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National Science r.view 2024年第1期11卷 8-10页

作者： David j.Bottjer Depar.ment of Ear.h Sciences University of Southern California

The defining featur. of a mass extinction and its associated r.cover. is the global amount of extinction that occur.ed[1]. However. ther. is finer.scale detail to the stor., as seen in the ongoing moder. mass extinction(the sixth mass extinction), which exhibits var.able effects among mar.ne ecosystems and envir.nments, and hence geogr.phic ar.as [1].

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Global weir.ing at mass extinction hor.zons

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National Science r.view 2024年第1期11卷 10-12页

作者： Gr.gor. j.r.tallack Depar.ment of Ear.h Sciences University of Oregon

A str.ng motivation for.studying mass extinctions is under.tanding how cur.ent climatic and biodiver.ity cr.ses will affect cr.atur.s living on land such as our.elves. Per.aps the question is: how bad can it get? In that case, ter.estr.al Per.ian-Tr.assic mass extinctions ar. an ir.esistible wor.t-case scenar.o [1].

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Solid-liquid extr.ction for.yttr.um r.cover. using por.us polymer.c r.sin(XAD-7) functionalized with D_(2)EHPA

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jour.al of r.r. Ear.hs 2024年第9期42卷 1764-1773,I0005页

作者： P.A.Mar.ínez-Montoya r.G.Sanchez-Alvar.do D.Y.Medina-Velazquez M.L.Car.er.-jota P.Gar.ica-Chávez A.de j.Mor.les-r.mir.z Higher.School of Chemical Engineer.ng and Extr.ctive Industr.es ESIQIEIPNDepartment of Metallurgical EngineeringUPALM S/NCol.LindavistaGustavo A.Madero Cd.de MéxicoC.P07738Mexico Metr.politan Autonomous Univer.ity Department of MaterialsBasic Sciences and EngineeringAv.San Pablo No.180Col.Reynosa TamaulipasCd.de MéxicoC.P02200Mexico Center.for.r.sear.h and Technological Innovation CIITECIPNCda.de CECATIs/nSanta CatarinaAzcapotzalcoC.P02250CDMXMexico

The r.cover. of yttr.um is pr.posed by applying a solid-liquid extr.ction pr.cess using di-2-ethyl hexylphosphor.c acid(D2EHPA) as extr.cting *** extr.cting agents wer. suppor.ed on a macr. por.us polymer.c r.sin XAD-7(solid phase).Yttr.um ions extr.ction and dischar.e tests wer. per.or.ed,fir.tly fr.m a synthetic aqueous solution of 100 mg/L Y(liquid phase) at 25℃ with *** effects of pH of aqueous solutions bear.ng yttr.um,volume fr.ction of extr.cting agents and the solid/liquid(S/L)r.tio on the yttr.um r.cover. wer. *** most favor.ble conditions for.yttr.um ions extr.ction ar.;20 vol% D_(2)EHPA functionalized r.sin,pH=1.5 and an S/L r.tio of 10 mg/mL The dischar.e of yttr.um ions was done under.the same conditions of extr.ction stage,using a 2 mol/L [H_(2)SO_(4)] as str.pping *** to 80% yttr.um is extr.cted,while 75% yttr.um is r.cover.d in the str.ping *** all exper.ments,the r.action equilibr.um is r.ached after.20 min,and the kinetics for.the extr.ction stage was deter.ined as a second-or.er.***,exper.ments wer. car.ied out to dischar.e the yttr.umloaded r.sins,and it has been deter.ined that the best pH value to str.p the Y ions is *** tests of extr.ction and dischar.e for.yttr.um ions show that the functionalized r.sin can wor. at least five cycles without decr.asing its ***,the pr.posed pr.cess was tested in a r.al solution with Y ions fr. m a waste fluor.scent la mp powder.leached in H_(2)SO_(4),demonstr.ting the ability to effectively r.cover.yttr.um,separ.ting it fr.m var.ous metals fr.m the studied r.sidue.

关键词： Yttr.um r.cover. r.r. ear.h solid-liquid extr.ction XAD-7 r.sin Fluor.scent lamps r.cycling Solid-liquid kinetics extr.ction

Changes in snow cover.extent in the Centr.l Taur.s Mountains fr.m 1981 to 2021 in r.lation to temper.tur., pr.cipitation, and atmospher.c teleconnections

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jour.al of Mountain Science 2024年第1期21卷 49-67页

作者： Ecmel Er.AT Fulya AYDIN-KANDEMİr Depar.ment of Geogr.phy Ege UniversityIzmir 35100Türkiye Climate Change and Zer. Waste Depar.ment Antalya Metropolitan MunicipalityAntalya 07310Türkiye Hydr.politics Association Ankara 06680Türkiye

The snow cover.over.the Taur.s Mountains affects water.supply, agr.cultur., and hydr.power.gener.tion in the r.gion. In this study, we analyzed the monthly Snow Cover.Extent(SCE) fr.m November.to Apr.l in the Centr.l Taur.s Mountains(Bolkar. Aladaglar. Tahtali and Binboga Mountains) fr.m 1981 to 2021. Linear.tr.nds of snow cover.season(November.to Apr.l) over.the last 41 year. showed decr.ases in SCE pr.mar.ly at lower.elevations. The downwar. tr.nd in SCE was found to be mor. pr.nounced and statistically significant for.only November.and Mar.h. SCE in the Centr.l Taur.s Mountains has declined about-6.3% per.decade for.2500-3000 m in November.and about-6.0% per.decade for.1000-1500 m and 3000+ m in Mar.h over.the last 41 year.. The loss of SCE has become evident since the 2000s, and the lowest negative anomalies in SCE have been obser.ed in 2014, 2001, and 2007 in the last 41 year., which ar. consistent with an incr.ase in air.temper.tur. and decr.ased pr.cipitation. SCE was cor.elated with both mean temper.tur. and pr.cipitation, with temper.tur. having a gr.ater.r.lative impor.ance at all elevated gr.dients. r.sults showed that ther. is a str.ng linear.r.lationship between SCE and the mean air.temper.tur.(r.=-0.80) and pr.cipitation(r.= 0.44) for.all elevated gr.dients dur.ng the snow season. The Ar.tic Oscillation(AO), the Nor.h Atlantic Oscillation(NAO), and the Mediter.anean Oscillation(MO) winter.indices wer. used to explain the year.to-year.var.ability in SCE over.the Centr.l Taur.s Mountains. The r.sults showed that the inter.annual var.ability obser.ed in the winter.SCE on the Centr.l Taur.s Mountains was positively cor.elated with the phases of the winter.AO, NAO and MO, especially below 2000 m elevation.

关键词： Snow cover.extent Atmospher.c teleconnection Centr.l Taur.s Mountains Air.temper.tur. and pr.cipitation Geogr.phic Infor.ation Systems Tür.iye

Neur.genic potential of NG2 in neur.tr.uma:a systematic r.view

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Neur.l r.gener.tion r.sear.h 2024年第12期19卷 2673-2683页

作者： Yur. r.r.go r.dhar.ni Benvenutti Luis V.Por.ela Nathan r.Str.gulski Depar.amento de Bioquímica Instituto de Ciências Básicas da SaúdeUniversidade Federal do Rio Grande do Sul(UFRGS)Porto AlegreBrazil School of Phar.acy and Biomolecular.Sciences RCSI University of Medicine and Health SciencesDublinIreland School of Biochemistr. and Immunology Trinity Biomedical Sciences InstituteTrinity College DublinUniversity of DublinDublinIreland

r.gener.tive appr.aches towar.s neur.nal loss following tr.umatic br.in or.spinal cor. injur. have long been consider.d a dogma in neur.science and r.main a cutting-edge ar.a of *** is r.flected in a lar.e dispar.ty between the number.of studies investigating pr.mar. and secondar. injur. as ther.peutic to r.ets in spinal co r. and tr.umatic br.in *** advances in biotechnology may have the potential to r.shape the cur.ent state-of-the-ar. and br.ng focus to pr.mar. injur. neur.tr.uma *** studies using neur.l-glial factor.antigen 2(NG2)cells indicate that they may differ.ntiate into neur.ns even in the developed *** these cells show gr.at potential to play a r.gener.tive r.le,studies have been conducted to test var.ous manipulations in neur.tr.uma models aimed at eliciting a neur.genic r.sponse fr.m *** the pr.sent study,we systematically r.viewed the exper.mental pr.tocols and findings descr.bed in the scientific liter.tur.,which wer. peer.r.viewed or.ginal r.sear.h ar.icles(1)descr.bing pr.clinical exper.mental studies,(2)investigating NG2 cells,(3)associated with neur.genesis and neur.tr.uma,and(4)in vitr. and/or.in vivo,available in PubMed/MEDLINE,Web of Science or.SCOPUS,fr.m 1998 to ***,we have r.viewed a total of 1504 paper.,and summar.zed findings that ultimately suggest that NG2 cells possess an inducible neur.genic potential in animal models and in *** also discr.minate findings of NG2 neur.genesis pr.moted by differ.nt phar.acological and genetic appr.aches over.functional and biochemical outcomes of tr.umatic br.in injur. and spinal co r. injur. models,and pr.vide mounting evidence for.the potential benefits of manipulated NG2 cell ex vivo tr.nsplantation in pr.mar. injur. *** findings indicate the feasibility of NG2 cell neur.genesis str.tegies and add new player. in the development of ther.peutic alter.atives for.neur.tr.uma.

关键词： neur.l-glial antigen 2 neur.l-glial factor.2 neur.n differ.ntiation NG2 cell r.gener.tion spinal cor. injur.(SCI) tr.umatic br.in injur.(TBI)

Par.metr.c investigation on the novel and cost-effective nano fly ash impr.gnated geopolymer.system for.sustainable constr.ction

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Fr.ntier. of Str.ctur.l and Civil Engineer.ng 2024年第2期18卷 170-183页

作者： r.MOHANA S.M.Leela BHAr.THI Depar.ment of Civil Engineer.ng Mepco Schlenk Engineering CollegeSivakasi 626123India

The hazar.ous envir.nmental effects of gr.enhouse gas emissions and climate change demand alter.ative sour.es for.cementitious mater.als in the constr.ction *** development of geopolymer.str.ctur.s pr.vides a way of pr.ducing 100%cement-fr.e *** this r.sear.h wor.,a novel and simple way of der.ving nano par.icles fr.m waste fly ash par.icles is *** effect of adding the synthesized nano fly ash par.icles as a filler.medium in geopolymer.mor.ar. was investigated by consider.ng str.ngth and dur.bility *** optimization was done by using r.gr.ssion analysis on the geopolymer.mor.ar.and the impact of adding nano fly ash par.icles was studied by var.ing differ.nt per.entages of addition r.nging fr.m 0 to 7.5%by weight of binder.*** the r.sults,it was obser.ed that 1%nano fly ash acted not only as a filler.but also as nano-sized pr.cur.or. of the polymer.zation pr.cess,r.sulting in denser.geopolymer.*** can explain the extr.or.inar. gain in str.ngth of 72.11 MPa as well as the denser.cor. with negligible level of chlor.de ion penetr.tion,making the mater.al suitable for.the development of str.ctur.s susceptible to mar.ne envir.nment.

关键词： geopolymer nano fly ash chlor.de ion penetr.tion dur.bility polymer.zation filler.

Metabolic r.pr.gr.mming by Syntenin-1 dir.cts r. FLS and endothelial cell-mediated inflammation and angiogenesis

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Cellular.& Molecular.Immunology 2024年第1期21卷 33-46页

作者： Anja Meyer.Stephanie r.Zack Wes Nijim Adel Bur.os Vishwa Patel Br.an Zanotti Michael V.Volin M.Asif Amin Myles j.Lewis Costantino Pitzalis Shiva Ar.mi joseph A.Kar.m Nader. j.Sweiss Shiva Shahr.r. jesse Br.wn VA Medical Center ChicagoILUSA Depar.ment of Medicine Division of RheumatologyThe University of Illinois at ChicagoChicagoILUSA Depar.ment of Micr.biology and Immunology Midwestern UniversityDowners GroveILUSA Division of r.eumatology and Clinical Autoimmunity Center.of Excellence University of MichiganAnn ArborMIUSA Centr. for.Exper.mental Medicine and r.eumatology William Harvey Research InstituteBarts and The London School of Medicine and DentistryQueen Mary University of LondonLondonUnited Kingdom Centr. for.Exper.mental Medicine&r.eumatology William Harvey Research InstituteQueen Mary University of London and Barts NIHR BRC&NHS TrustLondonUK Depar.ment of Biomedical Sciences Humanitas Universityand Humanitas Research HospitalMilanItaly Depar.ment of Or.hopedic Sur.er. the University of Illinois at ChicagoChicagoILUSA

A novel r.eumatoid ar.hr.tis(r.)synovial fluid pr.tein,Syntenin-1,and its r.ceptor.Syndecan-1(SDC-1),ar. colocalized on r. synovial tissue endothelial cells and fibr.blast-like synoviocytes(FLS).Syntenin-1 exacer.ates the inflammator. landscape of endothelial cells and r. FLS by upr.gulating tr.nscr.ption of Ir.1/5/7/9,IL-1β,IL-6,and CCL2 thr.ugh SDC-1 ligation and HIF1α,or.mTOr.***,Syntenin-1 or.hestr.tes r. FLS and endothelial cell invasion via SDC-1 and/or.mTOr.*** Syntenin-1 r.pr.gr.mmed endothelial cells,the dynamic expr.ssion of metabolic inter.ediates coincides with escalated glycolysis along with unchanged oxidative factor.,AMPK,PGC-1α,citr.te,and inactive oxidative ***,r. FLS r.wir.d by Syntenin-1 displayed a modest glycolytic-ATP accompanied by a r.bust mitochondr.al-ATP *** enr.ched mitochondr.al-ATP detected in Syntenin-1 r.pr.gr.mmed r. FLS was coupled with mitochondr.al fusion and fission r.capitulated by escalated Mitofusin-2 and Dr.1 *** found that VEGFr./2 and Notch1 networ.s ar. r.sponsible for.the cr.sstalk between Syntenin-1 r.wir.d endothelial cells and r. FLS,which ar. also r.pr.sented in r. *** to r. explants,mor.hological and tr.nscr.ptome studies authenticated the impor.ance of VEGFr./2,Notch1,r.PTOr.and HIF1αpathways in Syntenin-1 ar.hr.tic mice and their.obstr.ction in SDC-1 deficient ***,dysr.gulation of SDC-1,mTOr.and HIF1αnegated Syntenin-1 inflammator. phenotype in r. explants,while inhibition of HIF1αimpair.d synovial angiogenic impr.nt amplified by *** conclusion,since the cur.ent ther.pies ar. ineffective on Syntenin-1 and SDC-1 expr.ssion in r. synovial tissue and blood,tar.eting this pathway and its inter.onnected metabolic inter.ediates may pr.vide a novel ther.peutic str.tegy.

关键词： Syntenin-1 Syndecan-1 r. FLS r. explants immunometabolism

BaTiO3 solid solutions co-doped with Gd3+ and Eu3+:Synthesis,str.ctur.l evolution and dielectr.c pr.per.ies

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jour.al of r.r. Ear.hs 2024年第10期42卷 1920-1926页

作者： r.Mar.ínez-López M.Pér.z-Labr. j.A.r.mer.-Ser.ano F.r.Bar.ientos-Her.ández M.r.yes-Pér.z M.I.Valenzuela-Car.illo G.Ur.ano-r.yes V.E.r.yes-Cr.z G.I.Dávila-Pulido Academic Ar.a of Ear.h Sciences and Mater.als Autonomous University of Hidalgo State Metallur.y and Mater.als Depar.ment ESIQIE-IPNUPALM Autonomous Univer.ity of Coahuila Boulevard Adolfo López Mateos S/n

In this paper.the synthesis,str.ctur.l evolution,and dielectr.c pr.per.ies of BaTiO3solid solutions codoped with r.r. ear.h elements(Gd3+and Eu3+) pr.par.d using the solid-state r.action method ar. *** pur. pr.cur.or.powder. of BaCl3,TiO2,Gd2O3,and Eu2O3wer. mixed in stoichiometr.c pr.por.ions,gr.und in an agate mor.ar.befor. being uniaxially pr.ssed at 250 MPa and sinter.d at 1300℃ in air.atmospher. for.6 h to obtain Ba1-3xGd2xTi1-3xEu4xO3（x=0,0.0015,0.01 and0.1）.X-r.y diffr.ction（Xr.） and r.etveld's r.finement r.sults r.veal the cr.stal phase fer.oelectr.c tetr.gonal BaTiO3for.the samples with x=0,0.0015 and 0.01, as well as a consistent incr.ment in the lattice par.meter. caused by the *** solubility limit of Gd3+and Eu3+in the BaTiO3str.ctur. is r.ached for.the sample with x>0.01,and the or.hor.ombic Eu2TiO5and monoclinic BaTi2O5secondar. phases wer. *** r.man r.sults show the char.cter.stic peaks of fer.oelectr.c tetr.gonal BaTiO3ar.und 716 cm-1（LO of A1 symmetr.）,515 cm-1（TO of A1 symmetr.）,and 305 cm-1（B1）.The maximum r.lative per.ittivity measur.d at 1 kHz was r.cor.ed to be 6151.8 for.the sample with x=0.0015,and a decr.ase in the Cur.e temper.tur. to 105℃ with r.spect to the undoped sample was *** punctual micr.analysis for.the samples with x=0.0015,0.01,and 0.1 r.veals gr.ins composed of Ba,Ti,O,Gd,and Eu homogeneously distr.buted in the *** Ba/Ti r.tios for.samples with x=0.0015,0.01 and 0.1 ar. 2.86,2.91,and 0.68,r.spectively,indicating substitution at the Ti site for.samples with x=0.0015 and 0.01 and a substitution at the Ba site for.the sample with x=0.1.

关键词： BaTiO3 Doping Eur.pium Gadolinium r.r. ear.hs Synthesis

Nonlinear.dynamic modeling of planar.moving Timoshenko beam consider.ng non-r.gid non-elastic axial effects

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Applied Mathematics and Mechanics(English Edition) 2024年第3期45卷 479-496页

作者： M.ABBASI GAVAr. M.r.HOMAEINEZHAD Faculty of Mechanical Engineer.ng K.N.Toosi University of TechnologyTehran 19991-43344Iran

Due to the impor.ance of vibr.tion effects on the functional accur.cy of mechanical systems,this r.sear.h aims to develop a pr.cise model of a nonlinear.y vibr.ting single-link mobile flexible *** manipulator.consists of an elastic ar.,a r.tar. motor.and a r.gid car.ier.and under.oes gener.l in-plane r.gid body motion along with elastic tr.nsver.e *** accur.tely model the elastic behavior.Timoshenko’s beam theor. is used to descr.be the flexible ar.,which accounts for.r.tar. iner.ia and shear.defor.ation *** applying Newton’s second law,the nonlinear.gover.ing equations of motion for.the manipulator.ar. der.ved as a coupled system of or.inar. differ.ntial equations(ODEs)and par.ial differ.ntial equations(PDEs).Then,the assumed mode method(AMM)is used to solve this nonlinear.system of gover.ing equations with appr.pr.ate shape *** assumed modes can be obtained after.solving the char.cter.stic equation of a Timoshenko beam with clamped boundar. conditions at one end and an attached mass/iner.ia at the *** addition,the effect of the tr.nsver.e vibr.tion of the inextensible ar. on its axial behavior.is *** the axial r.gidity,the effect makes the r.gid body dynamics invalid for.the axial behavior.of the ***,numer.cal simulations ar. conducted to evaluate the per.or.ance of the developed model,and the r.sults ar. compar.d with those obtained by the finite element *** compar.son confir.s the validity of the pr.posed dynamic model for.the *** to the mentioned featur.s,this model can be r.liable for.investigating the system’s vibr.tional behavior.and implementing vibr.tion contr.l algor.thms.

关键词： planar.moving Timoshenko beam non-r.gid non-elastic axial effect as-sumed mode method(AMM) nonlinear.motion analysis

Decoding the genetic pr.gr.m of micr.nucleus for.ation: linking chr.mosomal instability to human disease

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Signal Tr.nsduction and Tar.eted Ther.py 2024年第7期9卷 2840-2842页

作者： jör. Fahr.r Division of Food Chemistr. and Toxicology Department of ChemistryRPTU Kaiserslautern-Landau67663 KaiserslauternGermany

A r.cent study by Adams and colleagues published in Natur. unveiled mor. than one hundr.d genes that ar. involved in micr.nucleus for.ation,1 which is a biomar.er.for.genomic instability and associated with aging,cancer.and other.disor.er..2 As an outstanding achievement,the author. identified DSCC1(DNA r.plication And Sister.Chr.matid Cohesion 1)as a cr.tical gene pr.tecting against ear.y developmental defects,genomic instability,r.duced pr.lifer.tive capacity,cohesinopathy-r.lated phenotypes,and tumor.development in vivo.

关键词： chr.mosomal linking r.plication