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Superconductivity above 70 K observed in lutetium polyhydrides

Science China(Physics,Mechanics & Astronomy) 2023年第6期66卷 95-100页

作者： Zhiwen Li Xin He Changling Zhang Ke Lu Baosen Min Jun Zhang Sijia Zhang Jianfa Zhao Luchuan Shi Yi Peng Shaomin Feng Zheng deng Jing Song Qingqing Liu Xiancheng Wang Richeng Yu Luhong Wang Yingzhe Li jay d.bass Vitali Prakapenka Stella Chariton Haozhe Liu Changqing Jin Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing100190China Songshan Lake Materials Laboratory Dongguan523808China Shanghai Advanced Research in Physical Sciences Shanghai201203China department of Geology University of Illinois at Urbana ChampaignUrbana61801USA Center for Advanced Radiations Sources University of ChicagoChicago60637USA Center for High Pressure Science&Technology Advanced Research Beijing100094China

The binary polyhydrides of heavy rare earth lutetium that shares a similar valence electron configuration to lanthanum have been experimentally discovered to be *** lutetium polyhydrides were successfully synthesized at high pressure and high temperature conditions using a diamond anvil cell in combinations with the in-situ high pressure laser heating *** resistance measurements as a function of temperature were performed at the same pressure of synthesis in order to study the transitions of superconductivity(SC).The superconducting transition with a maximum onset temperature(Tc)71 K was observed at pressure of 218 GPa in the *** Tcdecreased to 65 K when pressure was at 181 *** the evolution of SC at applied magnetic fields,the upper critical field at zero temperatureμ0Hc2(0)was obtained to be~36 *** in-situ high pressure X-ray diffraction experiments imply that the high TcSC should arise from the Lu4H23phase with Pm3n symmetry that forms a new type of hydrogen cage framework different from those reported for previous light rare earth polyhydride superconductors.

关键词： lutetium polyhydrides superconductors at high pressures high pressure synthesis

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Carbene chemistry for unnatural biosynthesis

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Science China(Life Sciences) 2024年第1期67卷 204-207页

作者： Jing Huang jay d.Keasling department of Chemical and Biomolecular Engineering University of CaliforniaBerkeley 94720USA Joint BioEnergy Institute Lawrence Berkeley National LaboratoryEmeryville 94608USA Biological Systems and Engineering division Lawrence Berkeley National LaboratoryBerkeley 94720USA Novo Nordisk Foundation Center for Biosustainability Technical University of DenmarkKongens Lyngby 2800Denmark department of Bioengineering University of CaliforniaBerkeley 94720USA Synthetic Biochemistry Center Institute for Synthetic BiologyShenzhen Institutes for Advanced TechnologiesShenzhen 518055China

Previously,chemists working in synthesis were jealous of biologists since the enzymes found in nature usually exhibited great catalytic properties(e.g.,high catalytic efficiency,excellent selectivity such as substrate selectivity,regioselectivity and stereoselectivity).However,biological systems lack many counterparts of reactions widely used in chemical synthesis.

关键词： synthesis selectivity catalytic

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矿物和熔体物理学

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宝石和宝石学杂志(中英文) 1988年第4期 1-7页

作者： jay d.bass 阎永林朱德玉

概述在过去的四年里,矿物物理学界可谓是发现颇丰,进展很大,各家争鸣.要强调这一点,可列举出在很多领域中美国科研努力所取得的一些重大成就.相对新的实验方法已迅速变得成熟并已开始产生出极为重要的成果.一个突出的例子是用市里渊光... 详细信息

概述在过去的四年里,矿物物理学界可谓是发现颇丰,进展很大,各家争鸣.要强调这一点,可列举出在很多领域中美国科研努力所取得的一些重大成就.相对新的实验方法已迅速变得成熟并已开始产生出极为重要的成果.一个突出的例子是用市里渊光谱学来测量镁橄榄石的β和γ高压相的弹性系数.更多已成型的技术方法的能力得到相当大的发展,其中一个明显的例子是用钻石高压腔来保持静压力550GPa(5.5Mbar)——该压力大大超过了地球中

关键词：矿物化合物高压腔钻石岛状硅酸盐矿物同质多象变体弹性模量体积模量高压相变电器构件熔体

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Honey vesicle-like nanoparticles protect aged liver from non-alcoholic steatohepatitis

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3661-3679页

作者： Baolong Liu Phuong Linh Nguyen Han Yu Xingzhi Li Huiren Wang Tram Gia Bao Nguyen Prakash Kumar Sahoo Meghna Sur jay Reddy Sarah Sillman Stephen d.Kachman Bara Altartouri Guoqing Lu Sathish Kumar Natarajan Mahesh Pattabiraman Jiujiu Yu department of Nutrition and Health Sciences University of Nebraska-LincolnLincolnNE 68583USA Shaanxi Key Laboratory of Molecular Biology for Agriculture College of Animal Science and TechnologyNorthwest A&F UniversityYangling 712100China department of Nutrition Case Western Reserve UniversityClevelandOH 44106USA School of Veterinary Medicine and Biomedical Sciences University of Nebraska-LincolnLincolnNE 68583USA department of Statistics University of Nebraska-LincolnLincolnNE 68583USA Center for Biotechnology University of Nebraska-LincolnLincolnNE 68588USA department of Biology University of Nebraska OmahaOmahaNE 68182USA department of Chemistry University of Nebraska-KearneyKearneyNE 68849USA

Non-alcoholic steatohepatitis(NASH),an advanced form of non-alcoholic fatty liver disease(NAFLd),has emerged as the leading cause of liver failure and related ***,no medication is specifically approved to treat NAFLd or *** we report that oral administration of honey vesiclelike nanoparticles(H-VLNs)to naturally aged mice protects the liver from NASH development.H-VLNs are dominantly taken up by Kupffer cells in the liver and suppress hepatic chronic inflammation and further development of fibrosis and nodule formation in aged *** their reported antiinflammasome function,H-VLNs are found to inhibit the transcriptional activities of C-JUN and nuclear factor-kappa B(NF-κB).MicroRNAs miR5119 and miR5108 and phenolic compound luteolin in H-VLNs are identified in suppressing both the C-JUN and NF-kB ***,oral intake of H-VLNs represents a promising new user-friendly modality to prevent the development of NASH.

关键词： Honey Extracellular vesicles Exosomes Nanoparticles microRNAs Aging Inflammation Non-alcoholic steatohepatitis

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Adding Value to Crop Production Systems by Integrating Forage Cover Crop Grazing

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American Journal of Plant Sciences 2024年第3期15卷 180-192页

作者： Robert B. Mitchell daren d. Redfearn Kenneth P. Vogel Terry J. Klopfenstein Galen Erickson P. Stephen Baenziger Bruce E. Anderson Mary E. drewnoski jay Parsons Steven d. Masterson Marty R. Schmer Virginia L. Jin USdA-ARS Wheat Sorghum and Forage Research Unit University of Nebraska-Lincoln Lincoln NE USA department of Agronomy and Horticulture University of Nebraska-Lincoln Lincoln NE USA department of Animal Science University of Nebraska-Lincoln Lincoln NE USA department of Agricultural Economics University of Nebraska-Lincoln Lincoln NE USA USdA-ARS Agroecosystem Management Research Unit University of Nebraska-Lincoln Lincoln NE USA

In addition to their value as cereal grains, wheat (Triticum aestivum L.) and triticale (× Triticosecale Wittmack) are important cool-season annual forages and cover crops. Yearling steer (Bos taurus) performance was compared in the spring following autumn establishment as for age cover crops after soybean [Glycine max (L.) Merr.] grain harvest. Replicated pastures (0.4 ha) were no-till seeded in three consecutive years into soybean stubble in autumn, fertilized, and grazed the following spring near Ithaca, NE, USA. Each pasture (n = 3) was continuously stocked in spring with four yearling steers (380 ± 38 kg) for 17, 32, and 28 d in 2005, 2006, and 2007, respectively. In 2005, average daily gain (AdG) for steers grazing triticale exceeded the AdG for wheat by 0.31 kghd-1d-1. In 2006, wheat AdG exceeded that for triticale by 0.12 kghd-1d-1. In 2007, steers grazing wheat lost weight, while steers grazing triticale gained 0.20 kghd-1d-1. Based on the 3-year average animal gains valued at $1.32 kg-1, mean net return ($ ha-1 yr-1) was $62.15 for triticale and $22.55 for wheat. Since these grazed cover crops provide ecosystem services in addition to forage, grazing could be viewed as a mechanism for recovering costs and adds additional value to the system. Based on this 3-year grazing trial, triticale was superior to wheat and likely will provide the most stable beef yearling performance across years with variable weather for the western Cornbelt USA.

关键词： Cover crops Soybean Triticale Wheat

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Chowing down:diet considerations in rodent models of metabolic disease

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Life Metabolism 2023年第3期2卷 10-18页

作者： Kevin C.Klatt Kevin bass John R.Speakman Kevin d.Hall department of Nutritional Sciences and Toxicology University of California BerkeleyBerkeleyCA 94720United States Garrison Institute of Aging Texas Tech University Health Science CenterLubbockTX 79430United States Center for Energy Metabolism and Reproduction Shenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China National Institute of diabetes and digestive and Kidney diseases National Institutes of HealthBethesdaMD 20892United States

diet plays a substantial role in the etiology, progression, and treatment of chronic disease and is best considered as a multifacetedset of modifiable input variables with pleiotropic effects on a variety of biological pathways spanning multiple organ systems. Thisbrief review discusses key issues related to the design and conduct of diet interventions in rodent models of metabolic disease andtheir implications for interpreting experiments. We also make specific recommendations to improve rodent diet studies to help betterunderstand the role of diet on metabolic physiology and thereby improve our understanding of metabolic disease.

关键词： diet composition nutrition chow study design recommendations

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A FAIR-compliant parts catalogue for genome engineering and expression control in Saccharomyces cerevisiae

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Synthetic and Systems Biotechnology 2022年第2期7卷 657-663页

作者： Vasil d’Ambrosio Lea G.Hansen Jie Zhang Emil d.Jensen dushica Arsovska Marcos Laloux Tadas Jakociunas Pernille Hjort davide de Lucrezia Serena Marletta jay d.Keasling Michael K.Jensen Novo Nordisk Foundation Center for Biosustainability Technical University of DenmarkKgs.LyngbyDenmark Explora Biotech Srl Italy Joint BioEnergy Institute EmeryvilleCAUSA Biological Systems and Engineering division Lawrence Berkeley National LaboratoryBerkeleyCAUSA department of Chemical and Biomolecular Engineering Department of BioengineeringUniversity of CaliforniaBerkeleyCAUSA Center for Synthetic Biochemistry Institute for Synthetic BiologyShenzhen Institutes of Advanced TechnologiesShenzhenChina

The synthetic biology toolkit for baker’s yeast,Saccharomyces cerevisiae,includes extensive genome engineering toolkits and parts ***,with the increasing complexity of engineering tasks and versatile applications of this model eukaryote,there is a continued interest to expand and diversify the rational engineering capabilities in this chassis by FAIR(findable,accessible,interoperable,and reproducible)*** this study,we designed and characterised 41 synthetic guide RNA sequences to expand the CRISPR-based genome engineering capabilities for easy and efficient replacement of genomically encoded ***,we characterize in high temporal resolution 20 native promoters and 18 terminators using fluorescein and LUdOX CL-X as references for GFP expression and Od600 measurements,***,all data and reported analysis is provided in a publicly accessible jupyter notebook providing a tool for researchers with low-coding skills to further explore the generated data as well as a template for researchers to write their own *** expect the data,parts,and databases associated with this study to support a FAIR-compliant resource for further advancing the engineering of yeasts.

关键词： gRNA Promoter Terminator Yeast Standardization

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Biodegradation of alkylates under less agitated aquifer conditions

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Journal of Environmental Sciences 2013年第8期25卷 1529-1538页

作者： jay J. Cho Makram T. Suidan Albert d. Venosa URS Corporation 7720N 16th St. Ste 100 Phoenix AZ 85020 USA Faculty of Engineering and Architecture American University of Beirut Dean's officeP.O.Box 11-0236 Riad El Solh 1107 2020 Beirut Lebanon US Environmental Protection Agency National Risk Management Research LaboratoryCincinnati OH 45268 USA

The biodegradability of three alkylates （2,3-dimethylpentane, 2,4-dimethylpentane and 2,2,4-trimethylpentane） under less agitated aquifer conditions was investigated in this study. All three alkylates biodegraded completely under these conditions regardless of the presence or absence of ethanol or benzene, toluene, ethylbenzene, and xylenes （BTEX） in the feed. In the presence of ethanol, alkylates degradation was not inhibited by ethanol. However, alkylates degraded more slowly in the presence of BTEX suggesting competitive inhibition to microbial utilization of alkylates. In the sterile controls, alkylates concentrations remained unchanged throughout the experiments.

关键词： biodegradation alkylates inhibition BTEX ethanol

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Significant methodologic variations in calculating renal function changes following kidney tumor surgery:A quality reporting issue?

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World Journal of Clinical Oncology 2015年第5期6卷 89-91页

作者： Ruth d Blum jay d Raman division of Urology Penn State Milton S.Hershey Medical Center

Renal tumor surgery places patients at increased risk for chronic kidney disease(CKd). Accurate quantification of kidney function changes before and after surgery is essential to determine the magnitude of decline attributable to an index procedure. Current literature, however, highlights heterogeneity and inconsistencies in measurement techniques thereby contributing to ambiguity amongst studies. Further efforts are necessary to standardize reporting of kidney function outcomes related to renal surgery.

关键词： Radical nephrectomy Partial nephrectomy Nephroureterectomy Glomerular filtration rate Chronic kidney disease

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Comparative susceptibility and immune responses of Asian and European honey bees to the American foulbrood pathogen, Paenibacillus larvae

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Insect Science 2019年第5期26卷 831-842页

作者： Sasiprapa Krongdang jay d.Evans Yanping Chen Wannapha Mookhploy Panuwan Chantawannakul 1Bee Protection Laboratory Department of BiologyFaculty of ScienceChiang Mai UniversityChiang MaiThailand Interdisciplinary Program in Biotechnology Graduate SchoolChiang Mai UniversityChiang MaiThailand USdA-ARS Bee Research LaboratoryBeltsvilleMarylandUSA Environmental Science Research Center Faculty of ScienceChiang Mai UniversityChiang MaiThailand

American foulbrood (AFB) disease is caused by Paenibacillus larvae. Currently, this pathogen is widespread in the European honey bee— Apis mellifera. However, little is known about infectivity and pathogenicity of P. lan'ae in the Asiatic cavity-nesting honey bees, Apis cerana. Moreover, comparative knowledge of P. larvae infectivity and pathogenicity between both honey bee species is scarce. In this study, we examined susceptibility, larval mortality, survival rate and expression of genes encoding antimicrobial peptides (AMPs) including defensin, apidaecin, abaecin, and hymenoptaecin in A. mellifera and A. cerana when infected with P. larvae. Our results showed similar effects of P. larvae on the survival rate and patterns of AMP gene expression in both honey bee species when bee larvae are infected with spores at the median lethal concentration (LC5 0 ) for A. mellifera. All AMPs of infected bee larvae showed significant upregulation compared with noninfected bee larvae in both honey bee species. However, larvae of A. cerana were more susceptible than A. mellifera when the same larval ages and spore concentration of P. larvae were used. It also appears that A. cerana showed higher levels of AMP expression than A. mellifera. This research provides the first evidence of survival rate, LC50 and immune response profiles of Asian honey bees, A. cerana, when infected by P. larvae in comparison with the European honey bee, A. mellifera.

关键词： Apis cerana Apis mellifera honey bee immune gene Paenibacillus larvae susceptibility

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