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Analysis of identification methods of key nodes in transportation network

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chinese Physics B 2022年第6期31卷 782-789页

作者： Qiang lai Hong-Hao Zhang School of Electrical and Automation Engineering East China Jiaotong UniversityNanchang 330013China

The identification of key nodes plays an important role in improving the robustness of the transportation *** different types of transportation networks,the effect of the same identification method may be *** is of practical significance to study the key nodes identification methods corresponding to various types of transportation *** on the knowledge of complex networks,the metro networks and the bus networks are selected as the objects,and the key nodes are identified by the node degree identification method,the neighbor node degree identification method,the weighted k-shell degree neighborhood identification method(KSD),the degree k-shell identification method(DKS),and the degree k-shell neighborhood identification method(DKSN).Take the network efficiency and the largest connected subgraph as the effective *** results show that the KSD identification method that comprehensively considers the elements has the best recognition effect and has certain practical significance.

关键词： transportation network key node identification KSD identification method network efficiency

MicroRNA expression profiles and functions in the brain

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Neural Regeneration Research 2008年第12期3卷 1380-1385页

作者： Yanting Qi Yu Zhao Zhuyin chen Xiaona chen Marie c. Lin Xiangfu Kong Lihui lai Institute of Molecular and chemical Biology East China Normal University Shanghai 200062 China Stanley Ho centre for Emerging Infectious Diseases Faculty of Medicine The Chinese University of Hong Kong Hong Kong SpecialAdministrative Region China Department of chemistry Open Laboratory of Chemical Biology University of Hong Kong Hong Kong Special Administrative Region China

MicroRNAs are abundant in the brains of vertebrates and some show a brain-specific or brain-enriched expression pattern. Because microRNAs regulate the expression of hundreds of target genes, it is not surprising that they have profoundly important functions in brain development and pathological processes. For example, miR-124 plays an important role in inducing and maintaining neuronal identity through targeting at least two anti-neural factors. MicroRNAs have also been implicated in brain disorders, including brain tumors and neurodegenerative diseases. This review aims to present an overview of the expression profiles and functions of microRNAs in the developing brains of vertebrates.

关键词： neurogenesis neural cell specification synaptic plasticity posttranscriptional regulator epigenetic control

STAG-cNS： An Order-Aware conserved Noncoding Sequences Discovery Tool for Arbitrary Numbers of Species

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Molecular Plant 2017年第7期10卷 990-999页

作者： Xianjun lai Sairam Behera Zhikai Liang Yanli Lu Jitender S. Deogun James c. Schnable Department of Agronomy and Horticulture Center for Plant Science innovation University of Nebraska-Lincoln Lincoln NE 68588 USA Department of computer Science and Engineering University of Nebraska-Lincoln Lincoln NE 68588 USA Maize Research Institute Sichuan Agricultural University Chengdu 611130 China

One method for identifying noncoding regulatory regions of a genome is to quantify rates of divergence between related species, as functional sequence will generally diverge more slowly. Most approaches to identifying these conserved noncoding sequences （cNSs） based on alignment have had relatively large minimum sequence lengths （≥15 bp） compared with the average length of known transcription factor binding sites. To circumvent this constraint, STAG-cNS that can simultaneously integrate the data from the promoters of conserved orthologous genes in three or more species was developed. Using the data from up to six grass species made it possible to identify conserved sequences as short as 9 bp with false discovery rate ≤0.05. These cNSs exhibit greater overlap with open chromatin regions identified using DNase I hypersensitivity assays, and are enriched in the promoters of genes involved in transcriptional regulation. STAG-cNS was further employed to characterize loss of conserved noncoding sequences associated with retained duplicate genes from the ancient maize polyploidy. Genes with fewer retained cNSs show lower overall expression, although this bias is more apparent in samples of complex organ systems containing many cell types, suggesting that cNS loss may correspond to a reduced number of expression contexts rather than lower expression levels across the entire ancestral expression domain.

关键词： conserved noncoding sequence comparative genomics suffix tree longest path algorithm grain crops

Photocatalytic degradation of Rhodamine B by microwave-assisted hydrothermal synthesized N-doped titanate nanotubes

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Journal of Environmental Sciences 2014年第7期26卷 1505-1512页

作者： caiyun Yan Ku-Fan chen chia-Hsiang lai Shiau-Wu lai Qing chang Yen-Ping Peng School of Environmental and Municipal Engineering Lanzhou Jiaotong University Department of civil Engineering National Chi Nan University Department of Safety Health and Environmental Engineering Central Taiwan University of Science and Technology college of Environment and Energy South China University of Technology

Microwave-induced nitrogen-doped titanate nanotubes（NTNTs） were characterized by transmission electron microscopy（TEM）, X-ray diffraction（XRD）, X-ray photoelectron spectroscopy（XPS）, Fourier transform infrared spectroscopy（FT-IR）, Zeta potential analysis,specific surface area（SBET）, and UV-Visible spectroscopy. TEM results indicate that NTNTs retain a tubular structure with a crystalline multiwall and have a length of several hundred nanometers after nitrogen doping. XRD findings demonstrate that the crystalline structure of NTNTs was dominated by anatase, which is favored for photocatalytic application. The Ti-O-N linkage observed in the XPS N 1s spectrum is mainly responsible for narrowing the band gap and eventually enhancing the visible light photoactivity. FT-IR results demonstrated the existence of H3O＋, which could be excited by photo-generated holes to form hydroxyl radicals and degrade environmental pollutants. After sintering at 350°c, the UV-Vis absorbance edges of NTNTs significantly shift to the visible-light region, which indicates N atom doping into the nanotubes. Photocatalytic degradation of Rhodamine B（RhB） via NTNTs show good efficiency, with pseudo first-order kinetic model rate constants of 3.7 × 10-3, 2.4 × 10-3and 8.0 × 10-4sec-1at pH 3, 7, and 11, respectively.

关键词： Microwave hydrothermal Titanate nanotubes Photocatalytic degradation

First Digit Distributions of Gamma-Ray Bursts

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Research in Astronomy and Astrophysics 2024年第5期24卷 70-75页

作者： Hou-Yu lai Jun-Jie Wei Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China School of Astronomy and Space Sciences University of Science and Technology of ChinaHefei 230026China

The occurrence of the first significant digits from real world sources is usually not equally distributed,but is consistent with a logarithmic distribution instead,known as Benford’s *** this work,we perform a comprehensive investigation on the first digit distributions of the duration,fluence,and energy flux of gamma-ray bursts (GRBs) for the first *** a complete GRB sample detected by the Fermi satellite,we find that the first digits of the duration and fluence adhere to Benford’s ***,the energy flux shows a significant departure from this law,which may be due to the fact that a considerable part of the energy flux measurements is restricted by lack of spectral *** on the conventional duration classification scheme,we also check if the durations and fluences of long and short GRBs (with duration T_(90)>2 s and T_(90)≤2 s,respectively) obey Benford’s *** find that the fluences of both long and short GRBs still agree with the Benford distribution,but their durations do not follow Benford’s *** results hint that the long–short GRB classification scheme does not directly represent the intrinsic physical classification scheme.

关键词： (stars:)gamma-ray burst general-methods statistical-astronomical databases miscellaneous

GENETIc PROGRAMMING TO PREDIcT SKI-JUMP BUcKET SPILLWAY ScOUR

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Journal of Hydrodynamics 2008年第4期20卷 477-484页

作者： AZAMATHULLA H. MD GHANI A. AB ZAKARIA N. A lai S. H cHANG c. K LEOW c. S ABUHASAN Z River Engineering and Urban Drainage Research centre University Sains Malaysia

Researchers in the past had noticed that application of Artificial Neural Networks （ANN） in place of conventional statistics on the basis of data mining techniques predicts more accurate results in hydraulic predictions. Mostly these works pertained to applications of ANN. Recently, another tool of soft computing, namely, Genetic Programming （GP） has caught the attention of researchers in civil engineering computing. This article examines the usefulness of the GP based approach to predict the relative scour depth downstream of a common type of ski-jump bucket spillway. Actual field measurements were used to develop the GP model. The GP based estimations were found to be equally and more accurate than the ANN based ones, especially, when the underlying cause-effect relationship became more uncertain to model.

关键词： Genetic Programming (GP) neural networks spillway scour ski-jump bucket

DISLOcATION DISSOcIATIONS AND FAULTENERGIES IN Ni_3Al ALLOYS DOPED WITH PALLADIUM

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中国有色金属学会会刊:英文版 1999年第S1期9卷 87-94页

作者： J.Sun c.S.Lee J.K.L.lai Open Lab for High Temperature Materials&Tests School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200030China Department of Physics and Materials Science City University of Hong KongHong KongChina

Dislocation structures in polycrystalline Ni 3Al alloy doped with palladium deformed at room temperature have been investigated by transmission electron microscopy. The structure consists mainly of dislocations dissociated into a /2〈011〉 super partials bounding an anti phase boundary (APB). Dislocations dissociated into a /3〈112〉 super Shockley partials bounding a superlattice intrinsic stacking fault (SISF) are also common debris. The majority of the SISFs are truncated loops, i.e. the partials bounding the SISF are of similar Burgers vector. These faulted loops are generated from APB coupled dislocations, according to a mechanism for formation of SISFs proposed by Suzuki et al , and recently modified by chiba et al . The APB energies for {111} and {010} slip planes are measured to be 144±20 mJ/m 2 and 102±11 mJ/m 2 respectively, and the SISF energy has been estimated to be 12 mJ/m 2 in this alloy. It is concluded that the dislocation structure in Ni 74.5 Pd 2Al 23.5 alloy deformed at room temperature is similar to that in binary Ni 3Al, and the difference in fault energies between these two alloys is small. Thus, it seems unlikely that the enhancement of ductility of Ni 74.5 Pd 2Al 23.5 results from only such a small decrease of the ordering energy of the alloy. SISF bounding dislocations also have no apparent influence on the ductilization of Ni 74.5 Pd 2Al 23.5 alloy.

关键词： Ni_(3)Alalloys palladium doption dislocation dissociations fault energies

BcLc staging system and liver transplantation:From a stage to a therapeutic hierarchy

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Hepatobiliary & Pancreatic Diseases International 2021年第1期20卷 4-5页

作者： Quirino lai Alessandro Vitale Hepato-biliary and Organ Transplant Unit Department of SurgerySapienza University of RomeViale del Policlinico 15500161 RomeItaly Department of Surgery Oncology and GastroenterologyUniversity of PaduaPaduaItaly

The Barcelona clinic Liver cancer(BcLc)system was proposed in 1999 with the intent to improve a therapeutic algorithm for the management of patients with hepatocellular carcinoma(Hcc)[1].Both the European and the American Guidelines on the Treatment of Hcc have endorsed the BcLc as the standard staging algorithm with prognostic and therapeutic implications[2,3].The BcLc staging system stratifies Hcc patients into five stages(0,A,B,c and D).According to the algorithm,liver transplantation(LT)is indicated only in patients in the stages BcLc 0 and A,special situations provided.

关键词： therapeutic staging liver

Kinematics and Mechanical Properties Analyses on Vibration converter of Intelligent Damper forDrill Strings

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Advances in Applied Mathematics and Mechanics 2013年第5期5卷 671-687页

作者： Xiaohua Zhu chunlin lai college of Mechatronic Engineering Southwest Petroleum UniversityChengdu 610500SichuanChina

Taking vibration converter of intelligent damper for drill strings as the study object,this paper analyzes the influential factors of motion state of the ball and conducts an explicit dynamics simulation by establishing a mechanics model of vibration *** study basis is Newton’s laws of motion,d’alembert’s principle and hertz contact *** we use world coordinate system,rotating coordinate system and Frenet coordinate system to deduce kinematics equations of vibration *** ultimate result demonstrates that the axial velocity and maximum contact stress change with the increment of ball diameter and helix *** also proves the validity of our derived kinematics and mechanical models and provides a good consultant value for the design and theoretical arithmetic of vibration converter for intelligent damper of drill strings.

关键词： Intelligent damper vibration converter kinematics analysis contact stress