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A Global Group of Friends

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Beijing Review 2024年第29期67卷 26-27页

作者： jean Paul Vargas the Sustainable Development Innovation Laboratory Central American Institute of Public Administration the Center for Historical Research of Central America University of Costa Rica

China's Global Development Initiative(GDI)is emerging as a transformative force in the international *** President Xi Jinping first publicized the conceplal the United Nations General Assembly in September *** its announcemen,the GDT's main components and objectives,aimed at fostering cunnectily and coperation between coninents,hawe atractod workdwide atentin.

关键词： Global foster objectives

Hf元素添加对CuZr基非晶合金动态弛豫的影响

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力学学报 2024年第8期56卷 2282-2293页

作者：朱凡邢光辉 jean-Marc Pelletier 乔吉超西北工业大学力学与土木建筑学院西安710072 东莞市三航军民融合创新研究院广东东莞523808 INSA-Lyon MATEIS UMR5510F-69621 VilleurbanneFrance

考虑到非晶合金具有独特的无序微观结构,其表现出极为复杂的弛豫动力学特性.动态弛豫行为在非晶合金中普遍存在,深刻理解其机制对于解构非晶合金固有的非均匀微观结构至关重要.少量元素的添加是调控非晶合金微观结构有效手段之一.本研... 详细信息

考虑到非晶合金具有独特的无序微观结构,其表现出极为复杂的弛豫动力学特性.动态弛豫行为在非晶合金中普遍存在,深刻理解其机制对于解构非晶合金固有的非均匀微观结构至关重要.少量元素的添加是调控非晶合金微观结构有效手段之一.本研究以玻璃形成能力良好的Cu_(46)Zr_(47-x)Hf_(x)Al_(7)(x=0,8)非晶合金为模型合金,运用动态力学分析方法研究复模量随频率和温度的变化,进而探究Hf元素取代Zr元素对动态弛豫的影响.在动态力学频率谱中,借助准点缺陷理论阐明非晶合金在玻璃转变温度T_(g)以下处于等构型状态,准点缺陷浓度保持恒定;而在T_(g)以上,准点缺陷浓度随温度的上升呈线性增加.Hf元素的添加会降低玻璃体系等构型状态下的准点缺陷浓度,并抑制原子迁移能力.通过获取连续和离散的弛豫时间分布,直观展示了非晶合金的动力学非均匀性特征.在动态力学温度谱中,Hf元素的引入增加了玻璃体系的混合焓,抑制了β弛豫强度.进一步从内耗角度表明,Hf元素的引入不仅提高了与β弛豫相关的基本结构单元的激活难度,还增加了整个β弛豫过程的激活能.

关键词：非晶合金动态弛豫微合金化准点缺陷微观结构非均匀性

New Insights in the Biodegradability and the Ecotoxicological Effects of Solar Products Containing Mineral and Chemical UV-Filters on Marine Zoo- and Phytoplanktons: An in silico and in vitro Study

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Journal of Cosmetics, Dermatological Sciences and Applications 2024年第1期14卷 98-111页

作者： jean-Claude Hubaud Karim Mekideche jean-Eric Branka Luc Lefeuvre HELIOSCIENCE Cité de la cosmétique 2 rue Odette Jasse Marseille France EPHYSCIENCE 498ter route de Saint Joseph de Porterie Nantes France Laboratoires Dermatologiques d’Uriage Neuilly-sur-Seine France

Background: Cosmetic formulations, and particularly solar products which contain mineral and chemical UV-filters, are often suspected of causing harmful effects on marine fauna and flora. After the publication of our work in 2019 concerning the ecotoxicological effects of such formulations on corals (Seriatopora hystrix), we here provide some new information about the biodegradability and the ecotoxicological effects of these products on marine zoo- and phytoplankton. Therefore, we choose to realize in silico and in vitro studies of the biodegradability of several solar products but also to evaluate the ecotoxicological effects of these products on one phytoplankton, i.e. Phaeodactylum tricornutum, and one zooplankton, i.e. Acartia tonsa, of a great importance for sea species survival (notably as sources of food). Materials and methods: Two different approaches were used to study the biodegradability of the tested products: One in silico method and an in vitro one. 2 solar products were involved in the in silico study which consisted in the determination of the degradation factor (DF) of each ingredient of the tested formulas in order to finally obtain their estimated biodegradability percentage. Already available data concerning each ingredient coupled to a computer model developed with one of our partners were used to achieve this study. The in vitro study involved 8 formulas containing UV-filters and was led by following the OECD 301 F guidelines. Ecotoxicological studies of 7 of the formulas containing UV-filters were for their part realized by following the ISO 10253 guidelines for the experiments led with Phaeodactylum tricornutum, and the ISO 14669 guidelines for the experiments led with Acartia tonsa. In these studies, the effect of each tested product on crustaceans’ mortality and algal growth inhibition was assessed. Results: The in silico study predicted that formulas containing chemical UV-filters display a high biodegradability (superior to the threshol

关键词： UV-Filters Chemical UV-Filter Biodegradability Ecotoxicology in silico in vitro Zooplankton Phytoplankton Phaeodactylum tricornutum Acartia tonsa

Interleukin-mediated therapies in liver diseases and comorbidity effects

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World Journal of Hepatology 2024年第7期16卷 980-989页

作者： Nouhoum Bouare jean Delwaide Department of Quality HygienBiosafety/Biosecurity and PharmacovigilenceNational Institute of Public HealthBamako 1771Mali Department of Gastroenterology and Hepatology CHULiegeLiege 4000Belgium

Cytokines like interleukins(ILs)play important roles in inflammation and innate *** and Zhang carried out an interesting study related to ILs and hepatic *** described the role of ILs in the pathogenesis and resolution of hepatic *** authors summarized alcohol-related liver disease and virus-induced hepatitis,as far as clinical studies a fortiori carried out on ILmediated treatments pertaining to these *** editorial contributes to the review by Yang and Zhang titled,"Interleukins in liver disease treatment",and focuses on therapies mediated by ILs in comorbid liver *** documentary search was conducted on recent pertinent literature,primarily using the Google Scholar and PubMed databases.

关键词： Cytokines Interleukins Liver diseases Therapy Comorbidity

Virtual brain twins: from basic neuroscience to clinical use

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National Science Review 2024年第5期11卷 72-86页

作者： Huifang E.Wang Paul Triebkorn Martin Breyton Borana Dollomaja jean-Didier Lemarechal Spase Petkoski Pierpaolo Sorrentino Damien Depannemaecker Meysam Hashemi Viktor K.Jirsa Aix Marseille Université Institut National de la Santéet de la Recherche Médicale Institut de Neurosciences des Systèmes(INS) UMR1106 Service de Pharmacologie Clinique et Pharmacosurveillance AP–HM

Virtual brain twins are personalized, generative and adaptive brain models based on data from an individual's brain for scientific and clinical use. After a description of the key elements of virtual brain twins,we present the standard model for personalized whole-brain network models. The personalization is accomplished using a subject's brain imaging data by three means:(1) assemble cortical and subcortical areas in the subject-specific brain space;(2) directly map connectivity into the brain models, which can be generalized to other parameters; and(3) estimate relevant parameters through model inversion, typically using probabilistic machine learning. We present the use of personalized whole-brain network models in healthy ageing and five clinical diseases: epilepsy, Alzheimer's disease, multiple sclerosis, Parkinson's disease and psychiatric disorders. Specifically, we introduce spatial masks for relevant parameters and demonstrate their use based on the physiological and pathophysiological hypotheses. Finally, we pinpoint the key challenges and future directions.

关键词： virtual brain twin personalized modeling inference neuroscience brain disorder

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Sustainable Ride

ChinAfrica 2024年第9期16卷 54-55页

作者： jean D’AMOUR MBONYINSHUTI 不详

Chinese electric vehicle makers fuel Rwanda’s drive for pollution-free *** a growing demand to electrify Rwanda’s public transport,companies are rushing into the sector to import electric vehicles(EVs)and related se... 详细信息

关键词： companies Sustainable China.

Joint Management of Shared Resources, Issues and Conflicts of the Nso and Oku Tribes in the Ngongbaa Montane Forest Area, NWR of Cameroon

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Natural Resources 2024年第6期15卷 149-172页

作者： jean-Louis Tatah Elvis Kah Department of Geography Faculty of Arts Letters and Social Sciences University of Yaounde I Yaounde Cameroon School of Geology and Mining Engineering University of Ngaoundere Ngaoundere Cameroon

Wherever people live together in or near homelands that harbour joint natural resources such as forest, water, minerals, oil etc., they must collaborate, co-exist and share these resources irrespective of their genetic, social, cultural, and political peculiarities. This is not always the case when self-interest, ethnic divisions, elitist politics, economic interest and power tussle set in. The Nso and Oku people who reside in the Ngongbaa Forest area constitute an example of joint management of resources where at one period, their relationship over the management of the Oku Mountain Forest was cordial and at another, the relationship became conflictive. This study was designed to study the influence of the KIFP forest management policies on the Nso indigenous forest Management system in Ngongbaa Forest, and its implications. The data collected for the study was secured through the administration of a questionnaire to residents of 10 villages adjacent to the Ngongbaa Forest, and forest users who carried out livelihood activities there between 1963 and 2015. These forest user groups include beekeepers, rat trappers, grazers, mushroom gatherers, ground honey/tree honey harvesters, carvers, etc. The investigation also extended to the traditional leaders of Nso and Oku who are in charge of the land tenure systems. The findings show that the Oku Mountain Forest is jointly owned by the Nso and Oku people. The Nso own the eastern half of the forest known as Ngongbaa Forest while the Oku own the western half, known as the Kilum Forest. The cordial relationship that existed between these people ensured the conservation of the forest. But the conflicts that later set in, especially due to the creation of the Kilum Mountain Forest Project in 1987 later changed to the Kilum Ijim Forest Project (KIFP) in 1992 sidelined the local communities which was contrary to the dispositions of the new Cameroon forest law enacted in 1994. Thus, the indigenous conservation practices became ig

关键词： Conflict Joint Management Shared Resources Ngongbaa Kilum Conservation

Gravity tectonics controls on reservoir-scale sandbodies:Insights from 3D seismic geomorphology of the canyons buried in the upper slope of the Eastern Niger delta basin

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Energy Geoscience 2024年第3期5卷 244-260页

作者： Vivian O.Oguadinma jean-Yves Reynaud Vincent Delhaye-Prat Tony Akpi Scott Thackrey Ademola Lanisa Massimo Dall’Asta Univ.Lille CNRSUniv.Littoral Côte d'OpaleUMR 8187LOGLaboratoire d'Océanologie et de GéosciencesF 59000 LilleFrance Total Energies E&P Africa-HUB CSTJFAvenue Larribau64000PauFrance

High-resolution 3D seismic data analysis was integrated with a calibrated well and biostratigraphy data to present the first overview of a buried Pleistocene canyon system on the upper slope of the eastern Niger Delta,the Galabor *** maps of specific horizons allow documenting the changing morphologies and infill lithologies of two main branches of the canyon through two stages of activity separated by a reference horizon dated at 0.99 Ma based on well *** the upper slope,growth faults dissect the canyon heads,the catchment of which encroaches a network of valleys incised on the outer *** canyon fill is composed of muddy channels and mass-transport deposits,largely derived from the collapse of canyon walls and sand-rich bodies forming a tract sourced by shelf-edge deltas at the outlet of the incised ***-density turbiditic processes likely control the distribution of sand bodies along the canyon,ranging from tributary fans on the upper slope to 6 km-wide meander belts on the middle *** sandy deposits accumulate in minibasins formed along the canyon path,downstream of the subsiding hanging wall of the growth faults and upstream of shale ridges that damp the flow in the *** results show that canyons can be major targets for sand reservoir exploration on the upper slope of large muddy deltas.

关键词： Geomorphology Submarine canyon 3D seismic Fault Shale ridge Reservoir Channel

Pulsed lavage in joint arthroplasty: A systematic review and metaanalysis

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World Journal of Orthopedics 2024年第3期15卷 293-301页

作者： Mohammad Daher Gaby Haykal Marven Aoun Marc Moussallem Ali Ghoul jean Tarchichi Amer Sebaaly Department of Orthopedics Saint Joseph UniversityBeirut 1001Lebanon

BACKGROUND Knee and hip osteoarthritis affects millions of people around the world and is expected to rise even more in frequency as the population *** arthroplasty is the surgical management of choice in these *** ossi-fication and radiolucent lines formation are two frequent problems faced in hip and knee replacements *** studies show that the usage of pulsed lavage may prevent their *** To compare pulsed lavage to standard lavage in joint *** PubMed,Cochrane,and Google Scholar(page 1-20)were searched till December *** comparative studies were *** clinical outcomes evaluated were the heterotopic ossification formation in hip replacements,radiolucent lines formation,and functional knee scores in knee *** Four studies met the inclusion criteria and were included in this *** lavage was shown to reduce the formation of radiolucent lines(P=0.001).However,no difference was seen in the remaining outcomes CONCLUSION Pulsed lavage reduced the formation of radiolucent lines in knee *** difference was seen in the remaining ***,the clinical significance of these radiolucent lines is poorly *** conducted randomized controlled studies and cost-effectivity studies are needed to reinforce these findings.

关键词： Knee arthroplasty Hip arthroplasty Pulsed lavage Syringe lavage Heterotopic ossification Radiolucent lines