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Auditing and design evaluation of building automation and control systems based on *** system audit-Danish case study

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energy and Built environment 2021年第1期2卷 34-44页

作者： jacob Alstrup engvang Muhyiddine Jradi Center for energy Informatics The Mcersk Mc-Kinney Moller InstituteUniversity of Southern Denmark5230 Odense MDenmark

Improving the energy performance of buildings will prove vital for countries worldwide to reduce their energy consumption and emissions.A key player in reaching this goal is building automation and control,as having well-designed and operated building automation and control systems(BACS)provide large capabilities in optimizing the energy performance of different *** this regard,building owners and planners must be able to assess and evaluate the current status of their BACS and identify potential *** there has been a large block of work done in Denmark along with regulations aiming to audit the overall building performance and individual systems characteristics,very little has been done in the field of auditing the building automation and control system and evaluating its structure and operation *** lack of systematic BACS auditing and evaluation in Danish buildings is addressed in this work with the first implementation and evaluation of the *** System methodology in a university office *** building was found to comply with the lowest automation and control class *** BACS retrofit packages were proposed and evaluated,and energy savings up to 28.5%are *** preliminary assessment results reported demonstrate the potential of building automation and control retrofit measures in a combined holistic improvement package alongside building envelope *** addition,the impact of the *** System improvements and labeling on the building’s classification based on the recent Danish building regulation BR18 is *** study discusses the feasibility of *** System tool implementation in Danish buildings and suggests *** also correlates and compares the *** System audit to the upcoming European SRI *** light of the huge efforts to digitalize the Danish energy sector,ensuring proper design and operation of BACS is of great ***,a systematic and methodical BACS auditing and eva

关键词： Building automation and control system Bacs System auditing Eu.bac system en 15,232 Danish case study

Water yield and biomass production for on a eucalypt-dominated Mediterranean catchment under different climate scenarios

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Journal of Forestry Research 2023年第5期34卷 1263-1278页

作者： Joao Rocha Ana Quintela Dalila Serpa Jan jacob Keizer Sérgio Fabres RAIZ-Forest and Paper Research Institute Quinta de S.FranciscoRua JoséEstevao(EN 230-1)3800–783 EixoAveiroPortugal Department of environment and Planning Centre of Environmental and Marine Studies(CESAM)University of AveiroCampus Universitário de Santiago3810–193 AveiroPortugal

Worldwide,forests are vital in the regulation of the water cycle regulation and in water balance *** of ecohydrological responses of production forests is essential to support management strategies,especially where water is already *** climatological patterns are expected to impact thermopluviometric regimes,water cycle components,hydrological responses,and plant physiology,evapotranspiration rates,crop productivity and land management *** work(1)assessed the impacts of different predicted climate conditions on water yield;(2)inferred the impacts of climate change on biomass production on eucalypt-to-eucalypt succes *** this end,the widely accepted Soil and Water Assessment Tool(SWAT)was run with the RCA,HIRHAM5 and RACMO climate models for two emission scenarios(RCP 4.5 and8.5).Three 12-year periods were considered to simulate tree growth under coppice *** results revealed an overall reduction in streamflow and water yield in the catchment in line with the projected reduction in total annual ***,HIRHAM5 and RACMO models forecast a slight shift in seasonal streamflow of up to 2 months(for2024-2048)in line with the projected increase in precipitation from May to *** biomass production,the extreme climate model(RCA)and severe emis sion scenario(RCP 8.5)predicted a decrease up to 46%.However,in the less extreme and more-correlated(with actual catchment climate conditions)climate models(RACMO and HIRHAM5)and in the less extreme emission scenario(RCP 4.5),biomass production increased(up to 20%),and the growth cycle was slightly *** was proven to be a valuable tool to assess climate change impacts on a eucalypt-dominated catchment and is a suitable decision-support tool for forest managers.

关键词： Climate scenarios Forested catchments Forest ecohydrological modelling Eucalypt biomass production SWAT model

Determining the spatial distribution of environmental and socio-economic suitability for human leptospirosis in the face of limited epidemiological data

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Infectious Diseases of Poverty 2022年第4期11卷 99-100页

作者： Maximiliano A.Cristaldi Thibault Catry Aurea Pottier Vincent Herbreteau Emmanuel Roux Paulina jacob M.Andrea Previtali Department of Natural Sciences College of Humanities and SciencesNational University of LitoralSanta FeArgentina 不详

Background:Leptospirosis is among the leading zoonotic causes of morbidity and mortality *** about spatial patterns of diseases and their underlying processes have the potential to guide intervention ***,leptospirosis is often an underreported and misdiagnosed disease and consequently,spatial patterns of the disease remain *** the absence of accurate epidemiological data in the urban agglomeration of Santa Fe,we used a knowledge-based index and cluster analysis to identify spatial patterns of environmental and socioeconomic suitability for the disease and potential underlying processes that shape ***:We geocoded human leptospirosis cases derived from the Argentinian surveillance system during the period 2010 to *** and socioeconomic databases were obtained from satelite images and publicly available platforms on the *** sets of human leptospirosis determinants were considered according to the level of their support by the literature and expert *** used the Zonation algorithm to build a knowledge-based index and a clustering approach to identify distinct potential sets of *** similarity and correlations between index,clusters,and incidence rates were ***:We were able to geocode 56.36%of the human leptospirosis cases reported in the national epidemiological *** knowledge-based index showed the suitability for human leptospirosis in the UA Santa Fe increased from downtown areas of the largest cities towards peri-urban and suburban *** analysis revealed downtown areas were characterized by higher levels of socioeconomic ***-urban and suburban areas encompassed two clusters which differed in terms of environmental *** highest incidence rates overlapped areas with the highest suitability scores,the strength of association was low though(CSc r=0.21,Pent a method to analyze the en

关键词： Spatial epidemiology Underreported misdiagnosed diseases environmental conditions Socioeconomic groups Knowledge-based index Cluster analysis

Giant dedifferentiated liposarcoma of the gastrocolic ligament:A case report

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World Journal of Gastrointestinal Surgery 2023年第10期15卷 2376-2381页

作者： Assamoi Brou Fulgence Kassi Kacou Sebastien Yenon Fian Marc Herve Kassi Adja jacob Adjeme Khader Morel Diarra Cynthia Bombet-Kouame Marcellin Kouassi Surgery and Surgical Specialities Medical Sciences Training and Research UnitAbidjan Felix Houphouet-Boigny UniversityAbidjan 01 BP V 34Cote d'Ivoire Surgery and Surgical Specialities Digestive Surgery UnitUniversity Hospital of CocodyAbidjan 01 BP V13Cote d'Ivoire

BACKGROUND Dedifferentiated liposarcoma(DDLS)has a worse prognosis and occurs most commonly in the retroperitoneal region and rarely in the intraperitoneal *** diagnosis was revolutionized by the combined contributions of histoimmuno-chemistry and molecular *** from surgery,there is no consensus on the optimal treatment for this chemoresistant *** SUMMARY A thirty-year-old black female presented with a large painful abdominal mass occupying nearly the entire abdomen and progressive weight loss was admitted for *** computed tomography showed a large heterogeneous mass of the mesentery that was sized 18 cm×16 cm in size and had heterogeneous contrast *** laparotomy,en bloc excision of the large and multilobulated gastrocolic ligament mass was *** initial postoperative histopathological diagnosis was undifferentiated ***,the results of immunohistochemistry and molecular biology allowed us to confirm the diagnosis of *** tumour followed an aggressive evolution with diffuse metastasis,causing the death of the patient less than 5 mo after the *** Dedifferentiated liposarcomas are rare tumours that typically originate in the retroperitoneum but may arise in unexpected locations.

关键词： Dedifferentiated liposarcoma Gastrocolic ligament mass en bloc excision Immunohistochemistry Molecular biology Worse prognosis Case report

Controlling Greenhouse Whitefly with Erectomoceru s eremicus Rose&Zolnerowich and Crude Plant Extracts of Garlic and Chilli Improves Yield of Tomato

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NASS Journal of Agricultural Sciences 2021年第1期3卷 1-9页

作者： jacob Masai Sumaili wanarusi Saidi Alice W.Kamau Department of Crops Horticulture and SoilsEgerton UniversityKenya

Despite its economic importance of tomato(Solamum lycopersicum L.),many growers are unable to achieve maximum yield of high quality due to insect pest *** study was aimed at determining the effec-tiveness of parasitoid Eretmocerus eremicus and crude plant extracts of garlic and chilli as an integrated alternative control method of greenhouse whitefly(GHW)on yield of tomato variety“Anna F1”The study *** at Egerton University using a split plot arrangement in ran-domized complete block design,replicated three *** was the main plot factor at two levels(with and without ***)while sprays of distilled water(negative control),Abamectin(positive control),chilli and garlic extracts formed the sub-plot *** on GHW incidence,population density,parasitisation rate,and yield was *** collected was subjected to analysis of variance and means of significant treatments separated using Tukey's test at p=*** extracts and *** helped to control whitefly population,infestation,and in en-hancing growth and yield of greenhouse tomato plants compared to where they were not *** plant extracts and/or *** can be used in the management of GHW and to improve tomato yields.

关键词： Biological control Crop protection Tomato growth

Optimized combinations of statins and azoles against Acanthamoeba trophozoites and cysts in vitro

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Asian Pacific Journal of Tropical Medicine 2019年第6期12卷 283-287页

作者： Ines Sifaoui Carmen M Martín-Navarro Atteneri López-Arencibia María Reyes-Batlle Basilio Valladares JoséE.Pinero Sutherland K Maciver jacob Lorenzo-Morales University Institute of Tropical Diseases and Public Health of the Canary Islands University of La LagunaCanary IslandsSpain Centre for Integrative Physiology Biomedical SciencesEdinburgh Medical SchoolUniversity of EdinburghScotlandUK

Objective: To evaluate the combination of several statins(atorvastatin, fluvastatin and simvastatin) and azoles(voriconazole, posaconazole and itraconazole) against Acanthamoeba spp. Methods: The efficiency of the different drug combinations against the trophozoite stage of different Acanthamoeba strains were evaluated by Alamar Blue assay. Effect on the cyst stage was observed by inverted microscope. Cytotoxicity of combinations of azoles and statins was evaluated by measuring the release of lactate dehydrogenase from a murine macrophage cell line. Results: Combinations of any of the tested statins and voriconazole or posaconazole were more efficient in inhibiting Acanthamoeba compared to statins or azoles individually. The drug combinations at the combined inhibitory concentrations 50% showed lower toxicity compared to that of the compounds ***: The combinations of statins together with voriconazole and posaconazole are more efficient than these drugs alone, and these combinations have lower cytotoxicity in mammalian cell lines.

关键词： Keratitis Voriconazole Posaconazole Atorvastatin Fluvastatin Simvastatin

enzymatic Synthesis and Structural Characterization of Rebaudioside D3, a Minor Steviol Glycoside of <i>Stevia rebaudiana</i>Bertoni

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American Journal of Plant Sciences 2017年第3期8卷 441-450页

作者： Guohong Mao Venkata Sai Prakash Chaturvedula jacob Edward Vick Oliver Yu Conagen Inc. Bedford MA USA Blue California Rancho Santa Margarita CA USA Wuxi New Way Biotechnology Ltd. Wuxi China

Rebaudioside D3, a novel steviol glycoside, is produced by specific UDP-glycosyltransferase of rebaudioside E, a minor steviol glycoside of Stevia rebaudiana Bertoni. The complete proton and carbon NMR spectral assignments of rebaudioside D3, 13-[(2-O-β-D-glucopyranosyl-6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) oxy] ent-kaur-16-en-19-oic acid-(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester, was achieved by the extensive 1D and 2D NMR (1H and 13C, TOCSY, HMQC, HMBC) as well as mass spectral data. Further, hydrolysis studies were performed on rebaudioside D3 using acid and enzymatic studies to identify aglycone and sugar residues in its structure. Rebaudioside D3 is detected in the commercial extract of the leaves of Stevia rebaudiana by LC-MS analysis, suggesting rebaudioside D3 is a natural steviol glycoside.

关键词： Stevia rebaudiana Diterpene Glycoside Structure Characterization Spectral Data LC-MS

Agro-Morphological Characterization of a Collection of Fonio [Digitaria exilis (Kippist.) Stapf.] Accessions from Burkina Faso

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American Journal of Plant Sciences 2023年第6期14卷 677-690页

作者： Balma Patrice Kabore Boukare Kiebre Mariam Kiebre Zakaria Sanou jacob Bationo/Kando Pauline Laboratoire Biosciences Unité de Formation et de Recherche en Sciences de la Vie et de la Terre Université Joseph KI-ZERBO Ouagadougou Burkina Faso Institut de l’environnement et de Recherches Agricoles/Farako-Bñ (INERA/Farako-B&#241) Bobo Dioulasso Burkina Faso

Considered as the oldest cereal, fonio (Digitaria exilis Stapf.) is grown in West Africa for its therapeutic virtues, its nutritional and organoleptic qualities. It plays an important socio-cultural and economic role for the populations of western Burkina Faso. However, very few studies on the genetic diversity of fonio have been carried out. This study aims to contribute to a better knowledge of the diversity of Digitaria exilis in Burkina Faso using agro-morphological descriptors. Thus, 60 accessions of fonio collected from western Burkina Faso were characterized using 21 agro-morphological characters according to an Alpha Latice design with three replications. The study showed morphological variability for most of the qualitative and quantitative characters studied. Principal component analysis (PCA) explained 56.07% of the variability. Hierarchical cluster analysis splits the accessions of the collection into four clusters using seven characters. These characters can constitute basic criteria for differentiating fonio accessions in Burkina Faso. The accessions of Group II have a long cycle and high production of grain, while the accessions of Group IV have a short cycle and low production of grain. The groups identified can serve as a starting point for fonio breeding in Burkina Faso.

关键词： Digitaria exilis Agro-Morphological Variability Accession Burkina Faso

National trends in alcohol and substance use among adolescents from 2005 to 2021:a Korean serial cross‑sectional study of one million adolescents

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World Journal of Pediatrics 2023年第11期19卷 1071-1081页

作者： Sangil Park Hyunju Yon Chae Yeon Ban Hyoin Shin Seounghyun Eum Seung Won Lee Youn Ho Shin Jung UShin Ai Koyanagi Louis jacob Lee Smith Chanyang Min AbdullahÖzgür Yeniova So Young Kim Jinseok Lee Vlasta Hadalin Rosie Kwon Min Ji Koo Guillaume Fond Laurent Boyer Sunyoung Kim Jong Woo Hahn Namwoo Kim Eléa Lefkir Victoire Bondeville Sang Youl Rhee Jae Il Shin Dong Keon Yon Ho Geol Woo Department of Neurology Kyung Hee University Medical Center23 Kyungheedae‑roDongdaemun‑guSeoul 02447South Korea Department of Medicine Kyung Hee University College of MedicineSeoulSouth Korea Department of Precision Medicine Sungkyunkwan University School of MedicineSuwonSouth Korea Department of Pediatrics CHA Gangnam Medical CenterCHA University School of MedicineSeoulSouth Korea Department of Dermatology CHA Bundang Medical CenterCHA University School of MedicineSeongnamSouth Korea Research and Development Unit Parc Sanitari Sant Joan de DeuCIBERSAMISCIIIBarcelonaSpain Catalan Institution for Research and Advanced Studies(ICREA) Pg.Lluis CompanysBarcelonaSpain Faculty of Medicine University of Versailles Saint-Quentin-en-YvelinesMontigny‑le‑BretonneuxFrance Centre for Health Performance and WellbeingAnglia Ruskin UniversityCambridgeUK Center for Digital Health Medical Science Research InstituteKyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Division of Gastroenterology Department of Internal MedicineFaculty of MedicineTokat Gaziosmanpaşa UniversityTokatTurkey Department of Otorhinolaryngology‑Head&Neck Surgery CHA Bundang Medical CenterCHA University School of MedicineSeongnamSouth Korea Department of Biomedical engineering Kyung Hee UniversityYonginSouth Korea Faculty of Medicine University of LjubljanaLjubljanaSlovenia Department of Biomedical engineering University of MichiganAnn ArborMIUSA Department of Human Biology University of TorontoTorontoONCanada AP-HM Aix-Marseille UniversityCEReSS-Health Service Research and Quality of Life CenterMarseilleFrance FondaMental Foundation CreteilFrance Department of Family Medicine Kyung Hee University College of MedicineSeoulSouth Korea Department of Pediatrics Seoul National University Bundang HospitalSeongnamSouth Korea Department of Neuropsychiatry Seoul National University HospitalSeoulSouth Korea Faculty of Medicine University of Rennes 1RennesFrance Department

Background Although previous studies have provided data on early pandemic periods of alcohol and substance use in adolescents,more adequate studies are needed to predict the trends of alcohol and substance use during recent periods,including the mid-pandemic *** study investigated the changes in alcohol and substance use,except tobacco use,throughout the pre-,early-,and mid-pandemic periods in adolescents using a nationwide serial cross-sectional survey from South *** Data on 1,109,776 Korean adolescents aged 13–18 years from 2005 to 2021 were obtained in a survey operated by the Korea Disease Control and Prevention *** evaluated adolescents’alcohol and substance consumption prevalence and compared the slope of alcohol and substance prevalence before and during the COVID-19 pandemic to see the trend *** define the pre-COVID-19 period as consisting of four groups of consecutive years(2005–2008,2009–2012,2013–2015,and 2016–2019).The COVID-19 pandemic period is composed of 2020(early-pandemic era)and 2021(midpandemic era).Results More than a million adolescents successfully met the inclusion *** weighted prevalence of current alcohol use was 26.8%[95%confidence interval(CI)26.4–27.1]from 2005 to 2008 and 10.5%(95%CI 10.1–11.0)in 2020 and *** weighted prevalence of substance use was 1.1%(95%CI 1.1–1.2)from 2005 to 2008 and 0.7%(95%CI 0.6–0.7)between 2020 and *** 2005 to 2021,the overall trend of use of both alcohol and drugs was found to decrease,but the decline has slowed since COVID-19 epidemic(current alcohol use:βdiff 0.167;95%CI 0.150–0.184;substance use:βdiff 0.152;95%CI 0.110–0.194).The changes in the slope of current alcohol and substance use showed a consistent slowdown with regard to sex,grade,residence area,and smoking status from 2005 to *** The overall prevalence of alcohol consumption and substance use among over one million Korean adolescents from the early and mid-stage(2020–2021)of the COVID

关键词： Alcohol Adolescent Corona virus disease 2019 South Korea Substance use