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Applied Mathematics and Mechanics(English Edition) 2024年第3期45卷 563-580页

作者： n.HUMnEKAR d.SRInIVASACHARYA department of Mathematics National Institute of TechnologyWarangal 506004TelanganaIndia

The influence of variable viscosity and double diffusion on the convective stability of a nanofluid flow in an inclined porous channel is *** darcyBrinkman model is used to characterize the fluid flow dynamics in porous *** analytical solutions are obtained for the unidirectional and completely developed *** on a normal mode analysis,the generalized eigenvalue problem under a perturbed state is *** eigenvalue problem is then solved by the spectral ***,the critical Rayleigh number with the corresponding wavenumber is evaluated at the assigned values of the other flow-governing *** results show that increasing the darcy number,the Lewis number,the dufour parameter,or the Soret parameter increases the stability of the system,whereas increasing the inclination angle of the channel destabilizes the ***,the flow is the most unstable when the channel is vertically oriented.

关键词： nanofluid inclined channel variable viscosity linear stability double dif-fusion porous medium

Recombinase Polymerase Amplification Based Rapid detection of Aroma Gene in Rice

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Rice science 2023年第2期30卷 96-99,I0010-I0013页

作者： Amrita BAnERjEE S.BHARTI j.KUMAR P.SAR PRIYAMEdHA n.P.MAndAL S.SARKAR Somnath roy Central Rainfed Upland Rice Research Station Indian Council of Agricultural Research(ICAR)-National Rice Research InstituteHazaribagJharkhand 825301India department of Biotechnology Vinoba Bhave UniversityHazaribagJharkhand 825301India Crop Improvement division ICAR-National Rice Research InstituteCuttackOdisha 753006India

Recombinase polymerase amplification(RPA) has been emerged as an alternative to PCR due to its high specificity and sensitivity in diagnostics of animal and plant pathogens. In this study, an RPA protocol was develope... 详细信息

关键词： specificity Rec emerged

nUMERICAL AnALYSIS OF HEAT TRAnSFER dURInG LASER CLAddInG TO SYnTHESIZE TiCp/Al COMPOSITE

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Acta Metallurgica Sinica(English Letters) 2004年第1期17卷 1-6页

作者： d.n.Zou j.Yang Y.L.Huang j.Y.Su School of Metallurgical Engineering Xi'an University of Architecture and Technology Xi'an 710055ChinaSchool of Metallurgical EngineeringXi'an University of Architecture and Technology Xi'an 710055ChinaSchool of Materials Science and Engineering Xi'an Jiaotong University Xi'an 710049 ChinaSchool of Materials Science and Engineering Xi'an Jiaotong University Xi'an 710049 China

Based on the continuum model for binary solid-liquid phase change system, the math-ematic model to simulate the process of laser cladding in situ synthesis TiCp/Al composite on the surface of aluminum alloy was formulated. The additive source method was employed to treat with the heat release of synthetic reaction in powder mixture at certain temperatures, and also to solve the momentum and heat transfer caused by the relative movement between laser beam and the specimen. Two different types of driving forces for flow were considered in the model, i.e., the buoyancy force and the surface tension gradient at the laser pool surface. The three-dimensional transient temperature field simulation program was developed being based upon the commercial software PHOEnICS. The calculated and observed fusion boundaries were compared and very good agreement was obtained.

关键词： numerical simulation heat transfer laser cladding in situ synthesis composite

Real-time four-dimensional scanning transmission electron microscopy through sparse sampling

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Chinese Physics B 2024年第11期33卷 34-38页

作者： A W Robinson j Wells A Moshtaghpour d nicholls C Huang A Velazco-Torrej.n G nicotra A I Kirkland n d Browning 无 SenseAI Innovations Ltd. LiverpoolUK Centre for doctoral Training University of LiverpoolLiverpoolUK Correlative Imaging Group Rosalind Franklin InstituteOxfordUK CnR-IMM Z.I.VIII Strada 5Catania95121Italy department of Mechanical Materialsand Aerospace EngineeringUniversity of LiverpoolLiverpoolUK

Four-dimensional scanning transmission electron microscopy(4-d STEM)is a state-of-the-art image acquisition mode used to reveal high and low mass elements at atomic *** acquisition of the electron momenta at each real space probe location allows for various analyses to be performed from a single dataset,including virtual imaging,electric field analysis,as well as analytical or iterative extraction of the object induced phase ***,the limiting factor in 4-d STEM is the speed of acquisition which is bottlenecked by the read-out speed of the camera,which must capture a convergent beam electron diffraction(CBEd)pattern at each probe position in the *** developments in sparse sampling and image inpainting(a branch of compressive sensing)for STEM have allowed for real-time recovery of sparsely acquired data from fixed monolithic detectors,Further developments in compressive sensing for 4-d STEM have also demonstrated that acquisition speeds can be increased,i.e.,live video rate 4-d imaging is now *** this work,we demonstrate the first practical implementations of compressive 4-d STEM for real-time inference on two different scanning transmission electron microscopes.

关键词： compressive sensing 4-d STEM inpainting

Structural and mass transport properties of liquid ytterbium in the temperature range 1123 K–1473 K

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Chinese Physics B 2023年第6期32卷 481-488页

作者： d d Satikunvar n K Bhatt B Y Thakore department of Physics Sardar Patel UniversityVallabh VidyanagarGujarat 388120India department of Physics Maharaja Krishnakumarsinhji Bhavnagar UniversityBhavnagarGujarat 364001India

We have studied the structural and atomic transport properties of liquid f-shell Yb in the temperature range 1123 K–1473 K. Pair interactions between atoms are derived using a local pseudopotential. The potential parameters are fitted to the phonon dispersion curve at room temperature. The local pseudopotential used in the present study is computationally more efficient with only three parameters, and it is found to be transferable to the liquid phase without changing the *** the various computed properties agree with reported theoretical and experimental findings, the adopted fitting scheme is justified. As a significant outcome of the study, we find that(i) the melting in Yb is governed by the Lindemann's law,(ii)the mass transport mechanism obeys the Arrhenius law,(iii) the role of the three-particle correlation function in deriving the velocity autocorrelation function is small,(iv) the mean-square atomic displacement is more sensitive to the choice of interaction potential than the other bulk properties, and(v) liquid Yb does not show liquid–liquid phase transition within the studied temperature range. Further, due to the good description of the structural and mass transport properties, we propose that Yb remains divalent at reduced density.

关键词： transport properties pseudopotential single-particle dynamics ytterbium

Mucopolysaccharidosis typeⅢB:a current review and exploration of the AAV therapy landscape

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neural Regeneration Research 2024年第2期19卷 355-359页

作者： Courtney j.Rouse Victoria n.j.nsen Coy d.Heldermon Lacerta Therapeutics AlachuaFLUSA University of Florida College of Medicine GainesvilleFLUSA

Mucopolysaccharidoses typeⅢB is a rare genetic disorder caused by mutations in the gene that encodes for *** results in the aggregation of heparan sulfate polysaccharides within cell lysosomes that leads to progressive and severe debilitating neurological *** treatment options are expensive,limited,and presently there are no approved cures for mucopolysaccharidoses typeⅢ***-associated virus gene therapy has significantly advanced the field forward,allowing researchers to successfully design,enhance,and improve potential *** group recently published an effective treatment using a codon-optimized triple mutant adeno-associated virus 8 vector that restores n-acetyl-alpha-glucosaminidase levels,auditory function,and lifespan in the murine model for mucopolysaccharidoses typeⅢB to that seen in healthy ***,we review the current state of the field in relation to the capsid landscape,adeno-associated virus gene therapy and its successes and challenges in the clinic,and how novel adenoassociated virus capsid designs have evolved research in the mucopolysaccharidoses typeⅢB field.

关键词： adeno-associated virus central nervous system gene therapy heparan sulfate immune response mucopolysaccharidoses type IIIB n-acetyl-alpha-glucosaminidase newborn screening

Comparison of Air Pollution−Mortality Associations Using Observed Particulate Matter Concentrations and Reanalysis data in 33 Spanish Cities

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Environment & Health 2024年第3期2卷 161-169页

作者： dominic royé Carmen Íñiguez Aurelio Tobías Climate Research Foundation 28003 MadridSpainSpanish Consortium for Research on Epidemiology and Public Health(CIBERESP)28029 MadridSpain Institute of Environmental Assessment and Water Research(IdAEA) Spanish Council for Scientific Research(CSIC)08034 BarcelonaSpain

Air pollution poses a health hazard in all ***,complete data on ambient particulate matter(PM)concentrations are not available in all world *** data is already a valuable source of exposure data in epidemiological studies examining the relationship between temperature and ***,the performance of reanalysis data in assessing the short-term health effects of particulate air pollution remains *** assessed the performance of CAMS reanalysis(EAC4)data from the European Centre for Medium-Range Weather Forecasts,compared with daily PM concentrations from field monitoring stations,to estimate short-term exposure to PM with an aerodynamic diameter less than 10μm(PM_(10))on daily mortality in 33 Spanish provincial capital cities using a two-stage time series regression *** shape of the PM_(10)distribution varied substantially between PM observations and CAMS global reanalysis of atmospheric composition(EAC4)reanalysis data,with correlation ranging from 0.21 to *** pooled mortality risk for a 10μg/m^(3)increase in PM_(10)showed similar estimates using PM concentrations{relative risks(RR)=1.007,95%confidence intervals(95%CI)=[1.002,1.011]}and EAC4 reanalysis data(RR=1.011,95%CI=[1.006,1.015]).However,the city-specific PM_(10)beta coefficients estimated using PM concentrations and EAC4 reanalysis data showed a low correlation(r=0.22).The use of reanalysis data should be approached with caution when assessing the association between particulate matter air pollution and health outcomes,particularly in cities with small populations.

关键词： Air pollution particulate matter PM_(10) reanalysis EAC4 mortality Spain time series regression

Effects of Periodically Inhomogeneous Birefringence on dark-Bright Vector Soliton Propagation and Interaction

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Chinese Physics Letters 2007年第2期24卷 462-464页

作者：李宏 d.n. Wang Hubei Key Laboratory of Bioanalytical Technique Hubei Normal University Huangshi 435002 School of Mechanical and Electronic Engineering Huangshi Institute of Technology Huangshi 435002 department of Electrical Engineering The Hong Kong Polytechnic University Hong Kong

The effects of periodically inhomogeneous birefringence on dark-bright vector soliton propagation and interaction are investigated by the numerical method. The birefringence leads to the submergence of the dark soliton and the disintegration of the bright soliton, and enhances the interaction between the neighbouring solitons. The system performance is determined by the bright soliton because the dark soliton has robust features. Finally, the avoidance and the effective control are introduced, and the controlling mechanism is demonstrated.

关键词： RAndOMLY VARYInG BIREFRInGEnCE OPTICAL SOLITOnS PERTURBATIOnS PARAMETERS FIBERS

Incorporating conceptual and interpretation uncertainty to mineral prospectivity modelling

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Geoscience Frontiers 2019年第4期10卷 1383-1396页

作者： j.n.Burkin M.d.Lindsay S.A.Occhipinti E.-j.Holden Centre for Exploration Targeting School of Earth SciencesThe University of Western Australia

Prospectivity analyses are used to reduce the exploration search space for locating areas prospective for mineral *** scale of a study and the type of mineral system associated with the deposit control the evidence layers used as proxies that represent critical ore genesis *** particular,knowledge-driven approaches(fuzzy logic)use a conceptual mineral systems model from which data proxies represent the critical *** typically vary based on the scale of study and the type of mineral system being *** analyses utilising interpreted data to represent proxies for a mineral system model inherit the subjectivity of the interpretations and the uncertainties of the evidence layers used in the *** the case study presented,the prospectivity for remobilised nickel sulphide(niS)in the west Kimberley,Western Australia,is assessed with two novel techniques that objectively grade interpretations and accommodate alternative mineralisation *** targets are then identified and supplied with a robustness assessment that reflects the variability of prospectivity value for each location when all models are *** first technique grades the strength of structural interpretations on an individual line-segment *** are obtained from an objective measure of feature evidence,which is the quantification of specific patterns in geophysical data that are considered to reveal underlying *** structures are weighted in the prospectivity model with grading values correlated to their feature *** technique allows interpreted features to contribute prospectivity proportional to their strength in feature evidence and indicates the level of associated stochastic *** second technique aims to embrace the systemic uncertainty of modelling complex mineral *** this approach,multiple prospectivity maps are each generated with different combinations of confidence values applied

关键词： Prospectivity Confidence Uncertainty Multiple models Mineral exploration nickel

Angiotensin-converting enzyme inhibitors from plants: A review of their diversity, modes of action, prospects, and concerns in the management of diabetes-centric complications

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journal of Integrative Medicine 2021年第6期19卷 478-492页

作者： Rakhi Chakraborty Swarnendu roy department of Botany A.P.C.Roy Government CollegeMatigara 734010West BengalIndia Plant Biochemistry Laboratory Department of BotanyUniversity of North BengalRaja Rammohunpur 734011West BengalIndia

Angiotensin-converting enzyme(ACE)inhibitors are antihypertensive medications often used in the treatment of diabetes-related *** ACE inhibitors are known to cause serious side effects like hypotension,renal insufficiency,and ***,there has been an intensifying search for natural ACE *** plants or plant-based extracts are known to possess ACEinhibitory *** this review,articles focusing on the natural ACE inhibitors extracted from plants were retrieved from databases like Google Scholar,Pub Med,Scopus,and Web of *** have found more than 50 plant species with ACE-inhibitory *** them,Angelica keiskei,Momordica charantia,Muntingia calabura,Prunus domestica,and Peperomia pellucida were the most potent,showing comparatively lower half-maximal inhibitory concentration *** the bioactive metabolites,peptides(e.g.,Tyr-Glu-Pro,Met-Arg-Trp,and Gln-Phe-Tyr-Ala-Val),phenolics(e.g.,cyanidin-3-Osambubioside and delphinidin-3-O-sambubioside),flavonoids([-]-epicatechin,astilbin,and eupatorin),terpenoids(ursolic acid and oleanolic acid)and alkaloids(berberine and harmaline)isolated from several plant and fungus species were found to possess significant ACE-inhibitory *** were also known to possess promising antioxidant,antidiabetic,antihyperlipidemic and anti-inflammatory *** the minimal side effects and lower toxicity of herbal compounds,development of antihypertensive drugs from these plant extracts or phytocompounds for the treatment of diabetesassociated complications is an important *** review,therefore,focuses on the ACE inhibitors extracted from different plant sources,their possible mechanisms of action,present status,and any safety concerns.

关键词： Angiotensin-converting enzyme Inhibitor Herbal medicine Hyperglycaemia Hypertension Bioactive metabolite