检索结果-南通市图书馆

Binary Fruit Fly Swarm Algorithms for the Set Covering Problem

Computers, Materials & Continua 2022年第6期71卷 4295-4318页

作者： Broderick Crawford Ricardo Soto Hanns de la Fuente Mella Claudio Elortegui Wenceslao Palma Claudio Torres-Rojas Claudia Vasconcellos-Gaete Marcelo Becerra javier pena Sanjay Misra Pontificia Universidad Católica de Valparaíso Valparaíso2362807Chile LERIA Universitéd’AngersAngers49000France Department of Computer Science and Communication Ostfold University CollegeHaldenNorway

Currently,the industry is experiencing an exponential increase in dealing with binary-based combinatorial *** this sense,metaheuristics have been a common trend in the field in order to design approaches to solve them ***,a well-known strategy consists in the use of algorithms based on discrete swarms transformed to perform in binary *** the No Free Lunch theorem,we are interested in testing the performance of the Fruit Fly Algorithm,this is a bio-inspired metaheuristic for deducing global optimization in continuous spaces,based on the foraging behavior of the fruit fly,which usually has much better sensory perception of smell and vision than any other *** the other hand,the Set Coverage Problem is a well-known NP-hard problem with many practical applications,including production line balancing,utility installation,and crew scheduling in railroad and mass transit *** this paper,we propose different binarization methods for the Fruit Fly Algorithm,using Sshaped and V-shaped transfer functions and various discretization methods to make the algorithm work in a binary search *** are motivated with this approach,because in this way we can deliver to future researchers interested in this area,a way to be able to work with continuous metaheuristics in binary *** new approach was tested on benchmark instances of the Set Coverage Problem and the computational results show that the proposed algorithm is robust enough to produce good results with low computational cost.

关键词： Set covering problem fruit fly swarm algorithm metaheuristics binarization methods combinatorial optimization problem

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Efficacy of cognitive rehabilitation in Parkinson's disease

引用

Neural Regeneration Research 2018年第2期13卷 226-227页

作者： María Díez-Cirarda Naroa Ibarretxe-Bilbao javier pena Natalia Ojeda Department of methods and experimental psychology faculty of psychology and educationuniversity of deustoBasque CountrySpain

Cognitive rehabilitation is a potential and promising treatment for cognitive impairment in Parkinson＇s disease （PD） that has shown efficacy in diverse studies. In addition, some few studies have found brain changes after cognitive rehabilitation in PD, which supports the existence of brain plasticity associated to cognitive training in a degen- erative disease.

关键词： PD Efficacy of cognitive rehabilitation in Parkinson’s disease

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Auditory function in symptomatic patients recovered from SARS-CoV-2 and unexposed patients:An analytical cross-sectional study

引用

Journal of Otology 2023年第3期18卷 118-124页

作者： Katherin Andrea Borda Pedraza Sergio Mauricio Moreno Lopez javier Amaya-Nieto Liliana Akli Serpa Ginna Paola Saavedra Martínez Mauricio Ernesto Quinche Pardo Alberto pena Valenzuela Otorhinolaryngology Department Universidad Nacional ColombiaColombia Epidemiology Department Universidad de Los AndesColombia Health Systems and Services Research Group Universidad Nacional de ColombiaBogotaColombia Audiology Department Universidad Nacional de ColombiaColombia Health and Social Protection Ministry Colombia Universidad Nacional Colombia Colombia Otorhinolaryngology Department Universidad Nacional de ColombiaColombia

Objective:To describe audiological symptoms,audiometric profile,and distortion product otoacoustic emission in symptomatic patients recovering from SARS-CoV-2 infection(positive RT-PCR test)and asymptomatic patients(negative RT-PCR test).Methods:An analytical cross-sectional study was conducted using data obtained from clinical charts,physical examination,audiometry,and distortion product otoacoustic emission on 40 patients[case patients(CP)]recovering from SARS-CoV-2 infection diagnosed by a positive RT-PCR test and 22asymptomatic participants with a negative RT-PCR test[non-case(NC)].Results:Sixty-two patients(mean age:31.1 and 28.2 years in the CP and NC groups,respectively)were *** participants were young without significant comorbidities,risk factors for hearing loss or otological ***(5%),tinnitus(17.5%)and aural fullness/hearing loss(35%)were found in the CP group.A statistically significant difference was found in specific frequencies(1000,4000,and 8000 Hz)and pure tone average(low and high conversational frequencies with increased threshold in the PC group compared with the NC group),which was not found in distortion product otoacoustic ***:Audiovestibular symptoms are frequent in symptomatic patients recovering from SARS-CoV-2 ***-CoV-2 infection was consistently associated with an increased audiometric hearing threshold at specific frequencies and low tone average.

关键词： SARS-CoV-2 Cochlear diseases Pure tone audiometry Otoacoustic emissions Hearing loss Otological symptoms

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gastrointestinal stromal tumors:a multidisciplinary challenge

引用

World Journal of Gastroenterology 2018年第18期24卷 1925-1941页

作者： Juan Manuel Sanchez-Hidalgo Manuel Duran-Martinez Rafael Molero-Payan Sebastian Rufian-pena Alvaro Arjona-Sanchez Angela Casado-Adam Antonio Cosano-Alvarez javier Briceno-Delgado Department of General and Digestive Surgery Reina Sofia University HospitalAvda.Menéndez Pidal s/nCordoba 14004Spain Department of Intern Medicine Reina Sofia University HospitalAvda.Menéndez Pidal s/nCordoba 14004Spain Lipids and Atherosclerosis Research Unit IMIBIC/Hospital Universitario Reina Sofía/Universidad de CórdobaCordoba 14004Spain

Gastrointestinal stromal tumors(GISTs) are the most common mesenchymal tumors located in the alimentary tract. Its usual manifestation is gastrointestinal bleeding. However, small asymptomatic lesions are frequently detected as incidental finding. Characteristically, most GISTs(> 95%) are positive for the KIT protein(CD117) by IHC staining and approximately 80%-90% of GISTs carry a mutation in the c-KIT or PDGFRA genes. Mutational analysis should be performed when planning adjuvant and neoadjuvant therapy, due to its possible resistance to conventional treatment. The arise of tyrosine kinase inhibitor has supposed a revolution in GISTs treatment being useful as adjuvant, neoadjuvant or recurrence disease treatment. That is why a multidisciplinary approach to this disease is required. The correct characterization of the tumor at diagnosis(the diagnosis of recurrences and the evaluation of the response to treatment with tyrosine kinase inhibitors) is fundamental for facing these tumors and requires specialized Endoscopist, Radiologists and Nuclear Medicine Physician. Surgery is the only potentially curative treatment for suspected resectable GIST. In the case of high risk GISTs, surgery plus adjuvantImatinib-Mesylate for 3 years is the standard treatment. Neoadjuvant imatinib-mesylate should be considered to shrink the tumor in case of locally advanced primary or recurrence disease, unresectable or potentially resectable metastasic tumors, and potentially resectable disease in complex anatomic locations to decrease the related morbidity. In the case of Metastatic GIST under Neoadjuvant treatment, when there are complete response, stable disease or limited disease progression, complete cytoreductive surgery could be a therapeutic option if feasible.

关键词： Gastrointestinal stromal tumors Surgery Oncology Radiology Endoscopy Nuclear medicine Pathology Disease management Tyrosine kinase inhibitors Gastroenterology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Colorectal peritoneal metastases:Optimal management review

引用

World Journal of Gastroenterology 2019年第27期25卷 3484-3502页

作者： Juan Manuel Sánchez-Hidalgo Lidia Rodríguez-Ortiz Alvaro Arjona-Sánchez Sebastián Rufián-pena Angela Casado-Adam Antonio Cosano-Alvarez javier Briceno-Delgado Department of General and Digestive Surgery Reina Sofia University HospitalCordoba 14004Spain

The peritoneum is a common site of dissemination for colorrectal cancer, with a poorer prognosis than other sites of metastases. In the last two decades, it has been considered as a locoregional disease progression and treated as such with curative intention treatments. Cytoreductive surgery(CRS) and hyperthermic intraperitoneal chemotherapy(HIPEC) is the actual reference treatment for these patients as better survival results have been reached as compared to systemic chemotherapy alone, but its therapeutic efficacy is still under debate. Actual guidelines recommend that the management of colorectal cancer with peritoneal metastases should be led by a multidisciplinary team carried out in experienced centers and consider CRS + HIPEC for selected patients. Accumulative evidence in the last three years suggests that this is a curative treatment that may improve patients disease-free survival, decrease the risk of recurrence, and does not increase the risk of treatment-related mortality. In this review we aim to gather the latest results from referral centers and opinions from experts about the effectiveness and feasibility of CRS + HIPEC for treating peritoneal disease from colorectal malignancies.

关键词： Peritoneal metastases Colorectal cancer Cytoreductive surgery Hyperthermic intraperitoneal chemotherapy Peritoneal carcinomatosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Growth Traits and the Trade-Offs for Tree Species with Arbuscular Mycorrhizal Fungi in a Tropical Rain Forest Edge at Los Tuxtlas,Mexico

引用

Open Journal of Forestry 2015年第2期5卷 181-194页

作者： Juan Carlos pena-Becerril javier Alvarez-Sanchez Guadalupe Barajas-Guzmán Ana María Quiroz-Ayala Departamento de Ecología y Recursos Naturales Facultad de CienciasUniversidad Nacional Autónoma de MéxicoCiudad UniversitariaMexico CityMéxico

The effect of arbuscular mycorrhizal fungi on seedling growth across the rain forest-pasture edge has not received much attention. In a tropical rain forest in eastern Mexico, the seedlings of light demanding (Ficus insipida), nonsecondary light demanding (Lonchocarpus cruentus) and shade tolerant species (Nectandra ambigens, Coccoloba hondurensis) were grown and transplanted to a forest edge with three inoculation treatments (AM fungus spores and colonized roots, spores, and no inoculum). For all species, stem height, stem diameter, total dry weight, leaf area and net assimilation rate were higher in the pasture. Stem height, stem diameter and root/shoot were higher for L. cruentus, and leaf area ratio, specific leaf area and net assimilation rate were higher for F. insipida;the lowest values of almost all variables were recorded for N. ambigens. L. cruentus and C. hondurensis with mycorrhizae had the highest values for root/shoot and net assimilation rate, respectively. The lowest values of root/shoot and net assimilation rate were observed for nonlight-demanding species in the forest. There were clear trade-offs for the pioneer species between survival and growth, and in underground biomass allocation and assimilation for nonsecondary light demanding, but there was not for the shade-tolerant species.

关键词： Arbuscular Mycorrhizal Fungi Edge Forest Tropical Trees Trade-Offs Tropical Rain Forest

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pharmacological inhibition of cannabinoid receptor 1 stimulates gastric release of nesfatin-1 via the mTOR pathway

引用

World Journal of Gastroenterology 2017年第35期23卷 6403-6411页

作者： Cintia Folgueira Silvia Barja-Fernandez Laura Prado Omar Al-Massadi Cecilia Castelao Veronica pena-Leon Patricia Gonzalez-Saenz javier Baltar Ivan Baamonde Rosaura Leis Carlos Dieguez Uberto Pagotto Felipe F Casanueva Sulay A Tovar Ruben Nogueiras Luisa M Seoane Grupo Fisiopatología Endocrina Instituto de Investigación Sanitaria de Santiago de Compostela CIBER Fisiopatología Obesidad y Nutrición Instituto de Salud Carlos III Department of Physiology Research Centre of Molecular Medicine and Chronic Diseases Department of Pediatric Universidad de Santiago de Compostela Servicio de Cirugía General Complexo Hospitalario Universitario de Santiago Endocrinology Unit and Center for Applied Biomedical Research Department of Medical and Surgical SciencesHospital S.Orsola-MalpighiAlma Mater University of Bologna Laboratorio de Endocrinología Molecular y Celular.Universidad de Santiago de Compostela Instituto de Investigación Sanitaria de Santiago de CompostelaComplexo Hospitalario Universitario de Santiago

AIM To determine whether Nucb2/nesfatin1 production is regulated by the cannabinoid system through the intracellular m TOR pathway in the *** Sprague Dawley rats were treated with vehicle, rimonabant, rapamycin or rapamycin+rimonabant. Gastric tissue obtained from the animals was used for biochemical assays: Nucb2 m RNA measurement by real time PCR, gastric Nucb2/nesfatin protein content by western blot, and gastric explants to obtain gastric secretomes. Nucb2/nesfatin levels were measured in gastric secretomes and plasma using enzyme-linked immunosorbent assay. RESULTS The inhibition of cannabinoid receptor 1(CB1) by the peripheral injection of an inverse agonist, namely rimonabant, decreases food intake and increases the gastric secretion and circulating levels of Nucb2/nesfatin-1. In addition, rimonabant treatment activates m TOR pathway in the stomach as showed by the increase in pm TOR/m TOR expression in gastric tissue obtained from rimonabant treated animals. These effects were confirmed by the use of a CB1 antagonist, AM281. When the intracellular pathway m TOR/S6 k was inactivated by chronic treatment with rapamycin, rimonabant treatment was no longer able to stimulate the gastric secretion of Nucb2/*** The peripheral cannabinoid system regulates food intake through a mechanism that implies gastric production and release of Nucb2/Nesfatin-1, which is mediated by the m TOR/S6 k pathway.

关键词： NUCB2/nesfatin-1 Stomach Food intake Cannabinoid receptor 1 mTOR

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：