检索结果-南通市图书馆

Bioactive Materials 2022年第8期7卷 302-312页

作者： Adam M.Navara Yu Seon Kim Yilan Xu Christopher l.Crafton Mani Diba jason l.guo Antonios G.Mikos Department of Bioengineering Rice University6500 Main StreetHoustonTX77030USA

Extrusion bioprinting is a popular method for fabricating tissue engineering scaffolds because of its potential to rapidly produce complex,bioactive or cell-laden ***,due to the relatively high viscosity required to maintain shape fidelity during printing,many extrusion-based inks lack the ability to achieve precise structures at scales lower than hundreds of *** this work,we present a novel poly(N-isopropylacrylamide)(PNIPAAm)-based ink and poloxamer support bath system that produces precise,multi-layered structures on the tens of micrometers *** support bath maintains the structure of the ink in a hydrated,heated environment ideal for cell culture,while the ink undergoes rapid thermogelation followed by a spontaneous covalent crosslinking *** the combination of the PNIPAAm-based ink and poloxamer bath,this system was able to produce hydrogel scaffolds with uniform fibers possessing diameters tunable from 80 to 200μm.A framework of relationships between several important printing factors involved in maintaining support and thermogelation was also *** a whole,this work demonstrates the ability to produce precise,acellular and cell-laden PNIPAAm-based scaffolds at high-resolution and contributes to the growing body of research surrounding the printability of extrusion-based bioinks with support baths.

关键词： Bioprinting Thermogelling macromer Tissue engineering Printability

Evaluating the physicochemical effects of conjugating peptides into thermogelling hydrogels for regenerative biomaterials applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Regenerative Biomaterials 2021年第6期8卷 260-272页

作者： Hannah A.Pearce Emily Y.Jiang Joseph W.R.Swain Adam M.Navara jason l.guo Yu Seon Kim Andrew Woehr Jeffrey D.Hartgerink Antonios G.Mikos Department of Bioengineering Rice University6500 Main StreetHoustonTX 77030USA Depatment of Chemistry Rice University6500 Main StreetHoustonTX 77030USA

Thermogelling hydrogels,such as poly(N-isopropylacrylamide)[P(NiPAAm)],provide tunable constructs leveraged in many regenerative biomaterial ***,our lab developed the crosslinker poly(glycolic acid)-poly(ethylene glycol)-poly(glycolic acid)-di(but-2-yne-1,4-dithiol),which crosslinks P(NiPAAm-co-glycidyl methacrylate)via thiol-epoxy reaction and can be functionalized with azide-terminated peptides via alkyne-azide click *** study’s aim was to evaluate the impact of peptides on the physicochemical properties of the *** physicochemical properties of the hydrogels including the lower critical solution temperature,crosslinking times,swelling,degradation,peptide release and cytocompatibility were *** gels bearing peptides increased equilibrium swelling indicating hydrophilicity of the hydrogel *** sol fractions were found for all groups,indicating that inclusion of peptides does not impact ***,the inclusion of a matrix metalloproteinase-sensitive peptide allowed elucidation of whether release of peptides from the network was driven by hydrolysis or enzymatic *** hydrophilicity of the network determined by the swelling behavior was demonstrated to be the most important factor in dictating hydrogel behavior over *** study demonstrates the importance of characterizing the impact of additives on the physicochemical properties of *** characteristics are key in determining design considerations for future in vitro and in vivo studies for tissue regeneration.

关键词： thermogelling click chemistry hydrogels peptides poly(N-isopropylacrylamide)

OptoGPT: A foundation model for inverse design in optical multilayer thin film structures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Opto-Electronic Advances 2024年第7期7卷 4-16页

作者： Taigao Ma Haozhu Wang l.Jay guo Department of Physics University of MichiganAnn ArborMichigan 48109USA Department of Electrical Engineering and Computer Science University of MichiganAnn ArborMichigan 48109USA

Optical multilayer thin film structures have been widely used in numerous photonic ***,existing inverse design methods have many drawbacks because they either fail to quickly adapt to different design targets,or are difficult to suit for different types of structures,e.g.,designing for different materials at each *** methods also cannot accommodate versatile design situations under different angles and *** addition,how to benefit practical fabrications and manufacturing has not been extensively considered *** this work,we introduce OptoGPT(Opto Generative Pretrained Transformer),a decoder-only transformer,to solve all these drawbacks and issues simultaneously.

关键词： multilayer thin film structure inverse design foundation models deep learning structural color

A Method for Evaluating the Maximum Bending Degree of Flexural Toppling Rock Masses Based on the Rock Tensile Strain-Softening Model

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2024年第4期35卷 1243-1253页

作者： Jiongchao Wang Jun Zheng Jichao guo Qing lü Jianhui Deng Department of Civil Engineering Zhejiang UniversityHangzhou310058China Center for Balance Architecture Zhejiang UniversityHangzhou310007China State Key laboratory of Hydraulics and Mountain River Engineering College of Water Resource and HydropowerSichuan UniversityChengdu610065China

Flexural toppling occurs when a series of layered rock masses bend towards their free *** is important to evaluate the maximum bending degree and the requirement of supports of flexural toppling rock mass to prevent rock mass cracking and even failure leading to a *** on the rock tensile strain-softening model,this study proposes a method for calculating the maximum curvature(C_(ppmax))of flexural toppling rock *** applying this method to calculate Cppmax of 9 types of rock masses with different hardness and rock layer thickness,some conclusions are drawn:(1)the internal key factors affecting C_(ppmax)are E^(⋆)(E^(⋆)=E_(ss)/E_(0),where E_(0)and E_(ss)are the mean deformation moduli of the rock before and after reaching its peak tensile strength,respectively),the strainεt corresponding to the tensile strength of rock,and the thickness(h)of rock layers;(2)hard rock layers are more likely to develop into block toppling than soft rock layers;and(3)thin rock layers are more likely to remain in flexural toppling state than thick rock *** addition,it is found that C_(ppmax)for flexural toppling rock masses composed of bedded rocks such as gneiss is related to the tensile direction.

关键词： flexural toppling rock mass maximum bending degree strain-softening model curvature rock mechanics

Pulsations of Three Rapidly Oscillating Ap Stars TIC 96315731,TIC72392575,and TIC 318007796

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第8期24卷 157-168页

作者： Hai-Jian Zhong Dong-Xiang Shen Chun-Hua Zhu He-lei liu Su-Fen guo guo-liang lü School of Physical Science and Technology Xinjiang UniversityUrumqi 830046China Xinjiang Astronomical Observatory National Astronomical ObservatoriesChinese Academy of SciencesUrumqi 830000China

We analyze the frequencies of three known roAp stars,TIC 96315731,TIC 72392575,and TIC 318007796,using the light curves from the Transiting Exoplanet Survey *** TIC 96315731,the rotational and pulsational frequencies are 0.1498360 day^(-1)and 165.2609 day^(-1),*** the case of TIC 72392575,the rotational frequency is 0.25551 day^(-1).We detect a quintuplet of pulsation frequencies with a center frequency of135.9233 day^(-1),along with two signals within the second pair of rotational sidelobes of the quintuplet separated by the rotation *** two signals may correspond to the frequencies of a dipole *** TIC318007796,the rotational and pulsational frequencies are 0.2475021 day^(-1),192.73995 day^(-1),and196.33065 day^(-1),*** on the oblique pulsator model,we calculate the rotation inclination(i)and magnetic obliquity angle(b)for the stars,which provide the geometry of the pulsation *** the phases of the frequency quintuplets,the pulsation amplitude and phase modulation curves,and the results of spherical harmonic decomposition,we conclude that the pulsation modes of frequency quintuplets in TIC96315731,TIC 72392575,and TIC 318007796 correspond to distorted dipole mode,distorted quadrupole mode,and distorted dipole mode,respectively.

关键词： asteroseismology-techniques photometric-stars oscillations(including pulsations)-stars chemically peculiar

Synthesis,disorder and Ising anisotropy in a new spin liquid candidate PrMgAl_(11)O_(19)

在线全文

学校读者我要写书评

暂无评论

Materials Futures 2024年第3期3卷 148-156页

作者： Yantao Cao Huanpeng Bu Zhendong Fu Jinkui Zhao jason S Gardner Zhongwen Ouyang Zhaoming Tian Zhiwei li Hanjie guo Key lab for Magnetism and Magnetic Materials of the Ministry of Education Lanzhou UniversityLanzhou 730000People’s Republic of China Songshan lake Materials laboratory DongguanGuangdong 523808People’s Republic of China Institute of Physics Chinese Academy of SciencesBeijing 100190People’s Republic of China Materials Science and Technology Division Oak Ridge National LaboratoryOak RidgeTN 37831United States of America School of Physics and Wuhan National High Magnetic Field Center Huazhong University of Science and TechnologyWuhan 430074People’s Republic of China

Here we report the successful synthesis of large single crystals of triangular frustrated PrMgAl_(11)O_(19)using the optical floating zone *** crystal x-ray diffraction(XRD)measurements unveiled the presence of quenched disorder within the mirror plane,specifically~7%of Pr ions deviating from the ideal 2d site towards the 6h *** susceptibility measurements revealed an Ising anisotropy with the c-axis being the easy *** a large spin–spin interaction that develops below~10 K and considerable site disorder,the spins do not order or freeze down to at least 50 *** availability of large single crystals offers a distinct opportunity to investigate the exotic magnetic state on a triangular lattice with an easy axis out of the plane.

关键词： spin liquid disorder frustration triangular lattice Ising anisotropy

Macrocyclic peptides:up-and-coming weapons to combat antimicrobial resistance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第5期9卷 1786-1787页

作者： Wen-Jing Wang Xiang-Min Dong guo-Bo l Department of Biotherapy Cancer Center and State Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengduSichuanChina Key laboratory of Drug Targeting and Drug Delivery System of Ministry of Education Department of Medicinal ChemistryWest China School of PharmacySichuan UniversityChengduSichuanChina

Recently,two companion papers published in Nature reported a first-in-class tethered macrocyclic peptide antibiotic targeting carbapenem-resistant ***(CRAB)and unveiled their unique antibacterial mechanism,which invol... 详细信息

关键词： outer macrocyclic Macrocyclic

Progress in preparation of AlN-reinforced magnesium matrix composites:A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Foundry 2024年第1期21卷 1-10页

作者： lu Chen Shu-lin lü Di-jia Zhao Wei guo Jian-yu li Shu-sen Wu State Key lab of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

As a ceramic material,AlN has very good thermophysical and mechanical *** addition,AlN is an effective refining agent for Mg alloys because it has a lattice constant similar to that of ***,AlN is an ideal reinforcement for magnesium matrix composites(MMCs),and is attracting increasing *** review addresses the development of preparation technologies for AlN-reinforced Mg matrix *** mainstream preparation techniques include stir casting,melt infiltration,powder metallurgy,and in-situ *** addition,the advantages and disadvantages of these techniques are analyzed in depth,and it is pointed out that the next direction for the preparation of high-performance AlN-reinforced MMCs is less aluminization and multiple technologies integration.

关键词： AlN MMCs preparation thermophysical property mechanical property

Electrode particulate materials for advanced rechargeable batteries:A review

在线全文

学校读者我要写书评

暂无评论

Particuology 2024年第3期86卷 160-181页

作者： Mingyang Ma Miao Du Yan liu Hongyan lü Jialin Yang Zelin Hao Jinzhi guo Xinglong Wu MOE Key laboratory for UV light-Emitting Materials and Technology Northeast Normal UniversityChangchunJilin130024China Department of Chemistry Northeast Normal UniversityChangchunJilin130024China

The demand for large-scale energy storage is increasing due to the decreasing non-renewable resources and deteriorating environmental *** rechargeable batteries with high energy density and long cycle performance is an ideal choice to meet the demand of energy storage *** development of excellent electrode particles is of great significance in the commercialization of nextgeneration *** ideal electrode particles should balance raw material reserves,electrochemical performance,price and environmental *** them,the development of electrode particulate materials with excellent electrochemical properties is the top priority at *** this review,the typical researches of electrode materials are summarized in terms of crystal structure,morphology,pore structure,surface and interface ***,the structural characteristics and improvement methods of transition metal oxides,polyanionic compounds,Prussian blue and their analogues are ***,the different effects of particulate morphology,pore,surface and interface structure on the performance of electrode materials are *** designing high-performance electrode materials,preparation route should be set according to the particle properties of the materials and the synergistic effect of various optimization methods should be *** the same time,in addition to the electrode materials,other components of the rechargeable batteries,such as current collector,separator and electrolytes,should be optimized to improve the overall performance of the *** review would provide important guiding principle for designing high-performance electrode particulate materials.

关键词： Particulate properties Electrode materials Rechargeable batteries

Al_(1-x)Sc_(x)Sb_(y)N_(1-y):An opportunity for ferroelectric semiconductor field effect transistor

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2024年第11期67卷 133-140页

作者： Shujin guo Xianghua Kong Hong guo College of Physics and Electronic Engineering Center for Computational SciencesSichuan Normal UniversityChengdu 610068China College of Physics and Optoelectronic Engineering Shenzhen UniversityShenzhen 518060China Department of Physics McGill UniversityMontreal H3A 2T8Canada

For the in-memory computation architecture,a ferroelectric semiconductor field-effect transistor(FeSFET)incorporates ferroelectric material into the FET channel to realize logic and memory in a single *** emerging groupⅢnitride material Al_(1-x)Sc_(x)N provides an excellent platform to explore FeSFET,as this material has significant electric polarization,ferroelectric switching,and high carrier ***,steps need to be taken to reduce the large band gap of~5 eV of Al_(1-x)Sc_(x)N to improve its transport property for in-memory logic *** state-of-the-art first principles analysis,here we predict that alloying a relatively small amount(less than~5%)of Sb impurities into Al_(1-x)Sc_(x)N very effectively reduces the band gap while maintaining excellent *** show that the co-doped Sb and Sc act cooperatively to give a significant band bowing leading to a small band gap of~1.76 eV and a large polarization parameter~0.87 C/m^(2),in the quaternary Al_(1-x)Sc_(x)Sb_(y)N_(1-y)*** Sb impurity states become more continuous as a result of interactions with Sc and can be used for impurity-mediated *** on the landau-Khalatnikov model,the landau parameters and the corresponding ferroelectric hysteresis loops are obtained for the quaternary *** findings indicate that Al_(1-x)Sc_(x)Sb_(y)N_(1-y)is an excellent candidate as the channel material of FeSFET.

关键词： ferroelectricity Al_(1-x)Sc_(x)N FeSFET