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Improved specimen adequacy using jumbo biopsy forceps in patients with Barrett's esophagus

World Journal of Gastroenterology 2015年第17期21卷 5328-5335页

作者： Jan Martinek jana Maluskova Magdalena Stefanova Inna Tuckova Stepan Suchanek Zuzana Vackova jana krajciova Marek Kollar Miroslav Zavoral Julius Spicak Department of Hepatogastroenterology Institute for Clinical and Experimental Medicine14021 PragueCzech Republic Faculty of Medicine University of Ostrava70103 OstravaCzech Republic Department of Pathology IKEM14021 PragueCzech Republic Department of Internal Medicine Hospital "Na Frantisku"11000 PragueCzech Republic Department of Pathology Central Military Hospital16902 PragueCzech Republic Department of Medicine Charles UniversityMilitary University Hospital16902 PragueCzech Republic

AIM:To assess the sampling quality of four different forceps(three large capacity and one jumbo) in patients with Barrett's ***:This was a prospective,single-blind study.A total of 37 patients with Barrett's esophagus were *** or random biopsies with all four forceps were obtained from each patient using a diagnostic endoscope during a single *** following forceps were tested:A:FB-220 K disposable large capacity;B:BI01-D3-23 reusable large capacity;C:GBF-02-23-180 disposable large capacity;and jumbo:disposable Radial Jaw 4 *** primary outcome measurement was specimen adequacy,defined as a well-oriented biopsy sample 2 mm or greater with the presence of muscularis ***:A total of 436 biopsy samples were *** found a significantly higher proportion of adequate biopsy samples with jumbo forceps(71%)(P < 0.001 vs forceps A:26%,forceps B:17%,and forceps C:18%).Biopsies with jumbo forceps had the largest diameter(median 2.4 mm)(P < 0.001 vs forceps A:2 mm,forceps B:1.6 mm,and forceps C:2mm).There was a trend for higher diagnostic yield per biopsy with jumbo forceps(forceps A:0.20,forceps B:0.22,forceps C:0.27,and jumbo:0.28).No complications related to specimen sampling were observed with any of the four tested ***:Jumbo biopsy forceps,when used with a diagnostic endoscope,provide more adequate specimens as compared to large-capacity forceps in patients with Barrett's esophagus.

关键词： Barrett's esophagus Barrett's esophagusrelatedneoplasia Biopsy forceps Jumbo forceps Specimen adequacy

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