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教学-教学实验-科研三位一体的学生培养模式的探究

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科技视界 2019年第28期 98-98,53页

作者：杨萍胡亚娥茅家慧朱燕李小青南通大学医学院<护理学院>

“科学技术是第一生产力”的提出让大众意识到科研的重要性。医疗技术的进步得益于基础医学和临床医学的研究,大大减轻了病人的痛苦,提高了各种疾病的生存率;交通工具的发展得益于理工科的研究,极大的便利了人们的生活,改善了群众的生... 详细信息

“科学技术是第一生产力”的提出让大众意识到科研的重要性。医疗技术的进步得益于基础医学和临床医学的研究,大大减轻了病人的痛苦,提高了各种疾病的生存率;交通工具的发展得益于理工科的研究,极大的便利了人们的生活,改善了群众的生活质量;通信的发展得益于信息技术的研究,使人们的沟通效率大大的提高,加快了社会发展和人们的生活节奏。诸如此类的例子不胜枚举,各行各业的发展都离不开科研。如何从本科阶段做起,培养科研型人才是高校教师需要思考的问题。本文从国内高校教育现状出发,提出培养科研型人才的几点建议,以期能为科研型人才的培养提供思路。

关键词：教学科研科研型人才

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利用啤酒酵母提取RNA的氨法工艺研究Ⅱ

药物生物技术 2000年第1期7卷 35-37页

作者：毛宁洪智勇张岩芳黄谚谚吴松刚福建师范大学生物工程学院福州350007

采用氨法破壁提取RNA ,当酵母质量分数为 10 % ,氨为 1 0 %时 ,采用分步沉淀法 ,调蛋白质的等电点后 ,再加入复合蛋白质沉淀剂去除蛋白质 ,可获得纯度在 83%的优质酵母RNA ,核酸的提取率是干酵母的2 %以上。

关键词：啤酒酵母 RNA 氨法工艺

Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic

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Stroke & Vascular Neurology 2021年第4期6卷 542-552,I0026-I0032页

作者： Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fuj.naka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby j.hn Emma Griffin j.hn Thornton j.se Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal j.bbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj.Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-j.hani Sunil A Sheth Victor S Lopez Rivera j.mes E Siegler Achmad Fidaus Sani Aj.t S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Aj.y K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brij.sh P Mehta Naoto Kimura Mamoru Murakami j.n Soo Lee j. Man Hong Robert Fahed Gregory Walker Eij. Hagashi Steve M Cordina Hong Gee Roh Ken Wong j.an F Arenillas Mario Martinez-Galdamez j.rdi Blasco Alej.ndro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon j.hn Alex Brehm Marios Psychogios William j.Mack Matthew Tenser Tatemi Todaka Miki Fuj.mura Roberta Novakovic j.n Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters j.hnny Wong Mohamed Teleb jeremy Payne Hiroki Fukuda Kosuke Miyake j.nsuke Shimbo Yusuke Sug Neurology RadiologyBoston Medical CenterBostonMassachusettsUSA Neurology Marcus Stroke&Neuroscience CenterGrady Memorial HospitalEmory University School of MedicineAtlantaGAUSA Radiology Radiation OncologyBoston University School of MedicineBostonMassachusettsUSA Neurology National Hospital Organization Osaka National HospitalOsakaJapan Neurosurgery National Hospital Organization Osaka National HospitalOsakaJapan Neurology Alexandria UniversityAlexandriaEgypt Radiology Boston Medical CenterBostonMassachusettsUSA Department of Neurology Xinqiao HospitalChongqingChina Neurosurgery University of Cape TownRondeboschWestern CapeSouth Africa Neurosurgery Interventional NeuroradiologyClinica La Sagrada FamiliaBuenos AiresArgentina Neuroradiologie Neurologie VasculaireHospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Neurologie Vasculaire Hospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Interventional Neuroradiology Fondation Ophtalmologique Adolphe de RothschildParisÎle-de FranceFrance Neurology Hospital Geral de FortalezaFortalezaBrazil Interventional Neuroradiology Hospital Geral de FortalezaFortalezaBrazil Neuroradiology Nottingham University Hospitals NHS TrustNottinghamUK Department of Neurosurgery Kobe City Medical Center General HospitalKobeHyogoJapan Interventional Neurovascular Unit University Hospital CareggiFirenzeToscanaItaly Neuroradiology University Hospital Centre ZagrebZagrebCroatia Interventional Neuroradiology Hopital BicetreLe Kremlin-BicetreFrance Stroke and Interventional Neuroradiology Lahore General HospitalLahorePakistan Neurological Institute Cleveland Clinic Abu DhabiAbu DhabiUAE Department of Radiology Beaumont HospitalDublinIreland Neurology Stroke UnitHospital-Estadual CentralVitoriaBrazil Neuroradiology Instituto de Neurocirugia Dr AsengoSantiagoChile Interventional Neuroradiology Institut National de NeurologieTunisTunisia Neurology Boston Medical CenterBostonMassachusettsUSA Neurosurgery Boston Medical Center

Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were *** study’s obj.ctive was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar *** We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke *** with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,*** 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May *** prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal *** There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,p<0.0001).Embolisation of ruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative *** analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,p<0.0001).A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this *** There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 *** findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction.

关键词： diagnosis representing subarachnoid

A Method for Detecting Adhesive Related-Factors of Streptococcus suis Serotype 2 by Real-time PCR

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Agricultural Science & Technology 2013年第10期14卷 1378-1382页

作者：汪伟何孔旺倪艳秀周俊明张雪寒俞正玉吕立新茅爱华温立斌王小敏李彬郭容莉江苏省农业科学院兽医研究所农业部兽用生物制品工程技术重点实验室国家兽用生物制品工程技术研究中心江苏南京210014

[Obj.ctive] This study aimed to establish a method for quantitative detection of mRNA transcriptional level of SS2 adhesive related-factors of Streptococcus suis serotype 2 （SS2） by fluorescent quantitative PCR. []Vlethod] The gene fragments en- coding SS2 adhesive related-factors MRP, FBPS and CPS2j.and a housekeeping gene aroA were amplified by reverse transcription PCR from the total RNA of SS2, cloned, and sequenced. The recombinant plasmids containing the target genes were constructed, and used as templates in Real-time PCR. [Result] Dynamic curves, stan- dard curves and melting curves of the adhesive related-factors and aroA were ob- tained by the optimized Real-time PCR system. The standard curves showed a good linear relationship between template copy number and circulation number, and the correlation coefficients （FF） of the standard curves were over 0.995. Also, these as- says were highly specific a^d there was single specific melting peak for every gene. Moreover, the assays were highly sensitive and had a detection limit of 1.0×102 copies in 1 μl of initial templates. Finally, it was highly repeatable and had a coeffi- cient of variation less than 2% for intra-assay. [Conclusion] This study will provide a way to reveal the adhesion mechanism of SS2 to different host cells at molecular level.

关键词： Streptococcus suis serotype 2 Adhesive related-factors (adhesins) Real- time PCR

Flux variations of cosmic ray air showers detected by LHAASO-KM2A during a thunderstorm on j.ne 10,2021

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Chinese Physics C 2023年第1期47卷 193-203页

作者： F.Aharonian 安琪阿西克古白立新白云翔包逸炜 D.Bastieri 毕效军毕玉江蔡金庭曹喆曹臻常进常劲帆陈恩生陈良陈亮陈龙陈明君陈玛丽陈素弘陈松战陈天禄陈学健陈阳程皓麟程宁程耀东崔树旺崔晓红崔昱东戴本忠代洪亮戴子高单增罗布 D.della Volpe 段凯凯樊军辉范一中范志香方军方堃冯存峰封莉冯少辉丰晓婷冯有亮高博高川东高林青高启高卫高伟康葛茂茂耿利斯龚光华苟全补顾旻皓郭福来郭俊广郭晓磊郭义庆郭莹莹韩毅昂何会海贺昊宁何思乐何新波何钰 M.Heller 贺远强侯超侯贤胡红波胡铨胡森胡世聪呼晓军黄代绘黄文昊黄性涛黄晓渊黄勇黄志成季筱璐贾焕玉贾康江琨姜泽军金敏康明铭柯通 D.Kuleshov 李兵兵李澄李骢李飞李海波李会财李华阳李军李剑李捷李凯李文龙李秀荣李昕李新李一卓李哲黎卓梁恩维梁云峰林苏杰刘冰刘成刘栋刘虎刘海东刘佳刘江来刘佳松刘金艳刘茂元柳若愚刘四明刘伟刘怡刘以农龙文杰鲁睿罗晴吕洪魁马伯强马玲玲马欣华毛基荣 A.Masood 闵振 W.Mitthumsiri 南云程区子维庞彬宇 P.Pattarakij.anich 裴致远齐孟尧祁业情乔冰强秦家军 D.Ruffolo A.Sáiz 邵澄宇邵琅 O.Shchegolev 盛祥东石京燕宋慧超 Yu.V.Stenkin V.Stepanov 苏扬孙秦宁孙晓娜孙志斌谭柏轩唐泽波田文武王博东王超王辉王洪光王建成王界双王利苹王玲玉王冉王润娜王为王祥高王祥玉王阳王玉东王岩谨王亚平王忠海王仲翔王振王铮韦大明魏俊杰魏永健文韬吴超勇吴含荣武莎吴雪峰吴雨生席邵强夏捷夏君集项光漫肖迪泫肖刚辛广广辛玉良邢祎熊峥徐东莲徐仁新薛良闫大海颜景志杨朝文杨冯帆杨何文杨佳盈杨莉莉杨明洁杨睿智杨深邦姚玉华姚志国叶一锰尹丽巧尹娜游晓浩游智勇于艳红袁强岳华曾厚敦曾婷轩曾玮曾宗康查敏翟徐徐张彬彬张丰张海明张恒英张建立张丽霞张力张路张鹏飞张佩佩张瑞张少博张少如张寿山张潇张笑鹏张云峰张月雷张毅张勇赵兵赵静赵雷赵立志赵世平郑福郑应周斌周浩周佳能周平周荣周勋秀祝成光祝凤荣朱辉朱科军左雄 Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center of Sciences Beijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduSichuanChina Dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland Max-Planck-Institut for Nuclear Physics P.O.Box 10398069029 HeidelbergGermany State Key Laboratory of Particle Detection and Electronics China University of Science and Technology of China Hefei 230026China School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China College of Physics Sichuan UniversityChengdu 610065China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Key Laboratory of Dark Matter and Space Astronomy&Key Laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Key Laboratory of Cosmic Rays(Tibet University) Ministry of Education850000 LhasaTibetChina National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Hebei Normal University Shijiazhuang 050024China School of Physics and Astronomy(Zhuhai)&School of Physics(Guangzhou)&Sino-French Institute of Nuclear Engineering and Technology(Zhuhai) Sun Yat-sen University519000 Zhuhai&510275 GuangzhouGuangdongChina Dipartimento di Fisica dell’Universitàdi Napoli"Federico II" Complesso Universitario di Monte Sant’Angelovia Cinthia80126 NapoliItaly School of Physics and Astronomy Yunnan UniversityKunming 650091China D´epartement de Physique Nucléaire et Corpusculaire Facultéde SciencesUniversitéde Genève24 Quai Ernest Ansermet1211 GenevaSwitzerland Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China Depar

The Large High Altitude Air Shower Observatory(LHAASO)has three sub-arrays,KM2A,WCDA,and *** flux variations of cosmic ray air showers were studied by analyzing the KM2A data during a thunderstorm on j.ne 10,*** number of shower events that meet the trigger conditions increases significantly in atmospheric electric fields,with a maximum fractional increase of 20%.The variations in trigger rates(increases or decreases)were found to be strongly dependent on the primary zenith *** flux of secondary particles increased significantly,following a trend similar to that of shower *** better understand the observed behavior,Monte Carlo simulations were performed with CORSIKA and G4KM2A(a code based on GEANT4).We found that the experimental data(in saturated negative fields)were in good agreement with the simulations,assuming the presence of a uniform electric field of-700 V/cm with a thickness of 1500 m in the atmosphere above the observation *** to the acceleration/deceleration by the atmospheric electric field,the number of secondary particles with energy above the detector threshold was modified,resulting in the changes in shower detection rate.

关键词： thunderstorm cosmic rays extensive air showers LHAASO-KM2A

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大岗山四种林型夏秋季土壤呼吸研究

江西农业大学学报 2007年第1期29卷 72-76,84页

作者：张连举王兵刘苑秋陈滨敖剑云江西农业大学园林与艺术学院江西南昌330045 中国林业科学研究院森林生态环境与保护研究所北京100091 乐安县林业局江西乐安344300

森林类型的转换必然会影响到森林碳循环模式,通过比较亚热带地区4种常见林型即常绿阔叶林、针阔混交林、杉木林、毛竹林在生长季土壤呼吸的差异,揭示林型改变对土壤碳库碳输出过程的影响。研究结果显示,在生长季常绿阔叶林、针阔混交林... 详细信息

森林类型的转换必然会影响到森林碳循环模式,通过比较亚热带地区4种常见林型即常绿阔叶林、针阔混交林、杉木林、毛竹林在生长季土壤呼吸的差异,揭示林型改变对土壤碳库碳输出过程的影响。研究结果显示,在生长季常绿阔叶林、针阔混交林、杉木林、毛竹林平均土壤呼吸值(CO2)差异显著,分别为4.28,3.51,2.28,5.37μmol/(m2.s)。4种林型土壤呼吸变化动态规律类似,从6月份开始升高,在7月或者8月达到峰值,然后开始下降,10月份土壤温度大幅下降,土壤呼吸也达到一个低谷。4种林型的土壤呼吸日变化均不明显。4种林型的土壤呼吸速率均与土壤温度呈显著相关关系,除杉木林外,另3种林型的土壤呼吸与土壤湿度相关关系不显著。

关键词：土壤呼吸常绿阔叶林针阔混交林杉木林毛竹林

Small P values may not yield robust findings:an example using REST-meta-PD

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Science Bulletin 2021年第21期66卷 2148-2152,M0003页

作者： Xi-Ze j.a Na Zhao Hao-Ming Dong j.a-Wei Sun Marek Barton Roxana Burciu Nicolas Carrière Antonio Cerasa Bo-Yu Chen j.n Chen Stephen Coombes Luc Defebvre Christine Delmaire Kathy Duj.rdin Fabrizio Esposito Guo-Guang Fan Federica Di Nardo Yi-Xuan Feng Brett W.Fling Saurabh Garg Moran Gilat Martin Gorges Shu-Leong Ho Fay BHorak Xiao Hu Xiao-Fei Hu Biao Huang Pei-Yu Huang Ze-j.an j.a Christina j.nes j.n Kassubek Lenka Kraj.ovicova Aj.y Kurani j.ng Li Qing Li Ai-Ping Liu Bo Liu Hu Liu Wei-Guo Liu Renaud Lopes Yu-Ting Lou Wei Luo Tara Madhyastha Ni-Ni mao Grainne McAlonan Martin j.McKeown Shirley Pang Andrea Quattrone Irena Rektorova Alessia Sarica Hui-Fang Shang j.mes M.Shine Priyank Shukla Tomas Slavicek Xiao-Peng Song Gioacchino Tedeschi Alessandro Tessitore David Vaillancourt j.an Wang j.e Wang Z.j.ne Wang Lu-Qing Wei Xia Wu Xiao-j.n Xu Lei Yan j.ng Yang Wan-Qun Yang Nai-Lin Yao De-Long Zhang j.u-Quan Zhang Min-Ming Zhang Yan-Ling Zhang Cai-Hong Zhou Chao-Gan Yan Xi-Nian Zuo Mark Hallett Tao Wu Yu-Feng Zang Center for Cognition and Brain Disorders the Affiliated HospitalHangzhou Normal UniversityHangzhou 310015China Zhej.ang Key Laboratory for Research in Assessment of Cognitive Impairments Hangzhou 311121China National Basic Science Data Center Beijing 100190China State Key Laboratory of Cognitive Neuroscience and Learning&McGovern Institute for Brain Research Beijing Normal UniversityBeijing 100875China School of Information and Electronics Technology Jiamusi UniversityJiamusi 154007China Neuroscience Program Central European Institute of TechnologyCEITECMasaryk UniversityBrno 62500Czech Republic Department of Applied Physiology and Kinesiology University of FloridaGainesville FL 32611USA Univ.Lille InsermCHU LilleU1172-LilNCog-Lille Neuroscience&CognitionLille F-59000France The Institute for Biomedical Research and Innovation National Research CouncilMangone CS 87050Italy Department of Radiology The First Affiliated Hospital of China Medical UniversityShenyang 110001China Department of Radiology Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510120China Department of Medicine Surgery and DentistryScuola Medica SalernitanaUniversity of SalernoFiscianoSA 132-84084Italy Department of Advanced Medical and Surgery Sciences University of Campania“Luigi Vanvitelli”Caserta 81100Italy Eye Center of the 2nd Affiliated Hospital Medical College of Zhejiang UniversityHangzhou 310020China Zhej.ang Provincial Key Lab of Ophthalmology Hangzhou 310020China Department of Health and Exercise Science Colorado State UniversityFort Collins CO 80523USA Pacific Parkinson’s Research Centre University of British ColumbiaVancouver BC V6E 2M6Canada Department of Medicine(Neurology)University of British Columbia Vancouver BC V6T 1B7Canada Brain and Mind Center The University of SydneySydney NSW 2006Australia Department of Neurology Ulm UniversityUlm 89081Germany Division of Neurology Department of MedicineQueen Mary HospitalUniversity of Hong KongHong Kong 999077China Department of

Thousands of resting state functional magnetic resonance imaging(RS-f MRI)articles have been published on brain *** precise localization of abnormal brain activity,a voxel-level comparison is *** of the large number of voxels in the brain,multiple comparison correction(MCC)must be performed to reduce false positive rates,and a smaller P value(usually including either liberal or stringent MCC)is widely recommended[1].

关键词：帕金森病 precise correction

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检测端粒酶活性在肺癌早期诊断中的价值

中国肺癌杂志 2001年第1期4卷 37-40页

作者：古涛王绪王秀英王伟刘永张蓓史艳侠张中明孙全胜薛涛张孝轩刘志发朱述阳毛筱芬徐州医学院肿瘤学教研室 221002 徐州医学院附属医院中心实验室徐州医学院生化与分子生物学中心徐州医学院附属医院心胸外科徐州医学院附属医院病理科徐州医学院附属医院呼吸内科

目的　探讨端粒酶作为肺癌肿瘤标记物的可能性 ,评价端粒酶活性对肺癌的早期诊断价值。方法　采用改良银染 -端粒重复序列扩增法 (TRAP)检测 40例原发性支气管肺癌手术标本及 40例CT扫描疑诊为肺癌患者的纤维支气管镜活检标本的端粒酶... 详细信息

目的　探讨端粒酶作为肺癌肿瘤标记物的可能性 ,评价端粒酶活性对肺癌的早期诊断价值。方法　采用改良银染 -端粒重复序列扩增法 (TRAP)检测 40例原发性支气管肺癌手术标本及 40例CT扫描疑诊为肺癌患者的纤维支气管镜活检标本的端粒酶活性。结果　两组中小细胞肺癌端粒酶阳性率均为 10 0 % ,非小细胞肺癌分别为 84.8%、95 .7%。 40例手术切除肺癌组织的端粒酶阳性率为 87.5 % ( 3 5 /40 ) ,癌旁肺组织为7.5 % ( 3 /40 ) ,正常肺组织无表达 ( 0 /40 ) ,三组间比较有显著性差异 (P j.=0 .678,SE(j. =0 .174。结论　端粒酶是灵敏的肺癌肿瘤标记物 ,对纤维支气管镜活检标本行端粒酶活性检测有助于肺癌的早期诊断。

关键词：肺肿瘤端粒酶早期诊断

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髌骨骨巨细胞瘤1例

临床骨科杂志 2020年第1期23卷 74-74页

作者：刘鹏王碧雯曹国定赵茂盛甄平甘肃中医药大学研究生院甘肃兰州730000 联勤保障部队第940医院关节外科甘肃兰州730050

患儿,女,14岁,摔倒致右膝疼痛剧烈,摔伤后4 h就诊。门诊CT检查显示:右髌骨病理性骨折。骨科门诊遂以“右髌骨病理性骨折”收住入院。膝关节X线检查:右侧髌骨骨质改变,考虑良性肿瘤合并病理性骨折,见图1A。CT检查:右侧髌骨呈膨胀性生长... 详细信息

患儿,女,14岁,摔倒致右膝疼痛剧烈,摔伤后4 h就诊。门诊CT检查显示:右髌骨病理性骨折。骨科门诊遂以“右髌骨病理性骨折”收住入院。膝关节X线检查:右侧髌骨骨质改变,考虑良性肿瘤合并病理性骨折,见图1A。CT检查:右侧髌骨呈膨胀性生长致骨质破坏,其内多发条状高密度影及软组织密度影,考虑良性骨肿瘤致病理性骨折,见图1B。

关键词：骨巨细胞瘤髌骨骨肿瘤