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Comparative study on various dielectric barriers and their effect on breakdown voltage

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High Voltage 2018年第1期3卷 51-59页

作者： Elham Foruzan Amir A.S.Akmal Kaveh Niayesh jeremy lin Desh Deepak Sharma Department of Electrical and Computer Engineering University of Nebraska-LincolnLincolnNE 68588USA Department of Electrical and Computer Engineering University of TehranTehranIran Department of Electric Power Engineering Norwegian University of Science and TechnologyTrondheimNorway PJM Interconnection AudubonPA 19403USA Department of Electrical Engineering MJP Rohilkhand UniversityBareilly(UP)India

Non-pressurised air is extensively used as basic insulation medium in high-voltage ***,an inherent property of air-insulated design is that the system tends to become physically *** the other hand,the application of dielectric barriers can increase the breakdown voltage and therefore decrease the size of the *** this study,the impact of dielectric barriers on breakdown voltage enhancement is investigated under both direct current(dc)and alternating current(ac)applied *** this purpose,three kinds of dielectric barriers in two different high-voltage electrode structures are *** the first structure,several experiments are carried out with four different electrode arrangements,keeping the inter-electrode gap constant while varying the position of the dielectric barrier between the *** the second structure,the inter-electrode gap is varied while the high-voltage electrode is covered with dielectric *** influences of different parameters such as inter-electrode spacing,electric field non-uniformity factor,and dielectric materials on the breakdown voltage are investigated for applied 50 Hz ac and dc *** addition,a simulation model to approximately calculate the breakdown voltage is proposed and validated with the experimental results.

关键词： breakdown dielectric electrode

Improvements in energy saving and thermal comfort for electric vehicles in summer through coupled electrochromic and radiative cooling smart windows

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Building Simulation 2024年第8期17卷 1231-1251页

作者： Zhoujie Duan Shuangdui Wu Hongli Sun Borong lin Pei Ding Tao Cui jeremy To Xi Zhang College of Architectureand Environment Sichuan UniversityChengdu610065China Department of Building Science Tsinghua UniversityBeijing 100084China KeyLaboratoryofEco Planning&Green Building MinistryofEducationTsinghua UniversityBeijing100084China State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan UniversityChengdu 610065China School of EmergencyManagement Xihua UniversityChengdu 610039China Department of PSVD Mercedes-benz Group China Ltd.Beijing 100102China

In hot climates,the large amount of cooling load in electric vehicle(EV)results in a lot of battery energy consumption,leading the decrease of driving *** the widespread application of windows in EV,the electrochromic glass(EC)shows great prospect in lowering the cooling ***,researches on the application of EC in EV lack the consideration of both passive cooling measures and passenger comfort,which limits the further application of *** this paper,we proposed an idea combining the novel techniques of both electrochromism and radiative *** fluid dynamics(CFD)is modeled to simulate the application of electrochromic and radiative cooling coupled smart windows in hot parking conditions,exploring the improvement effect of the window on the thermal environment,comfort and energy saving of the *** results indicate that,under the intense sunlight with an outdoor temperature of 33℃,activating the air conditioning to maintain an average interior temperature of 26℃,the coupled windows reduced the cooling capacity of the air conditioning by 762 W compared to regular windows,which can further increase the range of ***,compared to simple electrochromic fully colored glass,the integration of radiative cooling technology can lower the window surface temperature by up to 10.7℃.Moreover,compared to regular windows,the coupled windows lowered the standard effective temperature(SET*)for passengers by approximately 7℃,significantly improving *** research findings are expected to provide guidance for optimizing window design and enhancing the performance of EV.

关键词： electrochromism radiative cooling smart windowel ectric vehicle cabin thermal comfort energy saving

Metal to insulator transition for conducting polymers in plasmonic nanogaps

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Light(Science & Applications) 2024年第1期13卷 23-32页

作者： Yuling Xiong Rohit Chikkaraddy Charlie Readman Shu Hu Kunli Xiong Jialong Peng Qianqi lin jeremy J.Baumberg NanoPhotonics Centre Cavendish LaboratoryDepartment of PhysicsUniversity of CambridgeCambridgeCB30HEUK School of Physics&Astronomy University of BirminghamEdgbastonBirminghamUK College of Advanced Interdisciplinary Studies and Hunan Provincial Key Laboratory of Novel Nano-Optoelectronic Information Materials and Devices National University of Defense TechnologyChangshaChina Hybrid Materials for Opto-Electronics Group Department of Molecules and MaterialsMESA+Institute for NanotechnologyMolecules Center and Center for Brain-Inspired Nano SystemsFaculty of Science and TechnologyUniversity of TwenteEnschedeNetherlands

Conjugated polymers are promising material candidates for many future applications in flexible displays, organic circuits, and sensors. Their performance is strongly affected by their structural conformation including both electrical and optical anisotropy. Particularly for thin layers or close to crucial interfaces, there are few methods to track their organization and functional behaviors. Here we present a platform based on plasmonic nanogaps that can assess the chemical structure and orientation of conjugated polymers down to sub-10 nm thickness using light. We focus on a representative conjugated polymer, poly(3,4-ethylenedioxythiophene) (PEDOT), of varying thickness (2-20 nm) while it undergoes redox in situ. This allows dynamic switching of the plasmonic gap spacer through a metal-insulator transition. Both dark-field (DF) and surface-enhanced Raman scattering (SERS) spectra track the optical anisotropy and orientation of polymer chains close to a metallic interface. Moreover, we demonstrate how this influences both optical and redox switching for nanothick PEDOT devices.

关键词： transition insulator conjugated

Bone morphogenetic protein 2-induced human dental pulp cell differentiation involves p38 mitogen-activated protein kinase-activated canonical WNT pathway

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International Journal of Oral Science 2015年第2期7卷 95-102页

作者： Jing Yang ling Ye Tian-Qian Hui Dong-Mei Yang Ding-Ming Huang Xue-Dong Zhou jeremy J Mao Cheng-lin Wang State Key Laboratory of Oral Diseases West China Hospital of StomatologySichuan University Center for Craniofacial Regeneration(CCR) Columbia University Medical Center

Both bone morphogenetic protein 2（BMP2） and the wingless-type MMTV integration site（WNT）/p-catenin signalling pathway play important roles in odontoblast differentiation and ***-talk between BMP2 and WNT/p-catenin in osteoblast differentiation and bone formation has been ***,the roles and mechanisms of the canonical WNT pathway in the regulation of BMP2 in dental pulp injury and repair remain largely ***,we demonstrate that BMP2 promotes the differentiation of human dental pulp cells（HDPCs） by activating WNT/p-catenin signalling,which is further mediated by p38mitogen-activated protein kinase（MAPK） in ***2 stimulation upregulated the expression of p-catenin in HDPCs,which was abolished by SB203580 but not by Noggin or ***,BMP2 enhanced cell differentiation,which was not fully inhibited by Noggin or ***,SB203580 partially blocked BMP2-induced p-catenin expression and cell *** together,these data suggest a possible mechanism by which the elevation of p-catenin resulting from BMP2 stimulation is mediated by the p38 MAPK pathway,which sheds light on the molecular mechanisms of BMP2-mediated pulp reparative dentin formation.

关键词： dental catenin morphogenetic stimulation canonical inhibited blocked repair activating mitogen

Move a Tropical Cyclone with 4D-Var and Vortex Dynamical Initialization in WRF Model

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Journal of Tropical Meteorology 2021年第3期27卷 191-200页

作者： WANG Ting PENG Yue-hua ZHANG Bang-lin LEUNG jeremy Cheuk-Hin SHI Wei-lai Mail Box 5111 Beijing 100094 China Dalian Naval Academy DalianLiaoning 116018 China Institute of Atmospheric Physics Chinese Academy of SciencesBeijing 100029 China Guangzhou Institute of Tropical and Marine Meteorology/Guangdong Provincial Key Laboratory of Regional Numerical Weather Prediction China Meteorological AdministrationGuangzhou 510000 China College of Meteorology and Oceanography National University of Defense TechnologyChangsha 410073 China

Previous studies showed that 4 D-Var technique used for data assimilation could be modified for weather control. This study demonstrates the ability of 4 D-Var to influence the future path of a tropical cyclone by calculating perturbations in WRF simulation. Given the background error covariance matrix, the initial field is improved by the vortex dynamic initialization technique. Our results show that 4 D-Var can be applied to control the trajectory of simulated tropical cyclones by producing "optimal" perturbations. In the numerical simulation experiment of Typhoon Mitag in 2019, after this kind of weather control similar to data assimilation, the tropical cyclone moved obviously,and the damaging wind over the coastline weakened. The prediction results after the initial field modified by 4 D-Var have a great change, and the position of the tropical cyclone moved about 0.5° southeastward after assimilation,which misses the southeast coast of China. Moreover, the damaging wind is also weakened. Since the 4 D-Var is premised on the assumption that the model is perfect and does not consider the model error, then the research plan to consider model error and introduce new methods is discussed in the paper.

关键词： 4D-Var weather control Typhoon Mitag WRF model vortex dynamical initialization

Quantitative interactomic of CD40 in primary B cells

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hLife 2024年第2期2卷 88-93页

作者： jeremy Argenty Emilie Maturin Mylene Camus Valentin Mellado Jeanne Perroteau Benoit Pasquier Guillaume Voisinne Odile Burlet-Schiltz Lih-ling lin Anne Gonzalez de Peredo Romain Roncagalli Bernard Malissen Centre d’Immunologie de Marseille-Luminy Aix Marseille UniversitéINSERMCNRSMarseilleFrance Centre d’Immunophénomique Aix Marseille UniversitéINSERMCNRS UMRMarseilleFrance Institut de Pharmacologie et de Biologie Structurale Département Biologie Structurale BiophysiqueProtéomique Génopole Toulouse Midi Pyrénées CNRS UMR 5089205 Route de NarbonneToulouse CedexFrance Checkpoint Immunology Immunology and Inflammation Therapeutic AreaSanofiVitryFrance Checkpoint Immunology Immunology and Inflammation Therapeutic AreaSanofiCambridgeUSA

INTRODUCTION Over the past few decades,antibody-based therapies have emerged as an additional tool to treat patients developing cancer and auto-immune *** natural properties of the developed antibodies may lead to agonist or blocking functions for the targeted ***,antibodies developed for clinical trials are extensively analyzed in vitro and in vivo for safety and efficacy,yet they are not routinely evaluated for their potential signaling effectiveness.

关键词： routine antibodies clinical

The novel male meiosis recombination regulator coordinates the progression of meiosis prophase Ⅰ

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Journal of Genetics and Genomics 2020年第8期47卷 449-464页

作者： Miao Li Haiwei Feng Zexiong lin Jiahuan Zheng Dongteng Liu Rui Guo Junshi Li Raymond H.W.Li Ernest H.Y.Ng Michael S.Y.Huen P.jeremy Wang William S.B.Yeung Kui Liu Shenzhen Key Laboratory of Fertility Regulation Center of Assisted Reproduction and EmbryologyThe University of Hong Kong-Shenzhen HospitalShenzhen518000China Department of Obstetrics and Gynecology Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong999077China Department of Biomedical Sciences University of Pennsylvania School of Veterinary MedicinePhiladelphiaPA19104USA School of Biomedical Sciences Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong999077China

Meiosis is a specialized cell division for producing haploid gametes in sexually reproducing *** this study,we have independently identified a novel meiosis protein male meiosis recombination regulator(MAMERR)/4930432 K21 Rik and showed that it is indispensable for meiosis prophase I progression in male *** super-resolution structured illumination microscopy,we found that MAMERR functions at the same double-strand breaks as the replication protein A and meiosis-specific with OB domains/spermatogenesis associated 22 *** generated a Mamerr-deficient mouse model by deleting exons 3 e6 and found that most of Mamerrà/àspermatocytes were arrested at pachynema and failed to progress to diplonema,although they exhibited almost intact synapsis and progression to the pachytene stage along with XY body *** mechanistic studies revealed that the recruitment of DMC1/RAD51 and heat shock factor 2 ebinding protein in Mamerrà/àspermatocytes was only mildly impaired with a partial reduction in double-strand break repair,whereas a substantial reduction in ubiquitination on the autosomal axes and on the XY body appeared as a major phenotype in Mamerrà/à*** propose that MAMERR may participate in meiotic prophase I progression by regulating the ubiquitination of key meiotic proteins on autosomes and XY chromosomes,and in the absence of MAMERR,the repressed ubiquitination of key meiotic proteins leads to pachytene arrest and cell death.

关键词： Meiosis 4930432K21Rik Recombination Ubiquitination

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带间级联激光器性能对结构变化的耐受性研究

红外与毫米波学报 2020年第2期39卷 137-141页

作者：林羽喆 jeremy A.Massengale 黄文祥杨瑞青 Tetsuya D.Mishima Michael B.Santos 中国科学院半导体研究所固态光电信息实验室北京100083 俄克拉荷马大学电子与计算机工程系美国诺曼73019 中国科学院大学材料科学与光电工程中心北京100049 俄克拉荷马大学物理与天文学系美国诺曼73019

通过对两种结构参数与设计偏差较大的带间级联激光器(ICL)的研究,探讨了器件性能在结构变化下的耐受性。在300 K时,即使和4.6μm的设计波长相比蓝移700μm以上,激光器仍然性能良好,其阈值电流密度低至320 A/cm^2。此研究为带间级联激光... 详细信息

通过对两种结构参数与设计偏差较大的带间级联激光器(ICL)的研究,探讨了器件性能在结构变化下的耐受性。在300 K时,即使和4.6μm的设计波长相比蓝移700μm以上,激光器仍然性能良好,其阈值电流密度低至320 A/cm^2。此研究为带间级联激光器在结构变化方面的耐受性提供了坚实的实验依据。

关键词： Ⅲ-Ⅴ族半导体带间级联激光器中红外量子阱 Ⅱ类异质结

Factors influencing communication of traditional Chinese medicine use between patients and doctors:A multisite cross-sectional study

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Journal of Integrative Medicine 2019年第6期17卷 396-403页

作者： Wen Qiang Lee jeremy Teoh Pei Zheng Kenneth Lee Zhi Xiong Gerard Low Xueling Sim Foong Fong Mary Chong Norbert Ludwig Wagner Yong Loo lin School of Medicine National University of Singapore117597Singapore Saw Swee Hock School of Public Health National University of Singapore117549Singapore

Objective: In Singapore, the use of traditional Chinese medicine(TCM) alongside Western medicine(WM)is common. There are risks of adverse herb-drug interactions when taken concurrently. Current literature suggests that TCM use is not regularly reported to WM doctors in Singapore, but the underlying reasons are not ***: A cross-sectional study was conducted across Singapore by administering questionnaires to TCM-using patients and WM-practising general practitioners(GPs). The questionnaire examined the following themes:(1) demographics and TCM use pattern;(2) respondents'(patients and GPs) knowledge and beliefs about TCM and the factors influencing the discussion of TCM during the WM consultation;and(3) respondents' qualitative suggestions to increase disclosure ***: A total of 484 patients and 334 GPs were surveyed. Factors associated with patients' initiation of TCM discussion include length of consultation(odds ratio [OR]: 2.1;P < 0.001), comfort level in discussing TCM(OR: 1.6;P < 0.001) and belief in importance of discussion(OR: 1.4;P = 0.017). Doctor's initiation of discussion(74%) was the top patient-ranked factor influencing their discussion of TCM. For doctors,knowledge of TCM indications(OR: 2.2;P < 0.001), belief in importance of discussion(OR: 2.1;P < 0.001) and comfort level in discussing TCM(OR: 1.9;P = 0.001) were associated with their initiation of TCM use discussion. Possible WM-TCM interactions(58%) was the top doctor-ranked factor influencing their discussion of ***: The discussion of TCM in a WM setting is multifactorial. Interventions include doctors' active screening for TCM use in patients and equipping doctors with TCM knowledge. Improving communication between patients and doctors is key to avoiding harmful herb-drug interactions.

关键词： Traditional Chinese medicine Western medicine Patient-provider communication Primary care General practice Public health