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journal of Materials Science & Technology 2014年第12期30卷 1296-1300页

作者： X.W.li l.Wang j.S.Dong l.H.lou Superalloys Division Institute of Metal Research Chinese Academy of Sciences

Evolution of the morphology of MC carbides with the change of cooling rate and carbon content in two kinds of nickel-base superalloys, K417 G and DD33, has been investigated. The morphology of MC carbides evolves from faceted to script-like with increasing cooling rate. Varying the carbon content from 40X10-6 to 320X10-6, the morphology of carbides changes from blocky, rod-like into script-like. Scanning electron microscopy observation of deep-etched samples indicates that these carbides evolve from octahedral to dendritic and then into welldeveloped dendrites accordingly in a three-dimensional manner. The morphology evolution is discussed from the viewpoint of the preferential growth orientation of fcc crystals and the carbide growth rate during directional solidification.

关键词： Carbides morphology Directional solidification Three-dimensional microstructure Nickel-base superalloys

Extravascular use of drug-eluting beads: A promising approach in compartment-based tumor therapy

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World journal of Gastroenterology 2013年第43期19卷 7586-7593页

作者： Simon Binder Andrew l lewis j-Matthias lhr Michael Keese Faculty of Medicine Mannheim University of Heidelberg68167 MannheimGermany Biocompatibles UK ltd. Department for Research and DevelopmentFarnham GU98QL SurreyUnited Kingdom Karolinska Institute Department of Clinical ScienceIntervention and Technology17177 StockholmSweden Clinic for Vascular and Endovascular Surgery University Hospital Frankfurt60590 Frankfurt am MainGermany

Intraperitoneal carcinomatosis(PC)may occur with several tumor *** prognosis of patients suffering from PC is usually *** treatment depends on the cancer entity and includes systemic chemotherapy,radiation therapy,hormonal therapy and surgical *** few patients may also benefit from hyperthermic intraperitoneal chemotherapy with a complete tumor *** therapies are often accompanied by severe systemic *** approach to reduce side effects is to target chemotherapeutic agents to the tumor with carrier *** experimental results have been achieved using drug-eluting beads(DEBs).A series of in vitro and in vitro experiments has been conducted to determine the suitability of their extravascular *** encapsulation devices were able to harbor CYP2B1producing cells and to shield them from the hosts immune system when injected *** this way ifosfamide-which is transformed into its active metabolites by CYP2B1-could be successfully targeted into pancreatic tumor *** DEBs can be used to target chemotherapeutics into the abdominal cavity for treatment of *** CYP2B1 producing cells are proven to be save for usage in man and if local toxic effects of chemotherapeutics can be controlled,DEBs will become promising tools in compartmentbased anticancer treatment.

关键词： Compartment based therapy Intraperitoneal Drug-eluting beads Carcinomatosis Hyperthermic intraperitoneal chemotherapy Glioblastoma Pancreatic cancer CYP2B1 Ifosfamide

Unexpected creep behavior in a rejuvenated metallic glass

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journal of Materials Science & Technology 2023年第32期163卷 140-149页

作者： j.P.Wu Y.lin F.H.Duan Q.Chen H.T.Wang N.li j.l.Wen j.Pan l.liu Shenyang National laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China State Key laboratory of Material Processing and Die&Mould Technology and School of Materials Science and Engineering Huazhong University of Science and TechnologyWuhan 430074China laboratory of Nanomaterials&Nanomechanics Department of Mechanical EngineeringCity University of Hong KongHong KongChina Wuhan National High Magnetic Field Center Huazhong University of Science and TechnologyWuhan 430074China Shenzhen Polytechnic Shenzhen 518055China

Rejuvenation,bringing metallic glasses(MGs)to the younger and higher energy states,provides an alternative avenue to explore the interplay between the property and microstructures of *** this study,the creep behavior of the Zr_(69.5)Cu_(12)Ni_(11)Al_(7.5)MGs was experimentally examined by controlling the energy state in terms of structural rejuvenation and thermal *** is found that compared to the as-cast counterpart,the annealed MG at a lower energy state exhibits a higher hardness,a smaller displacement,and a lower creep rate due to the decreased free volume and the inhibited activation of the shear transformation ***,the rejuvenated MG at a high energy state displays lower hardness and increased free volume content,yet it demonstrates superior creep resistance compared to its as-cast counterpart,which deviates from conventional *** unexpected phenomenon occurs as the initial high-content free volume annihilates during creep,and strain hardening takes precedence over strain softening as the prevailing process during creep deformation,leading to a superior creep performance in extremely rejuvenated MGs.

关键词： Metallic glass Energy state Rejuvenation Creep Strain-hardening

Fully Kinetic, Electromagnetic Particle-in-Cell Simulations of Plasma Microturbulence

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Communications in Computational Physics 2007年第4期2卷 684-722页

作者： j.l.V.lewandowski l.E.Zakharov Plasma Physics laboratory Princeton UniversityP.O.Box 451PrincetonNJ 08543USA.

A novel numerical method,based on physical intuition,for particle-in-cell simulations of electromagnetic plasma microturbulence with fully kinetic ion and electron dynamics is *** method is based on the observation that,for lowfrequency modes of interest[ω/ω_(ci)≪1,ωis the typical mode frequency andωci is the ion cyclotron frequency]the impact of particles that have velocities larger than the resonant velocity,v^(r)∼ω/k_(||)(k_(||) is the typical parallel wavenumber)is negligibly small(this is especially true for the electrons).Therefore it is natural to analytically segregate the electron response into an adiabatic response and a nonadiabatic response and to numerically resolve only the latter:this approach is termed the splitting ***,the exact separation between adiabatic and nonadiabatic responses implies that a set of coupled,nonlinear elliptic equations has to be solved;in this paper an iterative technique based on the multigrid method is used to resolve the apparent numerical *** is shown that the splitting scheme allows for clean,noise-free simulations of electromagnetic drift waves and ion temperature gradient(ITG)*** is also shown that the advantage of noise-free kinetic simulations translates into better energy conservation properties.

关键词： Plasma micro-turbulence particle-in-cell simulation multigrid solver.

PHOTOCURING STUDY OF NEW DENTAl RESINS BASED ON MUlTIFUNCTIONAl ACRYlIC ISOCYANURATE BY PHOTOCAlORIMETRY

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Chinese journal of Polymer Science 1999年第5期17卷 411-415页

作者：聂俊 l.A.linden j.F.Rabek Institute of Photographic Chemistry Chinese Academy of Sciences Beijing 100101 China Department of Dental Biomaterials Science Karolinska Institute S14104 Huddinge Stockholm

Photocuring of new dental resins composed of tri(2-hydroxyethyl) isocyanurate triacrylate (THITA) alone and its mixtures with trimethylolpropane triacrylate (TMPTA) or pentaerythritol triacrylate (PETA) initiated by camphorquinone/amine system was studied by photocalorimetry. Among several different amines as coinitiators, 2-ethyl-4-dimethylaminobenzoate (AM-3), N,N-dimethylbenzylamine (AM-5) and 2,4,6-[tri(dimethylaminomethyl)]phenol (AM-6) are most effective. Upon irradiation, photopolymerization can occur immediately and no induction period appears in N-2 nor in air. Comparing the THITA/TMPTA and THITA/PETA mixtures, the parameters of photopolymerization and hardness of photocured samples show a small difference and only change slightly with varying molar ratios of mixture. In the presence of inorganic filler, the hardness of photocuring resins is almost the same as that for commercial products.

关键词： multifunctional acrylates photocuring dental resin network

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon C.Daeschler Katelyn j.W.So Konstantin Feinberg Marina Manoraj jenny Cheung jennifer Zhang Kaveh Mirmoeini jPaul Santerre Tessa Gordon Gregory HBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

Soil Water Hysteresis at low Potential

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Pedosphere 2007年第4期17卷 436-444页

作者： l.PRUNTY j.BEll Department of Soil Science North Dakota State University FargoND 58105 (USA)

Knowledge of the soil water characteristic curve is fundamental for understanding unsaturated *** objective of this work was to find scanning hysteresis loops of two fine textured soils at water potentials below wilting *** was done by equilibration over NaCl solutions with water potentials of-6.6 to-18.8 MPa at 25℃.When cycled repeatedly through a series of potentials in the range noted previously both soils exhibited a hysteresis *** experimental differences in water content between the drying and wetting soils at the same water potential were much too large to be accounted for by failure to allow sufficient time to attain equilibrium as predicted by the exponential decay *** wetting versus drying differences were relatively small,however,at only 4 mg g-1 or less in absolute terms and about 3% of the mean of wetting and drying,in relative *** should be a consideration when modeling biological and physical soil processes at water contents below the wilting point,where small differences in water content result in large potential energy changes.

关键词： adsorption dry soil equilibration matric potential soil water characteristic

Strategies towards statistically robust interpretations of in situ U-Pb zircon geochronology

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Geoscience Frontiers 2016年第4期7卷 581-589页

作者： Christopher j.Spencer Christopher l.Kirkland Richard j.M.Taylor The Institute of Geoscience Research(TIGeR) Department of Applied GeologyWestern Australian School of MinesCurtin UniversityWA 6102Australia Centre for Exploration Targeting-Curtin Node Department of Applied GeologyWestern Australian School of MinesCurtin UniversityWA 6102Australia Australian Research Council Centre of Excellence for Core to Crust Fluid SystemsPerthWA 6102Australia

Zircon U-Pb geochronology has become a keystone tool across Earth science, arguably providing the gold standard in resolving deep geological time. The development of rapid in situ analysis of zircon （via laser ablation and secondary ionization mass spectrometry） has allowed for large amounts of data to be generated in a relatively short amount of time and such large volume datasets offer the ability to address a range of geological questions that would otherwise remain intractable （e.g. detrital zircons as a sedi- ment fingerprinting method）. The ease of acquisition, while bringing benefit to the Earth science com- munity, has also led to diverse interpretations of geochronological data. In this work we seek to refocus U -Pb zircon geochronology toward best practice by providing a robust statistically coherent workflow. We discuss a range of data filtering approaches and their inherent limitations （e.g. discordance and the reduced chi-squared; MSWD）. We evaluate appropriate mechanisms to calculate the most geologically appropriate age from both 238U/206pb and 207pb/206pb ratios and demonstrate the cross over position when chronometric power swaps between these ratios. As our in situ analytical techniques become progressively more precise, appropriate statistical handing of U-Pb datasets will become increasingly pertinent.

关键词： Zircon Geochronology U-Pb Geostatistics MSWD

On the Set of Grouplikes of a Coring

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Acta Mathematica Sinica,English Series 2012年第1期28卷 195-204页

作者： l.El KAOUTIT j.GóMEZ-TORRECIllAS Departamento de lgebra.Facultad de Educación y Humanidades Universidad de GranadaEl Greco No 10E-51002 CeutaEspaa Departamento de lgebra.Facultad de Ciencias Universidad de GranadaE18071 GranadaEspaa

We focus our attention to the set Gr（ξ） of grouplike elements of a coring ξover a ring A. We do some observations on the actions of the groups U（A） and Aut（ξ~） of units of A and of automorphisms of corings of ξ, respectively, on Gr（ξ）, and on the subset Gal（ξ）of all Galois grouplike elements. Among them, we give conditions on ξ under which Gal（ξ） is a group, in such a way that there is an exact sequence of groups {1} → U（Ag） → U（A） → Gal（ξ） → {1}, where Ag is the subalgebra of coinvaxiants for some g ∈ Gal（ξ）.

关键词： Galois corings division ring extensions non-abelian cohomology

Dual-energy X-ray absorptiometry scans accurately predict differing body fat content in live sheep

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journal of Animal Science and Biotechnology 2019年第1期10卷 248-253页

作者： David W Miller Ellen j Bennett joanne l Harrison Fiona Anderson Clare l Adam School of Veterinary and life Sciences Murdoch University Scotland’s Rural College (SRUC) Peter Wilson Building The Faculty of Health University of Tasmania School of Biological Sciences University of Aberdeen Rowett Institute of Nutrition and Health University of Aberdeen

Background: There is considerable interest in implementing mobile scanning technology for on-farm body composition analysis on live *** experiments evaluated the use of dual energy X-ray absorptiometry(DXA) as an accurate method of total body fat measurement in live ***: In Exp.1,visceral and whole body fat analysis was undertaken in sheep with body condition scores(BCS)in the range 2 to 3.25(scale 1: thin to 5: fat).The relationship of BCS was moderately correlated with visceral fat depot mass(r = 0.59,P le body fat(r = 0.70,P lood sampled to analyse circulating leptin concentrations,and were DXA scanned immediately post mortem for total body *** leptin concentrations had low correlations with BCS(r = 0.50,P lation with chemical body fat(r = 0.17,P > 0.05,n = 9).There was a moderate correlation between DXA body fat and BCS(r = 0.70,P ly correlated with chemical body fat(r = 0.81,P ls,was performed on growing sheep over a 32-week *** average BCS ranged from 2.39 ± 0.07(S.E.M.) to 3.05 ± 0.11 and the DXA body fat(%) ranged from 16.8 ± 0.8 to 24.2 ± *** was a moderate correlation between DXA body fat and BCS over the 32 weeks(r = 0.61,P lusions: Overall,these experiments indicated that there was good agreement between BCS,DXA and chemical analysis for measuring total body fat in sheep,and that DXA scanning is a valid method for longitudinal measurement of total body fat in live sheep.

关键词： BCS DEXA Fat leptin longitudinal Sheep