chronic infection with hepatitis C virus (HCV) is estimated to affect approximately 3% of the world's population and cause 350,000 deaths each *** number of years,the standard of care has been combination therapy with recombinant alfa interferons—originally as native proteins but more recently as polyethyleneglycol-modified derivatives—and ribavirin,with the recent addition of an Ns3 protease inhibitor for HCV genotype ***,therapeutic alfa interferons are associated with a significant burden of treatment-limiting adverse events,including musculoskeletal and influenza-like symptoms,hematologic cytopenias,autoimmune disease,fatigue,and other neurologic *** 2003,a team at ZymoGenetics (now a fully owned subsidiary of Bristol-Myers squibb) and a second,independent group simultaneously identified a new class of interferons—the type Ⅲ lambda interferons—with near-identical activity to the type Ⅰ alfa interferons in hepatocytes but with an unrelated and less ubiquitous *** evaluation of the type Ⅲ interferon system demonstrated antiviral activity against HCV in vitro with limited activity in peripheral blood mononuclear cells and other nonhepatocyte cell types,supporting its development as a potentially better-tolerated therapy for viral *** lambda-1a (Lambda) is an investigational type Ⅲ therapeutic agent originally developed at ZymoGenetics that is currently in Phase 3 studies for the treatment of *** this review,we describe the selection of the Lambda molecule and its preclinical and early clinical development,and how the resulting data have helped to establish the differentiated safety profile for Lambda—with fewer influenza-like and musculoskeletal symptoms and less hematologic toxicity than the alfa interferons—that was seen in later studies.

关键词： Discovery HCV Interferonλ

Augmented anastomotic urethroplasty with buccal mucosa for post penile fracture urethral injury long segment bulbar urethral stricture review

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Asian Journal of Urology 2021年第3期8卷 337-339页

作者： shreya srivastava Alexandra L.Tabakin Kevin J.Chua Hiren V.Patel Joshua sterling Charles F.Polotti Arnav srivastava jeremy C.sinkin Hari s.G.R.Tunuguntla Division of Urology Department of SurgeryRutgers Robert Wood Johnson Medical SchoolNew BrunswickNJUSA Division of Plastic and Reconstructive surgery Department of SurgeryRutgers Robert Wood Johnson Medical SchoolNew BrunswickNJUSA

Dear editor,The national incidence of penile fracture in the United states is estimated as 1.02 per 100000 males[1].Nine to twenty percent of these injuries result in a concomitant urethral injury[2,3].Barros et al.[4]reported that 85 out of 888 penile fractures men with penile fractures had concomitant urethral injuries[4].Among those with both a penile fracture and urethral injury,only two cases of urethral stricture were ***,only three percent of urethral strictures resulted from penile fractures[5].These data highlight the relatively low incidence of urethral stricture in patients with penile fracture and concomitant urethral injury.

关键词： urethral injuries stricture

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13个讨老师喜欢的方法

海外英语 2009年第12期 34-35页

作者： Lynn F.Jacobs jeremy s.Hyman

在学校里,那些讨老师喜欢的学生总是能得到更多的帮助,无论是在学习上还是找工作的过程中。老师愿意花时间来培养他们喜爱的学生,也乐意为其写一份好的就业推荐书。那么,怎样才能成为讨老师喜欢的学生呢?请看本期直面留学。

关键词：老师就业推荐学生学校学习留学

Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma

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signal Transduction and Targeted Therapy 2023年第5期8卷 2329-2344页

作者： Junhui Hu Ping Tan Moe Ishihara Nicholas ABayley shiruyeh schokrpur jeremy GReynoso Yangjun Zhang Raymond JLim Camelia Dumitras Lu Yang steven MDubinett Parmjit sJat Jacques Van snick Jiaoti Huang Arnold IChin Robert MPrins Thomas GGraeber Hua Xu Lily Wu Department of Molecular and Medical Pharmacology David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCA90095USA Department of Urology West China HospitalChengduChina Department of Hematology and Oncology University of California San DiegoSan DiegoCA92103USA Department of Neurosurgery David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCA90095USA Department of Biological Repositories Department of UrologyZhongnan Hospital of Wuhan UniversityWuhanChina Department of Medicine David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCA90095USA Jonsson Comprehensive Cancer Center David Geffen School of Medicine at UCLAUniversity of California Los AngelesLos AngelesCA90095USA MRC Prion Unit at UCL Institute of Prion Diseases33 Cleveland StreetLondonW1W 7FFUK Ludwig Institute for Cancer Research Ltd BrusselsBelgium Department of Pathology Duke UniversityDurhamNCUSA Department of Urology David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCA90095USA Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center WuhanChina

Loss of function of the von Hippel-Lindau(VHL)tumor suppressor gene is a hallmark of clear cell renal cell carcinoma(ccRCC).The importance of heterogeneity in the loss of this tumor suppressor has been under *** study the impact of intratumoral VHL heterogeneity observed in human ccRCC,we engineered VHL gene deletion in four RCC models,including a new primary tumor cell line derived from an aggressive metastatic *** VHL gene-deleted(VHL-KO)cells underwent epithelial-to-mesenchymal transition(EMT)and exhibited increased motility but diminished proliferation and tumorigenicity compared to the parental VHL-expressing(VHL+)*** tumors with either VHL+or VHL-KO cells alone exhibit minimal metastatic *** tumors displayed rampant lung metastases,highlighting a novel cooperative metastatic *** poorly proliferative VHL-KO cells stimulated the proliferation,EMT,and motility of neighboring VHL+***(POsTN),a soluble protein overexpressed and secreted by VHL non-expressing(VHL−)cells,promoted metastasis by enhancing the motility of VHL-WT cells and facilitating tumor cell vascular *** deletion or antibody blockade of POsTN dramatically suppressed lung metastases in our preclinical *** work supports a new strategy to halt the progression of ccRCC by disrupting the critical metastatic crosstalk between heterogeneous cell populations within a tumor.

关键词： VHL metastasis motility