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Cellular & Molecular Immunology 2020年第6期17卷 662-664页

作者： Yong-Chan Kim Min-ju jeong Byung-Hoon jeong Korea Zoonosis Research Institute Chonbuk National UniversityIksanJeonbuk 54531Republic of Korea Department of Bioactive Material Sciences Chonbuk National UniversityJeonjuJeonbuk 54896Republic of Korea

The IFITM3 gene is classified as a member of the small interferonstimulated genes(ISGs)and plays a paramount role in defense against enveloped viruses,including influenza A viruses.1–6 Previous studies have reported that the rs12252 SNP,which is located in the open reading frame(ORF)of the IFITM3 gene,impacts the splicing procedure of protein production,which makes a truncated form of the IFITM3 protein and lowers its antiviral capacity.7–9 In addition,the rs34481144 SNP genotype affects the transcriptional regulation of the IFITM3 gene and IFITM3-neighboring genes and has a potent association with the clinical results of the H1N1 influenza 2009 pandemic in three human cohorts.10 Because several studies have reported that polymorphism of the IFITM3 gene is crucial in the host immune response,fine mapping of and extracting disease-associated SNPs from the human IFITM3 gene are important baseline studies necessary to understand how the IFITM3 protein functions in innate immunity.

关键词： IFITM3 influenza H1N1

Application of Integrated Database to the Casting Design

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Journal of Materials Science & Technology 2008年第3期24卷 351-355页

作者： In-Sung Cho Seung-Mok yoo Chae-Ho Lim jeong-Kil Choi KITECH 7-47 Songdo-dongYeonsu-gu

Construction of integrated database including casting shapes with their casting design, technical knowledge, and thermophysical properties of the casting alloys were introduced in the present study. Recognition tech- nique for casting design by industrial computer tomography was used for the construction of shape database. Technical knowledge of the casting processes such as ferrous and non-ferrous alloys and their manufacturing process of the castings were accumulated and the search engine for the knowledge was developed. Database of thermophysical properties of the casting alloys were obtained via the experimental study, and the properties were used for the in-house computer simulation of casting process. The databases were linked with intelligent casting expert system developed in center for e-design, KITECH. It is expected that the databases can help non casting experts to devise the casting and its process. Various examples of the application by using the databases were shown in the present study.

关键词： Integrated database Casting design Shape recognition

Proton therapy for hepatocellular carcinoma:Current knowledges and future perspectives

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World Journal of Gastroenterology 2018年第28期24卷 3090-3100页

作者： Gyu Sang yoo jeong Il Yu Hee Chul Park Department of Radiation Oncology Samsung Medical Center Sungkyunkwan University School of Medicine Department of Medical Device Management and Research Samsung Advanced Institute for Health Sciences and Technology Sungkyunkwan University

Hepatocellular carcinoma(HCC) is the second leading cause of cancer-related death, as few patients can be treated with currently available curative local modalities. In patients with HCC where curative modalities are not feasible, radiation therapy(RT) has emerged as an alternative or combination therapy. With the development of various technologies, RT has been increasingly used for the management of HCC. Among these advances, proton beam therapy(PBT) has several unique physical properties that give it a finite range in a distal direction, and thus no exit dose along the beam path. Therefore, PBT has dosimetric advantages compared with X-ray therapy for the treatment of HCC. Indeed, various reports in the literature have described the favorable clinical outcomes and improved safety of PBT for HCC patients compared with X-ray therapy. However, there are some technical issues regarding the use of PBT in HCC, including uncertainty of organ motion and inaccuracy during calculation of tissue density and beam range, all of which may reduce the robustness of a PBT treatment plan. In this review, we discuss the physical properties, current clinical data, technical issues, and future perspectives on PBT for the treatment of HCC.

关键词： radiation therapy hepatocellular carcinoma proton beam therapy X-ray therapy

Unveiling anomalous lattice shrinkage induced by Pi-backbonding in Prussian blue analogues

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Journal of Energy Chemistry 2022年第7期31卷 121-128,I0004页

作者： ju-Hyeon Lee Jin-Gyu Bae Hyeon jeong Lee Ji Hoon Lee School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566Republic of Korea Department of Materials University of OxfordOxford OX13PHUnited Kingdom

Transition-metal(TM)-based Prussian blue and its analogues(TM-PBAs) have attracted considerable attention as cathode materials owing to their versatile ion storage capability with tunable working voltages. TM-PBAs with different crystal structures, morphologies, and TM combinations can exhibit excellent electrochemical properties because of their unique and robust host frameworks with well-defined ionic diffusion channels. Nonetheless, there is still a lack of understanding regarding the performance dependence of TM-PBAs on structural changes during charging/discharging processes. In this study, in situ X-ray diffraction and X-ray absorption fine structure analyses elucidate the TMdependent structural changes in a series of TM-PBAs during the charging and discharging *** the discharging process, the lattice volume of Fe-PBA increased while those of Ni-and Cu-PBAs decreased. This discrepancy is attributed to the extent of size reduction of the cyanometallate complex([Fe(CN)_(6)]) via pi-backbonding from Fe to C due to redox flips of the low-spin Fe^(3+/2+) ion. This study presents a comprehensive understanding of how TM selection affects capacity acquisition and phase transition in TM-PBAs, a promising class of cathode materials.

关键词： Prussian blue analogues X-ray diffraction X-ray absorption fine structure Pi-backdonation Cyanides

Machine learning for CO_(2) capture and conversion:A review

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Energy and AI 2024年第2期16卷 512-527页

作者： Sung Eun Jerng Yang jeong Park ju Li Department of Environmental and Energy Engineering The University of Suwon17Wauan-gilBongdam-eupHwaseong-si18323Gyeonggi-doRepublic of Korea Department of Materials Science and Engineering Massachusetts Institute of Technology77 Massachusetts AveCambridge02139MAUnited States of America Department of Nuclear Science and Engineering Massachusetts Institute of Technology77 Massachusetts AveCambridge02139MAUnited States of America MIT-IBM Watson AI Lab 75 Binney StreetCambridge02142MAUnited States of America

Coupled electrochemical systems for the direct capture and conversion of CO have garnered significant attention owing to their potential to enhance energy-and cost-efficiency by circumventing the amine regeneration ***,optimizing the coupled system is more challenging than handling separated systems because of its complexity,caused by the incorporation of solvent and heterogeneous ***,the deployment of machine learning can be immensely beneficial,reducing both time and cost owing to its ability to simulate and describe complex systems with numerous parameters *** this review,we summarized the machine learning techniques employed in the development of CO_(2)capture solvents such as amine and ionic liquids,as well as electrochemical CO_(2)conversion *** optimize a coupled electrochemical system,these two separately developed systems will need to be combined via machine learning techniques in the future.

关键词： Machine learning CO_(2)conversion CO_(2)capture Amine Ionic liquids Single-atom alloys High-entropy catalysts

Physiological and Biochemical Modulations upon Root Induction in Rose Cuttings as Affected by Growing Medium

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Horticultural Plant Journal 2018年第6期4卷 257-264页

作者： KIM Soohoon ABINAYA Manivannan PARK yoo Gyeong jeong Byoung Ryong Division of Applied Life Science (BK21 Plus Program) Graduate School Gyeongsang National University Institute of Agriculture and Life Science Gyeongsang National University Research Institute of Life Science Gyeongsang National University

Two cut rose(Rosa hybrida) cultivars ‘Sherbet'(easy-to-root) and ‘Alibaba'(difficult-to-root) were propagated by single nodal cuttings on preformed media. Four commercial media such as Tosilee, Ellepot, rockwool and phenolic foam RC, and four newly-developed foam media namely Oasis PU 14-S1, Oasis TP-S1, Oasis PU-7 B and Oasis PU 15-S1 were employed in this study. All media were manufactured to fit into50-cell plug trays. The experiment was laid out in a complete randomized block design with three replications on a propagation bench with a plastic tunnel installed in a glasshouse, with(98 ± 2)% relative humidity and over 50% shading of the natural sunlight. After four weeks of experiment, growth parameters, localization of superoxide radicals, and activities of rooting biochemical markers were measured. The results suggested that the newly-developed foam media Oasis TP-S1 and Oasis PU-7 B enhanced the growth, density of leaf stomata, and consisted of lesser harmful superoxide radicals in similar manner with the existing commercial media. Moreover, the Oasis TP-S1 and Oasis PU-7 B media significantly enhanced the total phenol content and the activities of important enzymes involved in the phenol metabolism which plays a vital role in the formation of roots. Thus, the understanding of both physiological and biochemical changes implicated by the growing medium during the rooting of cuttings would aid in the selection of optimal growing medium for the propagation of rose cuttings.

关键词： foam medium peroxidase phenol phenylalanine ammonia lyase(PAL) superoxide localization

Abnormal Behavior Detection Using Deep-Learning-Based Video Data Structuring

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Intelligent Automation & Soft Computing 2023年第8期37卷 2371-2386页

作者： Min-jeong Kim Byeong-Uk Jeon Hyun yoo Kyungyong Chung Department of Computer Science Kyonggi UniversitySuwon-si16227Gyeonggi-doKorea Contents Convergence Software Research Institute Kyonggi UniversitySuwon-si16227Gyeonggi-doKorea Division of AI Computer Science and Engineering Kyonggi UniversitySuwon-si16227Gyeonggi-doKorea

With the increasing number of digital devices generating a vast amount of video data,the recognition of abnormal image patterns has become more ***,it is necessary to develop a method that achieves this task using object and behavior information within video *** methods for detecting abnormal behaviors only focus on simple motions,therefore they cannot determine the overall behavior occurring throughout a *** this study,an abnormal behavior detection method that uses deep learning(DL)-based video-data structuring is *** and motions are first extracted from continuous images by combining existing DL-based image analysis *** weight of the continuous data pattern is then analyzed through data structuring to classify the overall *** performance of the proposed method was evaluated using varying parameter settings,such as the size of the action clip and interval between action *** model achieved an accuracy of 0.9817,indicating excellent ***,we conclude that the proposed data structuring method is useful in detecting and classifying abnormal behaviors.

关键词： Deep learning object detection abnormal behavior recognition classification data structuring

Unusual presentation of granulomatosis with polyangiitis causing periaortitis and consequent subclavian steal syndrome:A case report

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World Journal of Clinical Cases 2021年第6期9卷 1433-1438页

作者： Uiju Cho Sung-Kyung Kim jeong Min Ko Jinyoung yoo Department of Pathology St.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Internal Medicine St.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Radiology St.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Hospital Pathology St.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea

BACKGROUND Granulomatosis with polyangiitis(GPA)is a rare autoimmune disease that involves small-to-medium-sized vessels and forms necrotizing vasculitis with granulomatous *** formation of a large vessel lesion in GPA patients has been scarcely reported,and it can cause confusion in the *** SUMMARY A 27-year-old man presented with mild left-sided pleuritic chest pain that started one year *** imaging study revealed up to 2.5 cm-sized two irregular nodular consolidation nodule in the left lower *** nodules showed central ***,there was a periaortic mass occluding the branching porting of the subclavian *** had positive anti-neutrophil cytoplasmic antibodies(ANCAs),but myeloperoxidase-ANCAs and proteinase 3-ANCAs were *** patient also developed symptoms of subclavian vein syndrome during the *** resection of the lung revealed necrotizing vasculitis,destructive parenchymal abscess and surrounding granuloma,and therefore diagnosed of *** patient started on methotrexate and steroid therapy with a relief of *** Here,we present an unusual manifestation of GPA with periaortitis and consequent subclavian steal syndrome,which has never been previously *** case alerts us that we should include GPA in the differential diagnosis of large vessel vasculitis as well as subclavian steal syndrome.

关键词： Granulomatosis with polyangiitides Wegener granulomatosis Systemic vasculitis Subclavian steal syndrome Periaortitis Case report

Combined Insights from Leachate Structure and Microstructure Characteristics for Eating Quality of Convenience Rice Processed by Super-Heated and Pressurized Steam Technologies

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Rice science 2024年第4期31卷 475-488,I0035,I0036页

作者： Mingyo HA Hyo-Young jeong ju Hun LEE Hyun-jung CHUNG Division of Food and Nutrition Chonnam National UniversityGwangju 61186South Korea Department of Biotechnology College of Life Sciences and BiotechnologyKorea UniversitySeoul 02841South Korea Division of Food Science&Culinary Arts Shinhan UniversityGyeonggi 11644South Korea

Convenience rice has become widely popular due to its easy availability for cooking. This study investigated the starch structure and composition of leachate and the microstructure of reheated convenience rice using novel processing technologies: super-heated steaming(SHS), auto-electric cooking(AEC), and pressurized-steam cooking(PSC). Additionally, the effect of two different target water contents(58% and 63%) was also evaluated. The PSC_63% sample had the highest total solids and amylopectin amount in the leachate. The amylopectin amount in the leachate differed significantly based on the targeted water content. Morphological characterization revealed that the swelling of starch and the coated layer on the surface of rice grains were most pronounced in the PSC_63% sample due to the pressure processing. The textural hardness of the AEC_58% sample was much higher than that of the other samples. The PSC_63% sample had the highest textural adhesiveness value, which can be attributed to the highest amylopectin amount in the leachate. Sensory characterization showed that the PSC_63% sample had the highest glossiness, whiteness, moistness, and overall acceptability. The principal component analysis score plots presented substantial differences in the leachate and textural and sensory characteristics of reheated convenience rice among the different processing technologies.

关键词： reheated convenience rice starch structure leachate multi-scale structure eating quality processing technology

Preparation and characterization of solidified SMEDDS containing flurbiprofen by spray drying method

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Asian Journal of Pharmaceutical Sciences 2016年第1期11卷 108-109页

作者： yoo-jeong Jang Kwan Hyung Cho College of Pharmacy Inje University

Flurbiprofen, a non-steroidal anti-inflammatory agent, is used to treat rheumatoid arthritis and sore throat (1)However, it gave poor water solubility, and various solubilization technique such as self-microemulsifying drug delivery system(SMEDDS) has been used to improve the solubility, dissolution and oral bioavailability [2].The objective of this work was to develop redispersible solidified SMEDDS containing water-insoluble flurbiprofen with enhanced solubility.

关键词： Flurbiprofen Solidified SMEDDS Solubilization