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Geolocator study reveals east African migration route of Central European Common Terns

Avian Research 2020年第1期11卷 34-44页

作者： jelena Kralj Milos Martinovic Luka Jurinovic Peter Szinai Szandra Suto Balint Preiszner Institute of Ornithology Croatian Academy of Sciences and ArtsGunduliceva 2410000 ZagrebCroatia Poultry Centre Croatian Veterinary InstituteHeinzelova 5510000 ZagrebCroatia Balaton-felvideki National Park Directorate Csopak 8229Hungary Department of Limnology University of PannoniaVeszprem 8200Hungary Balaton Limnological Institute MTA Centre for Ecological ResearchTihany 8237Hungary

Background: The majority of European Common Terns(Sterna hirundo) migrate south along the western coast of Europe and Africa, while birds from eastern regions are known to cross the Mediterranean Sea from east to west or migrate along the eastern African coast. The migration route of north European terns wintering along the coast of western Africa was already described using geolocator data, while knowledge about movements of the European inland populations is based only on relatively scarce recoveries of ringed ***: We used light-level geolocators in inland Common Tern colonies in Hungary and Croatia to study their migration route and to identify wintering areas along with stopover sites. Results revealed by geolocators were compared with recoveries of ringed ***: All tracked birds used the east African migration route with autumn stopovers at Lower Nile and in the southern part of the Red Sea, and short spring stopover in Israel. Terns wintered along Kenyan coasts and in the southern Mozambique Channel. Autumn migration lasted four times longer than spring ***: This is the first geolocator study that describes the east African migration route of the Common Tern. Important stopover sites were identified. More studies of inland populations are needed to better elucidate tern winter movements.

关键词： Inland population Light-level geolocators Mozambique Channel Red Sea Sterna hirundo Stopover sites Wintering area

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Impact of Microstructural and Surface Modifications on the Ti-45Nb Alloy’s Response to Bio-Environment

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Acta Metallurgica Sinica(English Letters) 2024年第7期37卷 1215-1230页

作者： Ivana Cvijović-Alagić Slađana Laketić MilošMomčilović Jovan Ciganović jelena Bajat Vesna Kojić Vinča Institute of Nuclear Sciences-National Institute of the Republic of Serbia University of BelgradeMike Petrovića Alasa 12-1411000BelgradeSerbia Faculty of Technology and Metallurgy University of BelgradeKarnegijeva 411000BelgradeSerbia Oncology Institute of Vojvodina Faculty of MedicineUniversity of Novi SadPut Doktora Goldmana 4Sremska Kamenica21204Sremska KamenicaSerbia

The Ti-45Nb (mass%) alloy’s corrosive and biocompatible response in simulated physiological conditions was investigated before and after its additional high-pressure torsion (HPT) and laser irradiation processing. The grain size reduction from 2.76 µm to ~ 200 nm and the appearance of laser-induced morphologically altered and highly oxidized surface led to the significant improvement of alloy corrosion resistance and cell–implant interaction. Moreover, an additional increase of the laser pulse energy from 5 to 15 mJ during the alloy irradiation in the air led to an increase in the surface oxygen content from 13.64 to 23.89% accompanied by an increase of excellent cell viability from 127.18 to 134.42%. As a result of the controlled alloy microstructural and surface modifications, the formation of protective bi-modal mixed Ti- and Nb-oxide external scale was enabled. The presence of this surface oxide scale enhanced the alloy’s resistance to corrosion deterioration and simultaneously boosted cell viability and proliferation.

关键词： Ti-45Nb alloy High-pressure torsion Laser surface scanning Corrosion resistance Biocompatible properties

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Pesticide-induced photoluminescence quenching of ultra-small Eu3+-activated phosphate and vanadate nanoparticles

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Journal of Materials Science & Technology 2020年第3期38卷 197-204页

作者： Jovana Perisa Zeljka Antic Chong-Geng Ma jelena Papan Dragana Jovanovic Miroslav D.Dramicanin Vinca Institute of Nuclear Sciences University of BelgradeP.O.Box 52211001 BelgradeSerbia College of Sciences Chongqing University of Posts and TelecommunicationsChongqing 400065China

The aim of this research was to investigate the luminescent behavior of ultra-small Eu3+-activated phosphate and vanadate nanoparticles in the presence of *** have an average diameter of approximately 2 nm with a narrow size *** monazite crystal structure of phosphate-based particles(space group P121/n1)and single tetragonal zircon-type structure of vanadate-based particles(space group of I41/amd)have been confirmed using X-ray diffraction *** synthesized Eu3+-activated colloidal nanoparticles show sharp emission peaks in the red spectral *** measurements revealed emission quenching upon addition of millimolar concentrations of following pesticides:4-Chloro-2-methyl-phenoxyacetic acid(MCPA),2,4-Dichlorophenoxyacetic acid(2,4-D)and N-(phosphonomethyl)glycine(Glyphosate).In both phosphate and vanadate-based colloidal nanoparticles luminescence quenching is more evident in the presence of 2,4-D pesticide with the lowest limit of detection(0.7μM)obtained for phosphate-based nanoparticles.

关键词： Phosphate/vanadate based colloidal nanoparticles Eu3+ Emission quenching Pesticide

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HCV Extrahepatic Manifestations

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Journal of Clinical and Translational Hepatology 2019年第2期7卷 172-182页

作者： Lucija Kuna jelena Jakab Robert Smolic George Y Wu Martina Smolic Department of Pharmacology and Biochemistry Faculty of Dental Medicine and HealthJ.J.Strossmayer University of OsijekOsijekCroatia Department of Pathophysiology and Physiology with Immunology Faculty of Dental Medicine and HealthJ.J.Strossmayer University of OsijekOsijekCroatia Department of Internal Medicine Faculty of MedicineJ.J.Strossmayer University of OsijekOsijekCroatia Department of Pharmacology Faculty of MedicineJ.J.Strossmayer University of OsijekOsijekCroatia Department of Medicine Division of Gastroenterology-HepatologyUniversity of Connecticut Health CenterFarmingtonCTUSA

Hepatitis C virus(HCV)has been shown to affect many tissues other than ***,of the many extrahepatic manifestations(EMs)that have been associated with HCV,including cryoglobulinemia,lymphoma,insulin resistance,type 2 diabetes and neurological disorders,only a few have been shown to be directly related to HCV infection of extrahepatic ***-triggered immune-mediated mechanisms account for most of the *** is estimated that up to 74%of patients with chronic hepatitis C can develop at least one *** HCV patients with EMs should be considered for antiviral therapy,although not all will resolve with sustained virological response.

关键词： Hepatitis C virus Hepatic stellate cells B cell lymphomas pancreatic B cell TGF-β-dependent signaling pathway Extrahepatic manifestations Direct-acting antivirals

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Low-grade fibromyxoid sarcoma of the liver: A case report

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World Journal of Clinical Cases 2021年第1期9卷 175-182页

作者： Vladimir Dugalic Igor I Ignjatovic jelena Djokic Kovac Nikola Ilic jelena Sopta Slavenko R Ostojic Dragan Vasin Marko D Bogdanovic Igor Dumic Tamara Milovanovic Department of Hepatobiliary&Pancreatic Surgery Clinic for Digestive SurgeryClinical Center of SerbiaBelgrade 11000Serbia Department of Radiology Clinical Center of SerbiaBelgrade 11000Serbia Clinic for Vascular and Endovascular Surgery Clinical Center of SerbiaBelgrade 11000Serbia Institute of Pathology University of BelgradeBelgrade 11000Serbia Mayo Clinic Health System Mayo Clinic College of Medicine and ScienceRochesterNY 10029United States Clinic for Gastroenterology and Hepatology Clinical Center of SerbiaSchool of MedicineUniversity of BelgradeBelgrade 11000Serbia

BACKGROUND Low grade fibromyxoid sarcoma(LGFMS)is a rare and benign mesenchymal tumor with indolent course,most commonly found in young or middle-aged *** majority of the LGFMSs are located in the trunk and deep soft tissue of the lower *** appear as well circumscribed,although not encapsulated,which often leads to incomplete surgical *** their seemingly benign appearance,these tumors have aggressive behavior with high metastatic and recurrence *** histopathologic examination of the specimen and its immunohistochemical analysis are mandatory for a precise *** SUMMARY We report a case of a 38 year-old-man who presented with jaundice and upper abdominal ***-detector computed tomography and magnetic resonance imaging showed a large left liver tumor mass,extending to the hepatoduodenal *** hepatectomy was performed with resection and reconstruction of hepatic artery and preservation of middle hepatic *** examination confirmed the tumor being a low-grade fibromyxoid *** and a half years after surgery,the patient died after being diagnosed with spine *** Due to poor response to all modalities of adjuvant treatment,we consider that the focus of treatment should be on surgery as the only option for curing the disease.

关键词： Fibromyxoid sarcoma Liver Resection Histopathology Case report

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Immune surveillance of cytomegalovirus in tissues

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Cellular & Molecular Immunology 2024年第9期21卷 959-981页

作者： Andrea Mihalić jelenaŽeleznjak Berislav Lisnić Stipan Jonjić Vanda JuranićLisnić Ilija Brizić Center for Proteomics Faculty of MedicineUniversity of RijekaRijekaCroatia Department of Biomedical Sciences Croatian Academy of Sciences and ArtsRijekaCroatia

Cytomegalovirus(CMV),a representative member of the Betaherpesvirinae subfamily of herpesviruses,is common in the human population,but immunocompetent individuals are generally asymptomatic when infected with this ***,in immunocompromised individuals and immunologically immature fetuses and newborns,CMV can cause a wide range of often long-lasting morbidities and even *** is not only widespread throughout the population but it is also widespread in its hosts,infecting and establishing latency in nearly all tissues and ***,understanding the pathogenesis of and immune responses to this virus is a prerequisite for developing effective prevention and treatment *** arms of the immune system are engaged to contain the infection,and general concepts of immune control of CMV are now reasonably well ***,in recent years,tissue-specific immune responses have emerged as an essential factor for resolving CMV *** tissues differ in biology and function,so do immune responses to CMV and pathological processes during *** review discusses state-of-the-art knowledge of the immune response to CMV infection in tissues,with particular emphasis on several well-studied and most commonly affected organs.

关键词： Cytomegalovirus Immune response Pathogenesis Tissue MCMV HCMV

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Modeling of biodiesel production: Performance comparison of Box–Behnken, face central composite and full factorial design

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Chinese Journal of Chemical Engineering 2019年第7期27卷 1690-1698页

作者： Vlada B.Veljkovic Ana V. Velickovic jelena M. Avramovic Olivera S. Stamenkovic University of Nis Faculty of TechnologyBulevar oslobodenja 124Leskovac 16000Serbia Research&Development Center "Alfatec" Bulevar Nikole Tesle 63/5Nis 18000Serbia

The performances of the response surface methodology(RSM)in connection with the Box–Behnken,face central composite or full factorial design(BBD,FCCD or FFD,respectively)were compared for the use in modeling of the NaOH-catalyzed sunflower oil *** influence of temperature,catalyst loading,and ethanol-to-oil molar ratio(EOMR)on fatty acid ethyl esters(FAEE)content was *** three multivariate strategies were efficient in the statistical modeling and optimization of the influential process variables but BBD and FCCD realization involved less number of experiments,generating smaller costs,requiring less work and consuming shorter time than the corresponding *** three designs resulted in the same optimal catalyst loading(1.25%of oil)and EOMR(12:1).The reduced two-factorinteraction(2 FI)models based on the BBD and FCCD defined a range of optimal reaction temperature(25℃–75℃)and 25℃,respectively while the same model based on the 33 FFD appointed 75℃.The predicted FAEE content of about 97%–98.0%was close to the experimentally obtained FAEE content of about 97.0%–97.6%under the optimal reaction ***,the simpler BBD or FCCD might successfully be applied for statistical modeling of biodiesel production processes instead of the more extensive,more laborious and more expensive FFD.

关键词： Biodiesel Box-Behnken design Model reduction Face central composite design Full factorial design Optimization

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Aryl Hydrocarbon Receptor is Involved in the Proinflammatory Cytokine Response to Cadmium

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Biomedical and Environmental Sciences 2021年第3期34卷 192-202页

作者： KULAS jelena TUCOVIC Dina ZELJKOVIC Milica POPOVIC Dusanka POPOV ALEKSANDROV Aleksandra KATARANOVSKI Milena MIRKOV Ivana Immunotoxicology Group Department of EcologyInstitute for Biological Research‘Sinisa Stankovic'-National Institute of Republic of SerbiaUniversity of Belgrade142 Bulevar despota StefanaBelgrade 11000Serbia

Objective To investigate involvement of the aryl hydrocarbon receptor(Ah R)in the immunomodulatory effects of cadmium(Cd).Methods The effect of Cd on Ah R activation(CYP1 A1 and CYP1 B1 m RNA expression)was examined in lung leukocytes of Cd-exposed rats(5 and 50 mg/L,30 d orally)and by in vitro leukocyte *** involvement of Ah R signaling in the effects of Cd on the interleukin(IL)-1β,IL-6,and tumor necrosis factor(TNF)lung leukocyte response was investigated in vitro using the receptor antagonist *** Cd increased CYP1 B1(in vivo and in vitro)and CYP1 A1(in vitro)m RNA,indicating Ah R involvement in the action of *** response to Cd,lung leukocytes increased IL-6 and decreased TNF at the gene expression and protein levels,but decreased IL-1βproduction due to reduced *** Ah R antagonist CH-223191 abrogated the observed effects of Cd on the cytokine *** absence of Ah R reactivity and cytokine response to Cd of leukocytes from the lungs of a rat strain that is less sensitive to Cd toxicity coincided with a high Ah R repressor m RNA *** Ah R signaling is involved in the lung leukocyte proinflammatory cytokine response to *** relevance of the Ah R to the cytokine response to Cd provides new insight into the mechanisms of Cd immunotoxicity.

关键词： Cadmium Lung leukocytes Aryl hydrocarbon receptor Cytokine(IL-6,TNF,IL-1β)response

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Panhypopituitarism caused by a suprasellar germinoma: A case report

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World Journal of Clinical Cases 2024年第10期12卷 1844-1850页

作者： jelena Roganovic Lea Saric Silvije Segulja Ana Dordevic Mia Radosevic Department of Pediatrics Clinical Hospital Centre RijekaRijeka 51000Croatia Faculty of Medicine University of RijekaRijeka 51000Croatia Faculty of Health Sciences University of RijekaRijeka 51000Croatia Department of Business Development Jadran Galenski LaboratorijRijeka 51000Croatia

BACKGROUND Suprasellar germinomas are rare intracranial tumors frequently associated with permanent endocrine *** present the clinical picture,treatment,and complications of suprasellar germinoma at pediatric age which,besides being lifethreatening,has lifelong endocrinological *** SUMMARY A 12-year-old female patient was presented having had intensive headaches for three weeks and visual disturbances for six *** ophthalmological examination revealed bilateral papilledema and a marked loss of *** brain magnetic resonance imaging(MRI)showed a suprasellar tumor,involving the infundibulum and the optic chiasm,extending to the third *** tests confirmed decreased levels of thyroxine,cortisol,gonadotropins,and insulin-like growth factor *** tumor reduction was performed,and immunohistopathology established the diagnosis of suprasellar *** of the spine and cerebrospinal fluid cytology confirmed the localized *** chemotherapy and radiotherapy were performed according to the SIOP CNS GCT II protocol.A post-treatment MRI showed no residual tumor,but pituitary function had not *** and a half years after the end of the treatment,the patient is in a complete remission,requiring hormonal replacement therapy,continuous education,and psychological *** This complex case highlights the importance of timely diagnosis,a multidisciplinary approach,and close follow-up in children with suprasellar germinomas.

关键词： Germinoma Germ cell tumor Suprasellar tumor Hypopituitarism Management Pediatrics Case report

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Co-expression of the proteinase inhibitors oryzacystatin I and oryzacystatin II in transgenic potato alters Colorado potato beetle larval development

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Insect Science 2017年第5期24卷 768-780页

作者： Aleksandar Cingel jelena Savic Jelica Lazarevic Tatjana Cosic Martin Raspor Ann Smigocki Slavica Ninkovic Institute for Biological Research 'Sinisa Stankovic' University of Belgrade Bulevar despota Stefana 142 Belgrade Serbia USDA-ARS Molecular Plant Pathology Laboratory 10300 Baltimore Avenue Beltsville Maryland USA

Colorado potato beetle （CPB; Leptinotarsa decemlineata Say, Coleoptera： Chrysomelidae） has shown a remarkable adaptability to a variety of control measures. Although oryzacystatin I and II （OCI and OCII） have potential in controlling pests that use cysteine proteinases for food digestion, expression of a single OC gene in potato exhibited a minimal or no effect on CPB fitness traits. The aim of this study was to examine the effect of coexpressed OCI and OCII in potato （Solanum tuberosum L.） cultivars Desiree, Draga6evka and Jelica on CPB larvae. Growth parameters, consumption rates and food utilization, as well as activity of proteases of CPB larvae were assayed. Second and third instar larvae fed on transformed leaves molted earlier and had higher relative growth and consumption rates than larvae fed on nontransformed leaves, while efficiency of food utilization was unaffected. In contrast, fourth instar maximum weight gain and amount of leaves consumed were about 20% lower for the larvae fed on transgenic potato. Analysis of total protease activity of third instar larvae revealed reduction in overall proteolytic activity measured by azocasein hydrolysis, accompanied with inhibition ofcysteine proteinase activity 24 h after ingestion of potato leaves expressing OCI and OCII. However, after long-term feeding on transformed leaves proteolytic activities of larvae became similar to the controls. Although feeding on OCI/OCII leaves did not affect larval survival, coexpression of OC genes reduced the development time and thus significantly decreased plant damage caused by CPB larvae.

关键词： Colorado potato beetle gene stacking oryzacystatin I and II proteinase inhibitors Solanum tuberosum L,

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