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Influence of La3+ ion in the yttria matrix in improving the microhardness of infrared transparent nano LaxY2-xO3 sintered via hybrid heating

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Journal of Advanced Ceramics 2017年第3期6卷 240-250页

作者： Jijimon K. THOMAS Mathew C. T. jacob koshy Sam SOLOMON Electronic Materials Research Laboratory Department of Physics Mar Ivanios College Thiruvananthapuram 695015 Kerala India

In the present work, hybrid sintering technique which couples the resistive heating and microwave heating is employed to sinter infrared transparent La0.15Y1.85O3 to 99.2% of the theoretical density for the first time to the best of our knowledge. The presence of La3+ in the yttria matrix improves the hardness properties to a greater extent without affecting the transmittance properties, but there is a deterioration in the thermal properties of the sample. So we have limited our studies to La0.15Y1.85O3 which shows better optical, thermal, and hardness properties. The pellets fabricated from the ultra-fine nano powder with average particle size of ~12 nm synthesized by combustion technique and sintered at 1430 °C with an average grain size of 0.22 μm show ~80.1% transmittance in the UV–visible region and 81% in mid infrared region. For a comparative study of the optical, mechanical, and thermal properties, two other variants of sintering strategies namely conventional sintering and microwave sintering are also employed. A comprehensive analysis on the hardness reveals that the hardness of the pellets sintered via hybrid heating is 9.73 GPa and is superior to the pellets sintered using the other two techniques. The thermal conductivity of the sample is also analyzed in detail. The results clearly indicate that the La0.15Y1.85O3 ultra-fine nano powder synthesised by the single-step combustion method and sintered via microwave hybrid heating shows better transmittance properties without compromising the mechanical properties, and can be used very effectively for the fabrication of infrared transparent windows and domes.

关键词： La 3+ concentration microhardness hybrid sintering infrared transparent ceramics thermal conductivity

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Bilateral serous retinal detachment in a case of eclampsia

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Health 2012年第1期4卷 13-14页

作者： Shiny Varghese jacob koshy Kumkum Avasthi 不详

Serous retinal detachment is a rare complication occurring in less than 1% of patients with eclampsia. We here report such a case. We strongly recommend the need for an eye check up in all patients of pregnancy induce... 详细信息

关键词： Serous Retinal Detachment Eclampsia Pregnancy Induced Hypertension

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Airborne Acoustic Transmission and Terrain Topography at SAINTGITS Amphitheatre:An Analysis of Outdoor Auditory Perception and Comparison of Contour Plots

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Sound & Vibration 2022年第3期56卷 255-274页

作者： jacob Thottathil Varghese Sajan Thomas Joselin Herbert Chacko Preno koshy Arjun Venugopal Department of Mechanical Engineering SAINTGITS College of EngineeringKottayam686532India APJ Abdul Kalam Technological University ThiruvanathapuramKerala695016India Part-Time Research Scholar Department of Mechanical EngineeringNICHENagercoil629180India Department of Mechanical Engineering NICHENagercoilTamil Nadu629180India

The arrangement of natural and physical features on the earth’s surface are a few among the countless items that govern the airborne acoustic transmission at boundary *** particular,if the acoustic waves are attributes of live concerts at open-air theatres,without losing the sheen and quality,the audience should certainly receive the unbroken depth of the ***,at all times,it is advisable to analyse the auditory receptiveness,particularly in all intended recreational *** current pandemic circumstances and the mandated COVID-19 prevention protocols encourage gatherings in naturally ventilated outdoor regions than confined *** work predicts and quantifies the acoustic experience at the naturally carved amphitheatre at SAINTGITS,an autonomous institution at the down South-West of the Indian *** entire recreational space at SAINTGITS AMPHI was separately modelled as a Base case and Advanced case,and were analysed using the acoustic modelling module of EASE Focus,a renowned simulation freeware,which is in strict adherence with the International *** variation in loudness received at the nearest and farthest ends of the amphitheatre was between 67 to 80 *** the Zero frequency SPL(Z-weighting)exhibited the loudness in the range of 81 to 85 dB and could maintain a safer auditory level for any human ear,it was confined to a hemispherical region near the sound source.A vertical beam angle of−4.0°was found to be effective *** procedures and analyses will certainly help the future organizers and stakeholders to effectively plan the resources to reap rich acoustic experience at terrain-centric *** surface topography and contours were plotted with another set of freeware,the CADMAPPER and the QUIKGRID,to compare terrain gradient with the known ***,this interdisciplinary research exhibits the extensive simulation capability of both EASE Focus and QUIKGRID and demonstrates the modelling v

关键词： Acoustic airborne transmission Sound Pressure Level(SPL) Amphitheatre SAINTGITS contour plot terrain topology safe acoustics

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Pegylated interferon alfa-2b plus ribavirin for treatment of chronic hepatitis C

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World Journal of Hepatology 2014年第7期6卷 520-526页

作者： PN Rao Abraham koshy jacob Philip Narayanan Premaletha Joy Varghese Krishnasamy Narayanasamy Samir Mohindra Nitin Vikas Pai Manoj Kumar Agarwal Ashokna Konar Hasmukh B Vora Department of Gastroenterology Asian Institute of Gastroenterology Hyderabad 500082 India Department of Hepatology Lakeshore Hospital Kochi 682040 India Department of Gastroenterology Cosmopolitan Hospital Thiruvananthapuram 695004 India Department of Gastroenterology Medical College Thiruvananthapuram 695011 India Department of Hepatology Global Hospitals and Health City Chennai 600100 India Department of Hepatology GGHand MMC Chennai 600003 India Department of Gastroenterology SGPGIMS Lucknow 226014 India Department of Gastroenterology Pai Clinic and Diagnostic Center Pune 411005 India Department of Gastroenterology Belle Vue Clinic Kolkata 700017 India Department of Gastroenterology PeerlessHospital and B.K. Roy Research Center Kolkata 700094 India Department of Gastroenterology Alka Hospital Ahmedabad 380019 India

AIM: To study the safety and efficacy of pegylated interferon alfa-2b, indigenously developed in India, plus ribavirin in treatment of hepatitis C virus(HCV). METHODS: One-hundred HCV patients were enrolled in an open-label, multicenter trial. Patients were treated with pegylated interferon alfa-2b 1.5 μg/kg per week subcutaneously plus oral ribavirin 800 mg/d for patients with genotypes 2 and 3 for 24 wk. The same dose of peginterferon plus weight-based ribavirin(800 mg/d for ≤ 65 kg; 1000 mg/d for > 65-85 kg; 1200 mg/d for > 85-105 kg; 1400 mg/d for > 105 kg body weight) was administered for 48 wk for patients with genotypes 1 and 4. Serological and biochemical responses of patients were ***: Eighty-two patients(35 in genotypes 1 and 4 and 47 in 2 and 3), completed the study. In genotype 1, 25.9% of patients achieved rapid virologic response(RVR): while the figures were 74.1% for early virologic response(EVR) and 44.4% for sustained virologic response(SVR). For genotypes 2 and 3, all patients bar one belonged to genotype 3, and of those, 71.4%, 87.5%, and 64.3% achieved RVR, EVR, and SVR, respectively. In genotype 4, 58.8%, 88.2%, and 52.9% of patients achieved RVR, EVR, and SVR, respectively. The majority of patients attained normal levels of alanine aminotransferase by 4-12 wk of therapy. Most patients showed a good tolerance for the treatment, although mild-to-moderate adverse events were exhibited; only two patients discontinued the study medication due to serious adverse events(SAEs). Eleven SAEs were observed in nine patients; however, only four SAEs were related to study ***: Peginterferon alfa-2b, which was developed in India, in combination with ribavirin, is a safe and effective drug in the treatment of HCV.

关键词： Hepatitis C virus Genotype Peginterferon alfa-2b Ribavirin Treatment

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