检索结果-南通市图书馆

Wear dependent virtual flow rate sensor for progressing cavity pumps with deformable stator

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Petroleum Science 2024年第2期21卷 1346-1353页

作者： jens Müller Sebastian Leonow Johannes Schulz christian Hansen Martin Monnigmann Ruhr-Universitat Bochum Universit atsstraûe 150Bochum44801Germany SEEPEX GmbH Scharnh olzstraûe 344Bottrop46240Germany

This contribution presents a novel wear dependent virtual flow rate sensor for single stage single lobe progressing cavity pumps. We study the wear-induced material loss of the pump components and the impact of this material loss on the volumetric efficiency. The results are combined with an established backflow model to implement a backflow calculation procedure that is adaptive to wear. We use a laboratory test setup with a highly abrasive fluid and operate a pump from new to worn condition to validate our approach. The obtained measurement data show that the presented virtual sensor is capable of calculating the flow rate of a pump being subject to wear during its regular operation.

关键词： Backflow Progressing cavity pump Virtual sensor Wear

Advanced brain organoids for neuroinflammation disease modeling

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第1期19卷 154-155页

作者： Sonia Sabate-Soler Henry Kurniawan jens christian Schwamborn Luxembourg Centre for Systems Biomedicine University of LuxembourgEsch-sur-AlzetteLuxembourg

Brain organoids mimic closely the embryonic human brain:Over the last decade,the development of human organoid systems has evolved *** tissues have been modeled with organoids,such as the gut,lung,liver,kidney retina and *** systems have a high cellular heterogeneity,with many cell types integrated into the same ***'cellular populations interact between and amongst each other in a cellular and molecular level,which represents an advantage with respects to monolayer 2D cell culture systems.

关键词： inflammation lung kidney

Small mammal community composition impacts bank vole (Clethrionomys glareolus) population dynamics and associated seroprevalence of Puumala orthohantavirus

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integrative Zoology 2024年第1期19卷 52-65页

作者： Felicitas Maria BUJNOCH Daniela REIL Stephan DREWES Ulrike MROSENFELD Rainer G.ULRICH jens JACOB christian IMHOLT Julius Kühn-Institute Federal Research Centre for Cultivated PlantsInstitute for Epidemiology and Pathogen DiagnosticsRodent ResearchMünsterGermany University of Münster Institute for Evolution and BiodiversityMünsterGermany Friedrich-Loeffler-Institut Federal Research Institute for Animal HealthInstitute of Novel and Emerging Infectious DiseasesGreifswald-Insel RiemsGermany

Rodents are important reservoirs for zoonotic pathogens that cause diseases in *** is hypoth-esized to be closely related to pathogen prevalence through multiple direct and indirect *** example,the presence of non-host species can reduce contact rates of the main reservoir host and thus reduce the risk of transmission(“dilution effect”).In addition,an overlap in ecological niches between two species could lead to increased interspecific competition,potentially limiting host densities and reducing density-dependent pathogen transmission *** this study,we investigated the relative impact of population-level regulation of direct and indirect drivers of the prevalence of Puumala orthohantavirus(PUUV)in bank voles(Clethrionomys glareolus)during years with high *** compiled data on small mammal community composition from four regions in Germany between 2010 and *** equation modeling revealed a strong seasonality in PUUV control mechanisms in bank *** abundance of shrews tended to have a negative relationship with host abundance,and host abundance positively influenced PUUV seroprevalence,while at the same time increasing the abundance of competing non-hosts like the wood mouse(Apodemus sylvaticus)and the yellow-neckedfield mouse(Apodemusflavicollis)were associated with reduced PUUV seroprevalence in the *** results indicate that for PUUV in bank voles,dilution is associated with increased interspecific *** pressures leading to the decline of Apodemus *** a specific habitat could lead to the amplification of mechanisms promoting PUUV transmission within the host populations.

关键词： bank vole biodiversity Puumala orthohantavirus small mammals

Wind farms increase land surface temperature and reduce vegetation productivity in the Inner Mongolia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geography and Sustainability 2024年第3期5卷 319-328页

作者： Luyao Liu Pengtao Liu Jiawei Yu Gang Feng Qing Zhang jens-christian Svenning Ministry of Education Key Laboratory of Ecology and Resource Use of the Mongolian Plateau School of Ecology and EnvironmentInner Mongolia UniversityHohhot 010021China Key Laboratory of Forest Ecology and Management Institute of Applied EcologyChinese Academy of SciencesShenyang 110016China College of Resources and Environment University of Chinese Academy of SciencesBeijing 100049China Inner Mongolia Autonomous Region Ecological and Agricultural Meteorological Centre Hohhot 010051China e Collaborative Innovation Center for Grassland Ecological Security(Jointly Supported by the Ministry of Education of China and Inner Mongolia Autonomous Region) Hohhot 010021China Center for Ecological Dynamics in a Novel Biosphere(ECONOVO) Department of BiologyAarhus UniversityNy Munkegade 114Aarhus C DK-8000Denmark Center for Biodiversity Dynamics in a Changing World(BIOCHANGE) Department of BiologyAarhus UniversityNy Munkegade 114Aarhus C DK-8000Denmark

Wind power has been developing rapidly as a key measure to mitigate human-driven global *** under-standing of the development and impacts of wind farms on local climate and vegetation is of great importance for their rational use but is still *** this study,we combined remote sensing and on-site investigations to identify wind farm locations in Inner Mongolia and performed landscape pattern analyses using *** explored the impacts of wind farms on land surface temperature(LST)and vegetation net primary productivity(NPP)between 1990 and 2020 by contrasting these metrics in wind farms with those in non-wind farm *** results showed that the area of wind farms increased rapidly from 1.2 km2 in 1990 to 10,755 km2 in ***,wind farms are mainly clustered in three aggregation areas in the ***,wind farms increased nighttime LST,with a mean value of 0.23℃,but had minor impacts on the daytime ***,wind farms caused a decline in NPP,especially over forest areas,with an average reduction of 12.37 GC/m^(2).Given the impact of wind farms on LST and NPP,we suggest that the development of wind farms should fully consider their direct and potential *** study provides scientific guidance on the spatial pattern of future wind farms.

关键词： Wind farm Landscape pattern LST NPP Inner Mongolia

Development of fungal cell factories for the production of secondary metabolites:Linking genomics and metabolism

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Synthetic and Systems Biotechnology 2017年第1期2卷 5-12页

作者： jens christian Nielsen jens Nielsen Chalmers University of Technology Kemivagen 10Sweden

The genomic era has revolutionized research on secondary metabolites and bioinformatics methods have in recent years revived the antibiotic discovery process after decades with only few new active molecules being *** computational tools are driven by genomics and metabolomics analysis,and enables rapid identification of novel secondary *** translate this increased discovery rate into industrial exploitation,it is necessary to integrate secondary metabolite pathways in the metabolic engineering *** this review,we will describe the novel advances in discovery of secondary metabolites produced by filamentous fungi,highlight the utilization of genome-scale metabolic models(GEMs)in the design of fungal cell factories for the production of secondary metabolites and review strategies for optimizing secondary metabolite production through the construction of high yielding platform cell factories.

关键词： Secondary metabolism Fungi Biosynthetic gene clusters Genome mining Metabolic modeling Cell factories

Bistability theorem in a cancer model

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Biomathematics 2018年第1期11卷 61-98页

作者： jens christian Larsen Vanlcse Alle 50 2. mr. tv2720 VanlCse Copenhagen Denmark

In this paper, I continue the study of the mathematical models presented in [J. C. Larsen, Models of cancer growth, J. Appl. Math. Comput. 53（1-2）（2015） 613-645] and [J. C. Larsen, The bistability theorem in a model of metastatic cancer, to appear in Appl. Math.]. I shall prove the bistability theorem for the ODE model from [Larsen, 2015]. It is a mass action kinetic system in the variables C cancer, GF growth factor and GI growth inhibitor. This theorem says that for some values of the parameters, there exist two positive singular points c＊＋ = （C＊＋, GF＊., GI＊＋）, c＊2- = （C＊-, GF＊, GI＊-） of the vector field. Here C＊- 〈 C＊＋ and e. is stable and c＊＋ is unstable, see Sec. 2. There is also a discrete model in [Larsen, 2015], it is a linear map （T） on three-dimensional Euclidean vector space with variables （C, GF, GI）, where these variables have the same meaning as in the ODE model above. In [Larsen, 2015], I showed that one can sometimes find attine vector fields on three-dimensional Euclidean vector space whose time one map is T. I shall also show this in the present paper in a more general setting than in [Larsen, 2015]. This enables me to find an expression for the rate of change of cancer growth on the coordinate hyperplane C = 0 in Euclidean vector space. I also present an ODE model of cancer metastasis with variables C, CM, CF,GI, where C is primary cancer and CM is metastatic cancer and GF, GI are growth factors and growth inhibitors, respectively.

关键词： Immunology cancer chemotherapy immune therapy discrete dynamicalsystem Gompertz function.

Is serine racemase(SRR) a second hit target for LRRK2-G2019S induced Parkinson's disease?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2021年第3期16卷 498-499页

作者： Sarah Louise Nickels jens christian Schwamborn Luxembourg Centre for Systems Biomedicine(LCSB) University of LuxembourgBelvauxLuxembourg Riken Institute for Medical Sciences(IMS) KanagawaJapan

To date,at least 7 million people are suffering from Parkinson's disease(PD)worldwide,which is the second most prevalent,age-associated,and progressive neurodegenerative disorder(Tysnes and Storstein,2017).Given the accelerated global pace of aging,it becomes of fundamental importance that we start understanding the origins of neurodegeneration in order to develop effective disease modifying *** PD patients suffer from a combination of motor and nonmotor disabilities.

关键词： second patients suffering

A concurrent optimization approach for energy efficient multiple axis positioning tasks

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Control and Decision 2016年第4期3卷 223-247页

作者： christian Hansen jens Kotlarski Tobias Ortmaier Institute of Mechatronic Systems Leibniz Universitat HannoverHanoverGermany

Automated production systems typically comprise numerous electrical servo drives,many of which conduct positioning motions,*** handling or manipulation *** power electronics of modern multi-axis systems often comprise coupled DC-links,enabling for internal exchange of recuperative brake ***,the motion sequences of manipulators are often commanded at maximum dynamics for minimum time motion,neglecting possible optimization potential,*** idle time,leading to inefficient energy management.A robust trajectory optimization approach based on the particle swarm algorithm and well-established path planning methods is presented for the adaption of multi-axis positioning tasks with only two parameters per axis and positioning motion during system *** results prove that,depending on the positioning task and chosen optimization constraints,energy demands are distinctly *** approach is applicable to diverse multi-axis configurations and enables for considerable energy savings without additional hardware invest.

关键词： Multiple axis systems electrical servo drive energy efficient control trajectory optimization positioning tasks

Ethyl-iophenoxic acid as a quantitative bait marker for small mammals

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Integrative Zoology 2022年第6期17卷 981-990页

作者： Kyra JACOBLINNERT christian IMHOLT Detlef SCHENKE jens JACOB Julius Kühn Institute(JKI) Federal Research Centre for Cultivated PlantsInstitute for Plant Protection in Horticulture and ForestsVertebrate ResearchMünsterGermany Department of Behavioral Biology University of OsnabrückOsnabrückGermany Julius Kühn Institute(JKI) Federal Research Centre for Cultivated PlantsInstitute for Ecological ChemistryPlant Analysis and Stored Product ProtectionBerlinGermany

Bait markers are indispensable for ecological research but in small mammals,most markers are invasive,expensive and do not enable quantitative analyses of ***-iophenoxic acid(Et-IPA)is a non-toxic,quantitative bait marker,which has been used for studying bait uptake in several carnivores and *** developed a bait with Et-IPA,assessed its palatability to common voles(Microtus arvalis),and determined the dose-residue-relation for this important agricultural pest rodent ***-IPA concentrations of 40 to 1280μg Et-IPA per g bait were applied to wheat using sunﬂower oil or polyethylene glycol 300 as potential *** a laboratory study,common voles were offered the bait and blood samples were collected 1,7,and 14 days after *** samples were analyzed with LC-ESI-MS/MS for blood residues of ***ﬂower-oil was the most suitable bait ***-IPA seemed to be palatable to common voles at all test ***-dependent residues could be detected in blood samples in a dose-dependent manner and up to 14 days after uptake enabling generation of a calibration curve of the dose-residue ***-IPA was present in common vole blood for at least 14 days,but there was dissipation by 33–37%depending on ***-IPA meets many criteria for an“ideal”quantitative bait marker for use in futureﬁeld studies on common voles and possibly other small mammal species.

关键词： baiting biomarker Microtus arvalis quantitative bait marker small mammals