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Changes in smoking patterns after HIV diagnosis or antiretroviral treatment initiation: a global systematic review and meta-analysis

作者： (法)让·卢梭(jean-jacques Rousseau)

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Infectious Diseases of Poverty 2020年第2期9卷 14-22页

作者： Jobert Richie Nansseu Dalhia Noelle Tounouga jean jacques Noubiap jean Joel Bigna Department of Public Health Faculty of Medicine and Biomedical Sciences of the University of YaoundéIYaoundéCameroon Department for the Control of Disease Epidemics and PandemicsMinistry of Public HealthYaoundéCameroon Centre for Heart Rhythm Disorders University of Adelaide and Royal Adelaide HospitalAdelaideAustralia Department of Epidemiology and Public Health Centre Pasteur of CameroonPO Box 1274YaoundéCameroon School of Public Health Faculty of MedicineUniversity of Paris Sud XILe Kremlin BicêtreFrance

Background:Tobacco consumption is more life-threatening in people living with human immunodeficiency virus(HIV)than within the general population;therefore,people living with HIV(PLWH)should be highly motivated to take action towards quitting smoking at or after HIV *** aim of this systematic review with meta-analysis was to investigate changes in smoking habits among PLWH over *** text:We considered prospective and retrospective cohort studies including PLWH aged 15 years and above,which have measured the prevalence of tobacco smoking(current,former or never)at study initiation and completion,and published between January 1,2000 and April 15,2018 without language or geographical *** searched PubMed,EMBASE,Web of Science,Africa Journal Online,and Global Index *** used a random-effects model to pool *** studies were *** proportion of current and former smokers decreased slightly over time,around 2.5 and 3.8%,***,the proportion of never smokers decreased sharply by 22.5%,and there were 2.1 and 1.5%PLWH who shifted from never and former smoking to current smoking,*** the other hand,10.5%PLWH shifted from current to former smoking,7.1%tried to quit tobacco consumption but failed,and 10.1%stayed in the"never smoking"category over ***:PLWH seem not to change positively their smoking habits towards quitting tobacco *** is urgent need to increase actions aimed at helping this vulnerable population to quit tobacco consumption,including individually tailored therapeutic education,psychosocial and pharmacologic supports.

关键词： Smoking HIV AIDS Tobacco Global health

End-of-Pregnancy Monitoring at CHUMEFJE through the Functional Investigation Centre (FIC) in 2022

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Exercise-induced albuminuria vs circadian variations in blood pressure in type 1 diabetes

Open Journal of Obstetrics and Gynecology（妇产科期刊） 2024年第1期

作者： Ulysse Pascal Minkobame Zaga Minko Opheelia Makoyo Komba Pamphile Assoumou Obiang Anouchka Mewie Lendzinga Elsy Ntsame Mezui Irenee Edzo Mvono jacques Albert Bang Ntamack jean François Meye

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World Journal of Diabetes 2017年第2期8卷 74-79页

作者： Isabelle Hota Tadida Meli Aurel T Tankeu Mesmin Y Dehayem David Chelo jean jacques N Noubiap Eugene Sobngwi Institut Supérieur des Sciences de la Santé Université des Montagnes Department of Internal Medicine and Specialties Faculty of Medicine and Biomedical Sciences National Obesity Center Yaoundé Central Hospital Mother and Child Center of the Chantal Biya Foundation Department of Medicine Groote Schuur Hospital and University of Cape Town

AIM To investigated the relationship between exerciseinduced ambulatory blood pressure measurement(ABPM) abnormalities in type 1 diabetes mellitus(T1DM) adolescents. METHODS We conducted a case-control at the National Obesity Center of the Yaoundé Central Hospital, Cameroon. We compared 24 h ABPM and urinary albumin-to-creatinine ratio(ACR) at rest and after a standardized treadmill exercise between 20 Cameroonian T1 DM patients and 20 matched controls. T1 DM adolescents were aged 12-18 years, with diabetes for at least one year, without proteinuria, with normal office blood pressure(BP) and renal function according to the general referencepopulation. Non-diabetic controls were adolescents of general population matched for sex, age and *** Mean duration of diabetes was 4.2 ± 2.8 years. The mean 24 h systolic blood pressure(SBP) and diastolic blood pressure(DBP) were respectively 116 ± 9 mm Hg in the diabetic group vs 111 ± 8 mm Hg in the nondiabetic(P = 0.06), and 69 ± 7 mm Hg vs 66 ± 5 mm Hg(P = 0.19). There was no difference in the diurnal pattern of BP in diabetes patients and non-diabetic controls(SBP: 118 ± 10 mm Hg vs 114 ± 10 mm Hg, P = 0.11; DBP: 71 ± 7 mm Hg vs 68 ± 6 mm Hg, P = 0.22). Nighttime BP was higher in the diabetic group with respect to SBP(112 ± 11 mm Hg vs 106 ± 7 mm Hg, P = 0.06) and to the mean arterial pressure(MAP)(89 ± 9 mm Hg vs 81 ± 6 mm Hg, P = 0.06). ACR at rest was similar in both groups(5.5 mg/g vs 5.5 mg/g, P = 0.74), but significantly higher in diabetes patients after exercise(10.5 mg/g vs 5.5 mg/g, P = 0.03). SBP was higher in patients having exercise-induced albuminuria(116 ± 10 mm Hg vs 108 ± 10 mm Hg, P = 0.09). CONCLUSION Exercise-induced albuminuria could be useful for early diagnosis of kidney damage in adolescents with T1 DM.

关键词： Albuminuria Blood pressure Ambulatory blood pressure measurement Exercise Type 1 diabetes

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A new hemostatic agent composed of Zn^(2+)-enriched Ca^(2+)alginate activates vascular endothelial cells in vitro and promotes tissue repair in vivo

作者： (法)让-雅克·卢梭(jean-jacques Rousseau)

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Bioactive Materials 2022年第12期7卷 368-382页

作者： Anne-Charlotte Ponsen Richard Proust Sabrina Soave Françoise Mercier-Nom´e Isabelle Garcin Laurent Combettes jean-jacques Lataillade Georges Uzan INSERM UMRS-MD 1197 Universit´e Paris-SaclayInstitut Andr´e LwoffHˆopital Paul BrousseVillejuifFrance Plateforme d’Histologie Immunopathologie de Clamart(PHIC) Universit´e Paris-SaclayINSERMCNRSInstitut Paris Saclay d’Innovation Th´erapeutiqueChˆatenay-MalabryFrance Universit´e Paris-Saclay INSERMInflammationMicrobiome and ImmunosurveillanceClamartFrance INSERM UMRS 1174 Universit´e Paris-SaclayOrsayFrance Centre de Transfusion Sanguine des Arm´ees ClamartFrance

To control capillary bleeding, surgeons may use absorbable hemostatic agents, such as Surgicel® and TachoSil®. Due to their slow resorption, their persistence in situ can have a negative impact on tissue repair in the resected organ. To avoid complications and obtain a hemostatic agent that promotes tissue repair, a zinc-supplemented calcium alginate compress was developed: HEMO-IONIC®. This compress is non-absorbable and is therefore removed once hemostasis has been achieved. After demonstrating the hemostatic efficacy and stability of the blood clot obtained with HEMO-IONIC, the impact of Surgicel, TachoSil, and HEMO-IONIC on cell activation and tissue repair were compared (i) in vitro on endothelial cells, which are essential to tissue repair, and (ii) in vivo in a mouse skin excision model. In vitro, only HEMO-IONIC maintained the phenotypic and functional properties of endothelial cells and induced their migration. In comparison, Surgicel was found to be highly cytotoxic, and TachoSil inhibited endothelial cell migration. In vivo, only HEMO-IONIC increased angiogenesis, the recruitment of cells essential to tissue repair (macrophages, fibroblasts, and epithelial cells), and accelerated maturation of the extracellular matrix. These results demonstrate that a zinc-supplemented calcium alginate, HEMO-IONIC, applied for 10 min at the end of surgery and then removed has a long-term positive effect on all phases of tissue repair.

关键词： Hemostatic agent Alginate Surgery Hemostasis Endothelial cells Tissue repair

The Importance of Spatiotemporal Heterogeneity for Biodiversity in Forest—Heathland Mosaics and Implications for Heathland Conservation

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Journal of Environmental Protection 2016年第10期7卷 1317-1332页

作者： Samira Mobaied jean-jacques Geoffroy Nathalie Machon Centre d’Ecologie et des Sciences de la Conservation (CESCO UMR7204) Sorbonne University MNHN CNRS UPMC CP51 Paris France Museum National d’Histoire Naturelle CNRS UMR MNHN UPMC 7204 Conservation of Species Restoration and Monitoring of Populations Brunoy France

In biodiversity management, spatio-temporal heterogeneity is important to consider conserving high levels of habitat diversity and ecosystems. In this study, we investigated the relationship between landscape spatio-temporal heterogeneity and biodiversity in a mosaic-landscape, located in the Fontainebleau forest (France). The diversity of successional stages along a gradient from heathland to forest as well as the persistence of Calluna vulgaris (L.) Hull in different forest stands was examined in order to find how the numerous patches of European Heathland habitat embedded in this area should be maintained. The results indicated that in the areas of high spatio-temporal heterogeneity, a general increase is observed in species richness, in particular for vascular plants, bryophytes and carabids. C. vulgaris persisted in coniferous stands and young mixed stand but decreased under deciduous trees and old mixed stands. The Ellenberg’s values for light, nutrients and acidity, show the persistence of favorable enviromental conditions for heathland vegetation under coniferous stands and young mixed stands. These results enable us to offer recommendations to better manage mosaic-landscape biodiversity, and in particular, the heathland semi-natural habitats in the Fontainebleau forest and elsewhere in Europe.

关键词： Spatiotemporal Heterogeneity Conservation Management Calluna vulgaris Biodiversity

Front-of-pack labeling:a health literacy intervention to improve cardiovascular health in Sub-Saharan Africa

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Global Health Journal 2022年第4期6卷 227-230页

作者： Boni Maxime Ale jean jacques Noubiap Holo Healthcare Limited NairobiKenya Centre for Heart Rhythm Disorders the University of AdelaideAdelaideAustralia

There is a surge in the burden of cardiovascular disease(CVD)in Sub-Saharan African(SSA)*** the last 50 years there has been a rapid growth in the consumption of ultra-processed food products high in salt,fat,and glycemic load in *** is overwhelming evidence linking UPFP consumption to an increased risk of coronary artery disease,cerebrovascular disease,overall CVD,and all-cause ***-of-pack labeling(FOPL)represents an important intervention to guide consumers towards healthier diets and ultimately contribute to the prevention of diet-related adverse health outcomes including *** paper discusses the challenges in the development and implementation of FOPL systems in SSA,and proposes some key elements that would be critical for developing an effective FOPL system in SSA countries.

关键词： Front-of-pack labeling Diet Cardiovascular Sub-Saharan Africa

On the MOSFET-Based Temperature Sensitive Element for Bolometer Application

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Journal of Earth Science and Engineering 2014年第8期4卷 464-469页

作者： Etienne Fuxa jean-jacques Yon Jalal Jomaah Bolometer Research Group (LIB) DOPT (Department of Optics & Photonics) CEA (Alternative Energies and Atomic EnergyCommission) LETI Grenoble 38000 France LAHC (Laboratory of Hyperfrequencies and Characterization) IMEP (Mieroelectronics Electromagnetism and PhotonicsInstitute) Grenoble 38000 France

This paper focuses on the study of thermal performances of MOS （metal-oxide-semiconductor） transistors for uncooled infrared bolometer applications. Such devices can be used in various applications both military and civil, such as defence and security, medical applications, industrial surveillance, etc. Series of measurements were conducted to obtain TCC （temperature coefficient of current） versus gate voltage and temperature curves. The TCC is a figure of merit for a device used as the sensitive element in a bolometer that represents its sensitivity to temperature and as such is a good indicator of the detector attainable performance. The measurements were confronted to Atlas simulations, and showed that in the subthreshold region the TCC ranges from 4%/K all the way to 9%/K which represents a great improvement compared to state of the art thermistor bolometers. Analytic expressions of the TCC are also derived from current equations of the MOSFET （MOS field effect transistor） drain current to help understanding the effect of drain to source voltage, mobility, temperature and threshold voltage sensibility to temperature, in all three operation modes of the transistor （subthreshold, ohmic and saturation）. It was also determined that gate length does not have an influence on the TCC until short channel effects are factored in.

关键词： Bolometer uncooled infrared detection MOSFET.