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journal of Pharmaceutical Analysis 2024年第4期14卷 622-622页

作者： Bingjia Zhao Qian Zhang Yiqian He Weifang cao Wei Song Xiaochun Liang Department of Traditional Chinese Medicine Peking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijing100730China Institute of Basic Medical Sciences Chinese Academy of Medical SciencesBeijing100005China Medical Research Center Peking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijing100730China

Original statement in the caption of Fig.5:***(jMT)treatment restored the perturbed central carbohydrate metabolism in the circulation and sciatic nerve of diabetic peripheral neuropathy(DPN)*** line arrows indicate the direct metabolic reactions,and solid line arrows indicate the indirect reactions.*P<0.05 and**P<***:no significant ***:control;TCA:tricarboxylic acid cycle;ADP:adenosine diphosphate:ATP:adenosine triphosphate;GDP:guanosine diphosphate;GTP:guanosine triphosphate.

关键词： protective neuropathy metabolism

平震结合理念下的城市应急避难场所震后应急厕所设计研究

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防灾减灾工程学报 2024年第4期44卷 813-825页

作者：赵锋曹伊然代璐伍思莹西安建筑科技大学艺术学院陕西西安710055

探讨平震结合理念在城市应急避难场所中的运用方法,以解决震后缺乏正常运转厕所的问题并降低灾时专用应急厕所建造过程中的资源浪费,进一步讨论未来城市应急避难场所厕所的发展趋势,为研究者提供相关设计思路与发展动向。通过对震后城... 详细信息

探讨平震结合理念在城市应急避难场所中的运用方法,以解决震后缺乏正常运转厕所的问题并降低灾时专用应急厕所建造过程中的资源浪费,进一步讨论未来城市应急避难场所厕所的发展趋势,为研究者提供相关设计思路与发展动向。通过对震后城市应急避难场所人群流量、活动时长以及人群组成的详细分析,梳理受灾人群对应急厕所的需求。在此基础上,从应急厕所规划配置、内部空间、围护结构以及地下结构4个方面构建符合群众需求的应急厕所设计架构。在应急厕所设计中,引入平震结合的理念有助于降低建造震后应急厕所所需的耗材,同时满足不同使用人群的需求。这一理念为应急厕所设计提供了新的路径与理念,成为设计过程的重要依据,为今后应急避难场所及设施的建设与发展提供新思路。

关键词：平震结合应急避难场所及设施应急厕所设计方法

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金蝉花多糖改善矽肺小鼠肺纤维化的作用研究

中华劳动卫生职业病杂志 2024年第9期42卷 641-649页

作者：操磊王国亮陈蕾刘胜萍安徽医科大学合肥第三临床学院(合肥市第三人民医院)职业病科合肥安徽医科大学合肥第三临床学院(合肥市第三人民医院)放射科合肥安徽大学生命科学学院合肥

目的通过气管滴注二氧化硅(SiO2)颗粒构建小鼠矽肺模型, 探究金蝉花多糖(CCP)对矽肺小鼠肺纤维化的改善作用和机制。方法于2023年5月, 提取分离得到CCP, 采用高效液相色谱和傅里叶变换红外光谱分析其单糖组成和官能团构成。C57BL/6j小... 详细信息

目的通过气管滴注二氧化硅(SiO2)颗粒构建小鼠矽肺模型, 探究金蝉花多糖(CCP)对矽肺小鼠肺纤维化的改善作用和机制。方法于2023年5月, 提取分离得到CCP, 采用高效液相色谱和傅里叶变换红外光谱分析其单糖组成和官能团构成。C57BL/6j小鼠气管滴注50 μl 50 mg/ml的SiO2混悬液以制备矽肺小鼠模型, 然后将造模成功的小鼠随机分为模型组、CCP干预组[低剂量组(LCCP组)、中剂量组(MCCP组)和高剂量组(HCCP组)], 对照组滴注50 μl生理盐水, 每组8只。CCP干预组每天分别灌胃一次100、200和400 mg/kg的CCP溶液, 对照组和模型组灌胃生理盐水, 连续给药30 d。记录小鼠体重并计算肺系数, 采用HE和Masson染色检测小鼠肺组织的病理形态学变化;ELISA法测定肺组织中纤维化相关指标[羟脯胺酸(HYP)、结缔组织生长因子(CTGF)和基质金属蛋白酶-2(MMP-2)]、肺组织和肺泡灌洗液中促炎因子[肿瘤坏死因子α(TNF-α)、白细胞介素1β(IL-1β)和白细胞介素6(IL-6)]的含量;免疫组化法测定小鼠肺组织Ⅰ型胶原蛋白(CollagenⅠ)的表达;Western blot法检测肺组织中转化生长因子β1(TGF-β1)、P-Smad2、α-平滑肌肌动蛋白(α-SMA)、Toll样受体4(TLR4)、核因子κB p65亚基(NF-κBp65)和髓性分化原发应答基因88(MyD88)的相对表达量。结果 CCP总糖含量为86.78%, 由D-甘露糖、D-鼠李糖、D-葡萄糖和D-半乳糖组成, 其摩尔比为12.71∶1.53∶1.00∶12.64, 红外光谱表明具有多糖的特征基团。与对照组比较, 模型组小鼠体重降低, 肺系数升高, 肺组织中HYP、CTGF和MMP-2的含量升高, 肺组织和肺泡灌洗液中TNF-α、IL-1β和IL-6含量升高(P<0.05);肺组织显示大量炎症细胞浸润和胶原纤维沉积, 矽肺纤维化程度严重;肺组织CollagenⅠ表达上调, TGF-β1、P-Smad2/Smad2、α-SMA、TLR4、NF-κBp65和MyD88的相对蛋白表达水平升高(P<0.05)。与模型组比较, MCCP组和HCCP组小鼠体重升高, 肺系数降低, 肺组织中HYP、CTGF和MMP-2的含量降低, 肺组织和肺泡灌洗液中TNF-α、IL-1β和IL-6含量降低(P<0.05);肺部炎症细胞浸润减轻, 纤维化程度具有不同程度的改善;肺组织CollagenⅠ表达下调, TGF-β1、P-Smad2/Smad2、α-SMA、TLR4、NF-κBp65和MyD88的相对蛋白表达水平降低(P<0.05)。结论 CCP可通过抑制TGF-β1/Smad通路和TLR4/核因子κB(NF-κB)通路的激活, 降低肺组织中纤维化相关指标和促炎因子的水平, 改善SiO2颗粒导致的小鼠肺部炎症和矽肺纤维化。

关键词：矽肺肺纤维化金蝉花多糖炎症 TGF-β1/Smad通路 TLR4/NF-κB通路

Releasing the residual stress of C_(f)/SiC-GH3536 joint by designing an Ag-Cu-Ti+Sc_(2)(WO_(4))_(3) composite filler metal

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journal of Materials Science & Technology 2022年第13期108卷 102-109页

作者： P.Wang X.Liu H.Wang j.cao j.Qi j.Feng State Key Laboratory of Advanced Welding and joining Harbin Institute of TechnologyHarbin 150001China

Due to native character of thermal expansion coefficient(CTE)mismatch between C_(f)/SiC and GH3536,achieving high strength joint was a huge challenge for C_(f)/SiC-GH3536 ***,a composite filler metal of Ag-Cu-Ti+Sc_(2)(WO_(4))_(3) was developed to join C_(f)/SiC and *** work introduced Sc_(2)(WO_(4))_(3) to Ag-Cu-Ti system as a negative thermal expansion(NTE)reinforcing phase to release joint residual ***_(2)(WO_(4))_(3) was evenly distributed in the brazing seam and reacted with Ti to form Ti_(3)O_(5) reaction *** results of finite element analysis showed that the residual stress of the joints was effectively released by introducing Sc_(2)(WO_(4))_(3) reinforcing phase,and the mises stress was decreased from447 to 401 *** maximum shear strength of the C_(f)/SiC-GH3536 joint brazed with Ag-Cu-Ti+6 vol%Sc_(2)(WO_(4))_(3) filler alloys was 64 MPa,which was about 2.6 times higher than that of Ag-Cu-Ti *** results of this study provide a promising strategy for the introduction of new Sc_(2)(WO_(4))_(3) reinforcing phase in Ag-Cu-Ti system,and improve the reliability and feasibility of composite brazing alloy in brazing filed.

关键词： Negative thermal expansion Brazing Residual stress Composite brazing alloy CTE

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船舶对明渠水流运动的影响模型试验研究

长江科学院院报 2024年第5期41卷 87-94页

作者：曹向楠姚仕明丁兵范达福长江科学院河流研究所武汉430010

为了探求船舶对于明渠水流运动的影响,利用水位测针和粒子图像测速(Particle Image Velocimetry,PIV)系统分别测量了明渠水流中不同吃水工况下船舶前、后的沿程水深及流场,分析了位于船舶中间纵剖面上的流速分布特征。结果表明:①相较... 详细信息

为了探求船舶对于明渠水流运动的影响,利用水位测针和粒子图像测速(Particle Image Velocimetry,PIV)系统分别测量了明渠水流中不同吃水工况下船舶前、后的沿程水深及流场,分析了位于船舶中间纵剖面上的流速分布特征。结果表明:①相较于无船工况,船前水深略有增加,船后水深略有减少;且船舶对水深的影响程度随着吃水深度的增加而增加,有船与无船水深的比值最大为1.071,最小为0.951;②船舶中间纵剖面上纵向垂线流速分布从船头前“j”型向船舶底部的“■”型转变,流经船尾后逐渐恢复为“j”型,且在船头附近形成下潜水流、船尾附近形成上升水流;③在船舶吃水深度为0.6 h时,纵向(沿水流方向)与垂向(沿水深方向)上都出现各个工况下的最大流速,纵向流速最大值达到无船时平均纵向流速的2.11倍,位于船头附近(x/l=-2/5);下潜水流流速最大值达到无船时平均纵向流速的71%,位于船头附近(x/l=-0.5);上升水流流速最大值达到无船时平均纵向流速的29%,位于船尾附近(x/l=2/3)。

关键词：船舶粒子图像测速(PIV) 水深流速分布明渠水流

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STUDY OF THE X70 PIPELINE STEEL CORRODIng IN 3.0wt% NaCl SOLUTION USIng ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY TECHNIQUE

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Acta Metallurgica Sinica(English Letters) 2004年第6期17卷 907-911页

作者： L.j.Zhang Z.Zhang F.H.cao j.Q.Zhang j.M.Wang C.N.cao DepartmentofChemistry ZhejiangUniversityHangzhou310027China DepartmentofChemistry ZhejiangUniversityHangzhou310027China／／ StateKeyLaboratoryforCorrosionandProtectionofMetalsInstituteofMetalResearchTheChineseAcademyofSciencesSlaenyang110016China

The corrosion process of the X70 pipeline steel in 3.0wt% NaCl solution were studied using polarization method, and the chronological characteristics during the entire polarization plot were investigated in detail using EIS technique. In the active region of X70 steel, such as 20mV potential bias applied on open circuit potential (OCP), the impedance spectra was comprised of three parts: a high-frequency capacitive loop, a middle-frequency capacitive loop and a low-frequency inductive component. When positive polarization potential increased, the capacitive loops at high and middle frequency range merged, and the inductive component at low frequency shrunk. At high positive polarization potential bias (500-800mV vs. OCP), the high-frequency capacitive loop and the low-frequency inductive loop exhibited as disheveled points due to the synergism of the inhomogeneity of the corroding material and the localized corrosion. The results were fitted utilizing the equivalent circuits to simulate the impedance spectra and to interpret the electrochemical features shown during the experiments.

关键词： X70 pipeline steel corrosion polarization EIS

Propagation of surfactant and polymer flow in natural carbonate cores

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Petroleum 2022年第3期8卷 414-423页

作者： Dongqing cao jinxun Wang Ming Han Amar j.Alshehri Beij.ng Research Center Aramco AsiaBeijing100102PR China EXPEC Advanced Research Center Saudi AramcoDhahran31311Saudi Arabia

This paper presents an experimental and analytical study of comprehensive effects of surfactant and polymer in aqueous solutions on the propagation in ***-phase flow tests of surfactant,polymer and surfactant-polymer mixture were respectively conducted on natural carbonate core plugs at high temperature and high salinity reservoir *** effect of different factors on chemical propagation was taken into account by use of a convection-dispersion *** dynamic adsorptions of two amphoteric surfactants at 2000 mg/L concentration onto the carbonate rocks were 0.21 and 0.17 mg/g-rock,*** dynamic adsorptions of a sulfonated polymer at 2000 and 5000 mg/L were 0.11 and 0.17 mg/g-rock,***-polymer mixtures in aqueous solutions were coinjected to evaluate their competitive adsorption,showing the surfactant adsorption was reduced by approximately 50%.The dispersion coefficient of the chemicals in the carbonate cores was in the magnitude of 10^(-3) cm^(2)/*** by dispersion and adsorption,chemical concentration reduction occurred obviously during the propagation in carbonate porous *** separation took place in the surfactant-polymer co-injection scheme,which was estimated by modeling as well.

关键词： Natural carbonate core Chemical propagation Polymer Surfactant Competitive adsorption Convention-dispersion model

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英语原著阅读对大学生语感提升的研究与实践

黑河学院学报 2024年第8期15卷 99-102页

作者：韩敏曹红山西医科大学汾阳学院山西吕梁032200

英语作为一门世界语言,在我国的地位日益显著。大学生作为国家未来的发展中坚力量,英语能力的提高尤为重要。语感是英语能力的重要组成部分,包括对语言的感知、理解、表达和应用能力。近年来,许多研究表明,阅读英语原著对于提高大学生... 详细信息

英语作为一门世界语言,在我国的地位日益显著。大学生作为国家未来的发展中坚力量,英语能力的提高尤为重要。语感是英语能力的重要组成部分,包括对语言的感知、理解、表达和应用能力。近年来,许多研究表明,阅读英语原著对于提高大学生的语感具有积极的意义。大学生阅读英语原著时,涉及词汇量、语法、语义联系、文化范围及思维转变等多方面内容,对其语感提升是综合性的,通过多种方式加强、深化原著阅读,对提高教学效果会产生重要作用。

关键词：英语原著阅读语感提升大学生阅读策略

One-pot In-situ Synthesis of Sn/Carbon-fibers Nanocomposite by Chemical Vapor Deposition and Its Li-storage Properties

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journal of Materials Science & Technology 2012年第3期28卷 275-279页

作者： j.Xie Yunxiao Zheng Shuangyu Liu Gaoshao cao Xinbing Zhao Department of Materials Science and Engineering Zhejiang UniversityHangzhou 310027China

Sn/carbon-fibers（CFs） nanocomposite has been prepared by chemical vapor deposition with in-situ catalytic growth of *** nanocomposite has been characterized by X-ray diffraction（XRD）,field emission scanning electron microscopy（FE-SEM）,transmission electron microscopy（TEM） and Raman *** electrochemical performance of the nanocomposite has been investigated by galvanostatic cycling and cyclic voltammetry（CV）.It has been found that a three-dimensional conductive network forms by the interconnected CFs,which offers conductive channels for the Sn *** nanocomposite gives a first charge capacity of 385 mAh.g-1 and exhibits an improved cycling stability than bare Sn.

关键词： Sn/carbon-fibers In-situ catalytic growth Three-dimensional conductive network Li-storage properties

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配筋UHPC预制管混凝土组合柱轴压试验

兰州大学学报（自然科学版） 2024年第2期60卷 253-261页

作者：欧智菁陈玮悦颜建煌曹磊福建理工大学建省土木工程新技术与信息化重点实验室福州350118

为研究超高性能混凝土(UHPC)相对于钢筋混凝土(RC)柱的基本受力性能,以UHPC预制管配箍率和长/细比为试验参数,对6根配筋UHPC预制管混凝土组合柱进行轴压试验.结果表明,与RC柱和UHPC预制空心柱相比,配筋UHPC预制管混凝土组合柱能明显改... 详细信息

为研究超高性能混凝土(UHPC)相对于钢筋混凝土(RC)柱的基本受力性能,以UHPC预制管配箍率和长/细比为试验参数,对6根配筋UHPC预制管混凝土组合柱进行轴压试验.结果表明,与RC柱和UHPC预制空心柱相比,配筋UHPC预制管混凝土组合柱能明显改善RC柱的压溃现象和UHPC的脆性特征.为更好地发挥共同受力作用,应让紧箍效应提早出现.采用ABAQUS软件建立组合柱的有限元计算模型,分析表明UHPC强度、径/厚比、 UHPC配箍率、长/细比是影响配筋UHPC预制管混凝土组合柱轴压试验结果的重要参数.

关键词：超高性能混凝土预制管组合柱静力试验有限元