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Heterosis in age-specific selected populations of a seed beetle： Sex differences in longevity and reproductive behavior

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Insect Science 2015年第2期22卷 295-309页

作者： Biljana Stojkovic Mirko Dordevia jelena jankovic Uros Savkovic Nikola Tucic Department of Evolutionary Biology Institute for Biological Research 'Sinisa Stankovie' University of Belgrade Institute of Zoology Faculty of Biology University of Belgrade Belgrade Serbia

We tested mutation accumulation hypothesis for the evolution of senescence using short-lived and long-lived populations of the seed-feeding beetle, Acanthoscelides obtectus （Say）, obtained by selection on early- and late-life for many generations. The expected consequence of the mutation accumulation hypothesis is that in short-lived pop- ulations, where the force of natural selection is the strongest early in life, the late-life fitness traits should decline due to genetic drift which increases the frequency of mutations with deleterious effects in later adult stages. Since it is unlikely that identical deleterious mutations will increase in several independent populations, hybrid vigor for late-life fit- ness is expected in offspring obtained in crosses among populations selected for early-life fitness traits. We tested longevity of both sexes, female fecundity and male reproductive behavior for hybrid vigor by comparing hybrid and nonhybrid short-lived populations. Hybrid vigor was confirmed for male virility, mating speed and copulation duration, and longevity of both sexes at late ages. In contrast to males, the results on female fecundity in short-lived populations did not support mutation accumulation as a genetic mechanism for the evolution of this trait. Contrary to the prediction of this hypothesis, male mating ability indices and female fecundity in long-lived populations exhibited hybrid vigor at all assayed age classes. We demonstrate that nonhybrid long-lived populations diverged randomly regarding female and male reproductive fitness, indicating that sexually antag- onistic selection, when accompanied with genetic drift for female fecundity and male virility, might be responsible for overriding natural selection in the independently evolving long-lived populations.

关键词： ageing antagonistic selection drift experimental evolution inbreeding depression mutation accumulation

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耶莲娜·扬科维奇狂欢猫

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摄影之友 2023年第2期 78-87页

作者：健一 jelena jankovic(图) 不详

《狂欢猫》是一个通过拍摄肖像照片作为视觉识别实验而创建的项目。这些照片来自商业拍摄,经典的肖像变成了没有身份的剪影,面目全非的神秘人物具有神秘的意义。

关键词：视觉识别肖像狂欢照片拍摄猫

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Gender Differences in Acute Cadmium-Induced Systemic Inflammation in Rats

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Biomedical and Environmental Sciences 2009年第1期22卷 1-7页

作者： MILENA KATARANOVSKI SRDJA jankovic DRAGAN KATARANOVSKI jelena STOIC DESA BOGOJEVIC Department of Ecology Institute for Biological Research"Sinia Stankovi"Bulevar Despota Stefana 14211060 BelgradeSerbia Department of Molecular Biology Institutefor Biological Research"Sinia Stankovi"Bulevar Despota Stefana 14211060 BelgradeSerbia

Objective To examine the presence of gender differences in pro-inflammatory potential of cadmium in rats by comparing systemic inflammatory response to acute cadmium intoxication in animals of the two sexes. Methods Basic aspects of this response were evaluated, including plasma levels of inflammatory cytokines tumor necrosis factor （TNF） and interleukin-6 （IL-6） and of major rat acute phase protein alpha 2-macroglobulin （alpba2-M）, as soluble indicators of inflammation, and the number and activity of peripheral blood leukocytes, as cellular indicators of inflammation. Results Differential increases of IL-6 and alpha 2-M （higher in males than in females） in peripheral blood cell counts and types （leukocytosis and shift in the ratio of granulocytes to lymphocytes more pronounced in males vs females） and in levels of neutrophil priming （higher in males vs females） were noted. Conclusion The data document a more intense inflammatory response to cadmium administration in males. The sex differences in inflammatory effects of cadmium might be taken into consideration in studying the toxicity of this heavy metal.

关键词： Cadmium Sex Rats Inflammation

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Giant pseudoaneurysm of the splenic artery within walled of pancreatic necrosis on the grounds of chronic pancreatitis

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Hepatobiliary & Pancreatic Diseases International 2021年第1期20卷 87-89页

作者： Milica Mitrovic Jovanovic Dusan Saponjski Aleksandra Djuric Stefanovic Aleksandra jankovic Stefan Milosevic Katarina Stosic Djordje Knezevic jelena Kovac Department of Abdominal Radiology Center for Radiology and MRIClinical Center of SerbiaBelgradeSerbia Faculty of Medicine University of BelgradeBelgradeSerbia Clinic for Digestive Surgery–First Surgical Clinic Clinical Center of SerbiaBelgradeSerbia

Chronic pancreatitis is a long-standing inflammation of the pancreas,characterized by progressive inflammatory and fibrotic changes,resulting in permanent structural damage of pancreatic parenchyma[1].Pancreatitis(chronic or acute)is the primary risk factor for pseudo-splenic artery aneurysms,along with pancreatic pseudocysts and *** the disease progresses,patients with chronic pancreatitis may develop complications due to exocrine and endocrine pancreatic functional loss,such as fat malabsorption with steatorrhea,glucose intolerance,and ultimately diabetes mellitus[1,2].Furthermore,severe pancreatic inflammation can cause weakening of vessel walls,with subsequent formation of arterial *** artery is the most commonly affected visceral artery[2,3].Liver cirrhosis,portal hypertension,liver transplantation,atherosclerosis,hypertension,pregnancy and multiparity are main risk factors for true splenic artery aneurysms[2].Rupture and intraperitoneal bleeding is the cause of death in 30%−50%of ***,prompt diagnosis and appropriate treatment are of great clinical importance[4,5].Herein,we present a case of a giant splenic artery pseudoaneurysm within a walled of necrosis involving pancreatic parenchyma,as a complication of long standing chronic pancreatitis.

关键词： pancreatitis aneurysm inflammation

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