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Neuralgic amyotrophy with hourglass-like constrictions:A case report

World Journal of Clinical Cases 2024年第34期12卷 6728-6735页

作者： Mi-Hyeon Bang Ha-Lim Song Seok Hahn Wanil kim hwan-Kwon Do Department of Physical Medicine and Rehabilitation Haeundae Paik HospitalInje University College of MedicineBusan 48108South Korea Department of Radiology Haeundae Paik HospitalInje University College of MedicineBusan 48108South Korea Division of Biochemistry Department of Convergence Medical ScienceInstitute of Medical ScienceGyeongsang National University College of MedicineJinju 52727South Korea Department of Physical Medicine and Rehabilitation Dongnam Institute of Radiological and Medical SciencesBusan 46033South Korea

BACKGROUND Neuralgic amyotrophy(NA)is a rare disease with sudden upper limb pain followed by affected muscle *** most commonly affected area in NA is the upper part of the brachial plexus,and the paraspinal muscles are rarely affected(1.5%),making these cases difficult to distinguish from cervical *** SUMMARY A 76-year-old male presented to the emergency department with left hip pain *** undergoing left femoral neck fracture surgery,he experienced sudden left shoulder pain for 10 days with subsequent left arm *** spine computed tomography revealed mild right asymmetric intervertebral disc bulging with a decreased C5-6disc *** weeks later,an electrodiagnostic study confirmed brachial plexopathy findings involving the cervical *** resonance neurography was performed for a differential *** enhancement was identified at the upper trunk of the brachial plexus,including the C5 nerve root.A suprascapular nerve hourglass-like focal constriction(HLFC)was also identified,confirming *** being diagnosed with NA,the patient received 15 mg prednisolone,twice daily,for 3 *** therapy was initiated,including left arm strengthening exercises and electrical stimulation *** shoulder muscle strength significantly improved one CONCLUSION NA's unique features like HLFC and paraspinal involvement are crucial for accurate diagnosis,avoiding confusion with cervical radiculopathy.

关键词： Neuralgic amyotrophy Cervical radiculopathy Hourglass-like focal constriction Paraspinal muscle Magnetic resonance neurography Case report

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Regional anesthesia in a patient with primary ciliary dyskinesia:A case report

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World Journal of Clinical Cases 2024年第17期12卷 3183-3187页

作者： Hyung Joon Park Ye hwan kim Young Joon Yoon Sang Yun Cho Department of Anesthesiology and Pain Medicine Hanyang University Guri HospitalGuri-si 471-701Gyeonggi-doSouth Korea

BACKGROUND Primary ciliary dyskinesia(PCD)is an inherited autosomal-recessive disorder of impaired mucociliary clearance characterized by chronic respiratory diseases,otolaryngological diseases,central nervous system abnormalities,reproductive system abnormalities,and cardiac function *** anesthesia in these patients is associated with a higher incidence of respiratory complications than in patients without the *** SUMMARY A 16-year-old male patient was referred to the emergency room complaining of right ankle pain due to distal tibiofibular *** years prior,he had been diagnosed with *** that time,he had experienced several episodes of pneumonia,sinusitis,and chronic middle ear infections,for which he underwent surgical *** the current admission,he presented with cough and sputum but no other respiratory symptoms.A chest computed tomography scan revealed centrilobular ground-glass opacities in both lower lobes and a calcified nodule in the left lower *** the surgical procedure and postoperative pain management,combined spinal-epidural anesthesia was *** patient’s postoperative pain score was measured by the numerical rating scale(NRS).On the day of surgery,his NRS was 5 *** the second postoperative day,the NRS score had decreased to 2–3 *** epidural catheter was removed on the fourth day following the *** patient was subsequently discharged no respiratory *** We performed combined spinal-epidural anesthesia in a patient with *** patient experienced no additional respiratory complications and was discharged with a low NRS score for pain.

关键词： Primary ciliary dyskinesia Combined spinal-epidural anesthesia Patient controlled epidural analgesia Lower limb operation Case report

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Effect of smoking on the risk of gastrointestinal cancer after cholecystectomy: A national population-based cohort study

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World Journal of Gastrointestinal Surgery 2024年第9期16卷 2796-2807页

作者： Minseob kim Kyung-Do Han Seung-Hyun Ko Yoonkyung Woo jae Hyun Han Department of Surgery Graduate School of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Statistics and Actuarial Science Soongsil UniversitySeoul 06978South Korea Division of Endocrinology and Metabolism Department of Internal MedicineSt Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSuwon 16247South Korea Division of Hepatobiliary-Pancreas Surgery and Liver Transplantation Department of SurgerySt Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSuwon 16247South Korea

BACKGROUND The role of smoking in the incidence of colorectal cancer(CRC)or gastric cancer(GC)in populations undergoing cholecystectomy has not been *** To evaluate the effect of smoking on CRC or GC development in cholecystectomy *** A total of 174874 patients who underwent cholecystectomy between January 1,2010 and December 31,2017 were identified using the Korean National Health Insurance Service claims *** patients were matched 1:1 with mem-bers of a healthy population according to age and *** or GC risk after cholecystectomy and the association between smoking and CRC or GC risk in cholecystectomy patients were evaluated using adjusted hazard ratios(HRs)and 95%*** The risks of CRC(adjusted HR:1.15;95%CI:1.06-1.25;P=0.0013)and GC(adjusted HR:1.11;95%CI:1.01-1.22;P=0.0027)were significantly higher in cholecystectomy *** the population who underwent cholecystectomy,both CRC and GC risk were higher in those who had smoked compared to those who had never *** both cancers,the risk tended to increase in the order of non-smokers,ex-smokers,and current *** addition,a positive correlation was observed between the amount of smoking and the risks of both CRC and *** Careful follow-up and screening should be performed,focusing on the increased risk of gastrointestinal cancer in the cholecystectomy group,particularly considering the individual smoking habits.

关键词： Cholecystectomy Smoking,Gastric cancer Colon cancer Risk factor Hazard ratio

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乡镇学校体育教学现状及对策分析

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黑河学院学报 2024年第3期15卷 78-80,125页

作者：万传琦 In jae-kim 黑河学院黑龙江黑河164300 韩国湖西大学忠清南道牙山31499

我国拥有14亿多人口,其中将近4.77亿是农村人口,乡镇学校的体育教学是实现中国体育强国的关键所在,黑河市乡镇学校体育教学现状是各项目不均衡,极大限制了体育教学的全面性。影响体育教学不均衡的主要因素是教育政策、财政支持、师资力... 详细信息

我国拥有14亿多人口,其中将近4.77亿是农村人口,乡镇学校的体育教学是实现中国体育强国的关键所在,黑河市乡镇学校体育教学现状是各项目不均衡,极大限制了体育教学的全面性。影响体育教学不均衡的主要因素是教育政策、财政支持、师资力量及学生兴趣等,需要从管理、教师队伍、硬件设施等方面,贯彻全民健身下的学校体育教育,促进乡镇学校发展体育教育全面发展。

关键词：黑河市乡镇学校农村体育教学

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Hemophagocytic lymphohistiocytosis triggered by relapsing polychondritis:A case report

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World Journal of Orthopedics 2024年第8期15卷 813-819页

作者： Mi-Ran Han Jeong-hwan hwang Seungah Cha So-Yeon Jeon Kyu Yun Jang Namsu kim Chang-Hoon Lee Department of Internal Medicine Jeonbuk National University Medical SchoolJeonju 54907South Korea Department of Pathology Jeonbuk National University Medical SchoolJeonju 54907South Korea Department of Laboratory Medicine Jeonbuk National University Medical SchoolJeonju 54907South Korea

BACKGROUND Hemophagocytic lymphohistiocytosis(HLH)is a rare,life-threatening disorder caused by abnormal histiocytes and T cell *** adults,it is predominantly associated with infections,cancers,and autoimmune *** polychondritis(RP),another rare disease,is diagnosed based on symptoms without specific tests,featuring cartilage inflammation characterized by swelling,redness,and pain,rarely inducing *** SUMMARY A 74-year-old woman visited the emergency room with a fever of 38.6℃.Blood tests,cultures,and imaging were performed to evaluate *** showed increased fluorescent antinuclear antibody levels and mild cytopenia,with no other specific *** revealed lymph node enlargement was observed;however,biopsy results were *** re-evaluation of the physical exam,inflammatory signs suggestive of RP were observed in the ears and nose,prompting a tissue biopsy for ***,persistent fever accompanied by cytopenia prompted a bone marrow examination,revealing hemophagocytic *** finding no significant results in blood culture,viral markers,and tissue examination of enlarged lymph nodes,HLH was diagnosed by *** involved methylprednisolone followed by *** two months,bone marrow examination confirmed resolution of hemophagocytosis,with normalization of hyperferritinemia and *** Thorough physical examination enabled diagnosis and treatment of HLH trig gered by RP in patients presenting with fever of unknown origin.

关键词： Hemophagocytic lymphohistiocytosis Relapsing polychondritis Autoimmune disease Fever of unknown origin Steroid Case report

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Pain Efficacy of a Home-Based Low-Intensity Continuous Ultrasound Stimulator for Knee Arthritis: A Single-Arm, Open-Label, Prospective Clinical Trial

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Health 2024年第7期16卷 703-716页

作者： Md. Habibur Rahman Yeon-Gyu Jang Johny Bajgai Subham Sharma Kchorng Vira Abdul-Nasir Sofian Seong Hoon Goh Yundeok kim Cheol-Su kim Doo-Sup kim Kyu-jae Lee Department of Convergence Medicine Wonju College of Medicine Yonsei University Wonju Republic of Korea Department of Neurosurgery Wonju Severance Christian Hospital Wonju College of Medicine Yonsei University Wonju Republic of Korea Department of Global Medical Science Wonju College of Medicine Yonsei University Wonju Republic of Korea Department of Internal Medicine Division of Hematology-Oncology Wonju Severance Christian Hospital Wonju Republic of Korea Department of Orthopaedic Surgery Wonju College of Medicine Yonsei University Wonju Republic of Korea

1) Background: Osteoarthritis (OA) is defined as a degenerative joint disease that mainly affects the bone. This study aims to evaluate the effect of low-intensity continuous ultrasound (LICUS) treatment on the knee of osteoarthritis patients through home-based intervention using the LICUS medical device. 2) Methods: The clinical trials were designed in a single-arm, open-label, and intervention study. Thirty-five participants, including those who dropped out (12%), were screened and enrolled. The patients received LICUS (1.1 MHz, 1.5 W/cm2, collimated beams) on the knee by the instructions of the investigator at home (5 min/session, 3 times/day, for four-weeks). Outcome measures were assessed using the Visual Analog Scale (VAS) as a primary endpoint and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) as a secondary endpoint to evaluate pain relief and functional recovery of the knee between pre-treatment (baseline) and post-treatment (four-weeks). 3) Results: Knee pain scores measured using the VAS and WOMAC indices were significantly reduced after a four-week treatment with LICUS compared to baseline. Knee stiffness and functional capacity were significantly reduced after the LICUS application. In addition, there were no reports of adverse effects during the study period. 4) Conclusion: Long-term and home-based application of LICUS can be recommended as an alternative option for the treatment of OA patients, as evidenced by the effect of pain relief and knee function recovery.

关键词： Knee Osteoarthritis Low-Intensity Continuous Ultrasound Stimulator Clinical Trial Visual Analogue Scale Western Ontario and McMaster Universities Osteoarthritis Index

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Electrochemical characteristics of Al-Mg and Al-Mg-Si alloy in sea water

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中国有色金属学会会刊：英文版 2012年第S3期22卷 881-886页

作者： Seong-jong kim Seung-jun LEE jae-yong JEONG Kyu-hwan kim Division of Marine Engineering Mokpo Maritime University

Among Al alloys,particularly 5000 series Al Mg and 6000 series Al Mg Si often used as marine materials have excellent corrosion resistance,low melting point,and thereby showing recycling availability when compared to other *** experiments were conducted to select the most suitable material for marine *** electrochemical experiments were conducted in natural *** corrosion test was performed in many methods such as anodic/cathodic polarization and Tafel analysis using multi-channel potentio/galvanostat WMPG *** results,anodic and cathodic polarization behaviors indicate the characteristics of passive state and concentration polarization by reduction reaction in dissolved oxygen,which shows excellent electrochemical *** analysis results show no significant difference but 5052-O alloy of various alloy materials indicates the lowest corrosion current ***,5052-O Al alloy presents most anti-corrosion material in marine environment.

关键词： Al alloy ship electrochemical characteristics corrosion

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Oncology Research 2024年第2期32卷 421-432页

作者： SEUNG-HEE GWAK JUHYUN LEE EUNJI OH DOHYUN LEE WONSHIK HAN JONGMIN kim KYONG-TAI kim Department of Life Sciences Pohang University of Science and TechnologyPohang37673Korea R&D Center NovMetaPharma Co.Ltd.Pohang37668Korea Department of Surgery and Cancer Research Institute Seoul National University College of MedicineSeoul03080Korea Generative Genomics Research Center Global Green Research&Development CenterHandong Global UniversityPohang37554Korea

Genetic information is transcribed from genomic DNA to mRNA,which is then translated into threedimensional *** can undergo various post-transcriptional modifications,including RNA editing that alters mRNA sequences,ultimately affecting protein *** this study,RNA editing was identified at the 499th base(c.499)of human vaccinia-related kinase 2(VRK2).This RNA editing changes the amino acid in the catalytic domain of VRK2 from isoleucine(with adenine base)to valine(with guanine base).Isoleucine-containing VRK2 has higher kinase activity than the valine-containing VRK2,which leads to an increase in tumor cell *** we reported that VRK2 directly interacts with dystrobrevin-binding protein(dysbindin)and results in reducing its ***,we demonstrate that isoleucine-containing VRK2 decreases the level of dysbindin than valinecontaining *** interacts with cyclin D and thereby regulates its expression and *** reduction in the level of dysbindin by isoleucine-containing VRK2 further enhances the cyclin D expression,resulting in increased tumor growth and reduction in survival *** has also been observed that in patient samples,VRK2 level was elevated in breast cancer tissue compared to normal breast ***,the isoleucine form of VRK2 exhibited a greater increase in breast cancer ***,it is concluded that VRK2,especially dependent on the 167th variant amino acid,can be one of the indexes of tumor progression and proliferation.

关键词： VRK2 Kinase activity Breast cancer Tumor RNA editing Cell proliferation Cell growth

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Early bile duct cancer

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World Journal of Gastroenterology 2007年第25期13卷 3409-3416页

作者： jae Myung Cha Myung-hwan kim Se Jin Jang Department of Internal Medicine University of Kyunghee College of Medicine East-West Neo Medical Center Seoul Korea Department of Internal Medicine University of Ulsan College of Medicine Asan Medical Center Seoul Korea Department of Pathology University of Ulsan College of Medicine Asan Medical Center Seoul Korea

Bile duct cancers are frequently diagnosed as advanced diseases. Over half of patients with advanced bile duct cancer present with unresectable malignancies and their prognosis has been very poor even after curative resections. Although there has been a need to diagnose bile duct cancer at its eady stage, it has been a difficult goal to achieve due to our lack of knowledge regarding this disease entity. Early bile duct cancer may be defined as a carcinoma whose invasion is confined within the fibromuscular layer of the extrahepatic bile duct or intrahepatic large bile duct without distant metastasis irrespective of lymph node involvement. Approximately 3%-10% of resected bile duct cancers have been reported to be early cancers in the literature. The clinicopathological features of patients with early bile duct cancer differ from those of patients with advanced bile duct cancer, with more frequent asymptomatic presentation, characteristic histopathological findings, and excellent prognosis. This manuscript is organized to emphasize the need for convening an international consensus to develop the concept of early bile duct cancer.

关键词： Early bile duct cancer Prognosis Histopathology

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CaCO_3 film synthesis from ladle furnace slag: morphological change, new material properties, and Ca extraction efficiency

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International Journal of Minerals,Metallurgy and Materials 2018年第12期25卷 1447-1456页

作者： Seung-Woo Lee Yong-jae kim Jun-hwan Bang Soochun Chae Center for carbon mineralization Korea Institute of Geosciences and Mineral Resources Frontier in extreme physics Korea Research Institute of Standards and Science

A rapidly air-cooled ladle furnace slag(RA-LFS), which is a type of steelmaking slag discharged from a steel mill, was used to synthesize CaCO_3 film. The CaCO_3 film with 35 cm^2 of surface area was synthesized under atmospheric conditions, and the surface morphology of the CaCO_3 films was changed by using additives(CaCl_2 and ethylene glycol). Especially, the addition of CaCl_2 changed the surface morphology of CaCO_3 film with pore and induced new material properties, such as water adsorption. The(012) face of CaCO_3 film(calcite) was rapidly decreased by the addition of CaCl_2. The major components of RA-LFS were calcium(type of CaO, 53.9 wt%) and aluminum(type of Al_2 O_3, 37.9 wt%), and the major crystal phases of RA-LFS were C_3 S, C_(12) A_7, and C_3 A. The calcium extraction efficiency of RA-LFS was significantly increased after the CaCO_3 film synthesis. The material properties(hardness and elastic modulus) and the thermal characteristics of the CaCO_3 films were analyzed by nano-indentation and thermogravimetry–differential thermal analysis. The synthesized CaCO_3 films from RA-LFS and Ca(OH)_2(reagent) showed similarities in terms of their material properties and the decomposition temperature.

关键词： carbon dioxide ladle furnace slag carbonation calcium carbonate film calcium efficiency

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