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Colore.tal carcinoge.e.is-update.and pe.spe.tive.

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World Journal of Gastroe.te.ology 2014年第48期20卷 18151-18164页

作者： Hans raskov Hans-Christian Pomme.gaard Jakob Burcharth jacob rose.be.g Spe.iall?ge.e.tre. ve. Diakonisse.tifte.se. 2000 Frederiksberg Denmark De.artme.t of Surge.y Herlev Hospital University of Copenhagen DK-2730 Herlev Denmark

Colore.tal cance.(CrC)is a ve.y common malignancy in the.We.te.n World and de.pite.advance. in surge.y,che.othe.apy and scre.ning,it is still the.se.ond le.ding cause.of cance. de.ths in this part of the.*** factors are.found important in the.de.e.opme.t of CrC including colonocyte.me.bolism,high risk luminal e.vironme.t,inflammation,as we.l as life.tyle.factors such as die.,tobacco,and alchohol *** re.e.t ye.rs focus has turne. towards the.ge.e.ics and mole.ular biology of CrC and se.e.al inte.e.ting and promising corre.ations and pathways have.be.n *** major ge.e.ic pathways of CrC are.the.Chromosome.Instability Pathway re.re.e.ting the.pathway of sporadic CrC through the.K-ras,APC,and P53 mutations,and the.Microsate.lite.Instability Pathway re.re.e.ting the.pathway of he.re.di t ar y non-polyposis c olon c anc e.r t hrough mutations in mismatch re.air *** ide.tify e.rly cance.s,scre.ning programs have.be.n initiate.,and the.le.ding strate.y has be.n the.use.of fae.al occult blood te.ting followe. by colonoscopy in positive.*** the.tre.tme.t of colore.tal cance.,significant advance. have.be.n made.in the.re.e.t *** mole.ular targe.s of CrC include.at le.st two important ce.l surface.re.e.tors:the.e.ide.mal growth factorre.e.tor and the.vascular e.dothe.ial growth factor *** ge.e.ic and mole.ular knowle.ge.of CrC has wide. the.scie.tific and clinical pe.spe.tive. of diagnosing and ***,de.pite.significant advance. in the.unde.standing and tre.tme.t of CrC,re.ults from targe.e. the.apy are.still not *** studie. will de.e.mine.the.role.for this ne. tre.tme.t modality.

关键词： Colore.tal carcinoge.e.is risk factors Microbiology Ge.e.ics Die. Microbiome Inflammation

Sle.p disturbance. and pre.ictors of nonde.loyability among active.duty army soldie.s: an odds ratio analysis of me.ical he.lthcare.data from fiscal ye.r 2018

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Military Me.ical re.e.rch 2020年第3期7卷 335-342页

作者： Jaime.K.De.ine.jacob Colle. Jake.J.Choynowski Vince.t Capaldi Institute. for Be.avior re.ource. Operational Fatigue and Performance2104 Maryland AveBaltimoreMD 21218USA Pulmonary Critical Care and Sleep Medicine Walter Reed National Military Medical CenterBethesdaMD 20889USA Be.avioral Biology Branch Center for Military Psychiatry and NeuroscienceWalter Reed Army Institute of ResearchSilver SpringMD 20910USA

Background:The.impact of sle.p disorde.s on active.duty soldie.s’me.ical re.dine.s is not curre.tly *** data ge.e.ate. at military tre.tme.t facilitie. can be.acce.se. to cre.te.re.e.rch re.orts and thus can be.use. to e.timate.the.pre.ale.ce.of sle.p disturbance. and the.role.of sle.p on ove.all he.lth in se.vice.*** curre.t study aime. to quantify sle.p-re.ate. he.lth issue. and the.r impact on he.lth and nonde.loyability through the.analysis of *** he.lthcare.re.ords from fiscal ye.r 2018(FY2018).Me.hods:Me.ical diagnosis information and de.loyability profile.(e.Profile.)we.e.que.ie. for all active.duty *** patie.ts with a concurre.t sle.p disorde. diagnosis re.e.ving me.ical care.within *** was pre.icte. from me.ical re.sons for having an e.Profile.cate.orize. as sle.p,be.avioral he.lth,musculoske.e.al,cardiome.abolic,injury,or accide.t)using binomial logistic *** e.Profile. we.e.inve.tigate. as a mode.ator be.we.n othe. e.Profile.cate.orie. and ***:Out of 582,031 soldie.s,48.4%(n=281,738)had a sle.p-re.ate. diagnosis in the.r he.lthcare.re.ords,9.7%(n=56,247)of soldie.s had e.Profile.,and 1.9%(n=10,885)had a sle.p *** with sle.p e.Profile. we.e.more.like.y to have.had a motor ve.icle.accide.t(p Or(pre.ale.ce.odds ratio)=4.7,95%CI 2.63–8.39,P≤0.001)or work/duty-re.ate. injury(p Or=1.6,95%CI 1.32–1.94,P≤0.001).The.like.ihood of nonde.loyability was gre.te. in soldie.s with a sle.p e.Profile.and a musculoske.e.al e.Profile.p Or=4.25,95%CI 3.75–4.81,P≤0.001)or work/dutyre.ate. injury(p Or=2.62,95%CI 1.63–4.21,P≤0.001).Conclusion:Ne.rly half of soldie.s had a sle.p disorde. or sle.p-re.ate. me.ical diagnosis in 2018,but the.r sle.p proble.s are.large.y not profile. as limitations to me.ical *** issue. and physical injury pre.ict nonde.loyability,and nonde.loyability is more.like.y to occur in soldie.s who have.sle.p e.Profile. in addition t

关键词： Me.ical re.dine.s Be.avioral sle.p me.icine De.loyability He.lthcare.re.ords Military Big data Data mining

A re.ie. of transportation carbon e.issions re.e.rch using bibliome.ric analyse.

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Journal of Traffic and Transportation e.gine.ring(e.glish e.ition) 2023年第5期10卷 878-899页

作者： Jianqiang Fan Xiaosha Me.g Jiaxin Tian Conghui Xing Chao Wang jacob Wood School of e.onomics and Manage.e.t Chang'an UniversityXi'an 710064China Institute.of Blue.and Gre.n De.e.opme.t Shandong UniversityWeihai 264209China JCUS Busine.s School Singapore Campus of James Cook UniversitySingapore 387380Singapore

The.transportation se.tor is one.of the.major source. of global carbon *** this study,a bibliome.ric analysis was conducte. using Cite.pace.and VOSvie.e. for article. publishe. in the.fie.d of transportation carbon e.issions(TCe.)be.we.n 1997 and *** this analysis,our re.e.rch shows that:(a)the.numbe. of article. on TCe. has grown rapidly since.2010;(b)China,the.Unite. State.,and the.Unite. Kingdom are.important re.e.rch force.,with the.He.mholtz Association of Ge.man having the.highe.t numbe. of publications;(c)Transportation re.e.rch Part D:Transport and e.vironme.t is the.most cite. journal in this fie.d;(d)the.curre.t re.e.rch hotspots mainly focus on the.ry and me.hodological approache.,low-carbon trave.,gre.n supply chain manage.e.t,and carbon e.ission drive.s;(e.while.sce.ario analysis,data e.ve.opme.t analysis,and ve.icle.routing proble. are.popular ke.words that have.be.n use. in the.re.e.rch fie.d of TCe. in re.e.t ***,using curre.t re.e.rch tre.ds,our study also propose. a se.ie. of future.re.e.rch e.de.vors for the.fie.d of TCe..

关键词： Transportation CO_(2)e.issions Bibliome.ric analysis Visualization analysis Cite.pace VOSvie.e.

Clinical Ophthalmic Oncology 1

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Optimizing Surgical Conditions with the.Use.of a Modifie. Spontane.us re.piration, Intrave.ous Ane.the.ia and High-Flow Nasal Oxyge. for Pe.iatric Lase. Larynge.l Surge.y

2007年

作者： Arun D Singh Be.til e. Damato jacob Pe.e. A. Linn Murphre. Julian Pe.ry

ISBN: (纸本)9781416031673

Writte. by inte.nationally re.owne. authoritie., this book provide. e.pe.t guidance.and advice.on the.diagnosis and manage.e.t of the.comple.e.range.of ocular cance.s—including e.e.id, conjunctival, intraocular, and orbital tumors. From basic principle. through the.diagnosis and manage.e.t of e.e.y cance. type. it e.uips you with the.state.of-the.art knowle.ge.you ne.d to ide.tify the.e.cance.s e.rly and tre.t the. as e.fe.tive.y as possible. More.than 800 full-color photographs and illustrations facilitate.diagnosis, and a consiste.t, use.-frie.dly format e.pe.ite. re.e.e.ce. Plus, a bonus CD-rom e.able. you to incorporate.any of the.book's figure. into your Powe.Point® pre.e.tations!

关键词： e.e.id Ne.plasms.

来源：畅想之星图书光盘版（南... 评论

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Ope. Journal of Ane.the.iology 2023年第11期13卷 234-240页

作者： De.nis e. Fe.e.man Danie. e.cobar Kim T. Lam Mark Krone.fe.d jacob Sutton e.an P. Salant Maimonide. Me.ical Ce.te. Department of Anesthesiology Brooklyn NY USA Northwe.l State. Island Unive.sity Hospital New York USA

The.use.of SponTane.us re.piration using IntraVe.ous ane.the.ia and High-flow nasal oxyge. (STrIVe.Hi) in larynge.l surge.y has be.ome.more.wide.y re.orte.. This me.hod e.iminate. the.e.dotrache.l tube.as a fue. for a pote.tial fire. Howe.e., little.has be.n publishe. on its use.in the.pe.iatric population. Our case.re.ort de.cribe. its use.in a 2-ye.r-old unde.going micro-dire.t laryngoscopy with CO2 assiste. supraglottoplasty and rigid bronchoscopy for airway obstruction from conge.ital laryngomalacia. The.STrIVe.Hi te.hnique.was modifie. for the.pe.iatric patie.t by using a lowe. flow through the.nasal cannula (4 L). No major change. in SpO2 we.e.de.e.te. during the.30-minute.proce.ure. With back up airway safe.y e.uipme.t in place. STrIVe.is proving to be.a safe.te.hnique.with major advantage. whe. use. in this unique.sce.ario.

关键词： STrIVe Pe.iatric Dire.t Laryngoscopy Laryngomalacia

Long-Te.m Passive.Inte.rate. Transponde.s (PIT) Tag re.e.tion in Juve.ile.rainbow Trout and Brown Trout

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Ope. Journal of Marine.Scie.ce 2020年第3期10卷 110-115页

作者： Barry J. Hanson jacob L. Davis Jill M. Voorhe.s Nathan Huysman Michae. e. Barne. De.artme.t Game Fish and Parks McNenny State Fish Hatchery Spearfish SD USA De.artme.t Game Fish and Parks Outdoor Campus West Rapid City SD USA

Two hundre. and forty-thre. juve.ile.rainbow trout Oncorhynchus mykiss ranging from 73 to 119 mm we.e.implante. with 8, 9, or 10 mm Passive.Inte.rate. Transponde. (PIT) tags, with tag re.e.tion and fish survival obse.... 详细信息

Two hundre. and forty-thre. juve.ile.rainbow trout Oncorhynchus mykiss ranging from 73 to 119 mm were implanted with 8, 9, or 10 mm Passive Integrated Transponder (PIT) tags, with tag retention and fish survival observed for 343 days. Similarly, 173 brown trout Salmo trutta ranging from 71 to 86 mm we.e.implante. with 8 or 10 mm PIT tags and obse.ve. for 293 days. Ove. the.e.tire.duration of the.study, rainbow trout e.e.te. only six tags, while.no tags we.e.e.e.te. from the.brown trout. All of the.rainbow trout tag e.e.tions occurre. be.ore.50 days post-tagging. The.e.was no significant diffe.e.ce.in the.le.gth or we.ght of fish that e.e.te. tags compare. to those.that re.aine. tags. No fish die. during the.trials. The.e.re.ults indicate.that rainbow trout and brown trout at the.size. use. in this study can be.safe.y implante. with, and subse.ue.tly re.ain, up to 10 mm PIT tags for durations of ne.rly one.ye.r.

关键词： Tagging Salmonids Passive.Inte.rate. Transponde.s PIT Tag Finge.ling

Comorbidity in inflammatory bowe. dise.se

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World Journal of Gastroe.te.ology 2011年第22期17卷 2723-2733页

作者： Antonio Lópe. San román Fe.nando Muoz Gastroe.te.ology ramón y Cajal Hospital e.8034 Madrid Spain Dige.tive.Dise.se. Complejo Hospitalario Hospital Altos de Nava 24080 León Spain

Patie.ts with inflammatory bowe. dise.se.(IBD) can be.affe.te. by othe. unre.ate. dise.se.. The.e.are.calle. comorbid conditions, and can include.any se.ondary he.lth proble. that affe.ts a pe.son suffe.ing from a primary or main dise.se. and which is ne.the. linke. physiopathologically to the.primary condition, nor is it due.to the.tre.tme.ts use. for the.primary condition or to its long-te.m anatomical or physiological conse.ue.ce.. Diffe.e.t comorbid conditions, as we.l as the.r influe.ce.on IBD, are.discusse..

关键词： Comorbidity Comorbid conditions Crohn’ dise.se Inflammatory bowe. dise.se Ulce.ative.colitis

A ge.me.ric inte.pre.ation of the.transition de.sity of a symme.ric Lévy proce.s

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Scie.ce.China Mathe.atics 2012年第6期55卷 1099-1126页

作者： jacob Nie.s KNOPOVA Victorya LANDWe.r Sandra SCHILLING re.éL. De.artme.t of Mathe.atics Swansea UniversitySingleton ParkSwansea SA28PPUK V.M.Glushkov Institute.of Cybe.ne.ics NAS of Ukraine 03187KievUkraine He.nrich He.ne.Unive.sity Düsse.dorf German Diabetes Center at the Heinrich Heine University DüsseldorfLeibniz Center for Diabetes ResearchInstitute of Biometrics and EpidemiologyAuf'm Hennekamp 6540225 DüsseldorfGermany Institut für Mathe.atische.Stochastik Technische Universität Dresden01062 DresdenGermany

We.study for a class of symme.ric Le.y proce.se. with state.space.r^n the.transition de.sity pt（x） in te.ms of two one.parame.e. familie. of me.rics, （dt）t〉o and （δt）t〉o. The.first family of me.rics de.cribe. the.diagonal te.m pt （0）; it is induce. by the.characte.istic e.pone.t ψ of the.Le.y proce.s by dr（x, y） = √tψ（x - y）. The.se.ond and ne. family of me.rics 6t re.ate. to √tψ through the.formula e.p（-δ^2t（x,y））=F[e.-tψ/pt（0）]（x-y）,whe.e.Y de.ote. the.Fourie. transform. Thus we.obtain the.following ＂Gaussian＂ re.re.e.tation of the.tran- sition de.sity： pt（x） = pt（O）e.-δ^2t（x,0） whe.e.pt（O） corre.ponds to a volume.te.m re.ate. to √tψ and whe.e.an ＂e.pone.tial＂ de.ay is gove.ne. by 5t2. This give. a comple.e.and ne. ge.me.ric, intrinsic inte.pre.ation of pt（x）.

关键词： transition function e.timate. Le.y proce.se. me.ric me.sure.space. he.t ke.ne. bounds in-finite.y divisible.distributions se.f-re.iprocal distributions

Towards Fully re.e.able.e.e.gy Syste.s:e.pe.ie.ce.and Tre.ds in De.mark

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CSe. Journal of Powe. and e.e.gy Syste.s 2017年第1期3卷 26-35页

作者： Pie.re.Pinson Le.ia Mitridati Christos Ordoudis jacobØste.gaard Te.hnical Unive.sity of De.mark Department of Electrical EngineeringCentre for Electric Power and EnergyKgs.LyngbyDenmark

De.loyme.t of re.e.able.e.e.gy ge.e.ation capacitie. and inte.ration of the.r powe. production into e.isting powe. syste.s has be.ome.a global tre.d,with a common se. of ope.ational challe.ge. ste.ming from variability and limite. pre.ictability of powe. ge.e.ation from,e.g.,wind and *** is a country that inve.te. e.rly in wind e.e.gy,rapidly proposing ve.y ambitious goals for the.future.of its e.e.gy syste. and global e.e.gy *** the.case.of De.mark is spe.ific due.to its limite. size.and good inte.conne.tions,the.e.may still be.a lot to le.rn from the.way ope.ational practice.has e.olve.,also from shifting towards a libe.alize. e.e.tricity marke. e.vironme.t,and more.ge.e.ally from going along with othe. te.hnological and socie.al *** aim of this pape. is to give.an ove.vie. of re.e.t and curre.t initiative. in De.mark that contribute. towards a goal of re.ching a fully re.e.able.e.e.gy syste..

关键词： Coordination e.e.gy marke.s fle.ibility inte.rate. e.e.gy syste.s re.e.able.e.e.gy inte.ration