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Surgical Science 2014年第2期5卷 70-73页

作者： Bertrand Saint-Lebes Celine Dubuis sebastien Deglise Francois Saucy jean-Marc Corpataux Department of Vascular Surgery University HospitalToulouseFrance Department of Vascular Surgery Centre Hospitalier Universitaire Vaudois(CHUV)University HospitalLausanneSwitzerland

Patients on chronic hemodialysis (HD) required efficient arterio-venous access. Different types of vascular access are commonly used, such as native arteriovenous (AV) fistula, prosthetic AV graft, central venous catheter, or temporary and tunnelled cuffed catheters. Vascular access—related morbidity remains the major issue for patients requiring long-term therapy. Vascular access infection constitutes the most challenging and life-threatening complication of vascular access and causes significant morbidity, loss of access and mortality. Vascular access infection is defined as local signs at the vascular access site or a positive blood culture with no know source other than the vascular access. The critical issue in the management of AV graft infection is the need to remove the infection and to maintain HD access with reduced morbidity. The diagnosis of infected AV graft is not always easy, especially with low-grade infection or atypical presentation. Fluorodeoxyglucose positron emission tomography (FDG-PET) is an imaging method that uses a radioactively labelled tracer (18 fluorodeoxy glucose) which is taken up by tissue with high metabolic activity, such as neoplastic and inflammatory lesions. FDG-PET has been proposed to visualise localisation of infection in patients with suspected prosthetic graft infection. We report a case of methicilin resistant staphylococcus aureus (MRSA) hemodialysis access infection without local inflammatory signs diagnosed on the PET-CT.

关键词： Hemodialysis Access Graft Infection PET-CT

The maximum likelihood identification method applied to insect morphometric data

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Zoological Systematics 2017年第1期42卷 46-58页

作者： jean-Pierre Dujardin sebastien Dujardin Dramane Kaba Soledad Santillan-Guayasamin Anita G.Villacis Sitha Piyaselakul Suchacla Sumruayphol Yudthana Samung Ronald Morales Vargas IRD UMR 177 IRD-CIRAD INTERTRYP Campus international de Baillarguet Montpellier France Ecole des Technologies Numdriques Appliquees Paris France Institut Pierre Riehet Institut National de Sante Publique Abidjan Cote d'Ivoire Center for Research on Health in Latin America School of Biological Sciences Pontifical Catholic University of Ecuador Quito Ecuador Av. 12 de Oetubre 1076y Roca Department of Anatomy Faculty of Medicine Siriraj Hospital Mahidol University Bangkok 10700 Thailand Department of Medical Entomology Faculty of Tropical Medicine Mahidol University Bangkok 10400 Thailand

To distinguish species or populations using morphometric data is generally processed through multivariate analyses, in particular the discriminant analysis. We explored another approach based on the maximum likelihood method. Simple statistics based on the assumption of normal distribution at a single variable allows to compute the chance of observing a particular data （or sample） in a given reference group. When data are described by more than one variable, the maximum likelihood （MLi） approach allows to combine these chances to find the best fit for the data. Such approach assumes independence between variables. The assumptions of normal distribution of variables and independence between them are frequently not met in morphometrics, but improvements may be obtained after some mathematical transformations. Provided there is strict anatomical correspondence of variables between unknown and reference data, the MLi classification produces consistent classification. We explored this approach using various input data, and compared validated classification scores with the ones obtained after the Mahalanobis distance-based classification. The simplicity of the method, its fast computation, performance and versatility, make it an interesting complement to other classification techniques.

关键词： Medical entomology morphometrics classification probability Mahalanobisdistance.

HACD1,a regulator of membrane composition and fluidity,promotes myoblast fusion and skeletal muscle growth

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分子细胞生物学报:英文版 2015年第5期7卷 429-440页

作者： Jordan Blondelle Yusuke Ohno Vincent Gache Stephane Guyot sebastien Storck Nicolas Blanchard-Gutton Ines Barthelemy Gemma Walmsley Anaelle Rahier Stephanie Gadin Marie Maurer Laurent Guillaud Alexandre Prola Arnaud Ferry Genevieve Aubin-Houzelstein jean Demarquoy Frederic Relaix Richard JPiercy Stephane Blot Akio Kihara Laurent Tiret Fanny Pilot-Storck Inserm IMRB U955-E1094000 CreteilFrance Universite Paris-Est Ecole nationale veterinaire d’Alfort(EnvA)94700 Maisons-AlfortFrance Universite Paris-Est Creteil Faculte de medecine94000 CreteilFrance Laboratory of Biochemistry Faculty of Pharmaceutical SciencesHokkaido UniversitySapporo 060-0812Japan Universite de Bourgogne UMR A 02.102 PAM-EPMBAgroSup Dijon21000 DijonFrance Institut Necker-Enfants Malades INSERM U1151-CNRS UMR 8253Sorbonne Paris CiteUniversite Paris DescartesFaculte de Medecine-Site Broussais75015 ParisFrance Comparative Neuromuscular Disease Laboratory Department of Clinical Sciences and ServicesRoyal Veterinary CollegeLondon NW10TUUK Therapie des maladies du muscle strie INSERM U974-CNRS UMR7215-UPMC UM76-Institut de Myologie Universite Pierre et Marie Curie-Universite Paris Descartes75000 ParisFrance Universite de Bourgogne Faculte des Sciences GabrielBio-PeroxIL21000 DijonFrance

The reduced diameter of skeletal myofibres is a hallmark of several congenital myopathies,yet the underlying cellular and molecular mechanisms remain *** this study,we investigate the role of HACD1/PTPLA,which is involved in the elongation of the very long chain fatty acids,in muscle fibre *** humans and dogs,HACD1 deficiency leads to a congenital myopathy with fibre size disproportion associated with a generalized *** of HACD1-deficient Labradors,Hacd1-knockout mice,and Hacd1-deficient myoblasts,we provide evidence that HACD1 promotes myoblast fusion during muscle development and *** further demonstrate that in normal differentiating myoblasts,expression of the catalytically active HACD1 isoform,which is encoded by a muscle-enriched splice variant,yields decreased lysophosphatidylcholine content,a potent inhibitor of myoblast fusion,and increased concentrations of≥C18 and monounsaturated fatty acids of *** lipid modifications correlate with a reduction in plasma membrane *** conclusion,we propose that fusion impairment constitutes a novel,non-exclusive pathological mechanism operating in congenital myopathies and reveal that HACD1 is a key regulator of a lipid-dependent muscle fibre growth mechanism.

关键词： centronuclear myopathy LPC MUFA PTPLA VLCFA

Small bowel entrapment and ureteropelvic junction disruption associated with L3 Chance fracture-dislocation

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World Journal of Clinical Cases 2016年第9期4卷 264-268页

作者： sebastien Pesenti Benjamin Blondel Alice Faure Emilie Peltier Franck Launay jean-Luc Jouve Pediatric Orthopaedics Hopital d'Enfants de la TimoneAix Marseille University Spine Unit Aix Marseille University Pediatric Surgery H?pital NordAix-Marseille University

Paediatric Chance fracture are rare lesions but often associated with abdominal injuries. We herein present the case of a seven years old patient who sustained an entrapment of small bowel and an ureteropelvic disruption associated with a Chance fracture and spine dislocation following a traffic accident. Initial X-rays and computed tomographic(CT) scan showed a Chance fracture with dislocation of L3 vertebra, with an incarceration of a small bowel loop in the spinal canal and a complete section of the left lumbar ureter. Paraplegia was noticed on the initial neurological examination. A posterior L2-L4 osteosynthesis was performed firstly. In a second time she underwent a sus umbilical laparotomy to release the incarcerated jejunum loop in the spinal canal. An end-toend anastomosis was performed on a JJ probe to suture the left injured ureter. One month after the traumatism, she started to complain of severe headaches related to a leakage of cerebrospinalis fluid. Three months after the traumatism there was a clear regression of the leakage. One year after the trauma, an anterior intervertebral fusion was done. At final follow-up, no neurologic recovery was noticed. In case of Chance fracture, all physicians should think about abdominal injuries even if the patient is asymptomatic. Initial abdominal CT scan and magnetic resonance imaging provide in such case crucial info for management of the spine and the associated lesions.

关键词： Chance fracture Uretero-pelvic disruption Small bowel injuries Seatbelt Dural tear

Popliteal Venous Pseudoaneurysm and Arteriovenous Fistula after Orthopedic Surgery

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World Journal of Cardiovascular Surgery 2013年第1期3卷 1-7页

作者： Bertrand Saint-Lebes Emilie Chastonay Olivier Borens Celine Dubuis sebastien Deglise Francois Saucy Herve Rousseau jean-Marc Corpataux Department of Thoracic and Vascular Surgery Lausanne University HospitalLausanneSwitzerland Department of Orthopaedic and Trauma Surgery Lausanne University HospitalLausanneSwitzerland Department of Vascular Interventional Radiology University HospitalToulouseFrance

Arthroscopically assisted reconstruction of the anterior cruciate ligament (LCA) is generally a safe and effective procedure with a low rate of vascular complications. We report on a case of a 33-year-old woman with a combined arteriovenous fistula (AVF) and venous popliteal aneurysm that developed 6 months after arthroscopic anterior cruciate ligament reconstruction. At clinical exam the patient presented with left popliteal and calf pain, a tender pulsatile mass posterior to her left knee, popliteal bruit and a thrill at the popliteal fossa. CT scan showed an AVF arising from the left popliteal artery. An aneurysm was seen to fill at the same time as the popliteal vein. Findings at open surgical revision included AVF between the tibioperoneal trunk and the popliteal vein and a venous popliteal aneurysm at the level of the arteriovenous communication. The aneurysm and fistula were repaired. The patient had an uneventful follow up with complete recovery. We also report an endovascular treatment of a iatrogenic arterio-venous fistula.

关键词： Arthroscopy Complication Arteriovenous Fistula Anterior Cruciate Ligament Venous Aneurysm

Universal switching of plasmonic signals using optical resonator modes

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Light(Science & Applications) 2016年第1期5卷 135-142页

作者： Cillian PT McPolin Nicolas Olivier jean-sebastien Bouillard Daniel O’Connor Alexey V Krasavin Wayne Dickson Gregory A Wurtz Anatoly V Zayats Department of Physics King’s College LondonStrandLondon WC2R 2LSUK Present address:University of Sheffield Hounsfield RoadSheffield S37RHUK Present address:University of Hull Cottingham RoadHull HU67RXUK Present address:National Physical Laboratory Hampton RoadTeddingtonMiddlesex TW110LWUK University of North Florida 1 UNF DriveJacksonvilleFL 32224USA

We propose and investigate,both experimentally and theoretically,a novel mechanism for switching and modulating plasmonic signals based on a Fano interference process,which arises from the coupling between a narrow-band optical Fabry–Pérot cavity and a surface plasmon polariton(SPP)*** SPP wave emitted from the cavity is actively modulated in the vicinity of the cavity resonances by altering the cavity Q-factor and/or resonant *** experimentally demonstrate dynamic SPP modulation both by mechanical control of the cavity length and all-optically by harnessing the ultrafast nonlinearity of the Au mirrors that form the *** electro-optical modulation scheme is also proposed and numerically *** operation of the switch via mechanical means yields a modulation in the SPP coupling efficiency of~80%,while the all-optical control provides an ultrafast modulation with an efficiency of 30%at a rate of~0.6 *** experimental observations are supported by both analytical and numerical calculations of the mechanical,all-optical and electro-optical modulation methods.

关键词： Fano resonances optical signal processing plasmonics ultrafast switching

Multi-scale high-throughput phenotyping of apple architectural and functional traits in orchard reveals genotypic variability under contrasted watering regimes

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Horticulture Research 2019年第1期6卷 1015-1029页

作者： Aude Coupel-Ledru Benoit Pallas Magalie Delalande Frederic Boudon Emma Carrie sebastien Martinez jean-Luc Regnard Evelyne Costes UMR AGAP Univ MontpellierCIRADINRAMontpellier SupAgro34398 Montpellier Cedex 5France CIRAD 34398 Montpellier Cedex 5France University of Bristol School of Biological SciencesLife Science Building24 Tyndall AvenueBristol BS81TQUK

Despite previous reports on the genotypic variation of architectural and functional traits in fruit trees,phenotyping large populations in the field remains *** this study,we used high-throughput phenotyping methods on an apple tree core-collection(1000 individuals)grown under contrasted watering ***,architectural phenotyping was achieved using T-LiDAR scans for estimating convex and alpha hull volumes and the silhouette to total leaf area ratio(STAR).Second,a semi-empirical index(IPL)was computed from chlorophyll fluorescence measurements,as a proxy for leaf ***,thermal infrared and multispectral airborne imaging was used for computing canopy temperature variations,water deficit,and vegetation *** traits estimated by these methods were compared to low-throughput in planta *** indices and alpha hull volumes were significantly correlated with tree leaf area and trunk cross sectional area,while IPL values showed strong correlations with photosynthesis measurements collected on an independent leaf *** contrast,correlations between stomatal conductance and canopy temperature estimated from airborne images were lower,emphasizing discrepancies across measurement *** heritability values were obtained for almost all the traits except leaf photosynthesis,likely due to large intra-tree *** means were used in a clustering procedure that defined six classes of architectural and functional *** between groups showed several combinations between architectural and functional traits,suggesting independent genetic *** study demonstrates the feasibility and relevance of combining multi-scale high-throughput methods and paves the way to explore the genetic bases of architectural and functional variations in woody crops in field conditions.

关键词： architectural traits functional

Design methodology of permanent magnet generators for fixed-pitch tidal turbines with overspeed power limitation strategy

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Journal of Ocean Engineering and Science 2020年第1期5卷 73-83页

作者： Sofiane Djebarri jean Frédéric Charpentier Frank Scuiller Mohamed Benbouzid ECAM Lyon LabECAMF69005 LyonFrance French Naval Academy IRENav EA 363429240 BrestFrance University of brest UMR CNRS 6027 IRDL29238 BrestFrance Shanghai Maritime University 201306 ShanghaiChina

This paper deals with a design methodology of permanent magnets(PM)generators used for fixed-pitch tidal turbines in a marine renewable energy *** the case of underwater turbines,fixed-pitch tidal turbines could be very attractive and interesting to reduce maintenance operation by avoiding using such a complex electromechanical system for *** this technological case,one of the main control challenges is to ensure power limitation at high tidal current *** control mode can be achieved using the generator *** this context,this paper proposes an original and systemic design methodology to optimize the generator design taking into account the tidal turbine power limitation for high tidal currents velocities.

关键词： Tidal turbine Fixed-pitch turbine Direct-drive PM generator Design methodology Flux-weakening power limitation.

Future for inertial-fusion energy in Europe:a roadmap

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High Power Laser Science and Engineering 2023年第6期11卷 162-192页

作者： Dimitri Batani Arnaud Colaitis Fabrizio Consoli Colin N.Danson Leonida Antonio Gizzi Javier Honrubia Thomas Kühl sebastien Le Pape jean-Luc Miquel Jose Manuel Perlado R.H.H.Scott Michael Tatarakis Vladimir Tikhonchuk Luca Volpe Centre Lasers Intenses et Applications(CELIA) Universitéde Bordeaux±CNRS±CEATalence cedexFrance ENEA Fusion and Technology for Nuclear Safety and Security DepartmentC.R.FrascatiFrascatiItaly AWE AldermastonReadingUK Centre for Inertial Fusion Studies Blackett LaboratoryImperial College LondonLondonUK Istituto Nazionale di Ottica Consiglio Nazionale delle Ricerche(CNR-INO)PisaItaly ETSIAE Universidad Politecnica de Madrid MadridSpain GSI-Helmholtzzentrum für Schwerionenforschung GmbH DarmstadtGermany Laboratoire pour l’Utilisation des Lasers Intenses(LULI) CNRS±Ecole PolytechniquePalaiseau cedexFrance ALP Le BarpFrance and CEA/DAMÎle de FranceBruyères le ChâtelArpajon cedexFrance Instituto Fusión NuclearªGuillermo Velardeº(IFN-GV) Universidad Politecnica de MadridMadridSpain Central Laser Facility STFC Rutherford Appleton LaboratoryHarwell OxfordOxfordshireUK Institute of Plasma Physics and Lasers University Research and Innovation CentreHellenic Mediterranean UniversityRethymnoCreteGreece Department of Electronic Engineering School of EngineeringHellenic Mediterranean UniversityChaniaCreteGreece Extreme Light Infrastructure ERIC ELI-Beamlines FacilityDolníBÏrežanyCzech Republic Centro de Laseres Pulsados(CLPU) Parque CientificoVillamayorSalamancaSpain

The recent achievement of fusion ignition with laser-driven technologies at the National Ignition Facility sets a historic accomplishment in fusion energy *** accomplishment paves the way for using laser inertial fusion as a viable approach for future energy *** has a unique opportunity to empower research in this field internationally,and the scientific community is eager to engage in this *** propose establishing a European programme on inertial-fusion energy with the mission to demonstrate laser-driven ignition in the direct-drive scheme and to develop pathway technologies for the commercial fusion *** proposed roadmap is based on four complementary axes:(ⅰ)the physics of laser-plasma interaction and burning plasmas;(ⅱ)high-energy high repetition rate laser technology;(ⅲ)fusion reactor technology and materials;and(ⅳ)reinforcement of the laser fusion community by international education and training *** foresee collaboration with universities,research centres and industry and establishing joint activities with the private sector involved in laser *** project aims to stimulate a broad range of high-profile industrial developments in laser,plasma and radiation technologies along with the expected high-level socio-economic impact.

关键词： education and training fusion reactor technology high-energy laser high repetition rate laser inertial confinement fusion laser-plasma interaction public-private partnership radiation resistant materials

Planning and Profit Sharing in Overlay WiFi and LTE Systems toward 5G Networks

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Journal of Software Engineering and Applications 2019年第11期12卷 491-508页

作者： Danielle Saliba Rodrigue Imad sebastien Houcke Bachar El Hassan Signal and Communication Mines Telecom Atlantique Brest France Mechatronics University of Balamand Al Kurah Lebanon Telecommunication and Networking Lebanese University Tripoli Lebanon

With the increasing demand for data traffic and with the massive foreseen deployment of the Internet of Things (IoT), higher data rates and capacity are required in mobile networks. While Heterogeneous Networks (HetNets) are under study toward 5G technology, Wireless Fidelity (WiFi) Access Points (APs) are considered a potential layer within those multiple Radio Access Technologies (RATs). For this purpose, we have proposed in this paper a novel WiFi dimensioning method, to offload data traffic from Long Term Evolution (LTE) to WiFi, by transferring the LTE energy consuming heavy users, to the WiFi network. First, we have calculated the remaining available capacity of the WiFi network based on the estimated load of each WiFi physical channel using the overlapping characteristic of the channels. Then, we were able through this dimensioning method, to calculate the minimum needed number of WiFi APs that ensure the same or better throughput for the LTE transferred users. By this method, we have ensured additional capacity in the LTE network with minimum investment cost in the WiFi network. Finally, we have estimated the profit sharing between LTE and WiFi by considering data bundles subscription revenues and the infrastructure capital and operational costs. We have calculated for each network the profit share using a coalition game theory Shapley value that pinpoints the benefit of the cooperation using the proposed dimensioning method.

关键词： LTE WiFi Offload and Coexistence 5G Heterogeneous Networks Shapley Value Profit Sharing