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Histopathological analysis of infiltrating T cell subsets in acute T cell-mediated rejection in the kidney transplant

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World Journal of Transplantation 2017年第4期7卷 222-234页

作者： Francisco Salcido-Ochoa Susan Swee-Shan Hue Siyu Peng Zhaoxiang Fan Reiko Lixiang Li jabed iqbal John Carson Allen Jr Alwin Hwai Liang Loh Tregs and HLA Research Force and Renal Medicine Department Singapore General Hospital Tregs and HLA Research Force and Department of Pathology National University Hospital Tregs and HLA Research Force and Yong Loo Lin School of Medicine National University of Singapore Department of Pathology and Laboratory Medicine KK Women’s and Children’s Hospital Department of Pathology Singapore General Hospital Centre for Quantitative Medicine Duke-NUS Graduate Medical School

AIM To compare the differential immune T cell subset com-position in patients with acute T cell-mediated rejection in the kidney transplant with subset composition in the absence of rejection, and to explore the association of their respective immune profiles with kidney transplant *** A pilot cross-sectional histopathological analysis of the immune infiltrate was performed using immunohistochemistry in a cohort of 14 patients with acute T cellmediated rejection in the kidney transplant and 7 kidney transplant patients with no rejection subjected to biopsy to investigate acute kidney transplant dysfunction. All patients were recruited consecutively from 2012 to 2014 at the Singapore General Hospital. Association of the immune infiltrates with kidney transplant outcomes at up to 54 mo of follow up was also explored *** In a comparison to the absence of rejection, acute T cell-mediated rejection in the kidney transplant was characterised by numerical dominance of cytotoxic T lymphocytes over Foxp3^+ regulatory T cells, but did not reach statistical significance owing to the small sample size in our pilot study. There was no obvious difference in absolute numbers of infiltrating cytotoxic T lymphocytes, Foxp3^+ regulatory T cells and Th17 cells between the two patient groups when quantified separately. Our exploratory analysis on associations of T cell subset quantifications with kidney transplant outcomes revealed that the degree of Th17 cell infiltration was significantly associated with shorter time to doubling of creatinine and shorter time to transplant *** Although this was a small pilot study, results support our suspicion that in kidney transplant patients the immune balance in acute T cell-mediated rejection is tilted towards the pro-rejection forces and prompt larger and more sophisticated studies.

关键词： Acute T cell-mediated rejection in the kidney transplant Banff classification Cytotoxic T cell Regulatory T cell Th17 cell

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Pervasiveness of microplastics in the gastrointestinal tract of some selected fish species from Turag River alongside the capital city of Bangladesh

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Emerging Contaminants 2024年第3期10卷 77-85页

作者： HM Shahnewaz Khan jabed Hasan Mohammed Manik Murad Ahmed Farukh Md Shahjahan Department of Environmental Science Bangladesh Agricultural UniversityMymensingh2202Bangladesh Laboratory of Fish Ecophysiology Department of Fisheries ManagementBangladesh Agricultural UniversityMymensingh2202Bangladesh

Microplastics(MPs)are synthetic contaminants that have received global attention due to their ubiquitous occurrence,extreme durability,and capacity to harm ecosystems and human *** study investigated the occurrence of MPs in three fish species(Channa striata,Puntius sophore and Anabas testudineus)collected from two locations(Ashulia Bridge and Mirpur Road)of the Turag River,which flows alongside the Dhaka city,*** abundance(items/individuals)was highest in Channa striata(3.8±0.6)from the Ashulia Bridge area and lowest in Puntius sophore(1.8±0.4)from the Mirpur Road *** was found to be the most dominant(89e93%)form of MPs followed by fragments(21 e35%),films(0e26%)and foams(0e5%).The dominant color of MPs was blue(69e83%),then red(20 e33%),black(11e14%),green(8e20%),and purple(6e8%).The majority(56e71%)of the MPs assessed were<0.5 mm in size,followed by 0.5e1.0 mm(29e33%)and 1e5 mm(38e53%).ATR-FTIR examination revealed three specific polymer varieties-PP(40%),PS(30%)and LDPE(30%).The results of this study provided a baseline of MPs pollution in one of the major protein sources freshwater fishes and raised concern on public health particularly who consume fishes from the urban waterways.

关键词： Microplastics Polymer Bangladesh Turag river ATR-FTIR

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Blockchain-based COVID vaccination registration and monitoring

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Blockchain(Research and Applications) 2022年第4期3卷 44-55页

作者： Shirajus Salekin Nabil Md Sabbir Alam Pran Ali Abrar Al Haque Narayan Ranjan Chakraborty Mohammad jabed Morshed Chowdhury Md Sadek Ferdous Daffodil International University Dhaka1207Bangladesh La Trobe University VIC3086Australia BRAC University Dhaka1212Bangladesh

COVID-19 has changed almost all aspects of our *** around the world have imposed lockdowns to slow down the ***,we have found the vaccine,in fact,a good number of ***,managing the testing and vaccination process of the total population is a mammoth ***,there are always delays or data silo problems in multi-organizational ***,streamlining this process is vital to improve efficiency and save more *** of its effective data sharing mechanism among different entities with a number of security features,blockchain can be an effective tool for different applications in the health ***,blockchain provides a distributed system along with greater privacy,transparency,and *** this article,we have presented a blockchain-based system that seamlessly integrates testing and vaccination systems,allowing the system to be *** instant verification of any tamper-proof COVID-19 test result has been developed,which will serve as“Test Certificates”.A transparent and efficient vaccination system has also been exhibited and implemented as the“Digital Vaccine Passport”(DVP)*** infection rate-based prioritization will ensure a transparent and fair vaccination process as well as tackle the distribution issue of the limited amount of *** comparative review with other existing works is also discussed,highlighting a clear difference from the existing *** proposed system is distinctive on the basis of prioritization of vaccines and seamless integration of test certificates and vaccine passports,which will aid in controlling the pandemic *** system will also be handy in the case of tackling any future pandemics initially.

关键词： COVID-19 Blockchain Solidity Digital vaccine passport Vaccination

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Study on Recycling Garments Wastage as an Alternative Sizing Material

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Journal of Textile Science and Technology 2022年第1期8卷 15-24页

作者： Moin Uddin jabed Hossen Emon Jonaetul Kibria Niloy Directorate of Technical Education Dhaka Bangladesh Department of Textile Engineering Uttara University Dhaka Bangladesh Department of Wet Processing Engineering Textile Engineering College Zorargonj Chattogram Bangladesh

This paper deals with garments wastage, which could proficiently assess alternative sizing materials than conventional sizing materials. In this research, the synthesized Carboxymethyl Cellulose (CMC) was originated from garments wastages and after that, synthesized CMC and exported CMC were added in sizing recipe for newly sized yarn and conventionally sized yarn respectively. Yarn count, strength, CSP, desizing efficiency and dye absorbency have been evaluated and a comparison has been made among the samples. Less count variation was found in newly sized yarn and a desirable amount of strength & CSP were also acquired in newly sized yarn but it was slightly less than the conventional one. After desizing and dye absorbency test, it has shown a favorable character for further steps like dyeing, printing, etc. These findings convey that synthesized CMC prepared from garments wastage in this study are good candidates for alternative sizing agents.

关键词： Garment Wastages Carboxymethyl Cellulose (CMC) Sizing Strength CSP

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YOLObin: Non-Decomposable Garbage Identification and Classification Based on YOLOv7

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Journal of Computer and Communications 2022年第10期10卷 104-121页

作者： Md. Rakib jabed Md. Shamsuzzaman Department of Computer Science and Engineering Begum Rokey University Rangpur Bangladesh

In order to safeguard the biological framework on which human creatures depend for presence and make society feasible improvement, it is becoming increasingly important to classify garbage. In any case, individuals are not recognizable with the classification strategy, so it is troublesome for individuals to accurately get the classification of each kind of rubbish. A proper waste management system is a primary task in building a smart and healthy city. In arrange to direct individuals to classify garbage accurately, this paper proposes a strategy of rubbish classification and acknowledgment based on YOLOv7 which is a cutting edge real time object detector. Performance of this model is compared along with two other object detectors where Mask-RCNN achieved f-measurement of 85%, YOLOv5 achieved f-measurement of 95.1% and YOLOv7 achieved f-measurement 95.9%. We have used non-decomposable multiclass garbage images which entails messy backgrounds with unwanted images as well. Four classes of non-decomposable garbage data namely chips packet, plastic bottle, polythene and image with multiclass garbage with 1000 images are prepared for our dataset. Our experimental models performed well in classifying garbage images with cluttered backgrounds. We compared our test results to previous studies in which the majority of the models were tested and trained using laboratory images. The test comes about illustrates that the classification framework features a sensible degree of accuracy and the segmentation recognition impact is way better within the case of point-by-point picture, which can proficiently and helpfully total the rubbish classification errand.

关键词： Mask-RCNN YOLOv5 YOLOv7 Garbage Classification Machine Learning

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