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Distinct MLT asymmetry of auroral kilometric radiation observed by the FAST satellite

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Earth and Planetary Physics 2025年第1期9卷 188-193页

作者： JiaWen Tang Sai Zhang FuLiang Xiao HongMing Yang Si Liu YiHua He Chang Yang YuYue Jin ZhouKun Deng Ping Li Archie james Johnston School of Physics and Electronic Sciences Changsha University of Science and TechnologyChangsha 410114China Hunan Province Higher Education Key Laboratory of Modeling and Monitoring on the Near-Earth Electromagnetic Environments Changsha University of Science and TechnologyChangsha 410114China School of Electrical and Information Engineering Changsha University of Science and TechnologyChangsha 410114China

Auroral Kilometric Radiation(AKR)is a common radio emission,which can contribute to the magnetosphere−ionosphere−atmosphere *** emissions have been observed in all magnetic planet magnetospheres of the solar *** this study,using observations from the FAST satellite from 30 August 1996 to 9 September 2001,the distribution of AKR in altitude=500−4500 km and invariant latitude(|ILAT|)=60°−80°has been analyzed.63045 AKR samples have been identified with~48%(52%)samples on the dayside(nightside).Of considerable interest,there is a distinct MLT asymmetry with the high occurrence rate in MLT=05−08 and 18−22(02−05 and 12−17)in the northern(southern)*** distinct MLT asymmetry is associated with the direction of Bxof the interplanetary magnetic *** addition,the occurrence rate on the nightside clearly increases as the index *** study further enriches *** and understanding of AKR in the magnetosphere as well as other similar radio emissions.

关键词： asymmetry auroral kilometric radiation interplanetary magnetic field

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避世之所加拿大亚瑟住宅

室内设计与装修 2025年第1期 46-49页

作者：无 james Brittain(摄影) coco(编译) 5468796 Architecture 不详

亚瑟住宅是为一对来自南非的夫妇设计的,他们一位是热衷园艺的木匠,另一位是急诊室医生。夫妇俩一直在寻找一个适中的“避难所”,与外界隔绝,并且有足够的空间来保护隐私。住宅所在的小区是一个成熟社区,原有的小平房正迅速被传统住宅... 详细信息

亚瑟住宅是为一对来自南非的夫妇设计的,他们一位是热衷园艺的木匠,另一位是急诊室医生。夫妇俩一直在寻找一个适中的“避难所”,与外界隔绝,并且有足够的空间来保护隐私。住宅所在的小区是一个成熟社区,原有的小平房正迅速被传统住宅取代。与此相反,亚瑟夫妇希望用一种深思熟虑的替代方案来挑战这种发展模式。

关键词：传统住宅替代方案保护隐私避难所亚瑟园艺小区加拿大

Hepatitis B virus outreach to immigrant population in Greater Boston Area: Key to improving hepatitis B knowledge

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World Journal of Gastroenterology 2017年第42期23卷 7626-7634页

作者： Raissa Djoufack Scarlett Se Yun Cheon Aisha Mohamed Fatou Faye Korka Diouf Richard Colvin james Morrill Ann-Marie Duffy-keane Ponni Perumalswami Gonzague Jourdain Dahlene Fusco Universite des Montagnes Wellesley College Cooper Medical School of Rowan University Suffolk University Division of General Internal Medicine MGH MGH Community Health Associates Icahn School of Medicine at Mount Sinai Institut de Recherche pour le Dé-veloppement Chiang Mai University Harvard T.H. Chan School of Public Health Division of Infectious Disease Department of Medicine Vaccine and Immunotherapy Center Laboratory of Systems Pharmacology Harvard Medical School

AIM To characterize the understanding of hepatitis B virus(HBV) and determine if outreach improves HBV understanding among Greater Boston Area immigrants. METHODS Six outreach sessions were held in various community venues in the Greater Boston Area. Verbal consent was obtained from participants prior to starting each session. Each session included a pre-session questionnaire, followed by a teaching session, and then a post-session questionnaire. In person interpreters were present for translation during the teaching session and assistance for questionnaire completion when needed. The questions were developed based on the HBV clinical experience of physicians who serve largely immigrant populations. Questionnaires included Likerttype scale, open-ended, and true-false questions. All results were anonymous. RESULTS One hundred and one people participated in this study. Participants were 30% male with ages ranging from 19 to 87 years. The study population included immigrants from 21 countries, as well as seven United States-born participants. The greatest numbers of participants were from Somalia(44%), Morocco(10%), and Cameroon(8%). Pre session questionnaires revealed that 42% of participants were unaware that HBV can cause cancer, and 50% were unaware that therapies for HBV exist. Our brief teaching intervention led to improved scores on post session questionnaires. For example, at baseline, 58% of participants responded correctly to the question "HBV infection can cause scarring of the liver and liver cancer", whereas 79% of participants responded correctly after the teaching session(P = 0.01). Furthermore, the mean of total correct answers in the true or false portion of the questionnaire increased from 5.5 to 7.6(P < 0.001).CONCLUSION A teaching session targeting Boston Immigrants atrisk for HBV helped improve scores on HBV knowledge questionnaires. Outreach may empower at-risk patients to pro-actively seek HBV care.

关键词： Hepatitis B virus Outreach Linkage to care Immigrant Boston

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina Hromada Patrick Heimel Markus Kerbl LászlóGál Sylvia Nürnberger Barbara Schaedl james Ferguson Nicole Swiadek Xavier Monforte Johannes C.Heinzel Antal Nógrádi Andreas H.Teuschl-Woller David Hercher Department Life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria Ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNGCs). However, the use of tNGCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNGCs and compared the various features of these improved silk^(+) tNGCs with the tubes without holes(silk^(–) tNGCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNGCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report

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Neural Regeneration Research 2025年第4期20卷 1207-1216页

作者： Pascal J.Goldschmidt-Clermont Aisha Khan George Jimsheleishvili Patricia Graham Adriana Brooks Risset Silvera Alexander J.P.Goldschmidt Damien D.Pearse W.Dalton Dietrich Allan D.Levi james D.Guest Miller School of Medicine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami Project to Cure Paralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzady International LLC MiamiFLUSA Neurological Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential for the maintenance and function of motor neurons,axonal networks,and the neuromuscular *** amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann cell function may also be ***,important signaling and potential trophic activities of Schwann cell-derived exosomal vesicles have been *** case report describes the treatment of a patient with advanced amyotrophic lateral sclerosis using serial intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles,marking,to our knowledge,the first instance of such *** 81-year-old male patient presented with a 1.5-year history of rapidly progressive amyotrophic lateral *** initial diagnosis,the patient underwent a combination of generic riluzole,sodium phenylbutyrate for the treatment of amyotrophic lateral sclerosis,and *** patient volunteered to participate in an FDA-approved single-patient expanded access treatment and received weekly intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles to potentially restore impaired Schwann cell and motor neuron *** confirmed that cultured Schwann cells obtained from the amyotrophic lateral sclerosis patient via sural nerve biopsy appeared impaired(senescent)and that exposure of the patient’s Schwann cells to allogeneic Schwann cell-derived exosomal vesicles,cultured expanded from a cadaver donor improved their growth capacity in *** a period of observation lasting 10 weeks,during which amyotrophic lateral sclerosis Functional Rating Scale-Revised and pulmonary function were regularly monitored,the patient received weekly consecutive infusions of 1.54×1012(×2),and then consecutive infusions of 7.5×1012(×6)allogeneic Schwann cell-derived exosomal vesicles diluted in 40 mL of Dulbecco’s phosphate-buffered *** of the infusions were associated with adverse events such as infusion reactions(allergic or otherwise)or

关键词： allogeneic amyotrophic lateral sclerosis exosomes infusion neuromuscular junction Schwann cell

STUDIES OF THE ANTENNA EFFECT IN POLYMER MOLECULES ENERGY MIGRATION AND TRAPPING IN NAPHTHALENE-CONTAINING POLYELECTROLYTES

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Chinese Journal of Polymer Science 1998年第3期16卷 261-267页

作者： GUILLET james Department of Chemistry University of Toronto Toronto M5S 3H6 Canada

Polymers of 1- and 2-vinylnaphthalene containing more than about 50 mol% sulfonic acid groups dissolve in water to form 'hypercoiled' conformations which have many of the properties of micelles. Hydrophobic molecules such as anthracene and perylene are selectively absorbed in these pseudo micellar structures, and their fluorescence emission is sensitized by energy transfer from the surrounding naphthalene chromophores. When irradiated with UV light in the presence of oxygen, the emission of perylene rapidly decreases. It is proposed that this is due to reaction of singlet oxygen with the perylene trapped in the hypercoiled polymer. (Author abstract) 3 Refs.

关键词： Sulfonated vinyl naphthalene polymers Transport of excitation energy Anthracene Perylene Tripping

Alternative views of biological species: reproductively isolated units or genotypic clusters?

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National Science Review 2020年第8期7卷 1401-1407页

作者： james Mallet Department of Organismic and Evolutionary Biology Harvard University

Wang et al. in this journal argue that it may be time to abandon a classic idea about species, the biological species concept(BSC), given recent findings with genomic data on closely related taxa [1]. Furthermore, they propose a set of tests on genetic or genomic data that might lead to acceptance or rejection of the biological species concept.

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Sugarcane press mud modification of expansive soil stabilized at optimum lime content:Strength,mineralogy and microstructural investigation

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Journal of Rock Mechanics and Geotechnical Engineering 2020年第2期12卷 395-402页

作者： Jijo james SSN College of Engineering Chennai603110India

This study attempted to investigate the potential of sugarcane press mud(PM) as a secondary additive in conjunction with lime for the stabilization of an expansive *** physico-mechanical properties of an expansive soil,such as plasticity,shrink-swell behavior,unconfined compressive strength(UCS),mineralogical and microstructural characteristics were *** expansive soil was stabilized at its optimum lime content(7%) for producing maximum strength,and was modified with four different quantities of PM in small dosages(0.25%-2%).Cylindrical soil samples,38 mm in diameter and 76 mm in height,were cast and cured for varying periods to evaluate the strength of the amended *** spent samples after strength tests were further used for determination of other *** test results revealed that PM modification led to a substantial improvement in 7-d strength and noticeable increase in 28-d strength of the lime-stabilized soil(LSS).The addition of PM does not cause any detrimental changes to the shrink-swell properties as well as plasticity nature of the stabilized soil,despite being a material of organic *** investigation revealed that the formation of calcium silicate hydrate(CSH) minerals,similar to that of pure lime stabilization with only the type of mineral varying due to the modification of PM addition,does not significantly alter the microstructure of the LSS except for superficial changes being noticed.

关键词： Expansive soil Lime stabilization Press mud(PM) Strength Shrink-swell Mineralogy Microstructure

Wing, tail, and vocal contributions to the complex acoustic signals of courting Calliope hummingbirds

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Current Zoology 2011年第2期57卷 187-196页

作者： Christopher james CLARK Peabody Museum of Natural History Yale University PO Box 208106 New Haven CT 06511 USA Museum of Vertebrate Zoology University of California- Berkeley Berkeley CA USA

Multi-component signals contain multiple signal parts expressed in the same physical modality. One way to identify individual components is if they are produced by different physical mechanisms. Here, I studied the mechanisms generating acoustic signals in the courtship displays of the Calliope hummingbird Stellula calliope. Display dives consisted of three synchronized sound elements, a high-frequency tone （hfl）, a low frequency tone （lft）, and atonal sound pulses （asp）, which were then followed by a frequency-modulated fall. Manipulating any of the rectrices （tail-feathers） of wild males impaired production of the lft and asp but not the hfl or fall, which are apparently vocal. I tested the sound production capabilities of the rectrices in a wind tunnel. Single rectrices could generate the lft but not the asp, whereas multiple rectrices tested together produced sounds sitlfilar to the asp when they fluttered and collided with their neighbors percussively, representing a previously unknown mechanism of sound production. During the shuttle display, a trill is generated by the wings during pulses in which the wingbeat frequency is elevated to 95 Hz, 40% higher than the typical hovering wingbeat frequency. The Calliope hummingbird courtship displays include sounds produced by three independent mechanisms, and thus include a minimum of three acoustic signal components. These acoustic mechanisms have different constraints and thus potentially contain different messages. Producing multiple acoustic signals via multiple mechanisms may be a way to escape the constraints present in any single mechanism .

关键词： Calliope Hummingbird Courtship Multicomponent Signal Sonation Wind Tunnel