检索结果-南通市图书馆

Risk factors for complications associated with upper gastrointestinal foreign bodies

World Journal of Gastroenterology 2015年第26期21卷 8125-8131页

作者： Kyong hee Hong Yoon jae Kim jae Hak Kim Song Wook Chun hee Man Kim jae hee cho Division of Gastroenterology Department of Internal MedicineDongguk University Ilsan HospitalGraduate School Division of Gastroenterology Department of Internal MedicineGachon University Gil Medical Center Division of Gastroenterology Department of Internal MedicineMyongji Hospital Division of Gastroenterology and Hepatology Department of Internal MedicineYonsei University Wonju College of Medicine

AIM: To investigate predictive risk factors associated with complications in the endoscopic removal of foreign bodies from the upper gastrointestinal ***: We retrospectively reviewed the medical records of 194 patients with a diagnosis of foreign body impaction in the upper gastrointestinal tract,confirmed by endoscopy,at two university hospital in South *** demographic data,including age,gender,intention to ingestion,symptoms at admission,and comorbidities,were *** features of the foreign bodies,such as type,size,sharpness of edges,number,and location,were *** data those were analyzed included duration of foreign body impaction,duration of endoscopic performance,endoscopic device,days of hospitalization,complication rate,30-d mortality rate,and the number of operationsrelated to foreign body ***: The types of upper gastrointestinal foreign bodies included fish bones,drugs,shells,meat,metal,and animal *** locations of impacted foreign bodies were the upper esophagus(57.2%),mid esophagus(28.4%),stomach(10.8%),and lower esophagus(3.6%).The median size of the foreign bodies was 26.2 ± 16.7 *** 194 patients,endoscopic removal was achieved in 189,and complications developed in 51 patients(26.9%).Significant complications associated with foreign body impaction and removal included deep lacerations with minor bleeding(n = 31,16%),ulcer(n = 11,5.7%),perforation(n = 3,1.5%),and abscess(n = 1,0.5%).Four patients underwent operations because of incomplete endoscopic foreign body *** multivariate analyses,risk factors for endoscopic complications and failure were sharpness(HR = 2.48,95%CI: 1.07-5.72; P = 0.034) and a greater than 12-h duration of impaction(HR = 2.42,95%CI: 1.12-5.25,P = 0.025).CONCLUSION: In cases of longer than 12 h since foreign body ingestion or sharp-pointed objects,rapid endoscopic intervention should be provided in patients with ingested foreign bodies.

关键词： Emergency department Foreign body Upper gastrointestinal tract Endoscopy Complication

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Weekend and nighttime effect on the prognosis of peptic ulcer bleeding

引用

World Journal of Gastroenterology 2012年第27期18卷 3578-3584页

作者： Young Hoon Youn Yong Jin Park jae Hak Kim Tae Joo Jeon jae hee cho Hyojin Park Department of Internal Medicine Gangnam Severance HospitalYonsei University College of MedicineSeoul 135-720South Korea Department of Internal Medicine Dongguk University Ilsan HospitalDongguk University College of MedicineGyeonggi-do 410-773South Korea Department of Internal Medicine Inje University Sanggye Paik HospitalInje University College of MedicineSeoul 139-707South Korea Department of Internal Medicine Kwandong University Myungji HospitalKwandong University College of MedicineGyeonggi-do 412-270South Korea

AIM:To evaluate whether weekend or nighttime admission affects prognosis of peptic ulcer bleeding despite early ***:Retrospective data collection from four referral centers,all of which had a formal out-of-hours emergency endoscopy service,even at weekends.A total of 388 patients with bleeding peptic ulcers who were admitted via the emergency room between January 2007 and December 2009 were *** parameters included time from patients' arrival until endoscopy,mortality,rebleeding,need for surgery and length of hospital ***:The weekday and weekend admission groups comprised 326 and 62 patients,*** were no significant differences in baseline characteristics between the two groups,except for younger age in the weekend *** patients (97%) had undergone early endoscopy,which resulted in a low mortality rate regardless of point of presentation (1.8% overall vs 1.6% on the weekend).The only outcome that was worse in the weekend group was a higher rate of rebleeding (12% vs 21%,P = 0.030).However,multivariate analysis revealed nighttime admission and a high Rockall score (≥ 6) as significant independent risk factors for rebleeding,rather than weekend ***:Early endoscopy for peptic ulcer bleeding can prevent the weekend effect,and nighttime admission was identified as a novel risk factor for rebleeding,namely the nighttime effect.

关键词： Early endoscopy Nighttime effect Pepticulcer bleeding Rebleeding Weekend effect

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A pilot study of single-use endoscopy in screening acute gastrointestinal bleeding

引用

World Journal of Gastroenterology 2013年第1期19卷 103-107页

作者： jae hee cho hee Man Kim Sangheun Lee Yu Jin Kim Ki Jun Han Hyeon Geun cho Si Young Song Division of Gastroenterology Department of Internal MedicineMyongji HospitalKwandong University College of MedicineGoyang 412-270South Korea Department of Internal Medicine Graduate SchoolYonsei University College of MedicineSeoul 120-752South Korea Division of Gastroenterology Department of Internal MedicineBrain Korea 21 Project for Medical ScienceSeverance Biomedical Science InstituteYonsei University College of MedicineSeoul 120-752South Korea

AIM:To investigate the feasibility of a single-use endoscopy as an alternative procedure to nasogastric lavage in patients with acute gastrointestinal(GI) ***:Patients who presented with hematemesis,melena or hematochezia were enrolled in this *** scan and conventional esophagogastroduodenoscopy(EGD) were subsequently *** bleeding was defined as blood in the stomach,and inactive bleeding was defined as coffee ground clots and clear fluid in the *** findings were recorded and ***:Between January and March,2011,13 patients that presented with hematemesis(n = 4),melena(n = 6),or bleeding from a previous nasogastric feeding tube(n = 3),were enrolled in this *** 12 patients with upper GI bleeding,the EG scan device revealed that 7 patients had active bleeding and 5 patients had inactive bleeding,whereas conventional EGD revealed that 8 patients had active bleeding and 4 patients had inactive *** sensitivity and specificity of the EG scan device was 87.5% and 100% for active bleeding,with conventional EGD serving as a *** complication were reported during the EG scan ***:The EG scan is a feasible device for screening acute upper GI *** may replace nasogastric lavage for the evaluation of acute upper GI bleeding.

关键词： Gastrointestinal hemorrhage Bleeding Endoscopy Nasogastric tube Lavage

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Dexamethasone inhibits hypoxia-induced epithelial-mesenchymal transition in colon cancer

引用

World Journal of Gastroenterology 2015年第34期21卷 9887-9899页

作者： Jung Ho Kim You-Jin Hwang Sang Hoon Han Young Eun Lee Saerom Kim Yoon jae Kim jae hee cho Kwang An Kwon Ju Hyun Kim Se-hee Kim Department of Internal Medicine Gachon University Gil Medical Center Division of Biological Science Gachon University of Medicine and Science Department of Internal Medicine Jeju National University School of Medicine Gachon Medical Research Institute Gachon University Gil Medical Center

AIM:To elucidate the effects of dexamethasone on hypoxia-induced epithelial-to-mesenchymal transition(EMT) in colon ***:Human colon cancer HCT116 and HT29 cells were exposed to normoxic(21%) and hypoxic(1%) conditions. First,the effect of dexamethasone on cell viability was examined by MTT cell proliferation assay. In order to measure the expression levels of EMT markers(Snail,Slug,Twist,E-cadherin,and integrin αVβ6) and hypoxia-related genes [Hypoxia-inducible factor-1α(HIF-1α) and vascular endothelial growth factor(VEGF)] by dexamethasone,quantitative real-time polymerase chain reaction and western blot analysis were performed. Furthermore,the morphological changes of colon cancer cells and the expression pattern of E-cadherin by dexamethasone were detected through immunocytochemistry. Finally,the effects of dexamethasone on the invasiveness and migration of colon cancer cells were elucidated using matrigel invasion,migration,and wound healing migration ***:Under hypoxia,dexamethasone treatment inhibited HIF-1α protein level and its downstream gene,VEGF m RNA level in the colon cancer cell lines,HCT116 and HT29. In addition,the presence of dexamethasone down-regulated the m RNA levels of hypoxia-induced Snail,Slug,and Twist,all transcriptional factors of EMT,as well as hypoxia-induced integrin αVβ6 protein level,a well-known EMT marker for colon cancer cells. Furthermore,reduced E-cadherin in hypoxic condition was found to be recoverable by treating with dexamethasone in both colon cancer cell lines. Similarly,under hypoxic conditions,dexamethasone restored the growth pattern and morphological phenotype reminiscent of colon cancer cells grown under normoxic conditions; dexamethasone blocked the migration and invasion of both colorectal cancer cell lines in ***:Our study suggested that dexamethasone has inhibitory effects on cell migration and invasion by suppressing EMT of colon cancer cell lines in hypoxic condition.

关键词： Dexamethasone Colon cancer Hypoxia Hypoxia-inducib

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium-induced colitis model

引用

World Journal of Gastroenterology 2017年第25期23卷 4559-4568页

作者： Seung Kak Shin jae hee cho Eui Joo Kim Eun-Kyung Kim Dong Kyun Park Kwang An Kwon Jun-Won Chung Kyoung Oh Kim Yoon jae Kim Division of Gastroenterology and Hepatology Department of Internal Medicine Gachon University Gil Medical Center

To evaluate the anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium (DSS)-induced colitis model. METHODSAn acute colitis mouse model was induced by oral administration of 5% DSS in the drinking water for 7 d. In the treated group, rosuvastatin (0.3 mg/kg per day) was administered orally before and after DSS administration for 21 d. On day 21, mice were sacrificed and the colons were removed for macroscopic examination, histology, and Western blot analysis. In the in vitro study, IEC-6 cells were stimulated with 50 ng/mL tumor necrosis factor (TNF)-α and then treated with or without rosuvastatin (2 μmol/L). The levels of reactive oxygen species (ROS), inflammatory mediators, and apoptotic markers were measured. RESULTSIn DSS-induced colitis mice, rosuvastatin treatment significantly reduced the disease activity index and histological damage score compared to untreated mice (P < 0.05). Rosuvastatin also attenuated the DSS-induced increase of 8-hydroxy-2’-deoxyguanosine and NADPH oxidase-1 expression in colon tissue. Multiplex ELISA analysis revealed that rosuvastatin treatment reduced the DSS-induced increase of serum IL-2, IL-4, IL-5, IL-6, IL-12 and IL-17, and G-CSF levels. The increased levels of cleaved caspase-3, caspase-7, and poly (ADP-ribose) polymerase in the DSS group were attenuated by rosuvastatin treatment. In vitro, rosuvastatin significantly reduced the production of ROS, inflammatory mediators and apoptotic markers in TNF-α-treated IEC-6 cells (P < 0.05). CONCLUSIONRosuvastatin had the antioxidant, anti-inflammatory and anti-apoptotic effects in DSS-induced colitis model. Therefore, it might be a candidate anti-inflammatory drug in patients with inflammatory bowel disease.

关键词： Oxidative stress Inflammatory bowel disease Rosuvastatin Apoptosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Endoscopic stenting for recurrence-related colorectal anastomotic site obstruction:Preliminary experience

引用

World Journal of Gastroenterology 2014年第38期20卷 13936-13941页

作者： Jung Ho Kim Jong Joon Lee jae hee cho Kyoung Oh Kim Jun-Won Chung Yoon jae Kim Kwang An Kwon Dong Kyun Park Ju Hyun Kim Department of Internal Medicine Gachon University Gil Medical Center

AIM: To evaluate the efficacy of stents in treating patients with anastomotic site obstructions due to cancer recurrence following colorectal surgery.

关键词： Colorectal neoplasms Endoscopy Intestinal obstruction Stents Surgical anastomosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Endoscopic features suggesting gastric cancer in biopsy-proven gastric adenoma with high-grade neoplasia

引用

World Journal of Gastroenterology 2014年第34期20卷 12233-12240页

作者： Jung Ho Kim Yoon jae Kim Jungsuk An Jong Joon Lee jae hee cho Kyoung Oh Kim Jun-Won Chung Kwang An Kwon Dong Kyun Park Ju Hyun Kim Department of Internal Medicine Gachon University Gil Medical CenterNamdong-guIncheon 405-760South Korea Department of Pathology Gachon University Gil Medical Center21 Namdong-daero 774 beon-gilNamdong-guIncheon 405-760South Korea

AIM: To elucidate the endoscopic features that predict the cancer following endoscopic submucosal dissection (ESD) in patients with high-grade neoplasia (HGN).

关键词： Stomach Neoplasms Carcinoma Adenoma Endoscopy Dissection Risk factors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Clinical Report on 3 cases of The patients of extruded disc Treated with Motion Style Treatment

引用

世界中医骨科杂志 2007年第1期9卷 7-11页

作者： jae-hee cho Hyo-eun Lee Joo-hyun Song Ja-young Moon Myung-jang Lim In Kang Hyoung-seok Jang Dept of Acupuncture ＆ Moxibustion Jaseng Hospital of Oriental Medicine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Enhancing ammonia production rates from electrochemical nitrogen reduction by engineering three-phase boundary with phosphorus-activated Cu catalysts

引用

Journal of Energy Chemistry 2023年第9期84卷 394-401页

作者： Jeehye Kim cho hee Lee Yong Hyun Moon Min hee Lee Eun Hyup Kim Sun hee choi Youn Jeong Jang jae Sung Lee School of Energy and Chemical Engineering Ulsan National Institute of Science and Technology(UNIST)Ulsan 44919Republic of Korea Department of Chemical Engineering Hanyang UniversitySeoul 04763Republic of Korea Pohang Accelerator Laboratory(PAL) Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea

Electrochemical N_(2) reduction reaction(eNRR) over Cu-based catalysts suffers from an intrinsically low activity of Cu for activation of stable N_(2) molecules and the limited supply of N_(2) to the catalyst due to its low solubility in aqueous ***,we propose phosphorus-activated Cu electrocatalysts to generate electron-deficient Cu sites on the catalyst surface to promote the adsorption of N_(2) *** eNRR system is further modified using a gas diffusion electrode(GDE) coated with polytetrafluoroethylene(PTFE) to form an effective three-phase boundary of liquid water-gas N_(2)-solid catalyst to facilitate easy access of N_(2) to the catalytic *** a result,the new catalyst in the flow-type cell records a Faradaic efficiency of 13.15% and an NH_(3) production rate of 7.69 μg h^(-1) cm^(-2) at-0.2 V_(RHE),which represent 3.56 and 59.2 times increases from those obtained with a pristine Cu electrode in a typical electrolytic *** work represents a successful demonstration of dual modification strategies;catalyst modification and N_(2) supplying system engineering,and the results would provide a useful platform for further developments of electrocatalysts and reaction systems.

关键词： Electrochemical nitrogen reduction reaction Ammonia production Phosphorous modified copper electrodes Gas diffusion electrodes Three-phase boundary PTFE coating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Study on adhesively-bonded surface of tapered double cantilever specimen made of aluminum foam affected with shear force

引用

Journal of Central South University 2015年第12期22卷 4521-4527页

作者：孙洪鹏 cho jae-ung Division of Mechanical Engineering Graduate School Kongju National University Division of Mechanical and Automotive Engineering Kongju National University

Aluminum foam is widely used in diverse areas to minimize the weight and maximize the absorption of shock energy in lightweight structures and various *** presents a number of advantages,such as low density,incombustibility,non-rigidity,excellent energy absorptivity,sound absorptivity and low heat *** aluminum foam with an air cell structure was placed under the TDCB Mode II tensile load by using Landmark equipment manufactured by MTS to examine the shear failure *** angle of the tapered adhesively-bonded surfaces of specimens was designated as a variable,and three models were developed with the inclined angles differing from one another at 6°,8° and 10°.The specimens with the inclined angles of 6°,8° and 10° have the maximum reaction forces of 168 N,194 N when the forced displacements are 6,5 and 4.2 mm *** are three specimens with the inclined angles of 10°,8° and 6° in the order of maximum reaction *** the analysis result,the maximum equivalent stresses of 0.813 MPa and 0.895 MPa happened when the forced displacements of 6 mm and 5 mm proceeded at the models of 6° and 8°,respectively.A simulation was carried out on the basis of finite element method and the experimental *** results of the experiment and the simulation analysis are shown not different from each other ***,only a simulation could be confirmed to be performed in substitution of an experiment,which is costly and time-consuming in order to determine the shearing properties of materials made of aluminum foam with artificial data.

关键词： adhesive displacement force reaction shearing fracture characteristic tapered double cantilever beam(TDCB)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：