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Neurological consequences of human calmodulin mutations

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Neural Regeneration Research 2024年第5期19卷 943-944页

作者： helene h.jensen Anders Olsen Medical Biotechnology Department of Chemistry and BiosciencesAalborg UniversityAalborgDenmark

When calcium ions enter the cytosol,it is a stimulatory signal for cellular *** calcium sensor calmodulin picks up the change in calcium concentration and relays this information to its more than 300 downstream interaction *** this way,calmodulin affects cellular processes such as fertilization,muscle contraction,neuronal firing,and *** is,calmodulin is involved in(nearly)everything!The significance of calmodulin is emphasized by the fact that we all carry three different genes(CALM1,2,3)on different chromosomes that encode the exact same calmodulin protein,and these are all expressed in all cell ***,throughout vertebrate evolution,the protein sequence has remained completely unchanged.

关键词： consequences unchanged calmodulin

Applying Synchronous Condenser for Damping Provision in Converter-dominated Power System

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Journal of Modern Power Systems and Clean Energy 2021年第3期9卷 639-647页

作者： ha Thi Nguyen Guangya Yang Arne hejde Nielsen Peter hΦjgaard jensen Bikash Pal the Department of Electrical Engineering Danmarks Tekniske UniversitetRoskildeDenmark the Electrical Engineering Technical University of DenmarkLyngbyDenmark Siemens AG Sektor Energie BallerupDenmark the Department of Electrical and Electronic Engineering Imperial College LondonLondonUK

The dynamic characteristics of converter-dominated systems are governed by controlling power converters and the interactions between converter systems and conventional *** oscillations can appear under dynamic operation conditions caused by the phase-locked loop dynamics and interactions among the converter control *** oscillations may be poorly damped,which can result in reduced power generation,longer settling time,or disconnections of sensitive *** is foreseeable that damping services will be critical for power grid stabilization in the future with high penetration of renewable *** this work,synchronous condensers(SCs)are evaluated and applied to provide damping services to the power grid under post-event *** innovative supplementary controller for the automatic voltage regulator of SCs is proposed to improve the frequency stabilization in a converter-dominated system after *** local and remote measurements,SCs are able to modulate the reactive power output and hence,the terminal bus voltage,which further impacts the power flow in the system;therefore,damping can be provided to the frequency *** control is implemented on an industrial-level hardware platform,and the performance is verified by the hardware-in-the-loop simulation.

关键词： Power oscillation Prony analysis low-inertia system supplementary controller synchronous condenser(SC)

Power hardware in the loop validation of fault ride through of VSC hVDC connected offshore wind power plants

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Journal of Modern Power Systems and Clean Energy 2014年第1期2卷 23-29页

作者： Ranjan ShARMA Qiuwei WU Seung Tae ChA Kim h.jensen Tonny W.RASMUSSEN JacobØSTEGAARD Siemens Wind Power A/S Borupvej 167330 BranderDenmark Centre for Electric Power and Energy Department of Electrical EngineeringTechnical University of DenmarkElektrovej 3252800 Kongens LyngbyDenmark

This paper presents the power hardware in the loop(PhIL)validation of a feed forward DC voltage control scheme for the fault ride through(FRT)of voltage source converter(VSC)high voltage DC(hVDC)connected offshore wind power plants(WPPs).In the proposed FRT scheme,the WPP collector network AC voltage is actively controlled by considering both the DC voltage error and the AC current from the WPP AC collector system which ensures fast and robust FRT of the VSC hVDC connected offshore *** PhIL tests were carried out in order to verify the efficacy of the proposed feed forward DC voltage control scheme for enhancing the FRT capability of the VSC hVDC connected *** PhIL test results have demonstrated the proper control coordination between the offshore WPP and the WPP side VSC and the efficient FRT of the VSC hVDC connected WPPs.

关键词： Fault ride through high voltage DC(hVDC) Offshore wind power plant Power hardware in the loop(PhIL) Voltage source converter(VSC)

Rewiring host–microbe interactions and barrier function during gastrointestinal inflammation

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Gastroenterology Report 2022年第1期10卷 3-17页

作者： Sune K.jensen Simone I.Pærregaar Emma P.Brandum Astrid S.Jørgensen Gertrud M.hjortø Benjamin A.h.jensen Department of Biomedical Sciences Faculty of Health and Medical SciencesUniversity of CopenhagenCopenhagenDenmark

Organismal survival depends on a well-balanced immune system and maintenance of host–microbe *** finetuned relationship between the gut microbiota and host immunity is constantly challenged by opportunistic bacteria testing the integrity of gastrointestinal(GI)barrier *** dysfunction reduces immunological tolerance towards otherwise innocuous microbes;it is a process that may instigate chronic ***,sustained inflammation further diminishes barrier function,enabling bacterial translocation to extra-intestinal *** translocated,these bacteria stimulate systemic inflammation,thereby compromising organ *** genetic risk alleles associate with barrier dysfunction,environmental stressors are key triggers of GI inflammation and associated breakdown in immune tolerance towards resident gut *** dietary components dictate substrate availability,they also orchestrate microbiota composition and function,including migratory and pro-inflammatory potential,thus holding the capacity to fuel both GI and extra-intestinal ***,Western diet consumption may weaken barrier defenses via curbed Paneth cell function and diminished host-defense peptide *** review focuses on intervenable niches of host–microbe interactions and mucosal immunity with the ambition to provide a framework of plausible strategies to improve barrier function and regain tolerance in the inflamed mucosa via nutritional intervention.

关键词： host-defense peptides mucosal barrier defects IBD nutritional immunology bacterial translocation

Lesson Learnt from the 2004 Tsunami:The Effect of Well Cleaning on Groundwater Quality in Coastal Aquifers in Sri Lanka

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地学前缘 2009年第S1期16卷 18-19页

作者： Meththika Vithanage K.G.Villholth K.Mahatantila P.Engesgaard K.h.jensen Department of Geography and Geology University of Copenhagen Geological Survey of Denmark and Greenland Department of Material Science Interdisciplinary Faculty of Science and EngineeringShimane University

On December 26,2004,the Indian Ocean tsunami waves hit Sri Lanka resulting in the devastation of the coastal aquifers from saltwater *** an attempt to speed up the cleaning process of the contaminated water in wells,large-scale and intensive campaigns went into cleaning and rehabilitating wells through pumping out saline water(physical cleansing). however,it was unclear whether these attempts improved the well-water quality,especially in terms of salinity due to density driven flow and solute transport *** in water quality of a sand aquifer on the east coast of Sri Lanka owing to the December 26,2004 tsunami and

关键词： groundwater quality coastal aquifers Sri Lanka Tsunami

Multifunction Zno/carbon hybrid nanofiber mats for organic dyes treatment via photocatalysis with enhanced solar-driven evaporation

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Frontiers of Materials Science 2022年第4期16卷 93-104页

作者： Wenxin WANG Yang ChEN Ning WANG Zhiqiang DU Martin jensen Zihan AN Xianfeng LI State Key Laboratory of Separation Membranes and Membrane Processes Tianjin Municipal Key Lab of Advanced Energy Storage Material and DevicesSchool of Material Science and EngineeringTiangong UniversityTianjin 300387China Department of Chemistry and Bioscience Aalborg UniversityDK-9220 AalborgDenmark The Institute of Seawater Desalination and Multipurpose Utilization(MNR) Tianjin 300192China

ZnO-based photocatalytic materials have received widespread attention due to their usefulness than other photocatalytic materials in organic dye wastewater ***,its photocatalytic efficiency and surface stability limit further *** paper uses a one-step carbonization method to prepare multifunctional ZnO/carbon hybrid nanofiber *** carbonization creates aπ-conjugated carbonaceous structure of the mats,which prolongs the electron recovery time of ZnO nanoparticles to yield improved photocatalytic ***,the carbonization reduces the fiber diameter of the carbon hybrid nanofiber mats,which quadruples the specific surface area to yield enhanced adsorption and photocatalytic *** the same time,the prepared nanofiber mats can increase the evaporation rate of water under solar irradiation to a level of 1.46 kg·m^(-2)·h^(-1)with an efficiency of 91.9%.Thus,the nanofiber mats allow the facile incorporation of photocatalysts to clean contaminated water through adsorption,photodegradation,and interfacial heat-assisted distillation mechanisms.

关键词： hybrid nanofiber mats zinc oxide photocatalysis solar-driven evaporation

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采用波纹管测试水泥基材料早期自收缩方法

硅酸盐学报 2009年第1期37卷 39-45页

作者：田倩 jensen Ole Mejlhede 丹麦科技大学江苏省建筑科学研究院有限公司南京210008

用特制的波纹管模具,可以在塑性阶段以水平方向测长度的方式将体积应变转换为长度应变来测量,不仅能实现自浇注成型开始对水泥基材料自收缩的连续监测,而且可以有效避免重力、温度变化以及模具约束对于测试结果的影响。介绍了波纹管测... 详细信息

用特制的波纹管模具,可以在塑性阶段以水平方向测长度的方式将体积应变转换为长度应变来测量,不仅能实现自浇注成型开始对水泥基材料自收缩的连续监测,而且可以有效避免重力、温度变化以及模具约束对于测试结果的影响。介绍了波纹管测长度的原理,研究了波纹管的材质、尺寸和内部空气对于测试结果的影响。结果表明:测试结果受到波纹管材质、尺寸和成型引入空气的影响;随着波纹管内试件的刚度不断增加,其影响程度也随之减小,到终凝10 h后这种影响可以忽略不计。

关键词：混凝土自收缩波纹管测试方法

A Perturbation of jensen *-Derivations from K(h)into K(h)

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Analysis in Theory and Applications 2016年第4期32卷 333-338页

作者： h.Reisi Department of Mathematics Semnan University

Let＇s take h as an infinite-dimensional hilbert space and K（h） be the set of all compact operators on h. Using Spectral theorem for compact self-adjoint operators, we prove the hyers-Ulam stability of jensen z-deri... 详细信息

关键词： jensen *-derivation C^*-algebra hyers-Ulam stability.

Clinical outcome after surgery on schwannomas in the extremities

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World Journal of Orthopedics 2021年第10期12卷 760-767页

作者： Andreas Saine Granlund Michala Skovlund Sørensen Claus Lindkær jensen Birthe højlund Bech Michael Mørk Petersen Musculoskeletal Tumor Section Department of Orthopedic SurgeryCopenhagen University HospitalRigshospitaletCopenhagen 2100Denmark Department of Orthopedic Surgery Copenhagen University HospitalCopenhagen 2200Denmark Musculoskeletal Tumor Section Department of Orthopedic SurgeryUniversity of CopenhagenCopenhagen 2100Denmark Department of Radiology RigshospitaletUniversity of CopenhagenCopenhagen 2100Denmark

BACKGROUND Schwannoma is a benign,encapsulated and slowly growing tumor originating from Schwann cells and is rarely seen in the peripheral nerve *** symptoms are soreness,radiating pain and sensory loss combined with a soft tissue *** To evaluate pre-and postoperative symptoms in patients operated for schwannomas in the extremities and investigate the rate of malignant *** In this single center retrospective study design,all patients who had surgery for a benign schwannoma in the extremities from May 1997 to January 2018 were *** location of the tumor in the extremities was divided into five groups;forearm,arm,shoulder,thigh and leg including *** locations of the tumor in the nerves were also categorized as either;proximal,distal,minor or major *** the pre-and postoperative clinical evaluation,symptoms were classified as paresthesia,local pain,radiating pain,swelling,impairment of mobility/strength and asymptomatic tumors that were found incidentally(with magnetic resonance imaging).The patients were evaluated after surgery using the following categories:Asymptomatic or symptomatic patients(radiating and/or local pain)and those with *** follow up period was from the time of surgery until last examination of the particular *** logistic regression analysis was performed to identify independent prognostic factors for postoperative significant symptoms at *** We identified 858 cases from the institutional pathology *** excluded cases with duplicate diagnoses(n=407),pathology not including schwannomas(n=157),lesions involving the torso,spine and neck(n=150)leaving 144 patients for further *** this group 99 patients underwent surgery and there were five complications recorded:2 infections(treated with antibiotics)and 3 nerve palsies(2 involving the radial nerve and one involving the median nerve)that recovered *** the end of follow-up,1.4

关键词： Schwannoma Extremities Surgery Removal Symptoms Outcome