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Open Journal of Inorganic Chemistry 2016年第2期6卷 146-154页

作者： Jennifer d. Conner Wathsala Medawala Madison T. Stephens William H. Morris Joseph E. deweese Patrick L. Kent jeffery J. Rice Xiaohua Jiang Edward C. Lisic department of Chemistry Tennessee Technological University Cookeville TN USA department of Pharmaceutical Sciences Lipscomb University Nashville TN USA department of Biochemistry Vanderbilt University Nashville TN USA department of Chemical Engineering Tennessee Technological University Cookeville TN USA

The focus of this research is on the study of a series of copper (II) benzoylpyridine thiosemicarbazone complexes. Of the six benzoylpyridine thiosemicarbazone ligands used in this study, two are reported for the first time;2-benzoylpyridine tert-butyl thiosemicarbazone (BZP-tBTSC), and 2-benzoylpyridine benzyl thiosemicarbazone (BZP-BzTSC). Once characterized by NMR, melting point, and MS, these mono-anionic tridentate ligands were then reacted with Cu2+ to form the new square planar metal complexes [Cu(BZP-tBTSC)Cl] and [Cu(BZP-BzTSC)Cl]. All of the copper complexes display marked inhibition of human topoisomerase IIα. The [Cu(BZP-tBTSC)Cl] complex shows marked activity against human breast cancer cell lines.

关键词： Topoisomerase IIα Alpha-(N)-Heterocyclic Thiosemicarbazones Breast Cancer Cells

Riemann-Lebesgue引理的一些推广

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数学译林 2020年第1期39卷 93-96,80页

作者： Ovidiu Costin Neil Falkner jeffery d.McNeal 陆柱家(译) 陆昱(校) 不详

我们提出Riemann-Lebesgue(黎曼-勒贝格)引理的几个推广,我们的方法展现了Riemann Lebesgue引理中消去的作用.

关键词： Riemann 勒贝格黎曼引理消去推广

Measurement of Cotton Transpiration

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Agricultural Sciences 2018年第10期9卷 1299-1316页

作者： Robert J. Lascano jeffery T. Baker Paxton Payton dennis C. Gitz III James R. Mahan Timothy S. Goebel Wind Erosion and Water Conservation Research Cropping Systems Research Laboratory USDA-ARS Lubbock TX USA Plant Stress Germplasm development Research Cropping Systems Research Laboratory USDA-ARS Lubbock TX USA

There are a few field methods available to directly measure water evapotranspiration (ET) along with its two components, evaporation from the soil (E) and from the crop (T). One such technique that measures T, uses sensors to calculate the sap flow (F) of water through the plant stem and is based on the conservation of mass and energy, i.e., the stem heat balance method. This instrument consists of a flexible heater that is wrapped around the plant stem with temperature sensors to measure the difference in temperature of F below and above the heater. This is a null method, where all inputs and outputs are known and the calculated F is a direct measure of T. This method has been used to measure T in a variety of crops, including cotton, grapes, olive trees, soybean, ornamental and horticultural crops. A new version of the EXO-SkinTM is the Stem Gauge dual Channel design (SGdCTM), which was commercially introduced and had a radically new design resulting in a different energy balance, compared to the original design, which needed experimental verification. An initial evaluation was done with potted cotton (Gossypium hirsutum, L.) plants in a greenhouse experiment showing that values of cotton-T measured with the new sensor were accurate;however, this comparison was limited to daily T T in the 2 - 7 mm/d range, representative of the semiarid Texas High Plains. For this purpose, cotton was planted on 12 June 2017 on a 1000 m2 plot in a soil classified in the Amarillo series at the facilities of the USdA-ARS, Lubbock, TX. For a period of 15 days, 2 to 16 Sep 2017, we measured hourly cotton-T with the new sensors and with portable growth chambers (0.75 m × 1 m cross-section, and 1 m height) where water vapor flux was measured at a 10 Hz frequency using an infrared gas analyzer. We used three chambers and, in each chamber, the new sensors were installed on four cotton plants. We used linear regression analysis to compare hourly and daily values of cotton-T measured with th

关键词： Stem Flow Gauge Growth Chamber Water Use Irrigation Evaporation Field Test

局部缓释IUdR治疗恶性星形细胞瘤实验研究(英文)

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中华神经外科疾病研究杂志 2005年第4期4卷 293-298页

作者：马晓东 Jerry R.Williams Larry E.dillehay jeffery A Williams 中国人民解放军总医院神经外科北京100853 美国约翰霍普金斯大学肿瘤系放射肿瘤研究室放射生物学实验室美国马里兰州巴尔地摩21287 美国约翰霍普金斯医院神经外科

目的研究脑局部缓释125碘标记的5-碘脱氧尿苷(IUdR)的作用。方法为了控制释放125碘-IUdR,合成了25μCi的羧基苯氧丙烷:癸二酸(PCPPSA)(2080)125碘-IUdR聚合体。体外将合成的三聚体缓释剂(10mgPCPPSA)置于37℃磷酸盐缓冲溶液(PBS)中孵育... 详细信息

目的研究脑局部缓释125碘标记的5-碘脱氧尿苷(IUdR)的作用。方法为了控制释放125碘-IUdR,合成了25μCi的羧基苯氧丙烷:癸二酸(PCPPSA)(2080)125碘-IUdR聚合体。体外将合成的三聚体缓释剂(10mgPCPPSA)置于37℃磷酸盐缓冲溶液(PBS)中孵育不同时间后移出溶剂并置换为新的PBS,将移出液于放射计数器上测量数值。在体研究采用雄性裸鼠(6周)颅内接种U251人恶性星形细胞瘤及皮下接种对比研究。将颅内荷瘤鼠瘤腔内及皮下接种肿瘤组织内分别应用三聚体缓释剂及空白缓释剂,于不同时间分别测量动物头颅及皮下结节的放射活性,间接定量研究缓释状况;采血了解全身代谢情况。对于多聚磷酸酯(PPE)缓释剂研究采用皮下肿瘤结节内局部应用并测量其缓释的方法,放射自显影研究及全身不同器官缓释剂的吸收代谢研究采用接种后2、4和8d收集标本,分别行切片放射自显影和器官放射活性测定。结果体内和体外研究均显示PCPP:SA缓释剂对125碘-IUdR的控制性释放作用,尤其在体研究分别显示颅内和皮下接种的肿瘤组织对标记的IUdR的释放程度存有极大的差异,提示颅内局部应用的优越性。放射自显影定性研究显示了随距离的增加被标记的IUdR的递减趋势,为确定缓释剂施放部位和间距提供了参考数据。各主要脏器放射性测定的结果显示早期小肠内放射性较高,其次为脾脏,提示IUdR主要的代谢渠道,为处理应用其而可能引发的其他脏器损害或作用提供了线索。结论放射标记的IUdR缓释剂主要集中在接种部位且缓释作用确切。

关键词：生物降解缓释剂 5-碘脱氧尿苷放射标记 ^125I 胶质瘤

口服氮-氨甲酰谷氨酸补饲增加仔猪骨骼肌中的蛋白质合成

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饲料与畜牧（新饲料） 2012年第12期 12-16页

作者： Jason W.Frank jeffery Escobar Hanh V.Nguyen 赵颖不详中国农业大学动物科技学院

文章研究了补饲氮-氨甲酰谷氨酸(N-Carbamylglutamate,NCG,一种模拟内源性氮-乙酰谷氨酸,合成精氨酸的激活剂)提高哺乳仔猪的生长率的潜在机制。试验选取体重接近、性别相同的2组仔猪进行口服试验,每12h向日粮中分别添加0mg/kg(对照组)... 详细信息

文章研究了补饲氮-氨甲酰谷氨酸(N-Carbamylglutamate,NCG,一种模拟内源性氮-乙酰谷氨酸,合成精氨酸的激活剂)提高哺乳仔猪的生长率的潜在机制。试验选取体重接近、性别相同的2组仔猪进行口服试验,每12h向日粮中分别添加0mg/kg(对照组)和50mg/kgNCG(试验组),试验期为7d。试验仔猪(n=32,BW=3kg)禁食7d并进行试验前处理。整夜禁食后,分别在0min和60min饲喂仔猪NCG和水(对照组)。之后分别在第0min和60min灌服试验组仔猪含NCG的母乳。在第60min,给仔猪灌服[3H]水浸剂量的苯丙氨酸,并在第90min宰杀,用以测定组织蛋白的合成。与对照组相比,NCG处理组的仔猪体重在7d内增加了28%(P<0.001),与禁食的仔猪相比,未禁食仔猪的背最长肌、腓肠肌、十二指肠的蛋白质合成速率均较高(P<0.001)。与对照组相比,NCG试验处理组仔猪背最长肌和腓肠肌的蛋白质合成速率分别提高了30%(P=0.05)和21%(P=0.068)。同时,补饲NCG的仔猪血浆中精氨酸和生长激素的浓度高于对照组。结果显示,补饲氮-氨甲酰谷氨酸可以提高血浆中精氨酸和生长激素水平,促进哺乳仔猪生长率和肌肉蛋白质合成的增加。

关键词：氮-氨甲酰谷氨酸仔猪骨骼肌蛋白质合成

日粮中添加莫能菌素对奶牛结肠内容物中细菌群落的影响

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中国畜牧兽医 2011年第4期38卷 172-172页

作者： jeffery A 姜雅慧（摘译）臧长江（校）

试验旨在研究聚醚类离子载体抗生素莫能菌素对奶牛结肠内容物中细菌群落的影响。试验动物为6头泌乳奶牛，莫能菌素的添加量为600mg／d，对照组日粮中不添加莫能菌素，试验期为3个月。试验期每月采集固体废物用16SrRNA序列分析细菌群落... 详细信息

试验旨在研究聚醚类离子载体抗生素莫能菌素对奶牛结肠内容物中细菌群落的影响。试验动物为6头泌乳奶牛，莫能菌素的添加量为600mg／d，对照组日粮中不添加莫能菌素，试验期为3个月。试验期每月采集固体废物用16SrRNA序列分析细菌群落的变化。样品中共检测到6912个16SrRNA基因，其中包含处理组和对照组中各345和315个待分析的个体（OTUs）。

关键词：奶牛排泄物莫能菌素 16S rRNA

The Tianlai Cylinder Pathfinder array: System functions and basic performance analysis

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Science China(Physics,Mechanics & Astronomy) 2020年第12期63卷 2-28页

作者： JiXia Li ShiFan Zuo FengQuan Wu YouGang Wang JuYong Zhang ShiJie Sun Yidong Xu ZiJie Yu Reza Ansari YiChao Li Albert Stebbins Peter Timbie YanPing Cong JingChao Geng Jie Hao QiZhi Huang JianBin Li Rui Li dongHao Liu YingFeng Liu Tao Liu John PMarriner ChenHui Niu Ue-Li Pen jeffery BPeterson HuLi Shi Lin Shu YaFang Song HaiJun Tian GuiSong Wang QunXiong Wang RongLi Wang WeiXia Wang Xin Wang KaiFeng Yu Jiao Zhang BoQin Zhu JiaLu Zhu XueLei Chen National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China Center for Astrophysics and department of Astronomy Tsinghua UniversityBeijing 100084China School of Mechanical Engineering Hangzhou Dianzi UniversityHangzhou 310018China IJC Lab CNRS/IN2P3&UniversitéParis-SaclayOrsay 91405France department of Physics and Astronomy University of the Western CapeBelville 7535Republic of South Africa Fermi National Accelerator Laboratory Batavia IL 60510-5011USA department of Physics University of Wisconsin MadisonMadison WI 53703USA The 54th Research Institute China Electronics Technology Group CorporationShijiazhuang 050051China Institute of Automation Chinese Academy of SciencesBeijing 100190China Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830001China Canadian Institute for Theoretical Astrophysics University of TorontoToronto M5S 3H8Canada department of Physics Carnegie Mellon UniversityPittsburgh PA 15213USA Center for Astronomy and Space Sciences China Three Gorges UniversityYichang 443002China School of Physics and Astronomy Sun Yat-sen UniversityGuangzhou 510297China College of Physics and Electronic Engineering Shanxi UniversityTaiyuan 030006China Center of High Energy Physics Peking UniversityBeijing 100871China

The Tianlai Cylinder Pathfinder is a radio interferometer array designed to test techniques for 21 cm intensity mapping in the post-reionization Universe,with the ultimate aim of mapping the large scale structure and measuring cosmological parameters such as the dark energy equation of *** of its three parallel cylinder reflectors is oriented in the north-south direction,and the array has a large field of *** the Earth rotates,the northern sky is observed by drift *** array is located in Hongliuxia,a radio-quiet site in Xinjiang,and saw its first light in September *** this first data analysis paper for the Tianlai cylinder array,we discuss the sub-system qualification tests,and present basic system performance obtained from preliminary analysis of the commissioning observations during *** show typical interferometric visibility data,from which we derive the actual beam profile in the east-west direction and the frequency band-pass *** describe also the calibration process to determine the complex gains for the array elements,either using bright astronomical point sources,or an artificial on site calibrator source,and discuss the instrument response stability,crucial for transit *** on this analysis,we find a system temperature of about 90 K,and we also estimate the sensitivity of the array.

关键词： interferometer radio astronomy neutral hydrogen cosmology dark energy

FAIR Principles:Interpretations and Implementation Considerations

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data Intelligence 2020年第1期2卷 10-29,293-302,322页

作者： Annika Jacobsen Ricardo de Miranda Azevedo Nick Juty dominique Batista Simon Coles Ronald Cornet Melanie Courtot Merce Crosas Michel dumontier Chris T.Evelo Carole Goble Giancarlo Guizzardi Karsten Kryger Hansen Ali Hasnain Kristina Hettne Jaap Heringa Rob W.W.Hooft Melanie Imming Keith G.jeffery Rajaram Kaliyaperumal Martijn GKersloot Christine R.Kirkpatrick Tobias Kuhn Ignasi Labastida Barbara Magagna PeterMcQuilton Natalie Meyers Annalisa Montesanti Mirjam van Reisen Philippe Rocca-Serra Robert Pergl Susanna-Assunta Sansone Luiz Olavo Bonino da Silva Santos Juliane Schneider George Strawn Mark Thompson Andra Waagmeester Tobias Weigel Mark d.Wilkinson Egon L.Willighagen Peter Wittenburg Marco Roos Barend Mons Erik Schultes Leiden University Medical Center Leiden2333 ZAThe Netherlands Institute of data Science Maastricht UniversityUniversiteitssingel 60Maastricht 6229 ERThe Netherlands department of Computer Science The University of ManchesterOxford RoadManchester M139PLUK Oxford e-Research Centre Department of Engineering SciencesUniversity of OxfordOxford OX13PJUK School of Chemistry Faculty of Engineering and Physical SciencesUniversity of SouthamptonSO171BJUK Amsterdam UMC University of AmsterdamAmsterdam 1000 GGThe Netherlands European Bioinformatics Institute(EMBL-EBI) HinxtonCambridgeCB101SDUK Harvard University CambridgeMassachusetts 02138USA department of Bioinformatics–BiGCaT NUTRIMMaastricht UniversityMaastricht 6229 ERThe Netherlands Conceptual and Cognitive Modeling Research Group(CORE) Free University of Bozen-BolzanoBolzano 39100Italy Aalborg University Aalborg DK-9220Denmark Insight Centre for data Analytics National University of Ireland GalwayH91 TK33Ireland Centre for digital Scholarship Leiden University LibrariesLeiden2333 ZAThe Netherlands department of Computer Science Vrije Universiteit AmsterdamDe Boelelaan 11051081 HV AmsterdamThe Netherlands dutch Techcentre for Life Sciences(dTL) UtrechtThe Netherlands SURF Utrecht 3511 EPThe Netherlands Keith G jeffery Consultants FaringdonUK Castor EdC Paasheuvelweg 25Wing 5D1105 BPAmsterdamThe Netherlands San diego Supercomputer Center University of California San DiegoLa JollaCalifornia 92093USA Learning and Research Resources Centre(CRAI) Universitat de Barcelona08007 BarcelonaSpain Environment Agency Austria A-1090 ViennaAustria University of Notre dame 75004 ParisFrance Health Research Board(HRB) Dublin 2DO2 H638Ireland Liacs Institute of Advanced Computer Science Leiden University2311 GJ LeidenThe Netherlands Czech Technical University in Prague Faculty of Information Technology(FIT CTU)16000 Prague 6Czech Republic GO FAIR International Support&Coordination Office(GFISCO) LeidenThe Netherlands Harvard Catalys

The FAIR principles have been widely cited,endorsed and adopted by a broad range of stakeholders since their publication in *** intention,the 15 FAIR guiding principles do not dictate specific technological implementations,but provide guidance for improving Findability,Accessibility,Interoperability and Reusability of digital *** has likely contributed to the broad adoption of the FAIR principles,because individual stakeholder communities can implement their own FAIR ***,it has also resulted in inconsistent interpretations that carry the risk of leading to incompatible ***,while the FAIR principles are formulated on a high level and may be interpreted and implemented in different ways,for true interoperability we need to support convergence in implementation choices that are widely accessible and(re)-*** introduce the concept of FAIR implementation considerations to assist accelerated global participation and convergence towards accessible,robust,widespread and consistent FAIR *** self-identified stakeholder community may either choose to reuse solutions from existing implementations,or when they spot a gap,accept the challenge to create the needed solution,which,ideally,can be used again by other communities in the ***,we provide interpretations and implementation considerations(choices and challenges)for each FAIR principle.

关键词： FAIR guiding principles FAIR implementation FAIR convergence FAIR communities choices and challenges

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岩石分析的化学方法

分析试验室 1982年第1期 43-43页

作者：柳宸 P.G.jeffery d.Hutchison

1981年 Pergamon 出版社出版的《岩石分析的化学方法》(第3版)共包括48章。前四章详细论述了岩石分析的一般特性:岩石物料的组成和取样、破碎及研磨、样品沾污源等一般性问题和特点(第一章);关于试样分解方法的详尽讨论(第二章);岩石分... 详细信息

1981年 Pergamon 出版社出版的《岩石分析的化学方法》(第3版)共包括48章。前四章详细论述了岩石分析的一般特性:岩石物料的组成和取样、破碎及研磨、样品沾污源等一般性问题和特点(第一章);关于试样分解方法的详尽讨论(第二章);岩石分析的经典方法,例如主要组分和常见组分的一系列基本常规分析方法(第三章);系统完整地描述岩石样品的快速分析法,读者能够从中得到一个清晰全面的认识(第四章)。另外44章则是更深入细致地介绍单一元素或性质相类似的成组元素(如碱金属;钪、钆和稀土;锆和铪;钽和铌;氯、

关键词：岩石分析岩石样品常规分析方法一般性问题成组分解方法三章

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MLR的结果与尸肾移植物存活和输血无关

中华器官移植杂志 1986年第2期7卷 85-85页

作者： jeffery JR 周平

已证实在活体亲属供者中,混合淋巴细胞培养反应(MLR)较弱或阴性,移植物存活较好,但对尸肾移植却有争议.术前输血之所以可以延长移植物存活的机理还不太清楚.本文报告65例尸肾受者(R)分别与其特异的供者(d)和多个供者混合的第3组细胞(P)... 详细信息

已证实在活体亲属供者中,混合淋巴细胞培养反应(MLR)较弱或阴性,移植物存活较好,但对尸肾移植却有争议.术前输血之所以可以延长移植物存活的机理还不太清楚.本文报告65例尸肾受者(R)分别与其特异的供者(d)和多个供者混合的第3组细胞(P)间的单向和双向:MLR 5天的结果:术前输过血的尸肾受者,MLR结果与移植物存活无关;第1次移植物失败又未输过血的受者,与移植成功者比较,R-P间的MLR反应明显较强,而R-d间的MLR无明显增强.作者测定了61例尸肾移植受者和52例即将接受肾移植的受者与P的单向MLR,显示其反应程度与输血次数、末次输血时间及细胞毒抗体产生高峰等均无关.

关键词：移植物存活尸肾移植混合淋巴细胞输血活体亲属供者肾移植受者培养反应抗体产生反应程度细胞毒成功者增强阴性显示机理测定报告