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Radiofrequency ablation versus microwave ablation for colorectal liver metastases:long-term results of a retrospective cohort surgical experience

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Hepatobiliary Surgery and Nutrition 2024年第5期13卷 759-770,I0001页

作者： Ali Gunduz Sarioglu Chase J.Wehrle Ege Akgun Arturan Ibrahimli james f.Bena Eren Berber Department of Endocrine Surgery Cleveland ClinicClevelandOHUSA Department of General Surgery Cleveland ClinicClevelandOHUSA Department of Quantitative Health Sciences Cleveland ClinicClevelandOHUSA

Background:Ablation is an alternative treatment modality for selected patients with colorectal liver metastases(CRLMs).Although initially widely performed via radiofrequency ablation(RfA),more recently,microwave ablation(MWA)is being preferred due to its perceived superiority in creating the ablation *** aim of this study is to compare the long-term efficacy of these two modalities performed ***:Patients undergoing surgical liver ablation from 2005-2023 at a tertiary center by a single surgeon for CRLM were included in a retrospective institutional review board-approved *** were compared using Wilcoxon,Chi-square,Kaplan-Meier,and Cox multivariate regression *** data are presented as median(interquartile range).Results:There were a total of 242 *** RfA was done in 121 patients with 303 lesions and laparoscopic MWA in 121 patients with 300 *** was no difference between the groups regarding operative time(161 vs.147 minutes,respectively,P=0.4),perioperative morbidity(3%vs.8%,respectively,P=0.2)or hospital stay(1 vs.1 day,P=0.05).Local recurrence(LR)per lesion with at least 1 year of imaging follow-up was 29%in the RfA and 13%in the MWA group(Pf *** control these variables,direct matching was *** cohort included 189 ***-Meier analysis of these cohorts showed increased LR-free survival in the MWA group *** RfA group(P=0.005).Conclusions:This large study confirms our initial observation that local tumor control rate is better after MWA ***.

关键词： Colorectal cancer liver metastasis liver ablation radiofrequency ablation(RfA) microwave ablation(MWA) local recurrence(LR)

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The Importance of Posterior Tibial Slope in TKR: Pre and Post-Operative Measurements in United States Osteoarthritic Patients

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Open Journal of Orthopedics 2024年第8期14卷 374-379页

作者： frederick f. Buechel Sr frederick f. Buechel jr Rutgers New Jersey Medical School Department of Orthopaedic Surgery Newark USA Lenox Hill Hospital Department of Orthopaedic Surgery New York USA

Background: Sagittal plane placement of the tibial component in total knee replacement (TKR) has important implications for maximizing the range of flexion motion, allowing collateral ligaments to function more normally, as well as providing ideal compressive loading on the tibial bone-prosthesis interface. This study attempts to quantify the normal posterior tibial slope (PTS) angle pre-operatively and post-operatively in osteoarthritic patients after using a conventional extramedullary tibial resection guide to assess its effectiveness. Methods: forty-nine primary cementless total knee replacements in 34 osteoarthritic patients were measured radiographically pre-operatively and one year post-operatively to determine the PTS and its effect on range of motion. Lateral X-rays, using the anterior cortical line of the tibia, were employed for all measurements. Results: Pre-operative PTS measured 11.83˚ (range 5˚ - 18˚), while post-operative PTS of implanted tibial components measured 11.30o (range 4˚ - 18˚). The pre-operative range of motion of 112˚ (range 30˚ to 135˚) was improved to 119˚ (range 90˚ to 135˚) post-operatively after 1 year. Conclusions: Anterior tibial shaft referencing using a conventional extramedullary tibial resection guide provides an easy and convenient method for reproducing the anatomical PTS during TKR. This methodology provided improvement in average range of motion from 112˚ pre-operatively to 119˚ post-operatively at one year.

关键词： Posterior Tibial Slope Posterior Tibial Inclination Extramedullary Tibial Resection Guide Total Knee Alignment

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Phylogeny and taxonomy of Ophiognomonia(Gnomoniaceae,Diaporthales),including twenty-five new species in this highly diverse genus

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fungal Diversity 2012年第6期57卷 84-146页

作者： Donald M.Walker Lisa A.Castlebury Amy Y.Rossman Luis C.Mejía james f.white Department of Natural Sciences The University of FindlayFindlayOH 45840USA Systematic Mycology&Microbiology Laboratory USDA Agricultural Research ServiceBeltsvilleMD 20705USA Smithsonian Tropical Research Institute Apartado0843-03092BalboaAnconRepublic of Panama Department of Plant Biology and Pathology Rutgers UniversityNew BrunswickNJ 08901USA

Species of Ophiognomonia are leaf-inhabiting endophytes,pathogens,and saprobes that infect plants in the families Betulaceae,fagaceae,Juglandaceae,Lauraceae,Malvaceae,Platanaceae,Rosaceae,Salicaceae,and *** on extensive collecting,this speciesrich genus is now known to have a world wide distribution in primarily temperate areas,although some species are known from the *** of DNA sequences from three markers including guanine nucleotide-binding protein subunit beta-like protein(MS204),translation elongation factor 1α(tef-1α),and the ITS region including ITS1,5.8 S rDNA and ITS2 regions(ITS)were used to define phylogenetic species in *** plant association correlated with these ***-five new species of Ophiognomonia and two new combinations are proposed with descriptions and *** addition,descriptions and illustrations are provided for 12 other species of Ophiognomonia.A key is provided to the 45 currently accepted species of *** disposition of additional names in Ophiognomonia is also discussed.

关键词： Birch foliar pathogen Butternut canker GCPSR Genealogical sorting index Host associations MS204 Multilocus phylogeny Walnut anthracnose and leaf blotch

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理解老年人的身体活动:基于时空行为视角的研究

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体育科学 2024年第1期44卷 78-87页

作者：成佳俐仇军 james f.Sallis 于洪军河北师范大学公共体育教学部河北石家庄050024 湖州师范学院体育与大健康研究院浙江湖州313000 美国加州大学圣地亚哥分校家庭医学与公共卫生系加利福尼亚圣地亚哥92093 清华大学体育部北京100084

目的:从时空行为视角对建成环境与老年人户外身体活动的时空行为特征进行研究,为促进我国老年人身体活动水平提升和应对老龄化趋势提供新思路。方法:采用全球定位系统(global position system,GPS)和三维加速度计对126名老年人时空行为... 详细信息

目的:从时空行为视角对建成环境与老年人户外身体活动的时空行为特征进行研究,为促进我国老年人身体活动水平提升和应对老龄化趋势提供新思路。方法:采用全球定位系统(global position system,GPS)和三维加速度计对126名老年人时空行为数据进行同步收集,通过空间算法将环境暴露数据与身体活动数据相关联,总结其出行方式、出行时间、出行频率、出行范围等特征。结果:1)老年人户外身体活动存在“点-线”型、“候鸟”型、“条链”型、“自由”型、“邻里”型、“综合”型6种时空模式;2)老年人主要户外身体活动范围为家附近500 m左右;3)老年人近45%的热量消耗和中高强度身体活动发生在户外空间,主要户外活动兴趣点为休闲娱乐、购物和运动健身;4)老年人户外身体活动特征以出行频率高和短时耗为主,出行次数对身体活动水平有显著影响,出行次数每增加1次,平均每周户外身体活动水平增加20.5 min。结论:我国老年人户外身体活动呈现出多样化的时空行为模式,未来可以将增加出行次数作为促进老年人身体活动水平的切入点。

关键词：时空行为建成环境老年人户外身体活动

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What diameter?What height?Influence of measures of average tree size on area-based allometric volume relationships

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forest Ecosystems 2024年第1期11卷 100-109页

作者： Yilin Wang John A.Kershaw Mark J.Ducey Yuan Sun james B.McCarter Integrated forest Mensuration and Systems Analysis Laboratory Faculty of Forestry and Environmental ManagementUniversity of New BrunswickFrederictonNBCanada Department of Natural Resources and the Environment University of New HampshireDurhamNHUSA College of forestry Nanjing Forestry UniversityNanjing210037China Scientific Programmer RayonierYuleeFLUSA

Volume is an important attribute used in many forest management *** from 83 fixed-area plots located in central New Brunswick,Canada,are used to examine how different measures of stand-level diameter and height influence volume prediction using a stand-level variant of Honer's(1967)volume *** density was included in the models(Volume=f(Diameter,Height,Density))choice of diameter measure was more important than choice of height *** density was not included(Volume=f(Diameter,Height)),the opposite was *** models with density included,moment-based estimators of stand diameter and height performed better than all other *** models without density,largest tree estimators of stand diameter and height performed better than other *** overall best equation used quadratic mean diameter,Lorey's height,and density(root mean square error=5.26 m^3·ha^(-1);1.9%relative error).The best equation without density used mean diameter of the largest trees needed to calculate a stand density index of 400 and the mean height of the tallest 400 trees per ha(root mean square error=32.08 m^(3)·ha^(-1);11.8%relative error).The results of this study have some important implications for height subsampling and LiDAR-derived forest inventory analyses.

关键词： Allometric relationships Stand structure Volume estimation Stand-level attributes

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Comparing four machine learning algorithms for household non-intrusive load monitoring

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Energy and AI 2024年第3期17卷 206-219页

作者： Thomas Lee Young james Gopsill Maria Valero Sindre Eikevåg Ben Hicks University of Bristol UK

The combination of Machine Learning (ML), smart energy meters, and availability of household appliance energy profile data has opened new opportunities for Non-Intrusive Load Monitoring (NILM). However, the number of options makes it challenging in selecting optimal combinations for different energy applications, which requires studies to examine their *** paper contributes one such study that investigated four established ML approaches – K Nearest Neighbour (KNN), Support Vector Machine (SVM), eXtreme Gradient Boosting (XGBoost) and Convolutional Neural Network (CNN) – and their performance in classifying appliance events from Alternating Current (AC) and Root Mean Square (RMS) energy data where the sampling frequency and training dataset set size was varied (10 Hz–1 kHz and 50–2000 examples per class, respectively). The computational expense during training, testing and storage was also assessed and evaluated with reference to real-world *** CNN classifier trained on AC data at 500 Hz and 11,000 examples gave the best f1-score (0.989) followed by the KNN classifier (0.940). The storage size required by the CNN models was 3̃MB, which is very close to fitting on cost-effective embedded system microcontrollers. This would prevent high-rate data needing to be sent to the cloud as analysis could be performed on edge computing Internet-of-Things (IoT) devices.

关键词： NILM ML Edge computing Signal processing Smart meters

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Localized-states quantum confinement induced by roughness in CdMnTe/CdTe heterostructures grown on Si(111) substrates

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Journal of Semiconductors 2024年第9期 34-42页

作者： Leonarde do Nascimento Rodrigues Wesley fiorio lnoch Marcos L.f.Gomes Odilon D.D.Couto jr. Bráulio S.Archanjo Sukarno Olavo ferreira Physics Department Federal University of Vi?osa Instituto de física Gleb Wataghin Universidade Estadual de Campinas National Institute of Metrology Quality and Technology (Inmetro) Materials Metrology Division (DIMAT)

This work shows that despite a lattice mismatch of almost 20%, CdMnTe/CdTe/CdMnTe heterostructures grown directly on Si(111) have surprisingly good optical emission properties. The investigated structures were grown by molecular beam epitaxy and characterized by scanning transmission electron microscopy, macro-and micro-photoluminescence. Low temperature macro-photoluminescence experiments indicate three emission bands which depend on the CdTe layer thickness and have different confinement characteristics. Temperature measurements reveal that the lower energy emission band (at 1.48 eV)is associated to defects and bound exciton states, while the main emission at 1.61 eV has a weak 2D character and the higher energy one at 1.71 eV has a well-defined (zero-dimensional, 0D) 0D nature. Micro-photoluminescence measurements show the existence of sharp and strongly circularly polarized (up to 40%) emission lines which can be related to the presence of Mn in the heterostructure. This result opens the possibility of producing photon sources with the typical spin control of the diluted magnetic semiconductors using the low-cost silicon technology.

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Storylines of family medicine Ⅹ:standing up for diversity,equity and inclusion

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family Medicine and Community Health 2024年第S3期12卷 89-98页

作者： William B Ventres Leslie A Stone Wayne W Bryant jr Mario f Pacheco Edgar figueroa francis N Chu Shailendra Prasad David N Blane Na'amah Razon Ranit Mishori Robert L ferrer Garrett S Kneese family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA family and Community Medicine University of New Mexico School of MedicineAlbuquerqueNew MexicoUSA Medicine Weill Cornell Medical CollegeNew YorkNew YorkUSA San Jose family Medicine Residency Kaiser PermanenteSan JoseCaliforniaUSA family Medicine and Community Health University of Minnesota Medical School—Twin Cities CampusMinneapolisMinnesotaUSA School of Health and Wellbeing University of GlasgowGlasgowUK family and Community Medicine University of CaliforniaDavisSacramentoCaliforniaUSA family Medicine Georgetown University School of MedicineWashingtonDistrict of ColumbiaUSA family and Community Medicine UT Health San Antonio Long School of MedicineSan AntonioTexasUSA UC San Diego family Medicine Residency Program San DiegoCaliforniaUSA

Storylines of family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅹ:standing up for diversity,equity and inclusion’,authors address the following themes:‘The power of diversity—why inclusivity is essential to equity in healthcare’,‘Medical education for whom?’,‘Growing a diverse and inclusive workforce’,‘Therapeutic judo—an inclusive approach to patient care’,‘Global family medicine—seeing the world“upside down”’,‘The inverse care law‘,‘Social determinants of health as a lens for care’,‘Why family physicians should care about human rights’and‘Toward health equity—the opportunome’.May the essays that follow inspire readers to promote change.

关键词： illustration education family

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Methionine sources and genotype affect embryonic intestinal development, antioxidants, tight junctions, and growth-related gene expression in chickens

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Animal Nutrition 2024年第1期16卷 218-230页

作者： james K.Lugata Sawadi f.Ndunguru Gebrehaweria K.Reda Xénia E.Ozsváth Eszter Angyal Levente Czeglédi Gabriella Gulyás Renáta Knop János Oláh Zoltán Mészár Rita Varga Brigitta Csernus Csaba Szabó Department of Animal Nutrition and Physiology Faculty of Agriculture and Food Sciences and Environmental Management University of Debrecen faculty of Agriculture and food Sciences and Environmental Management Doctoral School of Animal Science University of Debrecen Department of Animal Husbandry Faculty of Agriculture and Food Sciences and Environmental Management University of Debrecen Department of Evolutionary Zoology and Human Biology Faculty of Science and Technology University of Debrecen Institutes for Agricultural Research and Educational farm University of Debrecen Department of Anatomy Histology and Embryology Faculty of Medicine University of Debrecen

Methionine(Met) is an essential and first limiting amino acid in the poultry diet that plays a significant role in chicken embryonic development and growth. The present study examined the effect of in ovo injection of DL-Met and L-Met sources and genotypes on chicken embryonic-intestinal development and health. fertilized eggs of the two genotypes, TETRA-SL layer hybrid(TSL)—commercial layer hybrid and Hungarian Partridge colored hen breed(HPC)—a native genotype, were randomly distributed into four treatments for each genotype. The treatment groups include the following: 1) control non-injected eggs(NoIn); 2) saline-injected(SaIn); 3) DL-Met injected(DLM); and 4) L-Met injected(LM). The in ovo injection was carried out on 17.5 d of embryonic development; after hatching, eight chicks per group were sacrificed, and the jejunum was extracted for analysis. The results showed that both DLM and LM groups had enhanced intestinal development as evidenced by increased villus width, villus height, and villus area(P ficantly reduced crypt depth, glutathione(GSH) content, glutathione S-transferase 3 alpha(GST3), occludin(OCLN) gene expression and increased villus height to crypt depth ratio in the TSL genotype than the LM group(P factor 1(IGf1) gene, tricellulin(MD2), occludin(OCLN),superoxide dismutase 1(SOD1), and GST3 genes than the TSL genotype(P findings showed that in ovo injection of Met enhanced intestinal development, and function, with genotypes responding differently under normal conditions. Genotypes also influenced the expression of intestinal antioxidants, tight junction, and growth-related genes.

关键词： DL-Methionine L-Methionine In ovo injection Intestinal development Poultry

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Molecular characterization of an outbreak-involved Bacillus anthracis strain confirms the spillover of anthrax from West Africa

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Infectious Diseases of Poverty 2024年第1期13卷 93-94页

作者： Shuchao Wang Roland Suluku Mohamed B.Jalloh Ahmed f.Samba Baogui Jiang Yubiao Xie Doris Harding Mengyao Zhang foday Sahr Mahmud E.Sesay james S.Squire Mohamed A.Vandi Moinina N.Kallon Shoufeng Zhang Rongliang Hu Yuee Zhao Zhiqiang Mi Changchun Veterinary Research Institute Chinese Academy of Agricultural Sciences Changchun China Department of Animal Sciences School of Agriculture and Food Sciences Njala University Njala Sierra Leone Department of Microbiology College of Medicine and Allied Health Sciences University of Sierra Leone Freetown Sierra Leone Ministry of Agriculture and food Sciences Freetown Sierra Leone Beijing Institute of Microbiology and Epidemiology Beijing China Ministry of Health and Sanitation Freetown Sierra Leone Beijing Institute of Biotechnology Beijing China

Background Anthrax,a zoonotic disease caused by the spore-forming bacterium Bacillus anthracis,remains a major global public health concern,especially in countries with limited *** Leone,a West African country historically plagued by anthrax,has almost been out of report on this disease in recent *** this study,we described a large-scale anthrax outbreak affecting both animals and humans and attempted to characterize the *** The causative agent of the animal outbreak in Port Loko District,Sierra Leone,between March and May 2022 was identified using the nanopore sequencing technique.A nationwide active surveillance was implemented from May 2022 to June 2023 to monitor the occurrence of anthrax-specific symptoms in *** cases were subsequently verified using quantitative polymerase chain ***-genome sequencing was accomplished by combining long-read and short-read sequencing *** phylogenetic analysis was performed based on the full-chromosome single nucleotide *** The outbreak in Port Loko District,Sierra Leone,led to the death of 233 animals between March 26th and May 16th,*** ruled out the initial suspicion of Anaplasma species and successfully identified *** as the causative agent of the *** a result of the government's prompt response,out of the 49 suspected human cases identifed during the one-year active surveillance,only 6 human cases tested positive,all within the frst month after the official declaration of the *** phylogenetic analysis indicated that the BaSL2022 isolate responsible for the outbreak was positioned in the ***.153 clade within the TransEuroAsian group of *** We successfully identifed a large-scale anthrax outbreak in Sierra *** causative isolate of ***,BaSL2022,phylogenetically bridged other lineages in ***.153 clade and neighboring genetic groups,***.144 and ***.148,

关键词： Molecular identification Anthrax Bacillus anthracis Sierra Leone Phylogeny Single nucleotide polymorphism

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