检索结果-南通市图书馆

维普期刊数据库

慢性阻塞性肺疾病:应用双能量氙通气cT技术的定量与可视化通气模式分析

在线全文

学校读者我要写书评

暂无评论

国际医学放射学杂志 2010年第6期 569-570页

作者： E.A.park j.m.goo s.j.park h.j.lee c.h.lee c.m.park 张晓东 Department of Radiology Seoul National University Hospital seoul National University college of medicine 101 DaehangnoJongno-guSeoul 110-744Korea

目的评价氙通气cT对于慢性阻塞性肺疾病的定量与可视化分析的潜力。材料与方法本研究获得医院伦理委员会认可。签署知情同意书后,32例慢性阻塞性肺疾病病

关键词：慢性阻塞性肺疾病可视化分析氙气 cT

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

hyundai公司新一代1.8L汽油机

汽车与新动力 2012年第2期 7-13页

作者： cho j m Yoon Y D lee j s kim h c 戴朝典

hyundai公司开发出1款新型1.8 L汽油机,以替代紧凑型及中型轿车上的老机型。该汽油机首次被配装在2011年亮相北美市场的hyundai公司新款Elantra汽车上。通过应用双连续可变气门正时系统,以及能获得中、低速大扭矩和高速大功率的两级可... 详细信息

hyundai公司开发出1款新型1.8 L汽油机,以替代紧凑型及中型轿车上的老机型。该汽油机首次被配装在2011年亮相北美市场的hyundai公司新款Elantra汽车上。通过应用双连续可变气门正时系统,以及能获得中、低速大扭矩和高速大功率的两级可变进气系统,这一新机型实现了高动力性能和低燃油耗。此外,优化了下部结构件和进气系统零部件,与此同时,也十分重视减轻部件质量,以降低噪声水平。该汽油机符合美国特超低排放车和欧5排放法规。简要介绍了新一代1.8 L直列4缸汽油机(Nu汽油机),以及为提高动力性能、减少燃油耗、降低排放和振动噪声而采取的各种相关技术。

关键词：汽油机连续可变气门正时系统可变进气系统偏置曲轴交流发电机超速解耦器

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

mR扩散加权成像在壶腹癌诊断中的附加价值

国际医学放射学杂志 2013年第2期 171-172页

作者： k.m. jang s.h. kim s.j. lee h.j. park D. choi j. hwang 郭凌飞 Department of Radiology and center for Imaging science Samsung Medical Center Sungkyunkwan University School of Medicine 50 Ilwon-dong Gangnam-gu Seoul 135-710 Korea

目的评估在常规mR成像中扩散加权成像对壶腹癌诊断的附加价值。材料与方法该项回顾性研究获得了机构伦理委员会批准并免签知情同意书。纳入恶性壶腹部梗阻病人23例、良性壶腹部梗阻病人39例。根据所见的十二指肠乳头或其预估的位置进行... 详细信息

目的评估在常规mR成像中扩散加权成像对壶腹癌诊断的附加价值。材料与方法该项回顾性研究获得了机构伦理委员会批准并免签知情同意书。纳入恶性壶腹部梗阻病人23例、良性壶腹部梗阻病人39例。根据所见的十二指肠乳头或其预估的位置进行定性（信号强度,强化类型）或定量[表观扩散系数（ADc）]分析。两名观察者独立地对常规mR成像和随后的常规与扩散加权联合的影像进行评估。采用五点评估法对壶腹癌的可能性进行评估。使用Fisher确切概率法和mann-WhitneyU检验对两组间进行比较。对诊断性能（受试者操作特征曲线）、精确度、敏感度、特异度、阳性预测值（PPV）、阴性预测值（NPV）进行评估。结果在常规mR成像中,良性组内可见的或预计的十二指肠乳头所在区域表现为等信号（39例中有27;8例,占69%;7%）,增强类型与正常十二指肠壁（39例中有27例,占69%）相似。上述表现良性组比恶性组（23例中有7;8例,占30%;8%）和常规mR成像组（23例中检出了3例,占13%）更常见。在扩散加权成像中,23例中有21例（91%）壶腹癌显示为高信号,而全部良性病例与正常十二指肠壁比较均表现为等信号（Pc值（1.23×10-3mm2/s）显著低于良性组（1.69×10-3mm2/s）(Pc曲线下面积（Az）]在增加了扩散加权成像后显著提高。观察者1的Az提高至0.923;.992（P=0.029）,观察者2的Az提高至0.910;.992（P=0.025）。此外,联合应用常规mRI与扩散加权成像的诊断精确度、敏感度、特异度、阳性预测值（PPV）、阴性预测值（NPV）显著高于单独应用常规mRI。结论与常规的mRI比较,常规mRI与扩散加权成像联合应用可以显著提高壶腹癌的检测率。

关键词：壶腹癌常规 mR 加权成像附加价值

高阶成像参数可改善T2/FLAIR不匹配征预测弥漫性低级别胶质瘤亚型即IDh突变与无1p19q共缺失的价值

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2020年第2期 249-249页

作者： m.k.lee j.E.park Y.jo s.Y.park s.j.kim h.s.kim 冀晓莉 Department of Radiology and Research Institute of Radiology Asan Medical Center University of Ulsan College of Medicine

目的 T2/FLAIR不匹配征与高阶影像学参数结合可提高对弥漫性低级别胶质瘤分子亚型的判断能力。本研究评价表观扩散系数(ADc)、脑血容量(cBV)对T2/FLAIR不匹

关键词： T2/FLAIR cBV ADc AUc 低级别胶质瘤成像参数弥漫性 IDh

对化疗耐受非小细胞肺癌的突变分析而进行的重复活检:充分性和并发症

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2013年第1期 80-81页

作者： h.j.Yoon h.Y.lee k.s.lee Y.choi m.Ahn k.park 柴超 Department of Radiology and center for Imaging science Samsung Medical CenterSungkyunkwan University School of Medicine50 Ilwon-DongKangnam-KuSeoul 135-710Korea

目的对于先前化疗耐受的非小细胞肺癌病人,评价为突变分析而进行重复活检的可行性和安全性。材料与方法这项前瞻性研究获得单位伦理委员会批准,并取得所有病人的知情同意书。选择126例对常规化疗或表皮生长因子受体(EgFR)-酪氨酸激酶抑... 详细信息

目的对于先前化疗耐受的非小细胞肺癌病人,评价为突变分析而进行重复活检的可行性和安全性。材料与方法这项前瞻性研究获得单位伦理委员会批准,并取得所有病人的知情同意书。选择126例对常规化疗或表皮生长因子受体(EgFR)-酪氨酸激酶抑制剂耐受的非小细胞肺癌病人,对其中94例病人[男31例,女63例,(57±10.3)岁]进行重复活检。32例病人在严格观察胸部cT影像后因各种原因被排除。采用c臂锥形束cT导向进行经皮胸穿肺活检。评价重复活检的技术成功率和进行突变分析的标本充足率。记录任何与活检相关的并发症。结果活检的技术成功率为100%。94例病人中的75例(80%)标本已足以进行突变分析。75例标本中,35例进行了EgFR突变检测,34例进行了间变性淋巴瘤激酶(ALk)基因重组检测,6例两者都进行。结果显示,20例EgFR光敏突变(外显子19或21)为阳性,5例出现EgFRT790m突变,而11例发现间变性淋巴瘤激酶基因重组。94例病人中13例(14%)出现术后并发症。结论当采用严格的cT标准进行操作时,对先前进行化疗的非小细胞肺癌病人进行突变分析时,重复活检是可行的,大约4/5的病人样品足够进行基因分析,而并发症的发生率可以接受。

关键词：化疗耐受突变分析标本基因重组肺癌病人间变性淋巴瘤激酶并发症并发病疾病

R&D of back-end electronics for improved resistive plate chambers for the phase 2 upgrade of the cms end-capmuon system

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Radiation Detection Technology and methods 2022年第3期6卷 306-316页

作者： h.kou Z.-A.Liu j.Zhao j.song Q.hou W.Diao P.cao W.gong N.Wang A.samalan m.Tytgat m.El sawy g.A.Alves F.marujo E.A.coelho F.Torres Da silva De Araujo E.m.Da costa h.Nogima A.santoro s.Fonseca De souza D.De jesus Damiao m.Thiel m.Barroso Ferreira Filho k.mota Amarilo A.Aleksandrov R.hadjiiska P.Iaydjiev m.Rodozov m.shopova g.sultanov A.Dimitrov L.Litov B.Pavlov P.Petkov A.Petrov E.shumka s.j.Qian c.Avila D.Barbosa A.cabrera A.Florez j.Fraga j.Reyes Y.Assran m.A.mahmoud Y.mohammed I.Laktineh g.grenier m.gouzevitch L.mirabito k.shchablo c.combaret W.Tromeur g.galbit A.Luciol X.chen I.Bagaturia I.Lomidze Z.Tsamalaidze V.Amoozegar B.Boghrati m.Ebraimi E.Zareian m.mohammadi Najafabadi m.Abbrescia g.Iaselli g.Pugliese F.Loddo N.De Filippis R.Aly D.Ramos W.Elmetenawee s.Leszki I.margjeka D.Paesani L.Benussi s.Bianco D.Piccolo s.meola s.Buontempo F.carnevali L.Lista P.Paolucci F.Fienga A.Braghieri P.salvini P.montagna c.Riccardi P.Vitulo E.Asilar j.choi T.j.kim s.Y.choi B.hong k.s.lee h.Y.Oh j.goh I.Yu c.Uribe Estrada I.Pedraza h.castilla-Valdez R.L.Fernandez A.sanchez-hernandez E.Vazquez m.Ramirez-garcia N.Zaganidis A.Radi h.hoorani s.muhammad A.Ahmad I.Asghar m.A.shah W.A.khan j.Eysermans I.crotty on behalf of the cms muon group Department of Physics and Astronomy Ghent UniversityProeftuinstraat 869000 GhentBelgium UniversitéLibre de Bruxelles Avenue Franklin Roosevelt50-1050 BruxellesBelgium centro Brasileiro Pesquisas Fisicas R.Dr.Xavier Sigaud150UrcaRio de JaneiroRio de Janeiro 22290-180Brazil Department de Fisica Nuclear e Altas Energias Instituto de FisicaUniversidade do Estado do Rio de JaneiroRua Sao Francisco Xavier524Rio de JaneiroRio de Janeiro 20559-900Brazil Bulgarian Academy of sciences Institute for Nuclear Researches and Nuclear EnergyTzarigradsko Shaussee Boulevard 721784 SofiaBulgaria Faculty of Physics University of Sofia5 James Bourchier Boulevard1164 SofiaBulgaria school of Physics Peking UniversityBeijing 100871China state key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of chinese Academy of sciences B325Main BuildingNo.19(A)Yuquan RoadShijingshan DistrictBeijing 100049China Universidad de Los Andes Carrera 1No.18A-12BogotáColombia Egyptian Network for high Energy Physics Academy of Scientific Research and Technology101 Kasr El-Einy St.CairoEgypt suez University SuezCairo RoadElsalam CitySuez 43522Egypt center for high Energy Physics(chEP-FU) Faculty of ScienceFayoum UniversityEl-Fayoum 63514Egypt Univ Lyon Univ Claude Bernard Lyon 1CNRS/IN2P3IP2I LyonUMR 582269622 VilleurbanneFrance georgian Technical University 77 Kostava Str.0175 TbilisiGeorgia school of Particles and Accelerators Institute for Research in Fundamental Sciences(IPM)P.O.Box 19395-5531 TehranIran school of Engineering Damghan UniversityDamghan ***Iran INFN Sezione di BariVia Orabona 470126 BariItaly INFN Laboratori Nazionali di Frascati(LNF)Via Enrico Fermi 4000044 FrascatiItaly INFN Sezione di NapoliComplesso University Monte S.AngeloVia Cintia80126 NapoliItaly Dipartimento di Ingegneria Elettrica e delle Tecnologie dell’Informazione UniversitàDegli Studi di Napoli Federico II80126 NapoliI

Purpose The Large hadron collider(Lhc)at European Organization for Nuclear Research is planned to be upgraded to the high luminosity *** the luminosity makes muon triggering reliable and ofﬂine reconstruction very *** enhance the redundancy of the compact muon solenoid(cms)muon system and resolve the ambiguity of track reconstruction in the forward region,an improved Resistive Plate chamber(iRPc)with excellent time resolution will be installed in the Phase-2 cms *** iRPc will be equipped with Front-End Electronics(FEE),which can perform high-precision time measurements of signals from both ends of the *** Back-End Electronics(BEE)need to be researched and developed to provide sophisticated functionalities such as interacting with FEE with shared links for fast,slow control(sc)and data,in addition to trigger primitives(TPs)generation and data acquisition(DAQ).method The BEE prototype uses a homemade hardware board compatible with the mTcA standard,the back-end board(BEB).BEE interacts with FEE via a bidirectional 4.8 gbps optical paired-link that integrates clock,data,and control *** clock and fast/slow control commands are distributed from BEB to the FEE via the *** uplink is used for BEB to receive the time information of the iRPc’sﬁred strips and the responses to the fast/slow control *** have a pipelined detector data for clusterﬁnding operation,recover(Demux)the time relationship of which is changed due to the transmission protocol for the continuous incoming mUXed data from *** at each bunch crossing(BX),clusteringﬁred strips that satisfy time and spatial constraints to generate *** incoming raw mUXed detector data and TPs in a time window and latency based on the trigger signal are read out to the DAQ *** Ethernet(gbE)of siTcP and commercial 10-gbE are used as link standards for sc and DAQ,respectively,for the BEB to interact with the *** The joint test results of

关键词： cms iRPc BEE TP DAQ sc

Development of an Inverter system for korean 750-kWgearless Pm synchronous Wind Turbine

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Development of an Inverter System for Korean 750-kWGearless ...

Ambivalent response in pathogen defense: A double-edged sword?

The 3～(rd) World Wind Energy conference & Renewable Energy Exhibition the 2nd Wind Power Asia

作者： j. s. Oh Y. g. son j. h. suh s. j. kwon W. W. lee D. E. kim c. W. chung k. s. han j. s. hwang j. Y. Ryu O. j. kwon g. W. park h. j. kim PoWER-c/PAL POSTECH San 31 Hyojadong Namgu 790-784 Pohang Korea PoWER-c/PAL POSTECH San 31 Hyojadong Namgu 790-784 Pohang Korea PoWER-c/PAL POSTECH San 31 Hyojadong Namgu 790-784 Pohang Korea PoWER-c/PAL POSTECH San 31 Hyojadong Namgu 790-784 Pohang Korea PoWER-c/PAL POSTECH San 31 Hyojadong Namgu 790-784 Pohang Korea PoWER-c/PAL POSTECH San 31 Hyojadong Namgu 790-784 Pohang Korea PoWER-c/PAL POSTECH San 31 Hyojadong Namgu 790-784 Pohang Korea PoWER-c/PAL POSTECH San 31 Hyojadong Namgu 790-784 Pohang Korea Unison co. LTD 803 Jangsan-ri Sooshin-myun Cheonan City Chung-nam Korea Unison co. LTD 803 Jangsan-ri Sooshin-myun Cheonan City Chung-nam Korea PLAsPO co. LTD 1005 Ilsan Techno Town Baekseok-dong Ilsan-gu Gyeonggi-do Korea PLAsPO co. LTD 1005 Ilsan Techno Town Baekseok-dong Ilsan-gu Gyeonggi-do Korea PLAsPO co. LTD 1005 Ilsan Techno Town Baekseok-dong Ilsan-gu Gyeonggi-do Korea

Wind turbines require an electromechanical converter in order to convert the rotary motion of the blades into electrical power. The converter system is connected to between a generator system and a

关键词： kW Inverter system Permanent magnet (Pm) IgBT Based Electronic converters

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Plant communications 2022年第6期3卷 190-207页

作者： chi-Yeol kim hyeunjeong song Yong-hwan lee Department of Agricultural Biotechnology Seoul National UniversitySeoul 08826Korea Plant Immunity Research center Seoul National UniversitySeoul 08826Korea Research Institute of Agriculture and Life sciences Seoul National UniversitySeoul 08826Korea Interdisciplinary Program in Agricultural genomics Seoul National UniversitySeoul 08826Korea center for Fungal genetic Resources Seoul National UniversitySeoul 08826Korea

Plants possess effective immune systems that defend against most microbial *** plant immunity research has focused on the classic binary defense model involving the pivotal role of small-molecule hormones in regulating the plant defense signaling *** most of our current understanding comes from studies that relied on information derived from a limited number of pathosystems,newer studies concerning the incredibly diverse interactions between plants and microbes are providing additional insights into other novel ***,we review the roles of both classical and more recently identified components of defense signaling pathways and stress hormones in regulating the ambivalence effect during responses to diverse *** of their different lifestyles,effective defense against biotrophic pathogens normally leads to increased susceptibility to necrotrophs,and vice *** these opposing forces,the plant potentially faces a trade-off when it mounts resistance to a specific pathogen,a phenomenon referred to here as the ambivalence *** also highlight a novel mechanism by which translational control of the proteins involved in the ambivalence effect can be used to engineer durable and broad-spectrum disease resistance,regardless of the lifestyle of the invading pathogen.

关键词： ambivalence effect crop protection hormone crosstalk pathogen plant defense susceptibility(s)gene

Regulation of c-smAc formation and AkT-mTOR signaling by the Tsg101-IFT20 axis in cD4^(+)T cells

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

cellular & molecular Immunology 2023年第5期20卷 525-539页

作者： jiung jeong In kang Yumin kim keun Bon ku jang hyun park hyun-jin kim chae Won kim jeongwoo La hi Eun jung hyeon cheol kim Young joon choi jaeho kim joon kim heung kyu lee graduate school of medical science and Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Department of Internal medicine Seoul National University HospitalSeoul 03080Republic of Korea Department of Biological sciences KAISTDaejeon 34141Republic of Korea Department of convergent Research of Emerging Virus Infection Korea Research Institute of Chemical TechnologyDaejeon 34114Republic of Korea.

cD4^(+)T cells play major roles in the adaptive immune system,which requires antigen recognition,costimulation,and cytokines for its elaborate *** studies have provided new insight into the importance of the supramolecular activation cluster(smAc),which comprises concentric circles and is involved in the amplification of cD4^(+)T cell ***,the underlying mechanism of smAc formation remains poorly ***,we performed single-cell RNA sequencing of cD4^(+)T cells left unstimulated and stimulated with anti-cD3 and anti-cD28 antibodies to identify novel proteins involved in their *** found that intraflagellar transport 20(IFT20),previously known as cilia-forming protein,was upregulated in antibody-stimulated cD4^(+)T cells compared to unstimulated cD4^(+)T *** also found that IFT20 interacted with tumor susceptibility gene 101(Tsg101),a protein that endocytoses ubiquitinated T-cell *** interaction between IFT20 and Tsg101 promoted smAc formation,which led to amplification of AkT-mTOR ***,IFT20-deficient cD4^(+)T cells showed smAc malformation,resulting in reduced cD4^(+)T cell proliferation,aerobic glycolysis,and cellular ***,mice with T-cell-specific IFT20 deficiency exhibited reduced allergen-induced airway ***,our data suggest that the IFT20-Tsg101 axis regulates AkT-mTOR signaling via smAc formation.

关键词： cD4^(+)T cell Intraflagellar transport 20 Tumor susceptibility gene 101 AkT-mTOR signaling Asthma supramolecular activation cluster