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Dual in-situ observation of tribochemical and morphological evolution of single-layer WS_(2)and multi-layer WS_(2)/C coatings

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Friction 2024年第7期12卷 1580-1598页

作者： Yuzhen LIU jae-ho han Shusheng XU Young Chan JUNG Dae-Eun KIM State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China Department of Mechanical Engineering Yonsei UniversitySeoul03722Republic of Korea Shandong Laboratory of Advanced Materials and Green Manufacturing at Yantai Yantai 264000China Yantai Zhongke Research Institute of Advanced Materials and Green Chemical Engineering Yantai 264000China

The outstanding tribological performance of transition metal dichalcogenides(TMDs)is attributed to their unique sandwich microstructure and low interlayer shear *** advantageous structure allows TMDs to demonstrate exceptional friction reduction ***,the incorporation of TMDs and amorphous carbon(a-C)in multi-layer structures shows excellent potential for further enhancing tribological and anti-oxidation *** carbon,known for its high ductility,chemical inertness,and excellent wear resistance,significantly contributes to the overall performance of these multi-layer *** gain an in-depth understanding of the tribological mechanism and evolution of TMDs’multi-layer coatings,a dual in-situ analysis was carried out using a tribometer equipped with a 3D laser microscope and a Raman *** innovative approach allowed for a comprehensive evolution of the tribological,topographical,and tribochemical characteristics of both single-layer WS_(2)and multi-layer WS_(2)/C coatings in real *** findings from the dual in-situ tribotest revealed distinct failure characteristics between the single-layer WS_(2)coating and the multi-layer WS_(2)/C *** single-layer WS_(2)coating predominantly experienced failure due to mechanical removal,whereas a combination of mechanical removal and tribochemistry primarily influenced the failure of the multi-layer WS_(2)/C *** tribological evolution process of these two coatings can be classified into four stages on the basis of their tribological behavior:the running-in stage,stable friction stage,re-deposition stage,and lubrication failure *** stage represents a distinct phase in the tribological behavior of the coatings and contributes to our understanding of their behavior during sliding.

关键词： In-situ analysis multi-layer coating tribology tribochemistry

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Fabrication and Mechanical Properties of Sm2O3 Doped CeO2 Reinforced Ti3AlC2 Nano Composite

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Journal of Rare Earths 2004年第Z2期22卷 85-88页

作者： jae ho han Sang Whan Park Young Do Kim Division of Materials Science & Engineering Hanyang UniversitySeoul133-791Korea Korea Institute of Science and TechnologyMulti-Functional Ceramics Research CenterSeoul136-791Korea Division of Materials Science & EngineeringHanyang UniversitySeoul133-791Korea

The fabrication process of Sm2O3 doped CeO2 reinforced Ti3AlC2 nano composites including the nano particle dispersion process by a hetero-coagulation process was developed using in-situ synthesis and densification process of Ti3AlC2. The effects of Sm2O2 doped CeO2 nano particles on mechanical properties of Ti3AlC2 were investigated. It was found that the presence of 20SDC nano particles in Ti3AlC2 was very effective to improve the mechanical properties of Ti3AlC2 without spoiling the unique characteristics of Ti3AlC2temary carbide.

关键词： nano ceramic composite Ti3AlC2 CeO2 fabrication rare earths

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High-resolution subsurface articular cartilage imaging based on Fourier-domain common-path optical coherence tomography

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Chinese Optics Letters 2010年第2期8卷 167-169页

作者： jae-ho han Xuan Liu Jin U. Kang Chul Gyu Song Department of Electrical and Computer Engineering Johns Hopkins University 3400 N. Charles St. Baltimore MD 21218 USA Division of Electronics and Information Engineering Center for Advanced Image and Information Technology Chonbuk National University Deokjin-Dong Jeonju 561-756 Korea

We demonstrate the subsurface imaging of an articular cartilage using Fourier-domain common-path optical coherence tomography. The bare fiber probe integrated with a hypodermic needle provides the rigidness required to perform lateral scanning with less microscale bending. By submerging both the probe and the specimen into saline solution, we not only reduce the beam divergence, but also increase the signal-to-noise ratio compared with the measurement in free space. Our system can differentiate the characteristic cartilage zones and identity various micro-structured defects in an ex vivo chicken knee cartilage, thus demonstrating that it could be used to conduct early arthritis diagnosis and intraoperative endo-microscopy.

关键词： High-resolution subsurface articular cartilage imaging based on Fourier-domain common-path optical coherence tomography

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One-step method to enhance biotribological properties and biocompatibility of DLC coating by ion beam irradiation

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Friction 2022年第7期10卷 1114-1126页

作者： Yuzhen LIU Kelun ZhanG jae-ho han Youn-hoo HWANG Shusheng XU Dae-Eun KIM Department of Mechanical Engineering Yonsei UniversitySeoul 03722Republic of Korea Department of Dermatology and Cutaneous Biology Research Institute Yonsei University College of MedicineSeoul 03722Republic of Korea State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China

A one-step method was developed to create a highly biocompatible micropatterned surface on a diamond-like carbon(DLC)through irradiation with a nitrogen ion beam and thus enhance the biocompatibility of osseointegrated surfaces and biotribological performance of articular *** biocompatibility and biotribological mechanisms were analyzed in terms of the structure and morphology of *** was demonstrated that a layer enriched in sp^(3) C-N bonds was formed on the surface of the DLC after nitrogen ion beam ***,with an increase in the radiation dose,the content of sp^(3) C-N on the DLC surface increased significantly,and the biocompatibility was positively correlated with *** adhesion of the MC3T3 osteoblasts increased significantly from 32%to 86%under an irradiation dose of 8×10^(15) ions/cm^(2).In contrast,the micropattern had a significant negative effect on the adhesion of the osteoblasts as it physically hindered cell expansion and *** micropattern with a depth of 37 nm exhibited good friction properties,and the coefficient of friction was reduced by 21%at relatively high speeds.

关键词： ion beam irradiation biocompatibility diamond-like carbon(DLC) in-vivo micropattern biotribological performance

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Microball lens integrated fiber probe for optical frequency domain imaging

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Chinese Optics Letters 2011年第9期9卷 29-31页

作者： jae-ho han J. U. Kang Department of Brain and Cognitive Engineering Korea University 6-1 Anaxn-Dong Sungbuk-Ku Seoul 136-713 South Korea Department of Electrical and Computer Engineering Johns Hopkins University 3400 N. Charles St. Baltimore MD 21218 USA

An integrated microball lens fiber catheter probe is demonstrated, which has better lateral resolution and longer working distance than a corresponding bare fiber probe with diverging beam for Fourier domain optical coherence tomography （FDOCT）. Simulation results are shown to gain the effect of the distance between the mieroball lens and the bare fiber to the focusing plane and beam width. The freedom of modifying the working distance and lateral resolution is shown. This is achieved by changing the gap distance between the single-mode fiber and the microball lens within the packaged surgical needle catheter without using an additional beam expander having a fixed length. The probe successfully acquired crosssectional images of ocular tissues from an animal sample with the proposed miniaturized imaging probe.

关键词： Microball lens integrated fiber probe for optical frequency domain imaging than

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Amylase level in extra hepatic bile duct in adult patients with choledochal cyst plus anomalous pancreatico-biliary ductal union

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World Journal of Gastroenterology 2005年第13期11卷 1965-1970页

作者： In-ho Jeong Yong-Sik Jung hong Kim Bong-Wan Kim Jung-Woon Kim Jeong hong Hee-Jung Wang Myung-Wook Kim Byung-Moo Yoo Jin-hong Kim jae-ho han Wook-Hwan Kim Department of Surgery Department of Gastroenterology Department of Pathology

AIM: To investigate the relationship between pancreatic amylase in bile duct and the clinico-pathological features in adult patients with choledochal cyst and anomalous pancreatico-biliary ductal union (APBDU).METhoDS: From 39 patients who underwent surgery for choledochal cyst between March 1995 and March 2003,we selected 15 adult patients who had some symptoms and were radiologically diagnosed as APBDU, and their clinico-pathological features were subsequently evaluated retrospectively. however, we could not obtain biliary amylase in all the patients because of the surgeon's ***, we measured the amylase level in gall bladder of 10 patients and in common bile duct of 11 ***: Levels of amylase in common bile duct and gall bladder ranged from 11 500 to 212 000 IU/L, and the younger the patients, the higher the biliary amylase level (r= -0.982, P＜0.01). Pathologically, significant correlation was found between the size of choledochal cyst and the grade of inflammation (r= 0.798,P＜0.01). And, significant correlation was found between the level of amylase in gall bladder and the grade of hyperplasia. On the other hand, there was no correlation to the age of symptomatic onset or inflammatory grade (r = 0.743, P＜0.05). Level of lipase was elevated from 6 000 to 159 000 IU/L in bile duct and from 14 400 to 117 000 IU/L in the gall bladder;however, there was no significant correlation with age or clinico-pathological ***: The results support the notion that amylase has a particular role in the onset of symptoms, and suggest that a large amount of biliary amylase induces early onset of symptom, thereby making early diagnosis possible.

关键词： Choledochal cyst Anomalous pancreaticobiliary ductal union Amylase Hyperplasia

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Nanoparticle Exsolution on Perovskite Oxides:Insights into Mechanism,Characteristics and Novel Strategies

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Nano-Micro Letters 2024年第2期16卷 312-346页

作者： Yo han Kim Hyeongwon Jeong Bo‑Ram Won Hyejin Jeon Chan‑ho Park Dayoung Park Yeeun Kim Somi Lee jae‑ha Myung Department of Materials Science and Engineering Incheon National UniversityIncheon 22012Republic of Korea

Supported nanoparticles have attracted considerable attention as a promising catalyst for achieving unique properties in numerous applications,including fuel cells,chemical conversion,and *** demonstrate high activity by expanding the number of active sites,but they also intensify deactivation issues,such as agglomeration and poisoning,*** for bottomup synthesis of supported nanoparticles has emerged as a breakthrough technique to overcome limitations associated with conventional *** are uniformly exsolved from perovskite oxide supports and socketed into the oxide support by a one-step reduction *** uniformity and stability,resulting from the socketed structure,play a crucial role in the development of novel ***,tremendous research efforts have been dedicated to further controlling exsolution *** effectively address exsolution at a more precise level,understanding the underlying mechanism is *** review presents a comprehensive overview of the exsolution mechanism,with a focus on its driving force,processes,properties,and synergetic strategies,as well as new pathways for optimizing nanocatalysts in diverse applications.

关键词： Supported nanoparticle Exsolution In situ growth Mechanism Perovskite oxide Catalyst

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Clean-DM1, a Korean Polyherbal Formula, Improves High Fat Diet-Induced Diabetic Symptoms in Mice by Regulating IRS/PI3K/AKT and AMPK Expressionsin Pancreas and Liver Tissues

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Chinese Journal of Integrative Medicine 2024年第2期30卷 125-134页

作者： Piao Wang Yi Liu Seok Yong Kang Chenzi Lyu Xiang han Tianjun ho Kyung jae Lee Xianglong Meng Yong-Ki Park Hyo Won Jung Department of Herbology College of Korean MedicineDongguk UniversityGyeongju 38066Korea College of Pharmacy&Graduate School of Pharmaceutical Sciences Ewha Womans UniversitySeoul 03760Korea Korean Medicine R&D Center Dongguk UniversityGyeongju 38066Korea Shanxi Key Laboratory of Traditional Herbal Medicines Processing Shanxi University of Chinese MedicineJinzhong(030619)ShanxiProvinceChina

Objective:To investigate the effects of Clean-DM1(C-DM1),a polyherbal formulation of Radix Scrophulariae,Radix Astragali,Rhizoma Atractylodis,and Radix Salviae Miltiorrhizae,on high-fat diet(HFD)-induced diabetes ***:The information about active components of C-DM1 extract and molecular mechanism was obtained from network pharmacology *** compounds of C-DM1 extract by high performance liquid chromatography-mass spectrometry(HPLC-MS)analysis were conducted for quality *** in vivo study,mice were induced diabetes by HFD for 12 *** mice in the normal group(Nor)were maintained with a regular diet and treated with saline by *** HFD model mice were randomly divided into 3 groups,including a HFD diabetic model group,a C-DM1 extract-administered group(C-DM1,500 mg/kg),and metformin-administered groups(Met,500 mg/kg),8 mice in each *** intake,body weight(BW),and fasting blood glucose(FBG)levels were recorded weekly for 4 *** 4 weeks of treatment,alanine aminotransferase(ALT),aspartate aminotransferase(AST),blood glucose,low-density lipoprotein cholesterol(LDL-C)were determined using an automated clinical chemistry analyzer,and homeostatic model for assessing insulin resistance(hoMA-IR)levels and oral glucose tolerance test(OGTT)were *** histopathological changes of liver and pancreatic tissues were observed by hematoxylin-eosin *** receptor substrate(IRS)/phosphatidylinositol 3 kinase(PI3K)/protein kinase B(AKT)and adenosine 5'-monophosphate-activated protein kinase(AMPK)expressions in liver and pancreas tissues were detected by Western blot ***:HPLC-MS identified dihydroisotanshinone,dihydroisotanshinone I,cryptotanshinone,harpagoside,and atractyloside A in C-DM1 *** administration of C-DM1 extract significantly decreased body weight,calorie intake,and the levels of blood glucose and insulin in the diabetic mice(P<0.05 or P<0.01).The C-DM1 extract administration improved the im

关键词： high-fat diet type 2 diabetes mellitus herbal formulation insulin receptor substrate/phosphatidylinositol 3 kinase/protein kinase B adenosine 5'-monophosphate-activated protein kinase network pharmacology high performance liquid chromatography-mass spectrometry analysis

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Varifocal occlusion in an optical see-through near-eye display with a single phase-only liquid crystal on silicon

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Photonics Research 2024年第4期12卷 833-853页

作者： WOONGSEOB han jae-WON LEE JUNG-YEOP SHIN MYEONG-ho ChoI HAK-RIN KIM jae-HYEUNG PARK Department of Electrical and Computer Engineering Inha University100 Inha-roMichuhol-guIncheon 22212Republic of Korea School of Electronic and Electrical Engineering Kyungpook National University80 Daehak-roBuk-guDaegu 41566Republic of Korea School of Electronics Engineering Kyungpook National University80 Daehak-roBuk-guDaegu 41566Republic of Korea Department of Information and Communication Engineering Inha University100 Inha-roMichuhol-guIncheon 22212Republic of Korea

We propose a near-eye display optics system that supports three-dimensional mutual *** exploiting the polarization-control properties of a phase-only liquid crystal on silicon (LCoS),we achieve real see-through scene masking as well as virtual digital scene imaging using a single *** depth control of the real scene mask and virtual digital image is also achieved by using a focus tunable lens (FTL) pair of opposite *** proposed configuration using a single LCoS and opposite curvature FTL pair enables the self-alignment of the mask and image at an arbitrary depth without distorting the see-through view of the real *** verified the feasibility of the proposed optics using two optical benchtop setups:one with two off-the-shelf FTLs for continuous depth control,and the other with a single Pancharatnam–Berry phase-type FTL for the improved form factor.

关键词： optics crystal phase

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Inhibiting scar formation via wearable multilayer stacked electret patch:Self-creation of persistent and customizable DC electric field for fibrogenic activity restriction

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InfoMat 2024年第3期6卷 66-80页

作者： Sung-Won Kim Sumin Cho Donghan Lee Jiyu Hyun Sunmin Jang Inwoo Seo Hyun Su Park Hee jae Hwang Hyung-Seop han Dae Hyeok Yang Heung jae Chun Suk ho Bhang Dongwhi Choi School of Chemical Engineering Sungkyunkwan UniversitySuwonRepublic of Korea Department of Mechanical Engineering(Integrated Engineering Program) Kyung Hee UniversityYonginGyeonggiRepublic of Korea Biomaterials Research Center Biomedical Research DivisionKorea Institute of Science and Technology(KIST)SeoulRepublic of Korea Department of Medical Life Sciences College of MedicineInstitute of Cell and Tissue EngineeringThe Catholic University of KoreaSeoulRepublic of Korea

Electrical stimulation has recently received attention as noninvasive treatment in skin wound healing with its outstanding biological property for clinical set***,the complexity of equipment for applying appropriate electrical stimulation remains an ongoing ***,we proposed a strategy for skin scar inhibition by providing electrical stimulation via a multilayer stacked electret(MS-electret),which can generate direct current(DC)electric field(EF)without any power supply *** addition,the MS-electret can easily control the intensity of EFs by simply stacking electret layers and maintain stable EF with the surface potential of 3400 V over 5 days owing to the injected charges on the electret *** confirmed inhibition of type 1 collagen andα-SMA expression of human dermal fibroblasts(hDFs)by 90%and 44%in vitro,indicating that the transition of hDFs to myofibroblasts was restricted by applying stable electrical *** further revealed a 20%significant decrease in the ratio of myofibroblasts caused by the MS-electret in *** findings present that the MS-electret is an outstanding candidate for effective skin scar inhibition with a battery-free,physiological electrical microenvironment,and noninvasive treatment that allows it to prevent external infection.

关键词： DC electric field dermal fibroblasts electret scar formation restriction self-creation of electrical stimulation

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