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联合应用卡铂与紫杉醇治疗进展性和复发性宫颈癌:英国哥伦比亚癌症中心的治疗经验

世界核心医学期刊文摘（妇产科学分册） 2005年第11期1卷 38-38页

作者： Tinker A.V. Bhagat K. Swenerton K.D. Hoskins P.j. 王颖 Peter MacCallum Cancer Centre St. Andrew' s Place East Melbourne Vic. 3002 Australia

Background. One of the most active chemotherapy combinations in advanced or recurrent cervical cancer is cis-platin-paclitaxel. However, this palliative regimen is associated with significant toxicity. Carboplatin-paclitaxel is thus an attractive option. Methods. Patients with advanced or recurrent carcinoma of the cervix treated with carboplatin-paclitaxel from April 2000 were included in the study. Starting doses of carboplatin-paclitaxel were: AUC 5-6 and 155-175 mg/m2, respectively, repeated every 28 days. Results. Twenty-five women treated with this combination were identified. Twenty-three women (92% ) had prior treatment with pelvic radiotherapy and 14 (56% ) had had concurrent radio-sensitizing cisplatin. There was a 20% PR and a 20% CR rate (10/25). The median progression-free survival for the entire group was 3 months. Responders had a median PFS of 16 months. Fourteen patients (56% ) had died of disease progression. The median overall survival (OS) was 21 months. Common toxicities included: grade 1 or 2 anemia, 68% ; grade 3 or 4 anemia, 32% ; grade 3 or 4 neutropenia, 32% ; and grade 1 or 2 peripheral neuropathy, 24% . ECOG ps did not change significantly while on treatment. Eighty-four percent of treatments were delivered on time, and 96% at full dose. Conclusions. Carboplatinpaclitaxel is an active combination in advanced and recurrent cervical cancer. In this predominantly pre-irradiated group, the combination was deliverable, well tolerated, and the most commonly observed toxicity was anemia.1078. A phase Ⅱ evaluation of flavopiridol as second-line chemotherapy of endometrial carcinoma: A Gynecologic Oncology Group study Grendys jr. E.C./Blessing j.A./Burger R./Hoffman j. E.C. Grendys jr., Florida Gynecologic Oncology, 2780 Cleveland Avenue, Fort Myers, FL 33901, United States -GYNECOL. ONCOL. 2005, 98/2 (249-253) Objective. A phase Ⅱ study was conducted to determine the efficacy of single agent flavopiridol therapy in patients with recurrent or pers

关键词：癌症中心联合方案放疗史毒性反应增敏剂存活期联合用药反应率癌症进展

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激光等离子体不稳定自聚焦细丝可能性的实验研究

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中国激光 1983年第Z1期 500-500页

作者：林尊琪 O.Willi P.T.Rumsby R.G.Evans j.Szechi 中国科学院上海光学精密机械研究所英国卢瑟福-阿普尔顿实验室

作者曾提出冕区激光等离子体中光自聚焦细丝可能是大量的、不稳定的过程。它可能会影响激光的吸收和冕区多种非线性相互作用过程。这里我们首次报告倍频打靶（λ=0.53μm）后向散射ωo时间分辨谱呈现强烈时间和光谱调制的实验结果。调... 详细信息

作者曾提出冕区激光等离子体中光自聚焦细丝可能是大量的、不稳定的过程。它可能会影响激光的吸收和冕区多种非线性相互作用过程。这里我们首次报告倍频打靶（λ=0.53μm）后向散射ωo时间分辨谱呈现强烈时间和光谱调制的实验结果。调制的时间和光谱尺度分别约为10ps和3～5A。当激光靶面功率密度在1012W/cm2到5×1015W/cm2大范围内调整及靶原子序在大范围内变动的条件下都发现明显的调制现象。实验表明,光谱时间调制结构在靶面各取样点的空间相关性是很差的。这可能意

关键词：细丝激光等离子体谐波辐射

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Effects of nitrogen on photosynthetic characteristics of leaves from two different stay-green corn(Zea mays L.) varieties at the grain-filling stage

Effects of nitrogen on photosynthetic characteristics of lea...

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2012年中国作物学会学术年会

作者： G.Li1,Z.-S.Zhang2,H.-Y.Gao2,P.Liu1,3,S.-T.Dong1,3,j.-W.Zhang1,and B.Zhao1 1State Key Laboratory of Crop Biology,College of Agronomy,Shandong Agricultural University,Tai’an 271018,China and 2College of Life Science,Shandong Agricultural University,Tai’an 271018,China.

The effects of nitrogen on the photosynthetic characteristics of two different stay-green corn(Zea mays L.) at the grain-filling stage were *** a stay-green inbred line(Q319) and a non-stay-green inbred line(HZ4) as materials,using fast chlorophyll fluorescence-induction kinetics and 820 nm light-absorption curves,we analyzed the influences of nitrogen supplementation on photosystem I(ps I) and photosystem II(ps II).The results show that nitrogen fertilization has significant effects on promoting the net photosynthetic rate(Pn) in leaves at the grain-filling stage and on single-plant grain yield at the harvest stage(PjIP-Test showed that nitrogen fertilization significantly increased electron donor and acceptor performance in the reaction center of ps II(Pps II reaction center was greater in Q319 than in HZ4,reducing excessive excitation energy production in ps II and significantly improving the coordination between ps II and ps *** the performance of the electron transport chain after the electron acceptor in the ps II reaction center was increased in HZ4,the increase was not substantial enough to improve the coordination between ps II and ps I;therefore,Pn and grain yield were still significantly lower than those of Q319.

关键词： Nitrogen corn stay-green variety photosynthetic characteristics photosystem

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胎儿肺内病灶的产前超声诊断及其结局分析

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中华超声影像学杂志 2008年第7期17卷 612-614页

作者：陈琮瑛李胜利欧阳淑媛刘菊玲文华轩毕静茹姚远杨晓东南方医科大学附属深圳市妇幼保健院超声科深圳518028 南方医科大学附属深圳市妇幼保健院遗传室深圳518028

目的探讨胎儿肺内病灶的声像特征及其临床价值和结局分析。方法常规二维超声扫查评估胎儿双侧肺，发现异常声像时，再用彩色多普勒显示病灶内部血流供应情况并注意观察有无胎儿水肿和其他结构异常声像。在首次超声发现异常后，无胎儿水... 详细信息

目的探讨胎儿肺内病灶的声像特征及其临床价值和结局分析。方法常规二维超声扫查评估胎儿双侧肺，发现异常声像时，再用彩色多普勒显示病灶内部血流供应情况并注意观察有无胎儿水肿和其他结构异常声像。在首次超声发现异常后，无胎儿水肿声像表现者，每隔4～6周后复查。结果40例首次超声发现的肺内异常病灶中表现为强回声者21例，囊实性混合回声者15例，囊性者4例。8例产前超声提示为隔离肺，12例超声提示为肺囊腺瘤，其余20例未予以具体病理诊断提示。17例追踪复查显示病灶稳定或缩小或消失，新生儿结局良好；17例合并胎儿水肿或包块最大直径〉5．0cm及纵隔移位，患者及家属要求终止妊娠。结论产前彩色多普勒超声可发现胎儿肺内病灶，鉴别其病理性质及监测其发展变化，胎儿单纯肺内异常病灶、无胎儿水肿和纵隔移位且病灶稳定或缩小者结局良好，常规产前超声对发现胎儿肺内病灶和评估其预后有重要价值。

关键词：超声检查产前肺疾病支气管肺隔离症囊腺瘤样畸形肺先天性

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家族性阿尔茨海默病:脑脊液Aβ_(42)水平先于认知功能下降

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世界核心医学期刊文摘（神经病学分册） 2005年第12期1卷 54-54页

作者： Moonis M. Swearer j.M. Dayaw M.P.E. D.A. Pollen 周永 r. Department of Neurology University of Massachusetts Medical School 55 Lake Ave. N. Worcester MA 01655 United States

CSF amyloid β-peptide 42 (Aβ42) levels in presymptomatic subjects with pathogenic mutations in the ps1 gene are significantly lower than in an age-matched control group. Consequently, in these subjects, there is a window of opportunity estimated as at least 4 to 12 years to evaluate the ability of any putative prophylactic therapy to decrease, arrest, or reverse abnormalities in Aβ42 metabolism many years before clinical symptoms of Alzheimer disease are otherwise likely to occur.

关键词：认知功能淀粉样β肽阿尔茨海默病基因病预防性治疗前几

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一种新型皮秒同步扫描变像管

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高速摄影与光子学 1989年第1期18卷 11-16页

作者：牛憨笨张焕文王贤华杨勤劳刘月平王云程任永安周军兰中国科学院西安光学精密机械研究所

本文描述了一种新型皮秒同步扫描变像管的设计特点及实验结果。其静态空间分辨率为50lp/mm,时间分辨率为1.

关键词：变象管同步扫描皮秒变象管

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血友病关节的X线片评分:采用示例图集提高观察者之间及观察者本身的信度及一致性

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国际医学放射学杂志 2016年第4期 464-464页

作者： W.Foppen I.C.van der Schaaf F.j.A.Beek H.M.Verkooijen K.Fischer 钟怡 Department of Radiology University Medical Center Utrecht

摘要目的广泛应用于各种关节病的X线片Pettersson评分(ps)也应用于血友病关节昂贵治疗的疗效评估。本研究旨在评价和提高ps评分的观察者之间及观察者本身的信度及一致性。方法由3名观察者分别给10例血友病关节病人双侧肘、膝、踝关节的... 详细信息

摘要目的广泛应用于各种关节病的X线片Pettersson评分(ps)也应用于血友病关节昂贵治疗的疗效评估。本研究旨在评价和提高ps评分的观察者之间及观察者本身的信度及一致性。方法由3名观察者分别给10例血友病关节病人双侧肘、膝、踝关节的X线片各2组(共120个关节)进行ps

关键词：血友病病人 ps 凝血障碍关节运动器官信度图集

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在克隆病的动物模型中磁化传递有助于检测肠纤维化

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国际医学放射学杂志 2011年第3期 286-286页

作者： j.Adler S.D.Swanson P.Schmiedlin-Ren P.D.R.Higgins C.P.Golembeski A.D.Polydorides 焦慧 Department of Pediatrics Division of GastroenterologyUniversity of Michigan Medical Center

目的在Crohn病的小鼠模型中研究磁化传递对识别和定量分析肠纤维化的作用。材料与方法本项研究经过大学委员会和动物关爱委员会通过(UCUCA08592)。浆膜

关键词：肠纤维化 PG ps 磁化传递率小鼠小家鼠

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Fungal diversity notes 1512–1610: taxonomic and phylogenetic contributions on genera and species of fungal taxa

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Fungal Diversity 2022年第6期117卷 1-272页

作者： Ruvishika S.jayawardena Kevin D.Hyde Song Wang Ya‑Ru Sun Nakarin Suwannarach Phongeun Sysouphanthong Mohamed A.Abdel‑Wahab Faten A.Abdel‑Aziz Pranami D.Abeywickrama Vanessa P.Abreu Alireza Armand AndréAptroot Dan‑Feng Bao Dominik Begerow jean‑Michel Bellanger jadson D.P.Bezerra Digvijayini Bundhun Mark S.Calabon Ting Cao Taimy Cantillo joão LVRCarvalho Napalai Chaiwan Che‑Chih Chen Régis Courtecuisse Bao‑Kai Cui Ulrike Damm Cvetomir M.Denchev Teodor T.Denchev Chun Y.Deng Bandarupalli Devadatha Nimali Ide Silva Lidiane Ados Santos Nawal K.Dubey Sylvain Dumez Himashi SFerdinandez André L.Firmino Yusufon Gaforov Achala j.Gajanayake Deecksha Gomdola Sugantha Gunaseelan Shucheng‑He Zin H.Htet Malarvizhi Kaliyaperumal Martin Kemler Kezhocuyi Kezo Nuwan DKularathnage Marco Leonardi ji‑Peng Li Chunfang Liao Shun Liu Michael Loizides Thatsanee Luangharn jian Ma Hugo Madrid S.Mahadevakumar Sajeewa S.N.Maharachchikumbura Dimuthu S.Manamgoda María P.Martín Niranjan Mekala Pierre‑Arthur Moreau Yan‑Hong Mu Pasouvang Pahoua Dhandevi Pem Olinto L.Pereira Wiphawanee Phonrob Chayanard Phukhamsakda Mubashar Raza Guang‑Cong Ren Andrea C.Rinaldi Walter Rossi Binu C.Samarakoon Milan CSamarakoon Vemuri V.Sarma Indunil C.Senanayake Archana Singh Maria F.Souza Cristina M.Souza‑Motta Adriano A.Spielmann Wenxin Su Xia Tang XingGuo Tian Kasun M.Thambugala Naritsada Thongklang Danushka S.Tennakoon Nopparat Wannathes DingPeng Wei Stéphane Welti Subodini N.Wijesinghe Hongde Yang Yunhui Yang Hai‑Sheng Yuan Huang Zhang jingyi Zhang Abhaya Balasuriya Chitrabhanu SBhunjun Timur S.Bulgakov Lei Cai Erio Camporesi Putarak Chomnunti Y.S.Deepika Mingkwan Doilom Wei‑jun Duan Shi‑Ling Han Naruemon Huanraluek EBGareth jones NLakshmidevi Yu Li Saisamorn Lumyong Zong‑Long Luo Surapong Khuna jaturong Kumla Ishara S.Manawasinghe Ausana Mapook Wilawan Punyaboon Saowaluck Tibpromma Yong‑Zhong Lu jiYe Yan Yong Wang Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Innovative Institute for Plant Health Zhongkai University of Agriculture and EngineeringGuangzhou 510225P.R.China Department of Plant Pathology College of AgricultureGuizhou UniversityGuiyang 550025GuizhouChina Research Center of Microbial Diversity and Sustainable Utilization Chiang Mai UniversityChiang Mai 50200Thailand Department of Biology Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Biotechnology and Ecology Institute Ministry of Agriculture and ForestryP.O.Box:811Vientiane CapitalLao PDR Department of Botany and Microbiology Faculty of ScienceSohag UniversitySohag 82524Egypt Beijing Key Laboratory of Environment-Friendly Management on Fruit Diseases and Pests in North China Institute of Plant ProtectionBeijing Academy of Agriculture and Forestry SciencesBeijing 100097China Departamento de Fitopatologia Universidade Federal de ViçosaViçosaMinas GeraisBrazil Laboratório de Botânica/Liquenologia Instituto de BiociênciasUniversidade Federal de Mato Grosso do SulAvenida Costa e Silva S/NBairro UniversitárioCampo GrandeMato Grosso do Sul CEP 79070-900Brazil College of Agriculture and Biological Sciences Dali UniversityDali 671003YunnanChina Department of Entomology and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Institute of Plant Science and Microbiology Universität HamburgOrganismic Botany and MycologyOhnhorststr.1822609 HamburgGermany CEFE CNRSUniv.MontpellierEPHEIRDINSERM1919Route de Mende34293 Montpellier Cedex 5France Setor de Micologia Departamento de Biociências e TecnologiaInstituto de Patologia Tropical e Saúde PúblicaUniversidade Federal de GoiásRua 235S/NSetor UniversitárioGoiâniaGO CEP:74605-050Brazil Division of Biological Sciences College of Arts and SciencesUniversity of the Philippines Visayas5023 MiagaoIloiloPhilippines CA

This article is the 14th in the Fungal Diversity Notes series,wherein we report 98 taxa distributed in two phyla,seven classes,26 orders and 50 families which are described and *** in this study were collected from Australia,Brazil,Burkina Faso,Chile,China,Cyprus,Egypt,France,French Guiana,India,Indonesia,Italy,Laos,Mexico,Russia,Sri Lanka,Thailand,and *** are 59 new taxa,39 new hosts and new geographical distributions with one new *** 59 new species comprise Angustimassarina kunmingense,Asterina lopi,Asterina brigadeirensis,Bartalinia bidenticola,Bartalinia caryotae,Buellia pruinocalcarea,Coltricia insularis,Colletotrichum fexuosum,Colletotrichum thasutense,Coniochaeta caraganae,Coniothyrium yuccicola,Dematipyriforma aquatic,Dematipyriforma globispora,Dematipyriforma nilotica,Distoseptispora bambusicola,Fulvifomes jawadhuvensis,Fulvifomes malaiyanurensis,Fulvifomes thiruvannamalaiensis,Fusarium purpurea,Gerronema atrovirens,Gerronema favum,Gerronema keralense,Gerronema kuruvense,Grammothele taiwanensis,Hongkongmyces changchunensis,Hypoxylon inaequale,Kirschsteiniothelia acutisporum,Kirschsteiniothelia crustaceum,Kirschsteiniothelia extensum,Kirschsteiniothelia septemseptatum,Kirschsteiniothelia spatiosum,Lecanora immersocalcarea,Lepiota subthailandica,Lindgomyces guizhouensis,Marthe asmius pallidoaurantiacus,Marasmius tangerinus,Neovaginatispora mangiferae,Pararamichloridium aquisubtropicum,Pestalotiopsis piraubensis,Phacidium chinaum,Phaeoisaria goiasensis,Phaeoseptum thailandicum,Pleurothecium aquisubtropicum,pseudocercospora vernoniae,Pyrenophora verruculosa,Rhachomyces cruralis,Rhachomyces hyperommae,Rhachomyces magrinii,Rhachomyces platyprosophi,Rhizomarasmius cunninghamietorum,Skeletocutis cangshanensis,Skeletocutis subchrysella,Sporisorium anadelphiae-leptocomae,Tetraploa dashaoensis,Tomentella exiguelata,Tomentella fuscoaraneosa,Tricholomopsis lechatii,Vaginatispora favispora and Wetmoreana *** new combin

关键词： 59 New taxa 39 New records Ascomycota Basidiomycota Dothideomycetes Lecanoromycetes Leotiomycetes Sordariomycetes Ustilaginomycotina

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