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Effects of dietary supplementation of bacteriophage cocktail on health status of weanling pigs in a non-sanitary environment

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Journal of Animal Science and Biotechnology 2023年第4期14卷 1661-1677页

作者： YoHan Choi Abdolreza Hosseindoust Sang hun Ha Joeun Kim YeJin Min YongDae jeong JunYoung Mun SooJin Sa JinSoo Kim Swine Science Division National Institute of Animal ScienceRural Development AdministrationCheonan 31000Republic of Korea Department of Animal Industry Convergence Kangwon National UniversityChuncheon 24341Republic of Korea

Background The study evaluated the effects of bacteriophage cocktail(BP)and ZnO administered during weaning time for piglets exposed to a non-sanitary *** bacteriophages were designed to eliminate Escherichia coli(K88,K99 and F41),Salmonella(typhimurium and enteritidis),and Clostridium perfreingens(types A and C).Forty 21-day-old crossbreed piglets were assigned to four treatments,including the PC(sanitary environment),NC(nonsanitary environment),BP(NC plus 108 pfu/kg BP),and ZO(NC plus 2,500 mg/kg ZnO).Piglets in the NC,BP and ZO were kept in a non-sanitary environment for 14 d,which was contaminated with the feces of infected *** Pigs in the BP and ZO treatments had a higher final body weight compared with the *** NC treatment showed the highest concentration of inflammatory cytokines including interleukin(IL)-1β,IL-6 and tumor necrosis factor-αin the *** administration of BP and ZO showed lower myeloperoxidase concentrations compared with the *** NC treatment showed a lower concentration of superoxide dismutase in serum compared with the *** the treatments in non-sanitary environment,the NC treatment showed a higher concentration of malondialdehyde compared with the *** PC treatment showed a lower concentration of butyric acid in the feces compared with the BP *** non-sanitary treatments,the villus height in the duodenum was greater in the BP and ZO compared with the *** lower abundance of Proteobacteria phylum was observed in the BP and PC treatments compared with the *** highest relative abundance of Eubacterium was recorded in the BP *** abundance of Megasphaera and Schwartzia was higher in the NC pigs compared with the BP *** abundance of Desulfovibrio was lower in the supplemented treatments(BP and ZO)compared with non-supplemented(NC and PC).The abundance of Cellulosilyticum genera was higher in the BP and ZO treatments rather than in the *** piglets in the NC treatment had the

关键词： Antioxidant Cytokines Diarrhea Fecal score Inflammation Microbiota Proteobacteria

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Proxy-Based Hierarchical Distributed Mobility Management for Tactical Networks

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Computers, Materials & Continua 2022年第2期70卷 2381-2399页

作者： Myoung-hun Han Bong-Soo Roh Kyungwoo Kim Dae-Hoon Kwon Jae-hyun Ham Kyunghyun Yoon Sanghyun Seo Agency for Defense Development Daejeon34186Korea Department of Computer Science and Engineering Chung-Ang UniversitySeoul06974Korea College of Art&Technology Chung-Ang UniversityAnseong17546Korea

An important requirement in a military domain is a highly reliable mobility management method,especially when components of the networks aremoving in tactical network *** increase reliability,themobility management technology of the tactical network should be able to reflect the characteristics of the tactical network,such as a limited environment,failure,and hierarchical unit *** this paper,we propose a proxy-based hierarchical distributedmobilitymanagement scheme,which is highly focused on tactical *** the characteristics of tactical networks,the proposed scheme is composed of the following:1)a proxy-based method,2)a distributed mobility management method that synchronizes a mobility database between entities,and 3)a method of managing mobility by dividing the tactical network into upper and lower *** analysis and modeling and simulation results demonstrate that the method outperforms the existing state-of-the-art method in overcoming entity failure,handover cost,and delay in tactical environments.

关键词： Mobility management tactical networks PMIP DMM

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Precise control of surface oxygen vacancies in ZnO nanoparticles for extremely high acetone sensing response

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Journal of Advanced Ceramics 2022年第5期11卷 769-783页

作者： Jihyun LEE Youngmoon CHOI Byoung Joon PARK jeong Woo HAN hyun-Sook LEE Jong Hyeok PARK Wooyoung LEE Department of Materials Science and Engineering Yonsei UniversitySeoul 03722Republic of Korea Department of Chemical and Biological Engineering Yonsei UniversitySeoul 03722Republic of Korea Department of Chemical Engineering Pohang University of Science and TechnologyPohang 37673Republic of Korea Institute for Convergence Research and Education in Advanced Technology Yonsei UniversitySeoul 03722Republic of Korea

ZnO has been studied intensely for chemical sensors due to its high sensitivity and fast ***,we present a simple approach to precisely control oxygen vacancy contents to provide significantly enhanced acetone sensing performance of commercial ZnO nanopowders.A combination of H_(2)O_(2)treatment and thermal annealing produces optimal surface defects with oxygen vacancies on the ZnO nanoparticles(NPs).The highest response of~27,562 was achieved for 10 ppm acetone in 0.125 MH_(2)O_(2)treated/annealed ZnO NPs at the optimal working temperature of 400℃,which is significantly higher than that of reported so far in various acetone sensors based on metal oxide semiconductors(MOSs).Furthermore,first-principles calculations indicate that pre-adsorbed O formed on the surface of H_(2)O_(2)treated ZnO NPs can provide favorable adsorption energy,especially for acetone detection,due to strong bidentate bonding between carbonyl C atom of acetone molecules and pre-adsorbed O on the ZnO *** study demonstrates that controlling surface oxygen vacancies by H_(2)O_(2)treatment and re-annealing at optimal temperature is an effective method to improve the sensing properties of commercial MOS materials.

关键词： gas sensors acetone metal oxide semiconductors(MOSs) ZnO nanoparticles(NPs) H_(2)O_(2)treatment

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Corrugated surface microparticles with chitosan and levofloxacin for improved aerodynamic performance

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Asian Journal of Pharmaceutical Sciences 2023年第3期18卷 146-158页

作者： Chang-Soo Han Ji-hyun Kang Eun hye Park Hyo-Jung Lee So-jeong jeong Dong-Wook Kim Chun-Woong Park College of Pharmacy Chungbuk National UniversityCheongju 28160Republic of Korea School of Pharmacy Jeonbuk National UniversityJeonju 54896Republic of Korea College of Pharmacy Wonkwang UniversityIksan 54538Republic of Korea

Corrugated surface microparticles comprising levofloxacin(LEV),chitosan and organic acid were prepared using the 3-combo spray drying *** amount and the boiling point of the organic acid affected the degree of *** this study,we tried to improve the aerodynamic performance and increase aerosolization by corrugated surface microparticle for lung drug delivery efficiency as dry powder ***175 L20 prepared with 175 mmol propionic acid solution was corrugated more than HMF175 L20 prepared with 175 mmol formic acid *** ACI and PIV results showed a significant increase in aerodynamic performance of corrugated *** FPF value of HMP175 L20 was 41.3%±3.9%compared with 25.6%±7.7%of HMF175 *** microparticles also showed better aerosolization,decreased x-axial velocity,and variable *** dissolution of drug formulationswas observed in *** administered to the lungs achieved higher LEV concentrations in the lung fluid than high doses administered *** modification in the polymer-based formulation was achieved by controlling the evaporation rate and improving the inhalation efficiency of DPIs.

关键词： Chitosan Organic acid Levofloxacin Corrugated surface Aerodynamic performance

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Point-defect engineering of nanoporous CuBi_(2)O_(4) photocathode via rapid thermal processing for enhanced photoelectrochemical activity

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Journal of Energy Chemistry 2022年第8期31卷 201-209,I0007页

作者： Li Qu Runfa Tan Arumugam Sivanantham Min Je Kang Yoo Jae jeong Dong hyun Seo Sungkyu Kim In Sun Cho Department of Materials Science&Engineering Ajou UniversitySuwon 16499South Korea Department of Energy Systems Research Ajou UniversitySuwon 16499South Korea Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006South Korea

Engineering point defects such as metal and oxygen vacancies play a crucial role in manipulating the electrical,optical,and catalytic properties of oxide semiconductors for solar water ***,we synthesized nanoporous CuBi_(2)O_(4)(np-CBO)photocathodes and engineered their surface point defects via rapid thermal processing(RTP)in controlled atmospheres(O_(2),N_(2),and vacuum).We found that the O_(2)-RTP treatment of np-CBO increased the charge carrier density effectively without hampering the nanoporous morphology,which was attributed to the formation of copper vacancies(VCu).Further analyses revealed that the amounts of oxygen vacancies(Vo)and Cu^(1+)were reduced simultaneously,and the relative electrochemical active surface area increased after the O_(2)-RTP ***,the point defects(VC_(u),Cu^(1+),and Vo)regulated np-CBO achieved a superb water-splitting photocurrent density of-1.81 m A cm^(-2) under simulated sunlight illumination,which is attributed to the enhanced charge transport and transfer properties resulting from the regulated surface point ***,the reversibility of the formation of the point defects was checked by sequential RTP treatments(O_(2)-N_(2)-O_(2)-N_(2)),demonstrating the strong dependence of photocurrent response on the RTP ***,the surface point defect engineering via RTP treatment in a controlled atmosphere is a rapid and facile strategy to promote charge transport and transfer properties of photoelectrodes for efficient solar water-splitting.

关键词： Nanoporous Copper bismuth oxide Rapid thermal processing Copper vacancy Charge transport

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Study on the Relationship between Mental Health Literacy and Psychological Symptoms of University Students: Mediating Effect of Grit

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International Journal of Mental Health Promotion 2023年第7期25卷 813-821页

作者： Yeo-Won jeong Jung-Ha Kim hyun-Kyeong Park Department of Nursing College of Nursing Dongguk UniversityGyeongju-si38066Korea Aeromedical Center of Korean Air Seoul07505Korea Department of Nursing Graduate SchoolDongguk UniversityGyeongju-si38066Korea

Background:The occurrence of mental health symptoms is higher in individuals aged between 18 and 24 years than in other age *** health literacy is derived from health literacy,and focuses on the knowledge,attitudes,and competencies that individuals need to acquire to manage their own health *** mental health literacy is associated with poorer mental *** is also a known protective factor against mental *** a heightened focus on mental health literacy and grit as important factors for decreasing mental health symptoms,knowledge of the effect of mental health literacy and grit on mental health symptoms is very *** study aimed to evaluate the relationship between mental health literacy and psychological symptoms and the mediating effect of grit on these ***:This cross-sectional descriptive study used survey data from 178 university students in *** were collected between March and May *** SPSS PROCESS macro(Model 4)was used to analyze the ***:Mental health literacy was not directly associated with psychological ***,an indirect pathway was observed between mental health literacy,depression,and anxiety,through ***:Mental health literacy affects psychological symptoms through ***,to improve the mental health of university students,it is necessary to develop programs that increase mental health literacy and grit.

关键词： Depression anxiety psychological stress health literacy mental health students

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Association between Occupational Change Trajectories and Mental Health: Results from the Korean Longitudinal Study of Aging

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International Journal of Mental Health Promotion 2023年第4期25卷 579-594页

作者： jeong Min Yang Hyeon Ji Lee Jae hyun Kim Institute for Digital Life Convergence Dankook UniversityCheonan31116South Korea Department of Public Health General Graduate School of Dankook UniversityCheonan31116South Korea Department of Health Administration College of Health ScienceDankook UniversityCheonan31116South Korea

Objectives:This study was to longitudinally investigate the association between occupational change trajectories and mental health in the Korean population aged 45 years and older from the Korean Longitudinal Study of Aging(KLo-SA).Methods:After excluding missing values,the data of 6,224 participants from thefirst to eighth waves of the KLo-SA were analyzed using t-test,Analysis of variance(ANOVA),Group-based Trajectory Model(GBTM)from 1–5th KLoSA and Time-Lagged Generalized estimating equation(GEE)model from 5–8th KLoSA to analyze the association between occupational change trajectories and mental health in the Korean population aged 45 years and ***:An analysis of the association between occupational change trajectories and mental health demonstrated that,among all age group,the“sustained in unemployment”group had a worse MMSE and CESD score compared to“sustained WC”*** the under-54 age group,those aged≥55 years demonstrated reductions in the MMSE and CESD scores in the sustained unemployment and the changed working condition from Standard BC to Unemployment groups,whereas those who underwent a change from the Standard WC to unemployment group only demonstrated a reduction in MMSE ***:There was a close relationship between occupational change trajectories and mental ***,this study can serve as the foundation for policies and institutional measures to manage the deteriorate mental health in the late middle-aged and older population.

关键词： CESD change in job employment status mental health MMSE trajectory

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Brassinosteroids enhance salicylic acid-mediated immune responses by inhibiting BIN2 phosphorylation of clade I TGA transcription factors in Arabidopsis

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Molecular Plant 2022年第6期15卷 991-1007页

作者： Yeong-Woo Kim Ji-hyun Youn Jeehee Roh jeong-Mok Kim Seong-Ki Kim Tae-Wuk Kim Department of Life Science Hanyang UniversitySeoul 04763Republic of Korea Department of Life Science Chung-Ang UniversitySeoul 06973Republic of Korea Research Institute for Convergence of Basic Science Hanyang UniversitySeoul 04763Republic of Korea Hanyang Institute of Bioscience and Biotechnology Hanyang UniversitySeoul 04763Republic of Korea

Salicylic acid (SA) plays an important role in plant immune response, including resistance to pathogens and systemic acquired resistance. Two major components, NONEXPRESSOR OF PATHOGENESIS-RELATED GENES (NPRs) and TGACG motif-binding transcription factors (TGAs), are known to mediate SA signaling, which might also be orchestrated by other hormonal and environmental changes. Nevertheless, the molecular and functional interactions between SA signaling components and other cellular signaling pathways remain poorly understood. Here we showed that the steroid plant hormone brassinosteroid (BR) promotes SA responses by inactivating BR-INSENSITIVE 2 (BIN2), which inhibits the redox-sensitive clade I TGAs in Arabidopsis. We found that both BR and the BIN2 inhibitor bikinin synergistically increase SA-mediated physiological responses, such as resistance to Pst DC3000. Our genetic and biochemical analyses indicated that BIN2 functionally interacts with TGA1 and TGA4, but not with other TGAs. We further demonstrated that BIN2 phosphorylates Ser-202 of TGA4, resulting in the suppression of the redox-dependent interaction between TGA4 and NPR1 as well as destabilization of TGA4. Consistently, transgenic Arabidopsis overexpressing TGA4-YFP with a S202A mutation displayed enhanced SA responses compared to the wild-type TGA4-YFP plants. Taken together, these results suggest a novel crosstalk mechanism by which BR signaling coordinates the SA responses mediated by redox-sensitive clade I TGAs.

关键词： brassinosteroid salicylic acid immune responses BIN2 clade I TGA

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Ligand-free monophasic CuPd alloys endow boosted reaction kinetics toward energy-efficient hydrogen fuel production paired with hydrazine oxidation

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Journal of Materials Science & Technology 2023年第12期143卷 20-29页

作者： Yujeong jeong Shreyanka Shankar Naik Yiseul Yu Jayaraman Theerthagiri Seung Jun Lee Pau Loke Show hyun Chul Choi Myong Yong Choi Department of Chemistry(BK21 FOUR) Research Institute of Natural SciencesGyeongsang National UniversityJinju 52828Republic of Korea Core-Facility Center for Photochemistry&Nanomaterials Gyeongsang National UniversityJinju 52828Republic of Korea Zhejiang Provincial Key Laboratory for Subtropical Water Environment and Marine Biological Resources Protection Wenzhou UniversityWenzhou 325035China Department of Chemical and Environmental Engineering Faculty of Science and EngineeringUniversity of Nottingham MalaysiaJalan Broga43500 SemenyihSelangor Darul EhsanMalaysia Department of Chemistry Chonnam National UniversityGwangju 61186Republic of Korea

Optimizing the structure and components is a prevalent strategy for increasing electrocatalytic energy-saving H 2 fuel *** of the sustainable and efficient techniques is electrocatalytic water split-ting for H 2 generation,but it is still restricted by the kinetically sluggish *** to the lower standard oxidation potential of−0.33 V,replacing the OER with anodic hydrazine oxidation reaction(HzOR)is an effective way to extensively reduce the use of electricity in water *** alloying,the semiconductor and adsorption characteristics of Cu,interlaced by Pd 2+solution on the Pd surface by pulsed laser ablation(PLA)in methanol,are selectively altered to maximize cathodic HER and anodic HzOR *** optimal Cu1Pd3/C ratio demonstrates outstanding HER performance with a low overpotential of 0.315 V at 10 mA cm^(−2),as well as an ultralow overpotential of 0.560 V for HzOR in 0.5 M N_(2) H_(4)/1.0 M ***,the constructed HzOR-assisted electrolyzer cell with Cu1Pd3/C||Cu1Pd3/C as anode and cathode exhibits a cell voltage of 0.505 V at 10 mA cm^(−2) with exceptional en-durance over 5 *** current study advances competent CuPd alloys as multifunctional electrocatalysts for H 2 fuel production using a HzOR-assisted energy-efficient electrolyzer.

关键词： PLA CuPd alloy Sonochemical process HzOR Hydrazine evolution reaction Hydrazine splitting Water splitting

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Engineering electrode interfaces for telecom-band photodetection in MoS_(2)/Au heterostructures via sub-band light absorption

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Light(Science & Applications) 2023年第12期12卷 2677-2687页

作者： Chengyun Hong Saejin Oh Vu Khac Dat Sangyeon Pak SeungNam Cha Kyung-hun Ko Gyung-Min Choi Tony Low Sang-hyun Oh Ji-Hee Kim Department of Energy Science Sungkyunkwan UniversitySuwon 16419Republic of Korea Center for Integrated Nanostructure Physics(CINAP) Institute for Basic Science(IBS)Sungkyunkwan UniversitySuwon 16419Republic of Korea School of Electronic and Electrical Engineering Hongik UniversitySeoul 04066Republic of Korea Department of Physics Sungkyunkwan UniversitySuwon 16419Republic of Korea Department of Electrical and Computer Engineering University of MinnesotaMinneapolisMN 55455USA Department of Physics Pusan National UniversityBusan 46241Republic of Korea

Transition metal dichalcogenide(TMD)layered semiconductors possess immense potential in the design of photonic,electronic,optoelectronic,and sensor ***,the sub-bandgap light absorption of TMD in the range from near-infrared(NIR)to short-wavelength infrared(SWIR)is insufficient for applications beyond the bandgap ***,we report that the sub-bandgap photoresponse of MoS_(2)/Au heterostructures can be robustly modulated by the electrode fabrication method *** observed up to 60%sub-bandgap absorption in the MoS_(2)/Au heterostructure,which includes the hybridized interface,where the Au layer was applied via sputter *** greatly enhanced absorption of sub-bandgap light is due to the planar cavity formed by MoS_(2) and Au;as such,the absorption spectrum can be tuned by altering the thickness of the MoS_(2) *** in the SWIR wavelength range increases due to increased absorption,which means that broad wavelength detection from visible toward SWIR is *** also achieved rapid photoresponse(~150μs)and high responsivity(17 mA W^(-1))at an excitation wavelength of *** findings demonstrate a facile method for optical property modulation using metal electrode engineering and for realizing SWIR photodetection in wide-bandgap 2D materials.

关键词： MoS_(2) absorption electrode

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