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The progress and prospect of assessment measures of uterine cavity function for infertility patients

Global Health Journal 2021年第2期5卷 79-82,F0002页

作者： Luping Zhang Rui ju Xiangyan Ruan Yinmei Dai Husheng Wang Fengyu Jin Jing Jin Muqing Gu Jiaojiao Cheng Yu Yang Xin Xu Thomas Roemer Department of Gynecological Endocrinology Beying Obstetrics and Gynecology HospitalCapital Medical UniversityYaojiayuan Road 251Beijing 100026China Department of Women’s Health University Hospital TuebingenCalwer Strasse 7Tuebingen 72076Germany Department of Obstetrics and Gynecology Evangelishes Klinikiim Koln WeyertdLUniversity of CologneKoln 50931Germany

Objective:To explore the progress and prospect of evaluation methods for infertility ***:From September 2017 to December 2020,199 cases of infertility patients who have accepted mini-hysteroscopy examination in the Department of Gynecological Endocrinology,Beijing Obstetrics and Gynecology Hospital,Capital Medical *** patients who had primary ovary insufficiency,tubal infertility were excluded;patients with hysteroscopy contradiction,such as acute or sub-acute vaginal tract inflammation,endometrium lesion or endometrium carcinoma,severe cardiovascular,liver or kidney insufficiency were excluded.40 patients were excluded and 15 patients lost follow up,144 patients were eventually included in the *** patient’s age,body mass index,infertility etiology,preoperative and postoperative stimulate ovulation cycle,pregnancy state and pregnancy time were *** effect of mini-hysteroscopy on ovulation induction cycle was analyzed in pregnant ***:The average age of 144 patients was 32.10±4.67 years old.96(66.67%)patients were found to have intrauterine abnormalities,while 48(33.33%)patients were found to have normal intrauterine cavity.48 cases of pregnancy,accounting for 33.33%;the median and interquartile ranges[M(q1,q3)]of ovulation induction cycles before and after surgery were respectively[3(0,5)],[2(1,3)],the difference was statistically significant(P<0.05).Among the 48 pregnant patients,32 of them had no structural lesions in hysteroscopy,the ovulation induction cycle of these patients before and after hysteroscopy were respectively[5(0,9)],[1(0,3)],the difference was statistically significant(P<0.05).Conclusion:Uterine cavity evaluation is important for the assessments of *** an advanced diagnosis instrument,mini-hysteroscopy can not only timely detect the intrauterine abnormalities of patients,hut also with great application value in shorten the ovulation cycle in infertility patients and increase the pregnan

关键词： Mini-hysteroscopy Infertility Polycystic ovarian syndrome Endometrium scratch

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石英纤维/KH308复合材料的介电性能

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复合材料学报 2014年第3期31卷 563-568页

作者：陈东居建国郝旭峰上海复合材料科技有限公司上海201112

为研究石英纤维/聚酰亚胺(KH308)复合材料介电性能与纤维体积分数、频率、温度和吸水率之间的关系,通过热压成型法,制备了4种不同纤维体积含量的石英纤维/KH308复合材料,采用高q谐腔法分别测试这4种复合材料在不同状态下的介电常数和介... 详细信息

为研究石英纤维/聚酰亚胺(KH308)复合材料介电性能与纤维体积分数、频率、温度和吸水率之间的关系,通过热压成型法,制备了4种不同纤维体积含量的石英纤维/KH308复合材料,采用高q谐腔法分别测试这4种复合材料在不同状态下的介电常数和介电损耗。结果表明:石英纤维/KH308复合材料的介电常数随着纤维体积分数增加而变大,介电损耗随纤维体积分数变化不大;7~18GHz频率下,复合材料的介电常数和介电损耗基本不随频率变化;25~300℃下,复合材料的介电常数随温度增加变化比较平缓,而介电损耗随温度的增加而降低;复合材料吸水后,介电常数和介电损耗都会增加;复合材料介电常数ε<4,介电损耗tanδ<0.1,能满足导弹天线罩透波材料介电性能的要求。

关键词：石英纤维聚酰亚胺介电性能天线罩透波材料

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JAK2 V617F positive essential thrombocythemia developing in a patient with CD5-chronic lymphocytic leukemia

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Chinese Medical Journal 2012年第11期125卷 2076-2079页

作者： WEI ju WANG Chun qIN You-wen ZHU jun GAO Yang-rong CAI qi YAN Shi-ke Department of Hernatology Shanghai First People＇s Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200080 China Laboratory of Hematology Shanghai First People＇s Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200080 China

Coexistence of chronic lymphocytic leukemia （CLL） and essential thrombocythemia （ET） in a patient is extremely rare, with only 10 cases reported thus far in literature. This paper describes a 94-year-old male having atypical B-CLL with CD5- （CD5-） phenotype and ET. In this patient, we performed interphase fluorescence in situ hybridization （FISH） analysis which revealed 13q14.3 deletion in 31% of B-lymphocyte nuclei and RB1 deletion in 27% of B-lymphocyte nuclei, but not in neutrophils and T-lymphocytes. Furthermore, we identified JAK2 V617F mutation in the peripheral blood nucleated cells and neutrophils, but not in the B- and T-lymphocyte populations. Therefore, it was concluded that the occurrence of CD5- B-CLL and ET in this patient was pathogenically independent.

关键词： essential thrombocythemia chronic lymphocytic leukemia, JAK2 V617F mutation, CD5- fluorescence in situ hybridization

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RegCM3_IAP9L-AGCM对中国跨季度短期气候预测的回报试验研究

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气象学报 2012年第2期70卷 244-252页

作者：鞠丽霞郎咸梅中国科学院大气物理研究所气候变化研究中心北京100029 中国科学院大气物理研究所国际气候与环境科学中心北京100029

将区域气候模式RegCM3与中国科学院大气物理研究所全球大气环流模式IAP9L-AGCM进行单向嵌套,建立嵌套区域气候模式RegCM3_IAP9L-AGCM,并利用该嵌套模式对1982—2001年中国夏季短期气候进行了跨季度集合回报试验。结果表明,RegCM3_IAP9L-... 详细信息

将区域气候模式RegCM3与中国科学院大气物理研究所全球大气环流模式IAP9L-AGCM进行单向嵌套,建立嵌套区域气候模式RegCM3_IAP9L-AGCM,并利用该嵌套模式对1982—2001年中国夏季短期气候进行了跨季度集合回报试验。结果表明,RegCM3_IAP9L-AGCM对高空气候变量(500hPa位势高度场、200和850hPa纬向风场)的回报结果与实况距平相关系数(ACC)基本为正,其回报效果好于单独使用IAP9L-AGCM的结果。除850hPa纬向风场外,其他两个变量场回报与实况正相关的区域基本呈纬向带状分布且通过90%信度检验。在中国大部分地区(除长江下游、东北北部和西北北部外),嵌套区域气候模式回报的降水距平百分率与实况基本为正相关。RegCM3_IAP9L-AGCM和IAP9L-AGCM对中国不同区域的夏季降水回报效果不同,前者对华南降水的回报效果明显好于后者。

关键词： RegCM3 嵌套区域气候模式回报试验跨季度短期气候预测

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Mutation of RET proto-oncogene in Hirschsprung's disease and intestinal neuronal dysplasia

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World Journal of Gastroenterology 2006年第7期12卷 1136-1139页

作者： Jin-Fa Tou Min-ju Li Tao Guan Ji-Cheng Li Xiong-Kai Zhu Zhi-Gang Feng Department Of Pediatric Surgery the Children's Hospital affiliated to the Medical College of Zhejiang University Hangzhou 310003Zhejiang Province China Department of Lymphology Department of Histology and Embryology Zhejiang University Medical College Hangzhou 310031 Zhejiang Province China

AIM： To investigate the genetic relationship between Hirschsprung＇s disease （HD） and intestinal neuronal dysplasia （IND） in Chinese population.METHODS： Peripheral blood samples were obtained from 30 HD patients, 20 IND patients, 18 HD/IND combined patients and 20 normal individuals as control. Genomic DNA was extracted according to standard procedure. Exons 11,13,15,i7 of RET proto-oncogene were amplified by polymerase chain reaction （PCR）. The mutations of RET proto-oncogene were analyzed by single strand conformational polymorphism （SSCP） and sequencing of the positive amplified products was performed.RESULTS： Eight germline sequence variants were detected. In HD patients, 2 missense mutations in exon 11 at nucleotide 15165 G→A （G667S）, 2 frameshifc mutations in exon 13 at nucleotide 18974 （18974insG）, 1 missense mutation in exon 13 at nucleotide 18919 A→G （K756E） and 1 silent mutation in exon 15 at nucleotide 20692 G→A（q916q） were detected. In HD/IND combined patients, 1 missense mutation in exon 11 at nucleotide 15165 G→A and 1 silent mutation in exon 13 at nucleotide 18888 T→G （L745L） were detected. No mutation was found in IND patients and controls.CONCLUSION： Mutation of RET proto-oncogene is involved in the etiopathogenesis of HD. The frequency of REr proto-oncogene mutation is quite different between IND and HD in Chinese population, IND is a distinct clinical entity genetically different from HD.

关键词： RET proto-oncogene Hirschsprung's disease Intestinal neuronal dysplasia

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Some Equivalent Conditions for Block Independence of Reflexive Inner Inverse of Block Matrix

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Journal of Mathematical Research and Exposition 2002年第3期22卷 375-379页

作者：王宜举南京师范大学数学与计算机科学学院

The definition of block independence in generalized inverse of block matrix was introduced in [1]. In this paper, we give some equivalent conditions for two m × n matrices being block independent in reflexive inner i... 详细信息

关键词： Reflexive inner inverse rank block independence.

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优秀散打运动员心脏泵血功能对模拟比赛情景的应答变化特征

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广州体育学院学报 2016年第2期36卷 100-103,107页

作者：王聚龙广州体育学院武术系广东广州510500

采用模拟比赛情景训练的方法,对16名高水平散打运动员运动过程中的心脏泵血功能变化进行研究,探究其应答及变化规律。结果表明:(1)心泵功能:HR和LVET呈相反方向变化;SV、CO、SI、CI变化呈峰形,第二回合达最高,回合间指标存在差异,P<0.05... 详细信息

采用模拟比赛情景训练的方法,对16名高水平散打运动员运动过程中的心脏泵血功能变化进行研究,探究其应答及变化规律。结果表明:(1)心泵功能:HR和LVET呈相反方向变化;SV、CO、SI、CI变化呈峰形,第二回合达最高,回合间指标存在差异,Pq-Z间期逐步减小;回合间指标存在差异,P<0.05;(3)心脏做功:CWI呈逐步上升趋势,回合间呈显著差异,P<0.05;(4)心血管机能:SP、MAP逐步上升;DP、TPR前两回合逐步下降,第三回合上升;C逐步下降。第一、二回合比,SP、DP、TPR存在差异,P<0.05;二、三回合比,MAP、C存在差异,P<0.05。结论:部分心脏泵血功能指标对模拟比赛具有较高的应答性,且呈现特定的规律,这对选拔散打人才,评估散打运动员心脏功能,科学指导散打训练提供了参考。

关键词：散打运动员情景训练心脏泵血功能

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Two new neolignans from Manglietia insignis

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Natural Products and Bioprospecting 2012年第5期2卷 227-230页

作者： Shan-Zhai SHANG ju-Ming YAN Hai-Bo ZHANG Yi-Ming SHI Zhong-Hua GAO Xue DU Yan LI Wei-Lie XIAO Han-Dong SUN State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina University of Chinese Academy of Sciences Beijing 100049China

Two new neolignans,manneoinsigins A(1)and B(2),together with four known lignans,were isolated from the leaves and stems of Manglietia *** new compounds were established on the basis of extensive spectroscopic *** compounds except 2 were tested for their cytotoxic *** 3 showed weak cytotoxic activity against the HL-60 human tumor cell line with the IC50 value of 23.5μM.

关键词： Magnoliaceae Manglietia insignis neolignan cytotoxic activity

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Research progress on the influence of opioids on fetal neurodevelopment during pregnancy

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Life Research 2020年第2期3卷 68-77页

作者： Xia-Lei Li Yue-Han Guo Shu-Ting Wei ju Chen Yi-Bo Wu Department of Clinical Pharmacy School of Pharmaceutical SciencesShandong UniversityJinan 250014China Wuhan mental health center Wuhan 430022China Department of clinical medicine School of Basic MedicineShandong UniversityJinan 250014China Affiliated Hospital of Guangdong Medical University Zhanjiang 524000China Department of Pharmacy Management and Clinical Pharmacy School of PharmacyPeking UniversityBeijing 100191China Health Culture Research Center of Shaanxi Xi'an 712046China

Women usually suffer from chronic pain due to pregnancy or have an increased level of chronic *** view of the definite curative effect of opioids on chronic pain and opioid use disorders,opioids have attracted much attention in the treatment of bone,joint,neuropathic and other chronic pain and opioid use disorders in pregnant *** that the unreasonable use of opioids by pregnant women will lead to risks such as drug accumulation and increased neural sensitivity in the fetus,the correct and reasonable use of opioids is the key to the *** recent years,it has been found that opioids can cross the blood fetal barrier into the fetal circulation,and damage fetal nerve development to varying ***,the studies on the typical diseases such as neonatal neural tube defects and neonatal abstinence syndrome are not ***,this article has clarified the unreasonable use of opioids during pregnancy and its effect on fetal nerve development,and put forward relevant measures in order to provide reference for clinicians/pharmacists in obstetrics and gynecology.

关键词： Pregnant women Unreasonable use of opioids Fetal neurodevelopment Improvement measures

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低温烧结Mg_4Nb_2O_9微波介质陶瓷

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硅酸盐通报 2015年第3期34卷 782-787页

作者：刘长菊苏未安江西理工大学理学院赣州341000

研究了V2O5对Mg4Nb2O9陶瓷的烧结温度、相结构和微波介电性能的影响。结果表明,添加1%~8%的V2O5,能使该陶瓷的烧结温度降低到1000~1050℃而对其微波介电性能的影响很小,材料的主晶相为有序型刚玉结构的Mg4Nb2O9,存在Mg4Nb2O6和Mg5Nb4O1... 详细信息

研究了V2O5对Mg4Nb2O9陶瓷的烧结温度、相结构和微波介电性能的影响。结果表明,添加1%~8%的V2O5,能使该陶瓷的烧结温度降低到1000~1050℃而对其微波介电性能的影响很小,材料的主晶相为有序型刚玉结构的Mg4Nb2O9,存在Mg4Nb2O6和Mg5Nb4O15杂相而没有检测到V2O5的存在。陶瓷的密度对微波介电性能起着决定性作用,介电常数εr与密度成线性关系（在99.99%的置信限内,其相关系数为0.98252）,q·f值与密度的关系较复杂。添加1%的V2O5,将Mg4Nb2O9陶瓷的烧结温度降低到了1050℃,得到了εr=12.72,q·f=151040GHz的优异性能。

关键词：微波介质陶瓷低温烧结Mg4Nb2O9 刚玉型晶体结构助熔剂V2O5

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