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苏格兰地区心绞痛的患病率、发病率、初级医疗负担和药物治疗:一项关于年龄、性别和社会经济学差异的人群研究

世界核心医学期刊文摘（心脏病学分册） 2006年第12期2卷 40-41页

作者： Murphy N.F. simpson C.R. MacIntyre K. j.j.V. McMurray 徐永城 Department of Cardiology Western Infirmary Glasgow G11 6NT United Kingdom Prof.

Objective: To examine the epidemiology, primary care burden and treatment of angina in Scotland. Design: Cross-sectional data from primary care practices participating in the Scottish continuous morbidity recording scheme between 1 April 2001 and 31 March 2002. Setting: 55 primary care practices(362 155 patients). Participants: 9508 patients with angina. Results: The prevalence of angina in Scotland was 28/1000 in men and 25/1000 in women(p< 0.05) and increased with age. The prevalence of angina also increased with increasing socioeconomic deprivation from 18/1000 in the least de-prived category to 31/1000 in the most deprived group(p< 0.001 for trend). The incidence of angina was higher in men(1.8/1000) than in women(1.4/1000)(p=0.004) and increased with increasing age and socioeconomic deprivation. Socioeconomically deprived patients(0.48 contacts/patient among the most deprived) were less likely than affluent patients(0.58 contacts/patient among the least deprived) to see their general practitioner on an ongoing basis (p=0.006 for trend). Among men, 52%were prescribed βblockers, 44%calcium channel blockers, 72%aspirin, 54%statins and 36%angiotensin converting enzyme inhibitors or angiotensin receptor blockers. The corresponding prescription rates for women were 46%(p< 0.001), 41%(p=0.02), 69%(p< 0.001), 45%(p< 0.001) and 30%(p< 0.001). Among patients< 75 years old 52%were prescribed a βblocker and 58%a statin. The corresponding figures for patients ≥75 years were 42%(p< 0.001) and 31%(p< 0.001). Conclusions: Angina is a common condition, more so in men than in women. Socioeconomically deprived patients are more likely to have angina but are less likely to consult their general practitioner. Guideline-recommended treatments for angina are underused in women and older patients. These suboptimal practice patterns, which are worst in older women, are of particular concern, as in Scotland more women(and particularly older women) than men have angina.

关键词：心绞痛冠心病患病率发病率苏格兰

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Two Crimes, Two Punishments

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大学英语 1995年第12期 32-32页

作者： O.j.simpson Susan Smith RICK BRAGG

On different sides of the country, in different worlds of power and influence, Susan V. Smith and O.j. simpson are accused of murder by unspeakable means. The difference is in the price the criminal-justice system wil... 详细信息

关键词： In Two Crimes Two Punishments

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应用微气象学方法测定尿素的氨挥发损失

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上海农业学报 1987年第4期 47-56页

作者：奚振邦施秀珠黄伟祥姚政 E.Humphereys j.R.Freney j.R.simpson(CSIRO) 上海市农业科学院土壤肥料研究所上海市农业科学院土壤肥料研究所上海市农业科学院土壤肥料研究所上海市农业科学院土壤肥料研究所澳大利亚联邦科学与工业研究组织澳大利亚联邦科学与工业研究组织澳大利亚联邦科学与工业研究组织上海上海上海上海

在上海郊区首次应用微气象学方法测定了尿素施于栽培甘蓝田间后的氨挥发损失。尿素用量225公斤/公顷。尿素分100%表施与尿素70%混施于土层（另30%表施）两处理。连续11天累计的氨态 N 挥发损失显著,分别为39.2公斤/公顷和25.0公斤/公顷... 详细信息

在上海郊区首次应用微气象学方法测定了尿素施于栽培甘蓝田间后的氨挥发损失。尿素用量225公斤/公顷。尿素分100%表施与尿素70%混施于土层（另30%表施）两处理。连续11天累计的氨态 N 挥发损失显著,分别为39.2公斤/公顷和25.0公斤/公顷,或尿素施用量的17.4%和11.1%。其损失量大小,与土壤水分,土壤 pH 和尿素施用深度等密切相关。试验期间,0—5cm土壤中的尿素浓度随试验时间延长而减少;氨态 N（NH4++ NH3）则随试验时间延长而增加。研究结果表明,把大部分尿素混施于耕层的方法,将能明显提高肥效。

关键词：微气象学方法氨挥发尿素

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土壤中的反硝化作用和缔合氮的转化

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河南大学学报(自然科学版) 1977年 73-79页

作者： George Stanford ,j.O.Legg ,Stanislaw Dzienia ,E.C.simpson,jr. ,王庭梧 ,王德甫

目前普遍认为,由于土壤中的生物反硝化作用,导致差不多所有的硝酸根都转变成了氮气和一氧化二氮（威勒与德威奇1954,诺密克1956,布伦纳与肖氏1958,卡迪与巴塞洛缪1960,库珀与史密斯1963）。相反,麦克雷等人（1968）发现,施加于四种菲律... 详细信息

目前普遍认为,由于土壤中的生物反硝化作用,导致差不多所有的硝酸根都转变成了氮气和一氧化二氮（威勒与德威奇1954,诺密克1956,布伦纳与肖氏1958,卡迪与巴塞洛缪1960,库珀与史密斯1963）。相反,麦克雷等人（1968）发现,施加于四种菲律宾洪积土壤中的K15NO3,6星期后有4.5～39％转变成了有机N。在使用15NO3-的研究中,以往都没有检测到15N示踪的NH1+（威勒和德威奇1954;诺密克1956;布伦纳与肖氏1958;麦克雷等人1968）。

关键词：异化作用蒂姆克兰分解代谢反硝化作用硝酸根气态产物反硝化微生物右旋糖己糖葡萄糖 NH

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Pediatric obesity prevention:From na?ve examination of energy imbalance towards strategies that influence the competition for nutrient resources among tissues

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World journal of Clinical Pediatrics 2015年第4期4卷 50-54页

作者： Lynae j Hanks Tina simpson Kenneth McCormick Krista Casazza Department of Kinesiology University of Montevallo Division of General Pediatrics and Adolescent Medicine Department of PediatricsUniversity of Alabama at Birmingham Division of Endocrinology Department of PediatricsUniversity of Alabama at Birmingham

Current pediatric obesity interventions have collectively yielded relatively unsuccessful results. In this Field of Vision, we present plausible physiologic underpinnings fostering ineffectiveness of conventional strategies grounded in requisite induction of negative energy imbalance. Moreover, such recommendations exacerbate the underlying metabolic dysfunction by further limiting metabolic fuel availability, lowering energy expenditure, and increasing hunger(recapitulating the starvation response amid apparent nutritional adequacy) which precede and promote obesity during growth and development. The qualitative aspects of musculoskeletal system(i.e., endocrine response, muscle functional capacity) are likely to improve metabolic function and increase nutrient delivery and utilization. An intricate and complex system including multiple feedback mechanisms operates to homeostatically regulate energy balance and support optimal body composition trajectories and metabolic health, during growth and development. Thus, ignoring the interdependencies of regulatory growth processes initiates a nuanced understanding of energy regulation and thus misguided attempts at preventive strategies. Importantly, these gains are not dependent upon weight-loss, rather we suggest can be achieved through resistance training. Collectively, optimizing musculoskeletal health via resistance training elicits augmentation of competitive capacity across systems. Further, substantial gains can be achieved in skeletal muscle mass, strength, and functional capacity through resistance training in a relatively short period of time.

关键词： Childhood obesity Metabolic control Energy balance Resistance training Effective intervention strategies Weight loss Musculoskeletal health

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糖蛋白Ⅱb/Ⅲa抑制剂相关性血小板减少症:临床预测指标及其对预后的影响

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世界核心医学期刊文摘（心脏病学分册） 2005年第3期1卷 23-24页

作者： George B.j. Eckart R.E. Shry E.A. simpson D.E. 高登峰 Department of Internal Medicine Brooke Army Medical Center 3851 Roger Brooke Drive San Antonio TX 78234-6200 United States Dr.

Glycoprotein Ⅱb/Ⅲa inhibitors are used as an adjunct to antiplatelet therapy in percutaneous coronary intervention to reduce postprocedural enzyme elevations. Previous studies have shown a risk for thrombocytopenia that is associated with these agents. We sought to evaluate the incidence and outcomes of glycoprotein Ⅲb/Ⅲa inhibitor-associated thrombocytopenia in an unselected series of patients undergoing percutaneous coronary intervention. We reviewed 984 interventions performed on 908 subjects over a specific time period. Glycoprotein Ⅲb/Ⅳa inhibitors were used in 58.8%of cases. Their use increased from 38 to 82%during the study period(p 0.05). The occurrence of thrombocytopenia was not associated with increased in-hospitalmortality, 1-yearmortality,myocardial infarction or revascularization, but was associated with a hospital stay twice as long as in those patients without thrombocytopenia(5.6±11.3 vs. 2.1±2.2 days, p< 0.001). Of the 5.4%of patients who developed thrombocytopenia, only 2 patients(7.1%) required platelet or blood cell transfusion.

关键词：临床预测介入治疗前血小板年死亡率酶活性

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Intestinal heme absorption in hemochromatosis gene knock-out mice

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World journal of Hematology 2017年第1期6卷 17-23页

作者： Abas H Laftah Robert j.simpson Gladys O Latunde-Dada Vascular Sciences NHLIImperial Centre for Translational and Experimental MedicineImperial College London Faculty of Life Sciences and Medicine Division of Diabetes and Nutritional SciencesKing’s College London

AIM To investigat the influence of hemochromatosis gene(Hfe) mutation on ^(59)Fe labelled duodenal heme absorption in *** Heme absorption was measured in Hfe wild type and Hfe^((-/-)) mice by the duodenal tied loop and by oral gavage methods. The m RNA expression of heme oxygenase(HO-1), Abcg2 and Flvcr1 genes and levels were determined by quantitative polymerase chain *** Heme absorption was significantly increased in homozygous Hfe^((-/-)) mice despite significant hepatic and splenic iron overload. While duodenal HO-1 mRNA was highly expressed in the wild type and Hfe^((-/-)) heme-treated group following 24 h heme administration, Flvcr1 a mRNA decreased. However, Abcg2 mRNA expression levels in duodenum remained unchanged. CONCLUSION Heme absorption was enhanced in Hfe^((-/-)) mice from both duodenal tied-loop segments and by oral gavage methods. HO-1 m RNA levels were enhanced in mice duodenum after 24 h of heme feeding and may account for enhanced heme absorption in Hfe^((-/-)) mice. Implications for dietary recommendations on heme intake by Hfe subjects to modulate iron loading are important clinical considerations.

关键词： Hemochromatosis gene Heme Gavage Iron Absorption

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黄淮海地区石灰性稻田土壤上不同混施方法下氮肥的去向和增产效果

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土壤 1988年第3期 121-125页

作者：朱兆良,张绍林,陈德立,蔡贵信,徐银华,j.R.simpson,j.R.Freney,A.V.jackson 中国科学院南京土壤研究所中国科学院南京土壤研究所中国科学院南京土壤研究所中国科学院南京土壤研究所中国科学院南京土壤研究所 Division of Plant Industry CSIRO Australia Division of Plant Industry CSIRO Australia Division of Environmental Mechanics CSIRO Australia

迄今,关于黄淮海地区石灰性稻田土壤上氮肥去向的研究极少。仅见的一个田间微区试验是有关氮肥表施作基肥的,而在生产中却多采用混施的方法。此外,盆栽试验表明,无水层混施能减少氮素损失。因此,有必要在本区稻田土壤上,采用田间微区的... 详细信息

迄今,关于黄淮海地区石灰性稻田土壤上氮肥去向的研究极少。仅见的一个田间微区试验是有关氮肥表施作基肥的,而在生产中却多采用混施的方法。此外,盆栽试验表明,无水层混施能减少氮素损失。因此,有必要在本区稻田土壤上,采用田间微区的方法,进一步明确氮肥混施作基肥时氮素的去向,以及无水层混施在降低氮素损失、提高氮肥增产效果

关键词：稻田土壤水稻土田面水黄淮海地区混施石灰性增产效果增产效益经济效果水稻产量供氮量水层

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出生前被诊断为先天性心脏病的早产儿的转归

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世界核心医学期刊文摘（儿科学分册） 2006年第8期2卷 40-41页

作者： Andrews R. E. simpson j. M. Sharland G. K. 王一飞(译) - j. PEDIATR. 2006 148/2(213 -216) 不详

Objective:To determine outcome of delivery before 36 weeks gestation in babie s diagnosed antenatally with serious congenital heart disease(CHD).Study desig n:A retrospective database review at 2 tertiary care fetal cardiology *** of neonatal course and outcome were obtained for those antenatally diagn osed with serious CHD who were live born before 36 weeks ***:Bet ween january 1998 and December 2002,9918 women were referred for fetal echocard *** CHD was diagnosed in 1191 fetuses(12%),of which 46(4%)de livered *** gestation was 33(range 24-35)weeks,and median bi rth weight 1.56(0.50-3.59)***/karyotypic anomalies occurred in 23(50%).Twenty-six babies(57%)underwent neonatal surgery:16 a cardiac pr ocedure,5 a general surgical procedure,and 5 *** died during or after operation(31%).Two babies underwent interventional heart catheterization;bot h *** overall mortality rate was 72%.Extracardiac/karyotypic anomalies i ncreased the relative risk of death by a factor of *** hospital stay for those surviving to initial discharge was 46(2-137)***:There is a very high morbidity and mortality rate in this group,particularly for those with extracardiac/karyotypic *** should be reflected in decisions ov er elective preterm delivery and when counseling parents.

关键词：先天性心脏病出生前早产儿诊断转归平均出生体重胎儿心脏病心脏超声检查回顾性分析新生儿期

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National preparedness training and exercises for Ebola cases in the United Kingdom

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World journal of Clinical Infectious Diseases 2016年第1期6卷 1-5页

作者： Andrew D Black Hilary j Moulsdale Mark R Evans john L simpson Emergency Response Department Public Health England

In response to the outbreak of Ebola Virus Disease in West Africa, the Emergency Response Department of Public Health England produced a series of training and exercising materials to help prepare health and partner organisations in England and other jurisdictions in the United Kingdom deal with a possible case of Ebola in the United Kingdom. They were produced with input from health(NHS England, Health Protection Scotland, Public Health Wales) and other partner organisations. The exercising materials have been used by colleagues working in national and local level organisations in the United Kingdom and other countries in the European Union. Presented here is a description of these training and exercising materials and how they were delivered to the end user.

关键词： Public health England Exercises Training Ebola Preparedness

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