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World Journal of Gastroenterology 2007年第15期13卷 2255-2257页

作者： David Bertolini Philippe De Saussure Michael Chilcott marc Girardin jean-marc dumonceau Divisions of Gastroenterology and Hepatology Geneva University Hospitals GenevaSwitzerland Department of Digestive Surgery Geneva University Hospitals GenevaSwitzerland

Percutaneous endoscopic colostomy （PEC） is increasingly proposed as an alternative to surgery to treat various disorders, including acute colonic pseudo-obstruction, chronic intestinal pseudo-obstruction and relapsing sigmoid volvulus. We report on a severe complication that occurred two months after PEC placement. A 74-year-old man with a history of chronic intestinal pseudo-obstruction evolving since 8 years was readmitted to our hospital and received PEC to provide long-standing relief. The procedure was uneventful and greatly improved the patient＇s quality of life. Two months later, the patient developed acute stercoral peritonitis. At laparotomy, the colostomy flange was embedded in the abdominal wall but no pressure necrosis was found at the level of the colonic wall. This complication was likely related to inadvertent traction of the colostomy tube. Subtotal colectomy with terminal ileostomy was performed. We review the major features of 60 cases of PEC reported to date, including indications and complications.

关键词： Percutaneous endoscopic colostomy Complications Colonic pseudo-obstruction Ileus Peritonitis

Carbon dioxide for gut distension during digestive endoscopy:Technique and practice survey

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World Journal of Gastroenterology 2009年第12期15卷 1475-1479页

作者： Filip Janssens Jacques Deviere Pierre Eisendrath jean-marc dumonceau Division of Gastroenterology and Hepatology Geneva University HospitalsMicheli-du-Crest street241205 GenevaSwitzerland Medical-Surgical Department of Gastroenterology and Hepato-Pancreatology Erasme HospitalUniversité Libre de BruxellesBrusselsBelgium

AIM:To assess the adoption of Carbon dioxide(CO2)insufflation by endoscopists from various European countries,and its ***:A survey was distributed to 580 endoscopists attending a live course on digestive ***:The response rate was 24.5%.Fewer than half the respondents(66/142,46.5%)were aware of the fact that room air can be replaced by CO2 for gut distension during endoscopy,and 4.2%of respondents were actually using CO2 as the insufflation *** aware of the possibility of CO2 insufflation mentioned technical difficulties in implementing the system and the absence of significant advantages of CO2 in comparison with room air as barriers to adoption in daily practice(84%and 49%of answers,respectively;two answers were permitted for this item).CONCLUSION:Based on this survey,adoption of CO2 insufflation during endoscopy seems to remain relatively exceptional.A majority of endoscopists were not aware of this possibility,while others were not aware of recent technical developments that facilitate CO2 implementation in an endoscopy suite.

关键词： Colonoscopy Practice survey Carbondioxide Digestive endoscopy

Endoscopic ultrasonography-guided fine needle aspiration:Relatively low sensitivity in the endosonographer population

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World Journal of Gastroenterology 2012年第19期18卷 2357-2363页

作者： jean-marc dumonceau Thibaud Koessler jeanin E van Hooft Paul Fockens Division of Gastroenterology and Hepatology Geneva University Hospital1211 GenevaSwitzerland Division of General Internal Medicine Geneva University Hospital1211 GenevaSwitzerland Gastrointestinal Endoscopy Academic Medical Center University of Amsterdam1012 WXAmsterdamThe Netherlands

AIM： To assess the characteristics and quality of endoscopic ultrasonography-guided fine needle aspiration （EUS-FNA） in a large panel of endosonographers.METHODS： A survey was conducted during the 13th annual live course of endoscopic ultrasonography （EUS） held in Amsterdam, Netherlands. A 2-page question- naire was developed for the study. Content validity of the questionnaire was determined based on input by experts in the field and a review of the relevant literature. It contained 30 questions that pertained to demographics and the current practice for EUS-FNA of responders, including sampling technique, sample processing, cytopathological diagnosis and sensitivity of EUS-FNA for the diagnosis of solid mass lesions. One hundred and sixty-one endosonographers whoattended the course were asked to answer the survey. This allowed assessing the current practice of EUS-FNA as well as the self-reported sensitivity of EUS-FNA for the diagnosis of solid mass lesions. We also examined which factors were associated with a self-reported sensitivity of EUS-FNA for the diagnosis of solid mass lesions 〉 80%.RESULTS： Completed surveys were collected from 92 （57.1%） of 161 endosonographers who attended the conference. The endosonographers had been practio ing endoscopy and EUS for 22.5 4. 7.8 years and 4.8 4- 4.1 years, respectively; one third of them worked in a hospital with an annual caseload 〉 100 EUS-FNA. Endoscopy practices were located in 29 countries, in- cluding 13 countries in Western Europe that totaled 75.3% of the responses. Only one third of endosonog raphers reported a sensitivity for the diagnosis of solid mass lesions 〉 80% （interquartile range of sensitivities, 25.0%-75.0%）. Factors independently associated with a sensitivity 〉 80% were （1）〉 7 needle passes for pancreatic lesions or rapid on-site cytopathological evaluation （ROSE）（P 〈 0.0001）, （2） a high annual hospital caseload （P = 0.024） and （3） routine isolation of microcores from EUS-FNA samples （P =

关键词： Caseload Community surveys Cytopa- thology Endoscopic ultrasonography Histopathology Quality improvement

Concomitant autoimmune and genetic pancreatitis leads to severe inflammatory conditions

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World Journal of Gastroenterology 2008年第16期14卷 2596-2598页

作者： jean Louis Frossard jean marc dumonceau Catherine Pastor Laurent Spahr Antoine Hadengue Division de Gastroentérologie et Hépatologie Geneva University Hospital

Chronic pancreatitis characterized by an early onset should be extensively investigated including the search for a mutation of the PRSS1, SPINK-1 or CFTR genes and potential features of autoimmune pancreatitis. We here describe a case of chronic pancreatitis with an onset at a very young age in which a mutation of the PRSS1 and several features of autoimmune pancreatitis were identified.

关键词： Chronic pancreatitis Genetics Autoimmunepancreatltis SPINK-1 CFTR PRSS1

Endoscopic management of complications of chronic pancreatitis

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World Journal of Gastroenterology 2013年第42期19卷 7308-7315页

作者： jean-marc dumonceau Carlos Macias-Gomez Division of Gastroenterology and Hepatology Geneva University Hospital1211 GenevaSwitzerland Gastrointestinal Endoscopy Unit Gastroenterology ServiceItalian Hospital1181 Buenos AiresArgentina

Pseudocysts and biliary obstructions will affect approximately one third of patients with chronic pancreatitis(CP).For CP-related,uncomplicated,pancreatic pseudocysts(PPC),endoscopy is the first-choice therapeutic *** advances have focused on endosonography-guided PPC transmural drainage,which tends to replace the conventional,duodenoscope-based coma immediately *** material is being tested to facilitate the endosonography-guided *** this review,the most adequate techniques depending on PPC characteristics are presented along with supporting *** CP-related biliary obstructions,endoscopy and surgery are valid therapeutic *** co-morbidities(e.g.,portal cavernoma)and expected patient compliance to repeat endoscopic procedures are important factors when selecting the most adapted *** should be reasonably ruled out before embarking on the endoscopic treatment of presumed CP-related biliary *** endoscopy,the gold standard technique consists of placing simultaneous,multiple,side-by-side,plastic stents for a oneyear *** covered self-expandable metal stents are challenging this method and have provided 50%mid-term success.

关键词： Biliary stricture Chronic pancreatitis Pseudocyst Endoscopic retrograde cholangio-pancreatography Endoscopic ultrasonography Stent

Bound and Resonating Multiquark Configurations

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Chinese Physics Letters 2024年第8期41卷 8-12页

作者： jean-marc Richard Institut de Physique des 2 Infinis de Lyon Université Claude Bernard(Lyon 1) CNRS-IN2P34 rue Enrico Fermi69622 VilleurbanneFrance

We review the predictions of quark models for multiquark configurations that are bound or resonant states,and compare different methods for estimating the properties of resonances.

关键词： quark Configuration resonant

Populism as a Crisis of Democratic Legitimacy:With Some References to France and the United States

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Fudan Journal of the Humanities and Social Sciences 2024年第2期17卷 193-209页

作者： jean-marc Coicaud Law and Global Affairs Rutgers UniversityRutgersUSA Fudan Institute for Advanced Study in Social Sciences ShanghaiChina

Populism combines the following characteristics:a rejection of economic policies linked to globalization;a condemnation of political and economic elites perceived as allied,directly or indirectly,to globalization policies;a nationalist conception of the national interest;a mistrust of immigration,seen as a threat to identity;as for populism’s supporters,a rather popular sociological profile,and an electoral profile that tends toward the“hard right”(“droite dure”),without ruling out bridges to the“hard left”(“gauche dure”).Having said this,I propose to defend three theses:populism is not the solution to the problems of the countries where it is developing,whether in France,the United States or elsewhere;it would be dangerous,however,to ignore the crises of which populism is the product;it is essential to take the measure of the problems that favor its emergence and to try to provide answers to them.

关键词： Populism Democratic legitimacy Hard right Hard left

Endoscopic management of biliary complications after liver transplantation: An evidence-based review

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World Journal of Gastrointestinal Endoscopy 2015年第6期7卷 606-616页

作者： Carlos Macías-Gómez jean-marc dumonceau Gastroenterology Service Hospital Italiano de Buenos Aires Division of Gastroenterology and Hepatology Geneva University Hospitals

Biliary tract diseases are the most common complications following liver transplantation(LT) and usually include biliary leaks, strictures, and stone disease. Compared to deceased donor liver transplantation in adults, living donor liver transplantation is plagued by a higher rate of biliary complications. These may be promoted by multiple risk factors related to recipient, graft, operative factors and post-operative course. Magnetic resonance cholangiopancreatography is the first-choice examination when a biliary complication is suspected following LT, in order to diagnose and to plan the optimal therapy; its limitations include a low sensitivity for the detection of biliary sludge. For treating anastomotic strictures, balloon dilatation complemented with the temporary placement of multiple simultaneous plastic stents has become the standard of care and results in stricture resolution with no relapse in > 90% of cases. Temporary placement of fully covered self-expanding metal stents(FCSEMSs) has not been demonstrated to be superior(except in a pilot randomized controlled trial that used a special design of FCSEMSs), mostly because of the high migration rate of current FCSEMSs models. The endoscopic approach of non-anastomotic strictures is technically more difficult than that of anastomotic strictures due to the intrahepatic and/or hilar location of strictures, and the results are less satisfactory. For treating biliary leaks, biliary sphincterotomy and transpapillary stenting is the standard approach and results in leak resolution in more than 85% of patients. Deep enteroscopy is a rapidly evolving technique that has allowed successful treatment of patients who were not previously amenable to endoscopic therapy. As a result, the percutaneous and surgical approaches are currently required in a minority of patients.

关键词： Biliary stricture Bile leakage Liver transplantation Endoscopic retrograde cholangio-pancreatography Plastic stents Fully-covered self-expandablemetal stents

Pd_(20)Pt_(20)Cu_(20)Ni_(20)P_(20)高熵金属玻璃的热稳定性和热塑成形性

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稀有金属材料与工程 2024年第1期53卷 1-7页

作者： Cardinal Sandrine Pelletier jean-marc Kato Hidemi 里昂大学里昂国立应用科学学院法国里昂F-69621 东北大学金属材料研究所日本仙台980-8577

采用差示扫描量热法、X射线衍射和热力学分析研究了Pd_(20)Pt_(20)Cu_(20)Ni_(20)P_(20)高熵金属玻璃(HEMG)的热稳定性和热力学性能。结果表明,与其他经典贵金属基金属玻璃相比,Pd_(20)Pt_(20)Cu_(20)Ni_(20)P_(20)HEMG具有相当的性能... 详细信息

采用差示扫描量热法、X射线衍射和热力学分析研究了Pd_(20)Pt_(20)Cu_(20)Ni_(20)P_(20)高熵金属玻璃(HEMG)的热稳定性和热力学性能。结果表明,与其他经典贵金属基金属玻璃相比,Pd_(20)Pt_(20)Cu_(20)Ni_(20)P_(20)HEMG具有相当的性能和鲜明的特点。

关键词：高熵合金金属玻璃热塑性成形结晶

Hf元素添加对CuZr基非晶合金动态弛豫的影响

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力学学报 2024年第8期56卷 2282-2293页

作者：朱凡邢光辉 jean-marc Pelletier 乔吉超西北工业大学力学与土木建筑学院西安710072 东莞市三航军民融合创新研究院广东东莞523808 INSA-Lyon MATEIS UMR5510F-69621 VilleurbanneFrance

考虑到非晶合金具有独特的无序微观结构,其表现出极为复杂的弛豫动力学特性.动态弛豫行为在非晶合金中普遍存在,深刻理解其机制对于解构非晶合金固有的非均匀微观结构至关重要.少量元素的添加是调控非晶合金微观结构有效手段之一.本研... 详细信息

考虑到非晶合金具有独特的无序微观结构,其表现出极为复杂的弛豫动力学特性.动态弛豫行为在非晶合金中普遍存在,深刻理解其机制对于解构非晶合金固有的非均匀微观结构至关重要.少量元素的添加是调控非晶合金微观结构有效手段之一.本研究以玻璃形成能力良好的Cu_(46)Zr_(47-x)Hf_(x)Al_(7)(x=0,8)非晶合金为模型合金,运用动态力学分析方法研究复模量随频率和温度的变化,进而探究Hf元素取代Zr元素对动态弛豫的影响.在动态力学频率谱中,借助准点缺陷理论阐明非晶合金在玻璃转变温度T_(g)以下处于等构型状态,准点缺陷浓度保持恒定;而在T_(g)以上,准点缺陷浓度随温度的上升呈线性增加.Hf元素的添加会降低玻璃体系等构型状态下的准点缺陷浓度,并抑制原子迁移能力.通过获取连续和离散的弛豫时间分布,直观展示了非晶合金的动力学非均匀性特征.在动态力学温度谱中,Hf元素的引入增加了玻璃体系的混合焓,抑制了β弛豫强度.进一步从内耗角度表明,Hf元素的引入不仅提高了与β弛豫相关的基本结构单元的激活难度,还增加了整个β弛豫过程的激活能.

关键词：非晶合金动态弛豫微合金化准点缺陷微观结构非均匀性