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Epidemic Diseases and Chinese Medicine: Example of SARS and COVID-19: Part Two

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Chinese Medicine and Culture 2019年第3期2卷 121-132页

作者： jean-claude Dubois Georges Pompidou European Hospital Anti-Pain Center Faculty of MedicineParis V Rene Descartes UniversityParisFrance

Along with the legends about epidemic demons,China has developed over the centuries a medical approach to epidemic diseases based on the teachings of Hucng Di Nei Jing(《黄帝内经》Huangdi s Intermnal Classic),Nan Jing(《难经》Classic of Difficult Issues),and Shang Han Lun(《伤寒论》Treatise on Cold Damage).Other doctors and scientists participated in this evolution of knowledge,like Wang Shuhe(王叔和),Ge Hong(葛洪),Chao Yuanfang(巢元方),Sun Simiao(孙思邈),and Liu Wansu(刘完素).However,it was in the 17^th century,after the great break of the Song,Jin,and Yuan eras that an innovative spirit,Wu Youke(吴又可1582-1652)first foresaw the existence of microorganisms as we know them *** Wen Yi Lun(《瘟疫论》Treatise on Pestilence)foreshadows an original approach to epidemic diseases,particularly emerging infectious diseases of the 21^st *** them,traditional Chinese medicine developed a comprehensive method of diagnosing and treating of these diseases(Epidemic Diseases Theory瘟疫学说)within the School ofHeat Diseases(温病学派).In a third article,we will examine some applications in the treatment of the SARS 2003-2004 epidemic(非典型肺炎)and the current COVID-19(新型冠状病毒肺炎)pandemic.

关键词： Chinese medical history epidemic diseases theory SARS COVID-19 Sun Zi Bing Fa(《孙子兵法》Art of War) Wen hiLun(《瘟疫论》Treatise on Pestilence) Wu Youke(吴又可)

Lanthanide mechanoluminescence

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Journal of Rare Earths 2018年第1期36卷 1-41页

作者： jean-claude G.Bünzli Ka-Leung Wong Institute of Chemical Sciences and Engineering Swiss Federal Institute of Technology Lausanne (EPFL) CH-1015 Lausanne Switzerland Department of Chemistry Hong Kong Baptist University Kowloon Tong Hong Kong China

Mechanoluminescence （ML） is the emission of light consecutive to a mechanical force or stress imposed to a crystalline material. Many inorganic and organic compounds present this phenomenon that is known for over 400 years. Lanthanide and uranyl salts were among the first substances investigated for this property. Mechanoluminescence, also referred to as triboluminescence, is often considered as being a badly understood phenomenon. In fact it is because of two main reasons. Firstly, a variety of different mechanical stresses, from simple rubbing, to applied pressure, crushing, impact of a weight, ultrasound, laser-generated shock wave, crystallization, dissolution of crystals, or even wind can trigger it. Secondly, ML is very sensitive to the purity and morphology of the sample： in inorganic compounds, generation of traps by doping ＂impurities＂（e.g. lanthanide ions） is responsible for light emission so that the exact composition of the sample has to be known to a very detailed level; for chelates, the crystallization conditions are crucial since they often generate extended networks of weak interactions that are instrumental in triggering ML when they are broken. In fact mechanisms of ML are relatively well known and theories and models often reproduce very well the experiments. Additionally, practical applications are at hand, for example stress, crack, and impact sensors based on SrAI204：Eu11 or Et3NH[Eu（dbm）4] are used to test structures and materials as diverse as road bridges, reinforced concrete elements, pressur- ized containers or airplane wings and to image the propagation of cracks or stress distribution. Military and security applications involve detecting the passage of vehicle or soldiers and producing counter- feiting inks while more joyful applications are luminous balls, wrapping papers and adhesive tapes. Not only bulk materials, but micro- and nanoparticles feature mechanoluminescent properties and single particle manipulation under an AFM allows

关键词： MechanoluminescenceRare earthsStress sensorsPressure sensorsImpact sensors

Epidemic Diseases and Chinese Medicine:Example of Severe Acute Respiratory Syndrome and COVID-19

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Chinese Medicine and Culture 2020年第2期3卷 60-64页

作者： jean-claude Dubois Georges Pompidou European Hospital Anti-Pain Center Faculty of MedicineParis V Rene Descartes UniversityParisFrance

Epidemic diseases,known and studied in China since antiquity,are one of the main chapters of the School of Exogenous Febrile Diseases(温病学派)•Along with the legends about epidemic demons,China has developed over the centuries a medical approach based on the teachings of Huang Di Nei Jing(《黄帝内经》Internal Classic),Nan Jing(《难经》Classic of Difficulties'),and Shang Han Lun(《伤寒论》Treatise of Harmful Cold).However,it was in the 17th century,after the great break of the Song,Jin,and Yuan eras that an innovative spirit Wu Youxing(吴有性)first foresaw the existence of microorganisms as we know them *** Wen Yi Lun(《瘟疫论》Treatise on Pestilences)foreshadows an original approach to epidemic diseases,particularly emerging infectious diseases of the 21st century:severe acute respiratory syndrome 2003-2004 and the COVID-19 pandemic are perfect *** this first article,which will be followed by two others,we will examine the classical and modern Chinese definitions of these dreadful plagues.

关键词： Ancient and modern terminology epidemic geniuses and demons pestilences severe acute respiratory syndrome and COVID-19 traditional medical approach

Lanthanide NIR luminescence for telecommunications, bioanalyses and solar energy conversion

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Journal of Rare Earths 2010年第6期28卷 824-842页

作者： jean-claude G. Bünzli Svetlana V. Eliseeva cole Polytechnique Fédérale de Lausanne Institute of Chemical Sciences and Engineering WCU Professor Korea University Center for Next Generation Photovoltaic Systems Katholieke Universiteit Leuven Department of Chemistry Laboratory of Coordination Chemistry

Present-day advanced technologies heavily rely on the exciting magnetic and spectroscopic properties of lanthanide ions. In particular, their ability to generate well-characterized and intense near-infrared (NIR) luminescence is exploited in any modern fiber-optic telecommunication network. In this feature article, we first summarize the whereabouts underlying the design of highly luminescent NIR molecular edifices and materials. We then focus on describing the main trends in three applications related to this spectral range: telecommunications, biosciences, and solar energy conversion. In telecommunications, efforts concentrate presently on getting easily processable polymer-based waveguide amplifiers. Upconversion nanophosphors emitting in the visible after NIR excitation are now ubiquitous in many bioanalyses while their application to bio-imaging is still in its early stages; however, highly sensitive NIR-NIR systems start to be at hand for both in vitro and in vivo imaging, as well as dual probes combining magnetic resonance and optical imaging. Finally, both silicon-based and dye-sensitized solar cells benefit from the downconversion and upconversion capabilities of lanthanide ions to harvest UV and NIR solar light and to boost the overall quantum efficiency of these next-generation devices.

关键词： lanthanide luminescence near-infrared luminescence telecommunications bioanalysis solar energy conversion solar cell upconversion downconversion

Revisiting the Medical Work of George Soulie De Morant

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Chinese Medicine and Culture 2019年第2期2卷 53-56页

作者： jean claude Dubois Anti-Pain Center Georges Pompidou European Hospital(HEGP)ParisFrance

It is now time to revisit the medical work of George Soulie de Morant(1878-1955).Over the past 64 years,studies and research on acupuncture-moxibustion have undergone exceptional growth in China,and Western sinology h... 详细信息

关键词： Acupuncture Chinese medicine france needles and moxas sinology Soulie de Morant

Early Prosthetic Valve Endocarditis with Mycobacterium Tuberculosis after Mitral Valve Replacement: A Case Report

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World Journal of Cardiovascular Surgery 2024年第3期14卷 33-40页

作者： Papa Amath Diagne Mory Camara Papa Ousmane Ba Momar Sokhna Diop Moussa Samba Abdou Lahad Mbengue jean claude Ndiogou Dione Myriam Bizrane Marième Soda Mbaye Moussa Seck Diop Toudiani Malam Kaka Papa Salmane Ba Papa Adama Dieng Amadou Gabriel Ciss Assane Ndiaye Cardiovascular and Thoracic Surgery Department FANN National University Hospital Dakar Senegal

Background: Tuberculous endocarditis is a rare but serious complication of heart valve replacement surgery. We report the case of a 24-year-old patient, who presented with tuberculous endocarditis after mechanical mitral valve replacement, with a favorable clinical course following anti-tuberculosis treatment. Case Presentation: We report a 24-year-old male patient, admitted to the cardiac surgery department of the Fann Hospital (Dakar, Senegal), for the management of severe mixed (rheumatic and endocarditic) mitral insufficiency with associated tricuspid insufficiency. He had a history of recurrent angina and polyarthralgia in childhood, was hospitalized several times for refractory global cardiac decompensation, and for a suspected infective endocarditis a month before his admission. On admission, the clinical examination revealed signs suggestive of mitral and tricuspid insufficiency. Transthoracic echocardiography revealed severe post-endocarditic mitral insufficiency with A3 amputation, highly mobile 15 mm vegetations on the free edge of the large valve, moderate tricuspid insufficiency, and severe pulmonary artery hypertension. Mechanical mitral valve replacement and tricuspid valve annuloplasty using autologous pericardial strip were performed via median sternotomy. After ten days, the patient presented with global cardiac decompensation associated with a clinico-biological infectious syndrome, and tans-oesophageal echography revealed an abscess at the sinotubular junction, communicating with the aorta. A thoraco-abdomino-pelvic CT scan was done, which revealed a bilateral alveolar-interstitial syndrome with mediastinal lymphadenopathy. Anti-tuberculosis treatment with RHZE was initiated for 06 months. The clinical course was favorable. Conclusion: Tuberculous endocarditis in prostheses is a serious complication of heart valve replacement surgery, which may evolve favorably under medical treatment.

关键词： Tuberculous Endocarditis Prosthetic Valve Endocarditis Mycobacterium Tuberculosis

Factors Associated with HIV/Tuberculosis Coinfection among People Living with HIV after Initiation of Antiretroviral Treatment in Lingwala Health Zone from 2021 to 2023

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Population genetic structure of the biological control agent Macrolophus pygmaeus in Mediterranean agroecosystems

Advances in Infectious Diseases（传染病进展） 2024年第1期 176页

作者： jean claude Mikobi Maleshila Espérant Ntambue Malu Fabrice Sewolo Tacite Kpanya Mazoba jean Nyandwe Kyloka

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Insect Science 2017年第5期24卷 859-876页

作者： jean-claude Streito Cecile Clouett Faten Hamdi Nathalie Gauthier IRD UMR (INRA/IRDICiradlMontpellier SupAgro) Centre de Biologie pour la Gestion des Populations INRA UMR (INRA/IRDI CiradlMontpellier SupAgro) Centre de Biologie pour la Gestion des Populations 755 avenue du Campus Agropolis CS 30016 34988Montferrier-sur-Lez France

Biological control of agricultural pests relies on knowledge of agroecosystem functionality, particularly when affected by the use of mass-produced biological agents. Incorporating pre- and/or post-release information such as genetic diversity and struc- ture on these agents using molecular-based approaches could advance our knowledge of how they perform in agroecosystems. We evaluated the population genetics of Macrolo- phus pygmaeus, the most widely used predatory mirid against many arthropod pests of greenhouse crops in the Mediterranean region, using the mitochondrial Cytb sequence and microsatellite data, and population genetics and phylogeny approaches. We investigated commercially mass-produced insects （i.e., commercial insects either mass-reared in the laboratory for many generations, or purchased by farmers and released in the greenhouses） and ＂wild＂ insects （i.e., that occur naturally outside or are collected in nature for release in the greenhouses）. The mirids were mainly collected in agroecosystems in which solana- ceous plants are grown in northern Spain, southern France and Greece. Both molecular markers and approaches distinguished 2 genetically differentiated populations. The less genetically diverse population, hereafter named the ＂commercial＂ strain included all indi- viduals from laboratory mass-rearings and most releases of commercially bred individuals. The most genetically diverse population mainly comprised individuals originating from noncultivated environments, or from releases of＂wild＂ individuals. Rare examples of hy- bridization between M. pygmaeus from the 2 populations were observed and asymmetric gene flow was revealed. These findings provide new insights into what happens to M. pyg- maeus released in the agroecosystems we studied, and show that it is possible to monitor some commercial strains.

关键词： biological control commercial vs. wild strains Macrolophus pygmaeus microsatellites mtCytb population genetics

Fast Multi-Operator Image Resizing and Evaluation

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Journal of Computer Science & Technology 2012年第1期27卷 121-134页

作者： Wei-Ming Dong Guan-Bo Bao Xiao-Peng Zhang jean-claude Paul Sino-French Laboratory for Computer Science Automation and Applied Mathematics/National Laboratory of Pattern RecognitionInstitute of AutomationChinese Academy of SciencesBeijing 100190China National Institute for Research in Computer Science and Control Domaine de Voluceau Rocquencourt Le Chesnay 78153France

Current multi-operator image resizing methods succeed in generating impressive results by using image similarity measure to guide the resizing process. An optimal operation path is found in the resizing space. However, their slow resizing speed caused by inefficient computation strategy of the bidirectional patch matching becomes a drawback in practical use. In this paper, we present a novel method to address this problem. By combining seam carving with scaling and cropping, our method can realize content-aware image resizing very fast. We define cost functions combing image energy and dominant color descriptor for all the operators to evaluate the damage to both local image content and global visual effect. Therefore our algorithm can automatically find an optimal sequence of operations to resize the image by using dynamic programming or greedy algorithm. We also extend our algorithm to indirect image resizing which can protect the aspect ratio of the dominant object in an image.

关键词： image resizing multi-operator operator cost indirect resizing