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Early cisternal fibrinolysis is more effective than rescue spasmolysis for the prevention of delayed infarction after subarachnoid haemorrhage

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Stroke & Vascular Neurology 2022年第2期7卷 108-113页

作者： Roland Roelz Christian Scheiwe j.rgen Grauvogel Istvan Csok Volker Arnd Coenen j.rgen beck Peter C Reinacher Department of Neurosurgery Medical Center-University of FreiburgFreiburgGermany Department of Stereotactic and Functional Neurosurgery Medical Center-University of FreiburgFaculty of MedicineFreiburgGermany Fraunhofer Institute for Laser Technology(ILT) AachenGermany

Background To compare the efficacy of two different concepts of cisternal therapy—PREVENTIVE fibrinolysis plus on-demand spasmolysis versus RESCUE spasmolysis—for the prevention of cerebral vasospasm(CVS)and delayed cerebral infarction(DCI)in patients with aneurysmal subarachnoid haemorrhage(aSAH).Methods Retrospective analysis of 84 aSAH patients selected for cisternal therapy for DCI prevention.66 high-risk patients received PREVENTIVE cisternal therapy to enhance blood *** stereotactic catheter ventriculocisternostomy(STX-VCS)or intraoperative placement of a cisterno-ventriculostomy catheter(CVC),followed by fibrinolytic cisternal lavage using urokinase was *** case of vasospasm,nimodipine was applied intrathecally.22 low-risk patients who developed CVS against expectations were selected for STX-VCS as RESCUE intervention for cisternal spasmolysis with *** of DCI and mean flow velocities of daily transcranial Doppler(TCD)ultrasonographies were *** Despite a higher prespecified DCI risk,patients selected for PREVENTIVE intervention primarily aiming at blood clearance had a lower DCI rate compared with patients selected for intrathecal spasmolysis as a RESCUE therapy(11.3%vs 18.2%).After intrathecal treatment onset,CVS(TCD>160 cm/s)occurred in 45%of patients with PREVENTIVE and 77%of patients with RESCUE therapy(p=0.013).A stronger response of CVS to intrathecal nimodipine was observed in patients with PREVENTIVE intervention as the mean CVS duration after start of intrathecal nimodipine was 3.2 days compared with 5.8 days in patients with RESCUE therapy(p=0.026).Conclusions PREVENTIVE cisternal therapy directed at blood clearance is more effective for the prevention of CVS and delayed infarction compared with cisternal RESCUE spasmolysis.

关键词： prevention spasmolysis infarction

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A simple model for reconstructing geomagnetic field intensity with (10)~Be production rate and its application in Loess studies

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Science China Earth Sciences 2008年第6期51卷 855-861页

作者： j. Warren beck NSF-AMS Laboratory University of Arizona

A simple model for reconstructing the paleomagnetic field intensity with (10)~Be production rate was used for the first time in Loess (10)~Be studies of Luochuan profile. Using the LGM (Last Glacial Maxmium) method, the climatic effects and geomagnetic modulation effects on loess (10)~Be was separated and in turn the 80 ka geomagnetic excursion sequence reconstructed, of which the globally remarkable geomagnetic excursion events such as the Laschamp (42 ka), Mono Lake (32 ka) during the Last Glacial period were revealed and the paleo-geomagnetic intensity curve from Loess (10)~Be over the past 80 ka was quantitatively reconstructed. The reconstructed paleo-intensity fits well with the paleo-intensity curves (SINT200 and NAPIS75), which indicates the significance of global criterion of the (10)~Be paleo- intensity curve and the future direction of loess (10)~Be tracing studies. Results show the irregular vari-ability of the East Asian monsoon precipitation in Loess Plateau is the main cause that has resulted in the ambiguity of the geomagnetic modulation of the (10)~Be record in the loess, and the intrinsic source component of the loess (10)~Be and inherited fraction of magnetic susceptibility (SUS) are characterized by the 'quasi-homogeneous distribution' manner.

关键词： (10)~Be LGM geomagnetic excursion paleointensity quasi-homogeneous distribution

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Crystal Growth of Calcite at Conditions of Gas Processing in Solvent Mixtures of Monoethylene Glycol and Water

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Transactions of Tianjin University 2013年第2期19卷 79-85页

作者： beck R Nergaard M Andreassen j P Department of Chemical Engineering NTNU7491 TrondheimNorway Institute for Energy Technology (IFE) Box 402027 KjellerNorway

Growth kinetics of the most stable polymorph of calcium carbonate,calcite,has been studied in seeded stirred batch experiments in MEG-water solutions at 40 ℃ and 70 ℃,conditions relevant for the processing of natural *** was found that MEG changes the growth order from two in pure water to one in solvent mixtures of MEG and *** parabolic growth (growth order is equal to two),it could be shown that MEG decreases the growth rate constant for calcite from 0.52 nm/s to 0.11 nm/s (70 ℃) when the MEG-content is increased from 0 wt% MEG to 65 wt% *** the temperature from 70 ℃ to 40 ℃ has a similar effect on the growth rate constant as raising the level of MEG to 65 wt%.

关键词： crystallization crystal growth kinetics calcium carbonate calcite solvent mixtures monoethylene glycol (MEG)

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Interactive map reports summarizing bivariate geographic data

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Visual Informatics 2019年第1期3卷 27-37页

作者： Shahid Latif Fabian beck University of Duisburg–Essen paluno–The Ruhr Institute of Software TechnologyGermany

Bivariate map visualizations use different encodings to visualize two variables but comparison across multiple encodings is *** to a univariate visualization,it is significantly harder to read regional differences and spot geographical *** targeting inexperienced users of visualizations,we advocate the use of natural language text for augmenting map visualizations and understanding the relationship between two geo-statistical *** propose an approach that selects interesting findings from data analysis,generates a respective text and visualization,and integrates both into a single *** generated reports interactively link the visualization with the textual *** can get additional explanations and have the ability to compare different *** text generation process is flexible and adapts to various geographical and contextual settings based on small sets of *** showcase this flexibility through a number of application examples.

关键词： Geographic visualization Natural language generation Interactive documents

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Monitoring permeable paver runoff with an open-innovation geospatial sensor network

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International journal of Digital Earth 2016年第1期9卷 30-46页

作者： Andrew j.Rettig Sumit Khanna Richard A.beck Quinn Wojcik Carmen A.McCane Department of Geography University of CincinnatiCincinnatiOHUSA College of Engineering and Computer Science University of Tennessee at ChattanoogaChattanoogaTNUSA

Sensor networks are an essential tool for environmental *** scientists and engineers are beginning to utilize these new methods and devices in their fieldwork,they need to be actively involved in the future of sensor-networking *** sensor network innovation is important for improved standardization,affordability,and *** article uses a storm water case study to outline an end-to-end open-innovation sensor *** innovation by scientists,engineers,and entities is the collaborative process of creating value for this project in permeable paver runoff data and advances within sensor *** article focuses on the technical implementation of the near–real-time location and temporally aware sensor *** are streamed in near–real-time with subliter precision to the cloud using common off-the-shelf *** sensors use Maxim’s 1-wire™protocol,and the unique digital serial numbers confirm the *** data retrieved compare residence times within the permeable paver catchment basins and the control *** network advances are made by bridging the gap between sensor protocols and communication *** advances enable the development of open-source representational state transfer web *** successful implementation serves as an example for others to study and expand upon for a variety of monitoring solutions.

关键词： sensor networks Internet of things open geospatial consortium open innovation permeable pavers

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The relationship of high-intensity cross-training with arterial stiffness

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journal of Sport and Health Science 2019年第4期8卷 370-375页

作者： jamie F.Burr jenny L.beck john j.Durocher Department of Human Health and Nutritional Sciences University of GuelphGuelphON NIG 2W1Canada Applied Human Sciences University of Prince Edward IslandCharlottetownPE CIA 4P3Canada Department of Biological Sciences Michigan Technological UniversityHoughtonMI 49931USA

Background'.Central arterial stiffness is a cardiovascular risk factor that can be readily affected through engagement in physical exercise training,with resistance and aerobic exercise having disparate *** the growing popularity of high-intensity cross-training(HICT),little is currently known about the effects of this mixed modality exercise stimulus on arterial ***,the purpose of this study was to characterize the arterial stiffness of habitual HICT participants *** active and sedentary controls using a cross-sectional ***'.A total of 30 participants were recruited:10 middle-aged long-term participants of HICT(CrossFit)and 20 age,sex,and height matched controls(10 recreationally active,10 sedentary).Central and peripheral pulse wave velocities were measured for the carotid-femoral and femoral-dorsalis pedis arterial *** fitness(maximal oxygen uptake,VChmax)was measured and typical exercise participation rates were self-reported for each ***'.HICT participants manifested central pulse wave velocity(PWV)(5.3±1.0 m/s,mean±SD)and VChmax(43±6 mL/kg/min)values nearly identical to active *** active groups had significantly better values than sedentary controls(7.1±1.0 m/s,p≤0.001;and 32±7 mL/kg/min,p=0.01).No differences were observed in peripheral PWV between ***'.Habitual participation in HICT exercise was not associated with increased central nor peripheral arterial ***-term HICT participants presented with similar fitness and arterial stiffness as compared with participants who practiced traditional aerobic *** to sedentary living,HICT may offer musculoskeletal and cardiovascular health benefits without negatively impacting arterial stiffness.

关键词： Circuit training CrossFit Pulse wave velocity Resistance exercise Vascular Weight training

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Desingularized boundary integral equations and their applications in wave dynamics and wave-body interaction problems

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journal of Ocean Engineering and Science 2016年第1期1卷 11-29页

作者： Yusong Cao Robert F.beck C-Z Marine Technology LLCHoustonTXUSA Department of Naval Architecture and Marine Engineering The University of MichiganAnn ArborMIUSA

Over the past 30 years or so,desingularized boundary integral equations(DBIEs)have been used to study water wave dynamics and body motion *** the potential flow modeling,unlike conventional boundary integral methods,a DBIE separates the integration surface and the control(collocation)surface,resulting in a BIE with non-singular *** desingularization allows simpler and faster numerical evaluation of the boundary integrals,and consequently faster numerical *** this paper,derivations of different forms of DBIEs are given and the fundamental aspects and advantages of the DBIEs are reviewed and *** examples of applications of DBIEs in wave dynamics and body motion dynamics are given and the outlook of future development of the desingularized methods is discussed.

关键词： Desingularized boundary integral equations Potential flows Wave dynamics Wave-body interactions.

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用于微量精密切削的创新的电主轴系统

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现代制造 2008年第20期 38-40页

作者： Rudolf Walter j.rgen beck

在切削加工中,为适应不断增加的小型工件的精密加工要求,应提高铣床的精度并实现刀具的小型化。铣削电主轴在此加工中起到关键的作用。新一代的主轴对转速、精度和可靠性的要求明显提高。

关键词：电主轴系统精密切削创新切削加工加工要求小型工件小型化可靠性

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New insights for the catalytic oxidation of cyclohexane to K-A oil

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journal of Energy Chemistry 2022年第7期31卷 45-51,I0002页

作者： Alessandro Vomeri Marta Stucchi Alberto Villa Claudio Evangelisti rea beck Laura Prati Dipartimento di Chimica Universitàdegli Studi di MilanoVia Golgi 1920133MilanoItaly CNR-ICCOM-Istituto di Chimica dei Composti Organo Metallici Via G.Moruzzi 1I-56124 PisaItaly Centre for Energy Research Surface Chemistry and Catalysis DepartmentP.O.Box 49H-1525 BudapestHungary

Au-based catalysts have been reported to be active in the cyclohexane oxidation to K-A oil, but they showed some limitiations in terms of productivity, selectivity and required reaction conditions. The possibility to overcome some of these limits has been explored coupling Au with Cu, which can be suitable for undergoing the electron-switch in the initial step of the cyclohexane oxidation. Hence, a bimetallic 2 wt% Au Cu/Al_(2)O_(3) catalyst was tested in the oxidation of cyclohexane, working at mild conditions of 120 ℃ and 4 bar of O_(2). The combination of the catalyst with a very small amount of benzaldehyde used as cheaper and non-toxic radical initiator allowed to obtain a very high productivity of cyclohexanol and cyclohexanone(45 mmol*m L/mgmet*h) with a selectivity of 94%. Moreover, comparing the catalysed reaction with the non-catalysed one, the role of the catalyst has been disclosed.

关键词： K-A oil Cyclohexane oxidation Benzaldehyde Radical initiator Heterogeneous catalysis Radical mechanism AuCu bimetallic catalyst

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Conception of a new 4-quadrant hydrogen compressed air energy storage power plant with an integrated electrolyzer

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Energy Reviews 2024年第3期3卷 92-101页

作者： Hans-Peter beck Ann-Kathrin Klaas Christoph Klaas Research Center Energy Storage Technologies Clausthal University of TechnologyAm Stollen 19A38640GoslarGermany Institute of Electrical Power Engineering and Energy Systems Clausthal University of TechnologyLeibnizstraße 2838678Clausthal-ZellerfeldGermany

A hydrogen compressed air energy storage power plant with an integrated electrolyzer is ideal for large-scale,long-term energy storage because of the emission-free operation and the possibility to offer multiple ancillary services on the German energy *** paper defines analyzes such a storage concept and conducts an extensive comparison with four additional storage concepts based on various *** results show that the combination of storing compressed air and hydrogen offers a higher efficiency than storing only hydrogen and lower specific investment costs than storing only compressed *** result is confirmed with analysis of the optimal sizing of each power plant component for simultaneous participation on multiple energy markets with a linear optimization dispatch *** hydrogen compressed air energy storage(HCAES)power plant can utilize more revenue possibilities than a hydrogen energy storage because of the higher round-trip efficiency and the combination of the air compressor and the integrated electrolyzer during charging *** integration of the electrolyzer,however,offers a couple of challenges itself because of the highly flexible operation mode.A new concept for the controllable 24-pulse diode-thyristor rectifier of the electrolyzer is presented,that uses mostly common components while offering little to no grid harmonics and a long *** flexible integrated electrolyzer allows for the 4-quadrant operation of the storage power plant.

关键词： Long-term energy storage Hydrogen energy storage Compressed air energy storage Mixed-integer linear programming Electrolyzer 24-Pulse thyristor rectifier

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