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Statistical estimations for Plasmodium vivax malaria in South Korea

Asian Pacific Journal of Tropical Medicine 2015年第3期8卷 169-175页

作者： Youngsaeng Lee Hyeongap jang Jeong Ae Rhee Jeong-Soo park Department of Statistics Chonnam National University JW LEE Center for Global Medicine College of MedicineSeoul National University Department of Preventive Medicine Chonnam National University

Objective:To calculate the numbers of weekly infections and prevalence of malaria,and to predict future trend of malaria incidences in South ***:Weekly incidences of malaria for 13 years from the period 2001-2013 in South Korea were *** backcalculation equations were used with incubation period *** maximum likelihood estimation for Poisson model was also *** confidence intervals of the estimates were obtained by a bootstrap method.A regression model for time series of malaria incidences over13 years was fitted by the non-linear least squares method,and used to predict ***:The estimated infection curve is narrower and more concentrated in the summer than in the incidence *** started around the 19 th week and was over around the41 st *** maximum weekly infection 110 was obtained at the 29 th *** prevalence at the first week was around 496 persons,the minimum number was 366 at 22 nd week,and the maximum prevalence was 648 at 34 th *** drops in late spring with people that falling ill and had had long incubation periods and rose in the summer with new *** future forecast based on the regression model was that an increase at year 2014 compared to 2013 may reach a peak(at maximum about 70 weekly cases) at year *** a decreasing trend after ***:This work shows that back-calculation methods could work well in estimating the infection rates and the prevalence of *** obtained results can be useful in establishing an efficient preventive program for malaria *** method presented here can be used in other countries where incidence data and incubation period are available.

关键词： Back calculation Incidence Incubation period Infection Poisson model Prevalence Regression model

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An Enhanced Jacobi Precoder for Downlink Massive MIMO Systems

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Computers, Materials & Continua 2021年第7期68卷 137-148页

作者： park Chan-Yeob Hyun-Ro Jae Jun-Yong jang Song Hyoung-Kyu Department of Information and Communication Engineering and Convergence Engineering for Intelligent DroneSejong UniversitySeoul05006Korea

Linear precoding methods such as zero-forcing(ZF)are near optimal for downlink massive multi-user multiple input multiple output(MIMO)systems due to their asymptotic channel ***,as the number of users increases,the computational complexity of obtaining the inverse matrix of the gram matrix *** the computational complexity problem,this paper proposes an improved Jacobi(JC)-based precoder to improve error performance of the conventional JC in the downlink massive MIMO *** conventional JC was studied for solving the high computational complexity of the ZF algorithm and was able to achieve parallel ***,the conventional JC has poor error performance when the number of users increases,which means that the diagonal dominance component of the gram matrix is *** this paper,the preconditioning method is proposed to improve the error *** executing the JC,the condition number of the linear equation and spectrum radius of the iteration matrix are reduced by multiplying the preconditioning matrix of the linear *** further reduce the condition number of the linear equation,this paper proposes a polynomial expansion precondition matrix that supplements diagonal *** results show that the proposed method provides better performance than other iterative methods and has similar performance to the ZF.

关键词： Jacobi(JC) massive MIMO precondition polynomial expansion linear precoding

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Effect of citrulline on post-exercise rating of perceived exertion,muscle soreness,and blood lactate levels:A systematic review and meta-analysis

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Journal of Sport and Health Science 2020年第6期9卷 553-561页

作者： Hye Chang Rhim Sung Jong Kim Jewel park Ki-Mo jang College of Medicine Korea UniversitySeoul 02842Republic of Korea Department of Orthopaedic Surgery Anam HospitalKorea University College of MedicineSeoul 02841Republic of Korea

Background:Citrulline is one of the non-essential amino acids that is thought to improve exercise performance and reduce post-exercise muscle *** conducted a systematic review and meta-analysis to determine the effect of citrulline supplements on the post-exercise rating of perceived exertion(RPE),muscle soreness,and blood lactate ***:A random effects model was used to calculate the effect sizes due to the high variability in the study design and study populations of the articles included.A systematic search of PubMed,Web of Science,and *** was *** for study inclusion was limited to studies that were randomized controlled trials involving healthy individuals and that investigated the acute effect of citrulline supplements on RPE,muscle soreness,and blood lactate *** supplementation time frame was limited to 2 h before *** types and number of participants,types of exercise tests performed,supplementation protocols for L-citrulline or citrulline malate,and primary(RPE and muscle soreness)and secondary(blood lactate level)study outcomes were extracted from the identified ***:The analysis included 13 eligible articles including a total of 206 *** most frequent dosage used in the studies was 8 g of citrulline *** supplementation significantly reduced RPE(n=7,p=0.03)and muscle soreness 24-h and 48-h after post-exercise(n=7,p=0.04;n=6,p=0.25,respectively).However,citrulline supplementation did not significantly reduce muscle soreness 72-h post-exercise(n=4,p=0.62)or lower blood lactate levels(n=8,p=0.17).Conclusion:Citrulline supplements significantly reduced post-exercise RPE and muscle soreness without affecting blood lactate levels.

关键词： Amino acids Dietary supplements Ergogenic aid Nitric oxide Watermelon juice

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Oral administration of red ginseng powder fermented with probiotic alleviates the severity of dextran-sulfate sodium-induced colitis in a mouse model

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Chinese Journal of Natural Medicines 2017年第3期15卷 192-201页

作者： jang Sun-Hee park Jisang KIM Sae-Hae CHOI Kyung-Min KO Eun-Sil CHA Jeong-Dan LEE Young-Ran jang Hyonseok jang Yong-Suk Department of Molecular Biology and Institute for Molecular Biology and Genetics Chonbuk National UniversityJeonju 54896Korea Department of Bioactive Material Sciences and Research Center of Bioactive Materials Chonbuk National UniversityJeonju 54896Korea Department of Efficacy Research Institute of Jinan Red GinsengJinan 55442Korea Department of Mathematics Sogang UniversitySeoul 04107Korea Department of Oral Maxillofacial Surgery Korea University Ansan HospitalAnsan 15355Korea

Red ginseng is a well-known alternative medicine with anti-inflammatory *** exerts pharmacological effects through the transformation of saponin into metabolites by intestinal *** that intestinal microflora vary among individuals,the pharmacological effects of red ginseng likely vary among *** order to produce homogeneously effective red ginseng,we prepared probiotic-fermented red ginseng and evaluated its activity using a dextran sulfate sodium(DSS)-induced colitis model in *** analysis of intestinal damage indicated that the administration of probiotic-fermented red ginseng significantly decreased the severity of colitis,compared with the control and the activity was higher than that induced by oral administration of ginseng powder or probiotics *** analysis of the levels of serum IL-6 and TNF-α,inflammatory biomarkers that are increased at the initiation stage of colitis,were significantly decreased in probiotic-fermented red ginseng-treated groups in comparison to the control *** levels of inflammatory cytokines and mR NAs for inflammatory factors in colorectal tissues were also significantly decreased in probiotic-fermented red ginseng-treated ***,oral administration of probiotic-fermented red ginseng reduced the severity of colitis in a mouse model,suggesting that it can be used as a uniformly effective red ginseng product.

关键词： Colitis Fermentation Inflammation Probiotics Red ginseng

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Spontaneous resolution of gallbladder hematoma in blunt traumatic injury:A case report

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World Journal of Clinical Cases 2021年第28期9卷 8518-8523页

作者： Hyunseok jang Chang-Hwan park Yunchul park Euisung Jeong Naa Lee Jungchul Kim Younggoun Jo Division of Trauma Department of SurgeryChonnam National University Medical School and HospitalDong-gu 61469GwangjuSouth Korea Department of Internal Medicine Chonnam National University Medical School and HospitalDong-gu 61469GwangjuSouth Korea

BACKGROUND We report a case of intragallbladder hematoma and biliary tract obstruction caused by blunt gallbladder *** report that the patient was safely treated by conservative treatment after the obstruction was resolved by endoscopic retrograde cholangiopancreatography(ERCP).CASE SUMMARY A 67-year-old man was admitted via the emergency department due to complaints of right-sided abdominal pain that started 2 d *** days prior to presentation,the patient had slipped,fallen and struck his abdomen on a motorcycle *** initial vital signs were *** physical examination,he showed right upper quadrant pain and Murphy’s sign,with decreased bowel ***,he had had a poor appetite for 4 *** had been on aspirin for 2 years due to underlying *** simple radiography revealed a slight *** laboratory findings were as follows:white blood cell count,15.5×103/µL(normal range 4.8×10^(3)–10.8×10^(3));hemoglobin,9.4 g/dL;aspartate aminotransferase/alanine transferase,423/348 U/L;total bilirubin/direct bilirubin,4.45/3.26 mg/dL;-GTP,639 U/L(normal range 5–61 U/L);and C-reactive protein,12.32 mg/dL(0–0.3).Abdominal computed tomography showed a distended gallbladder with edematous wall change and a 55 mm×40 mm *** was observed in both the intrahepatic and common bile duct *** treatment was initiated,and ERCP was performed,with hemobilia found during *** cannulation,the patient’s symptoms were relieved,and after conservative management,the patient was discharged with no further *** 1-month follow-up,the gallbladder hematoma was completely *** In the case of traumatic injury to the gallbladder,conservative treatment is feasible even in the presence of hematoma.

关键词： Gallbladder Trauma Abdomnial injuries,Blunt injuries Cholecystitis Gallstone Case report

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Bilateral musculocutaneous neuropathy:A case report

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World Journal of Clinical Cases 2021年第5期9卷 1237-1246页

作者： Ji Won Jung Yu Chan park Jae Young Lee Jae Hyeon park Seong Ho jang Department of Rehabilitation Medicine Hanyang University HospitalSeoul 04763South Korea Department of Rehabilitation Medicine Hanyang University Guri HospitalGuri 11923South Korea

BACKGROUND Isolated musculocutaneous nerve injury is a rare ***,we report the first case of bilateral musculocutaneous neuropathy after vigorous stretching of both upper extremities with normal results of sensory nerve action *** should be aware of this rare condition that can appear *** addition,the interpretation of the aberrant electrodiagnostic study results of this case was *** SUMMARY A 29-year-old male complaining of bilateral forearm tingling and upper extremity weakness visited the outpatient *** symptoms began 6 mo prior,and he visited another hospital before visiting our *** diagnosis was not made even after cervical spine magnetic resonance imaging,electrodiagnostic study,brain magnetic resonance imaging,and arteriography were *** patient performed unique exercises that stretched the pectoralis minor and coracobrachialis *** the follow-up electrodiagnostic study,abnormal spontaneous activities in the bilateral biceps and brachialis muscles were *** patient was diagnosed with bilateral musculocutaneous *** pulse therapy was administered for approximately 6 *** treatment,his muscle strength returned to the predisease *** Clinicians should be aware of this condition,have adequate understanding of anatomy,and advise to correct inappropriate exercises.

关键词： Musculocutaneous nerve Peripheral neuropathy Electrodiagnosis Exercise Diagnosis Case report

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Improving ionic conductivity of von-Alpen-type NASICON ceramic electrolytes via magnesium doping

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Journal of Advanced Ceramics 2023年第5期12卷 1058-1066页

作者： Il-Seop jang Wooseok Go Bo-Ye Song Hayoung park Yun Chan Kang Jinyoung Chun Emerging Materials R&D Division Korea Institute of Ceramic Engineering and Technology(KICET)Jinju 52851Republic of Korea Department of Materials Science and Engineering Korea UniversitySeoul 02841Republic of Korea Energy Storage and Distribution Resources Division Lawrence Berkeley National LaboratoryBerkeley 94720USA

NASICON (sodium (Na) superionic conductor) compounds have attracted considerable attention as promising solid electrolyte materials for advanced Na-based batteries. In this study, we investigated the improvement in ionic conductivities of von-Alpen-type NASICON (vA-NASICON) ceramic electrolytes by introducing a magnesium ion (Mg^(2+)) as a heterogeneous element. The optimal Mg-doped vA-NASICON exhibited a high ionic conductivity of 3.64×10^(−3) S·cm^(−1), which was almost 80% higher than that of un-doped vA-NASICON. The changes in physicochemical properties of the vA-NASICONs through the Mg introduction were systematically analyzed, and their effects on the ionic conductivities of the vA-NASICON were studied in detail. When the optimal ratio of Mg^(2+) was used in a synthetic process, the relative density (96.6%) and grain boundary ionic conductivity (σgb) were maximized, which improved the total ionic conductivity (σt) of the vA-NASICON. However, when Mg^(2+) was introduced in excess, the ionic conductivity decreased because of the formation of an undesired sodium magnesium phosphate (NaxMgyPO_(4)) secondary phase. The results of this study are expected to be effectively applied in the development of advanced sodium-based solid electrolytes with high ionic conductivities.

关键词： NASICON solid electrolyte von-Alpen-type magnesium(Mg)doping ionic conductivity

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Chemical modification of ordered/disordered carbon nanostructures for metal hosts and electrocatalysts of lithium-air batteries

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InfoMat 2022年第1期4卷 105-129页

作者： Jeongyeon Lee Tae Hyung Lee Ho Won jang Ho Seok park School of Chemical Engineering Convergence Research Center for Energy and Environmental SciencesDepartment of Health Sciences and TechnologySamsung Advanced Institute for Health Sciences and Technology(SAIHST)Sungkyunkwan University(SKKU)SuwonRepublic of Korea Institute of Textiles Clothing The Hong Kong Polytechnic UniversityHung HomHong Kong SARChina Department of Materials Science and Engineering Research Institute of Advanced MaterialsSeoul National UniversitySeoulRepublic of Korea

Although lithium-air batteries(LABs)are considered the promising alternative of existing lithium–ion batteries owing to their high energy density of 11680 W h kg^(-1),their practical applications are limited by the technical issues,such as unstable solid electrolyte interface and dendrite formation from metal anode and insufficient bifunctional activities and durability from cathode *** order to resolve these bottlenecks,carbon nanostructures have been investigated owing to their high surface area,excellent electrical conductivity,electrochemical stability,and various modification ***,we comprehensively review a recent progress on the design of carbon nanostructures for their applications into metal hosts,protection layers,and bifunctional electrocatalysts of *** correlation between the crystalline,electronic,porous,and chemical structures and the electrochemical properties of carbon nanomaterials are discussed depending on their classification and *** chemical modifications,such as morphological control,hierarchical architecturing,heteroatom incorporation,and the formation of composites,for the improved electrochemical performances of anode and cathode will be also ***,we deal with the perspectives for the ongoing obstruction and future guidance.

关键词： bifunctional catalysts carbon nanostructures lithium-air batteries metal anodes surface modification

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Muscovite nanoparticles mitigate neuropathic pain by modulating the inflammatory response and neuroglial activation in the spinal cord

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Neural Regeneration Research 2020年第11期15卷 2162-2168页

作者： Ju-Young Oh Tae-Yeon Hwang Jae-Hwan jang Ji-Yeun park Yeonhee Ryu HyeJung Lee Hi-Joon park Acupuncture and Meridian Science Research Center Kyung Hee University26 Kyungheedae-roDongdaemun-guSeoulRepublic of Korea Department of Korean Medical Science Graduate School of Korean MedicineKyung Hee UniversitySeoulRepublic of Korea BK21 PLUS Korean Medicine Science Center College of Korean MedicineKyung Hee UniversitySeoulRepublic of Korea College of Korean Medicine Daejeon UniversityDaejeonRepublic of Korea Korean Institute of Oriental Medicine DaejeonRepublic of Korea

Despite numerous efforts to overcome neuropathic pain,various pharmacological drugs often fail to meet the needs and have many side *** is an aluminosilicate mineral that has been reported to have an anti-inflammatory effect,but the efficacy of muscovite for neuropathic pain has not been ***,we assessed whether muscovite nanoparticles can reduce the symptoms of pain by controlling the inflammatory process observed in neuropathic *** analgesic effects of muscovite nanoparticles were explored using partial sciatic nerve ligation model of neuropathic pain,in which one-third to onehalf of the nerve trifurcation of the sciatic nerve was tightly tied to the dorsal *** nanoparticles(4 mg/100μL)was given intramuscularly to evaluate its effects on neuropathic pain(3 days per week for 4 weeks).The results showed that the muscovite nanoparticle injections significantly alleviated partial sciatic nerve ligation-induced mechanical and cold *** the spinal cord,the muscovite nanoparticle injections exhibited inhibitory effects on astrocyte and microglia activation and reduced the expression of pro-inflammatory cytokines,such as interleukin-1β,tumor necrosis factor-α,interleiukin-6 and monocyte chemoattractant protein-1,which were upregulated in the partial sciatic nerve ligation ***,the muscovite nanoparticle injections resulted in a decrease in activating transcription factor 3,a neuronal injury marker,in the sciatic *** results suggest that the analgesic effects of muscovite nanoparticle on partial sciatic nerve ligation-induced neuropathic pain may result from inhibiting activation of astrocytes and microglia as well as pro-inflammatory *** propose that muscovite nanoparticle is a potential anti-nociceptive candidate for neuropathic *** experimental protocols in this study were approved by the Institutional Animal Ethics Committee(IACUC)at Dongguk University,South Korea(approval No.2017-022-1)

关键词： astrocyte microglia muscovite nanoparticle neuropathic pain partial sciatic nerve ligation pharmacopuncture pro-inflammatory cytokine spinal cord

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An insert in the Hpy region of hscp in Hefiothis virescens （Lepidoptera： Noctuidae） reveals a possible CORE-SINE of insects

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Insect Science 2009年第3期16卷 219-226页

作者： Sujin park Thomas M. Brown Sam-Kyu Kim Chunkeun Lim jang Hyun Hur Yong Chul park Saeyoull Cho Life Science Institute University of Michigan Ann Arbor M148109 USA Genectar Corn LLC 539 Kafispell Ave. Whitefish MT 59937-2743 USA Division of Biological Environment College of Agriculture and Life Science Kangwon National University Chuncheon 200-701Korea Department of Appfied Biology Division of Bio-resource of Technology College of Agriculture and Life Science Kangwon National University Chuncheon 200-701 Korea Department of Plant Biotechnology Program Division of Biotechnology School of BiotechnologyInstitute of Bioscience and Biotechnology Kangwon National University Chuncheon 200-701 Korea

A new putative transposon was identified in the tobacco budworm, Helio- this virescens. This transposon was characterized as a full length CORE-SINE （65 bp of ＂CORE＂ core specific nucleotide short interspersed elements） that resembled sequences from three other lepidopterans and humans. In particular, the A-box and B-box regions of this sequence most closely conformed to the signature of CORE-SINEs from widely divergent species. This CORE-SINE was present as a polymorphism in a hypervariable region of the gene hscp, which is the target of pyrethroid insecticides and other xenobiotics in the nerve axon. We described this new putative transposon as Noct-1 due to its presence in a noctuid moth. This is the first description of a full-length CORE-SINE with the A-box, B-box, target site duplication, and candidate core domain from an insect.

关键词： A-box B-box CORE-SINE Heliothis virescens Noct-1 target site duplication

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