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How to integrate hemodynamic variables during resuscitation of septic shock?

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Journal of Intensive Medicine 2023年第2期3卷 131-137页

作者： jean.louis Teboul Service de Médecine Intensive-Réanimation Hopital de BicêtreGHU AP-HPUniversitéParis-SaclayParis 94270France

Resuscitation of septic shock is a complex issue because the cardiovascular disturbances that characterize septic shock vary from one patient to another and can also change over time in the same patient. Therefore, different therapies (fluids, vasopressors, and inotropes) should be individually and carefully adapted to provide personalized and adequate treatment. Implementation of this scenario requires the collection and collation of all feasible information, including multiple hemodynamic variables. In this review article, we propose a logical stepwise approach to integrate relevant hemodynamic variables and provide the most appropriate treatment for septic shock.

关键词： Lactate Capillary refill time Central venous oxygen saturation Veno-arterial carbon dioxide gap Transpulmonary thermodilution

Quantitative Detection of Blood Vessel Structures in MRI by Using 3-D Geometrical Moments

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Chinese Science Bulletin 1994年第9期39卷 785-789页

作者：罗立民谢筱华鲍旭东 jean.louis Coatrieux Department of Biology and Medical Engineering Southeast University Nanjing 210018 PRC Laboratoire Traitement du Signal et de L'Image University of Rennes-Ⅰ35042 RennesFrance

The quantitative analysis of three-dimensional (3-D) human blood vessel structuresplays a very important role in the clinical diagnosis. The conventional X-ray approacheshave some shortcomings, such as the need to make use of a dye-product and basisprojective-integrative rule for the image formation. On the one hand, the patient hasto suffer a great radiation dose, and a registration process is also often needed to cor-rect the displacement bias between the images due to the patient’s movements. On

关键词： blood vessel moments quantitative detection.

Balance control during gait initiation: State-of-the-art and research perspectives

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World Journal of Orthopedics 2017年第11期8卷 815-828页

作者： Eric Yiou Teddy Caderby Arnaud Delafontaine Paul Fourcade jean.louis Honeine Laboratoire CIAMS Université Paris-Sud Université Paris-Saclay Laboratoire CIAMS Université d’Orléans Laboratoire IRISSE UFR des Sciences de l’Homme et de l’Environnement Université de la Réunion Ecole Nationale de Kinésithérapie et Rééducation Department of Public Health Experimental and Forensic Medicine University of Pavia

It is well known that balance control is affected by aging, neurological and orthopedic conditions. Poor balance control during gait and postural maintenance are associated with disability, falls and increased mortality. Gait initiation-the transient period between the quiet standing posture and steady state walking-is a functional task that is classically used in the literature to investigate how the central nervous system(CNS) controls balance during a whole-body movement involving change in the base of support dimensions and center of mass progression. Understanding how the CNS in able-bodied subjects exerts this control during such a challenging task is a prerequisite to identifying motor disorders in populations with specific impairments of the postural system. It may also provide clinicians with objective measures to assess the efficiency of rehabilitation programs and better target interventions according to individual impairments. The present review thus proposes a state-of-the-art analysis on:(1) the balance control mechanisms in play during gait initiation in able bodied subjects and in the case of some frail populations; and(2) the biomechanical parameters used in the literature to quantify dynamic stability during gait initiation. Balance control mechanisms reviewed in this article included anticipatory postural adjustments, stance leg stiffness, foot placement, lateral ankle strategy, swing foot strike pattern and vertical center of mass braking. Based on this review, the following viewpoints were put forward:(1) dynamic stability during gait initiation may share a principle of homeostatic regulation similar to most physiological variables, where separate mechanisms need to be coordinated to ensure stabilization of vital variables, and consequently; and(2) rehabilitation interventions which focus on separate or isolated components of posture, balance, or gait may limit the effectiveness of current clinical practices.

关键词： Balance control Anticipatory postural adjustments Leg stiffness Foot placement Lateral ankle strategy Foot strike pattern Vertical center of mass braking Dynamic stability Gait initiation Biomechanics

Hierarchical networks of food exchange in the black garden ant Lasius niger

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Insect Science 2021年第3期28卷 825-838页

作者： Martin Quque Olivier Bles Annaelle Benard Amelie Heraud Bastien Meunier Frangois Criscuolo jean.louis Deneubourg Cedric Sueur CA/RS IPHCUniversite de StrasbourgStrasbourgUMR718France Centre for Nonlinear Phenomena and Complex Systems(Cenoli)-CP 231 Universite libre de Bruxelles(ULB)BruxellesBelgium Universite de Bourgogne Franche-Comte DijonFrance Universite de Rennes 1 RennesFrance Institut Universitaire de France ParisFrance

In most eusocial insects,the division of labor results in relatively few individuals foraging for the entire ***,the survival of the colony depends on its efficiency in meeting the nutritional needs of all its ***,we characterize the network topology of a eusocial insect to understand the role and centrality of each caste in this network during the process of food *** constructed trophallaxis networks from 34 food-exchange experiments in black garden ants(Lasius niger).We tested the influence of brood and colony size on(i)global indices at the network level(i.e.,efficiency,resilience,centralization,and modularity)and(ii)individual values(i.e.,degree,strength,betweenness,and the clustering coefficient).Network resilience,the ratio between global efficiency and centralization,was stable with colony size but increased in the presence of broods,presumably in response to the nutritional needs of *** metrics highlighted the major role of foragers in food *** addition,a hierarchical clustering analysis suggested that some domestics acted as intermediaries between foragers and other *** appeared to be hierarchical rather than random or centralized exclusively around ***,our results suggested that networks emerging from social insect interactions can improve group performance and thus colony fitness.

关键词： insects network evolution self-organization social evolution social network analyses

A Revised Interpretation of the Thermodynamic Theory Including the Einstein Mass-Energy Relation E= mc2

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Journal of Applied Mathematics and Physics 2020年第3期8卷 392-405页

作者： jean.louis Tane Formerly with the Department of Geology University of Grenoble Grenoble France

Thermodynamics being among the most synthetic theories of physics and the mass-energy relation E = mc2 among the most general equations of science, it is somewhat surprising that this latter is not explicitly present in the laws of thermodynamics. Coupling this observation with the conceptual difficulties often felt in learning thermodynamics leads to the idea that both situations may have the same cause. On the basis of these clues, this paper is intended to provide complementary arguments to a hypothesis already presented. It consists of showing the existence of an imperfect compatibility between the conventional formulations of the first and second laws of thermodynamics and suggesting the need of the mass-energy relation to solving the problem.

关键词： Thermodynamics Entropy Energy Einstein’s Mass-Energy Relation Relativity

The Reasons Suggesting a Close Link between Thermodynamics and Relativity

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Journal of Applied Mathematics and Physics 2017年第9期5卷 1710-1719页

作者： jean.louis Tane Formerly with the Department of Geology University Joseph Fourier Grenoble France

Since the advent of relativity, it is widely accepted that the law of conservation of energy must include the energy created by disintegration of matter, or converted into matter. The aim of the present paper deals wi... 详细信息

关键词： Thermodynamics Relativity Energy Entropy Einstein’s Mass-Energy Relation Gravitation

An Extended Interpretation of the Concept of Entropy Opening a Link between Thermodynamics and Relativity

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Natural Science 2014年第7期6卷 503-513页

作者： jean.louis Tane Formerly with the Department of Geology University Joseph Fourier Grenoble France

It is well known that thermodynamics raises conceptual difficulties. Far to be limited to students having to learn the subject, this impression is sometimes mentioned by specialists themselves who confess not being totally sure of the consistency of the thermodynamic theory, despite the fact that its practical usefulness is indisputable. The present paper deals with this interesting question and leads to the idea that there is an imperfect convergence between the way of using the thermodynamic tool and the way of understanding its significance. Illustrated by a very simple example, the discussion can be followed by every scientist having the fundamental basis in thermodynamics. The suggested hypothesis is that the Einstein mass-energy relation is closely associated to the concept of entropy, opening a link between thermodynamics and relativity.

关键词： Thermodynamics Reversibility Irreversibility Energy Entropy Einstein’s Mass-Energy Relation Relativity Gravitation

微滤处理对Mozzarella干酪液相组成及微观结构的影响

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哈尔滨工业大学学报 2009年第8期41卷 50-55页

作者：董晶莹马莺陈历俊 jean.louis Maubois 哈尔滨工业大学食品科学与工程学院哈尔滨150080 北京三元食品股份有限公司技术中心北京100085 Laboratoire de Recherches de Technologie LaitiSre INRA 65 rue de Saint Brieuc 35042 Rennes Cedex France

为研究微滤处理对Mozzarella干酪的影响,采用液压压榨技术及扫描电镜技术对其4℃,10d成熟期间液相含量及微观结构进行研究.对照组及微滤组Mozzarella干酪的理化成分(除水分、钙、磷外)差异不显著(p>0.05).两组干酪的液相含量/水分含量... 详细信息

为研究微滤处理对Mozzarella干酪的影响,采用液压压榨技术及扫描电镜技术对其4℃,10d成熟期间液相含量及微观结构进行研究.对照组及微滤组Mozzarella干酪的理化成分(除水分、钙、磷外)差异不显著(p>0.05).两组干酪的液相含量/水分含量随着成熟期的延长而减少,液相部分的蛋白质含量微滤组低于对照组,而缓冲能力高于对照组.扫描电镜结果显示,随着成熟期的进行,蛋白质基质吸收游离水分,液相通道变窄.对照组Mozzarella干酪的蛋白质基质更加平滑和均一,通道更加多孔等微观现象反应出微滤浓缩对干酪的影响源于干酪用乳的不同.

关键词：微滤 Mozzarella干酪液相微观结构扫描电镜

Epidural anesthesia improves pancreatic perfusion and decreases the severity of acute pancreatitis

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World Journal of Gastroenterology 2015年第43期21卷 12448-12456页

作者： Samira M Sadowski Axel Andres Philippe Morel Eduardo Schiffer jean.louis frossard Alexandra Platon Pierre-Alexandre Poletti Leo Bühler Department of Visceral and Transplantation Surgery University Hospitals of Geneva Department of Anesthesiology University Hospital Geneva Department of Gastroenterology University Hospital Geneva Department of Radiology University Hospital Geneva

AIM: To study the safety of epidural anesthesia(EA),its effect on pancreatic perfusion and the outcome of patients with acute pancreatitis(AP).METHODS: From 2005 to August 2010,patients with predicted severe AP [Ranson score ≥ 2,C-reactive protein > 100 or necrosis on computed tomography(CT)] were prospectively randomized to either a group receiving EA or a control group treated by patientcontrolled intravenous analgesia. Pain management was evaluated in the two groups every eight hours using the visual analog pain scale(VAS). Parameters for clinical severity such as length of hospital stay,use of antibiotics,admission to the intensive care unit,radiological/clinical complications and the need for surgical necrosectomy including biochemical data were recorded. A CT scan using a perfusion protocol was performed on admission and at 72 h to evaluate pancreatic blood flow. A significant variation in blood flow was defined as a 20% difference in pancreatic perfusion between admission and 72 h and was measured in the head,body and tail of the ***: We enrolled 35 patients. Thirteen were randomized to the EA group and 22 to the control group. There were no differences in demographic characteristics between the two groups. The Balthazar radiological severity score on admission was higher in the EA group than in the control group(mean score 4.15 ± 2.54 vs 3.38 ± 1.75,respectively,P = 0.347) and the median Ranson scores were 3.4 and 2.7 respectively(P = NS). The median duration of EA was 5.7 d,and no complications of the epidural procedure were reported. An improvement in perfusion of the pancreas was observed in 13/30(43%) of measurements in the EA group vs 2/27(7%) in the control group(P = 0.0025). Necrosectomy was performed in 1/13 patients in the EA group vs 4/22 patients in the control group(P = 0.63). The VAS improved during the first ten days in the EA group compared to the control group(0.2 vs 2.33,P = 0.034 at 10 d). Length of stay and mortality were not

关键词： Severe acute pancreatitis Epidural anes thesia Pan