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Large-scale interplant exchange of macromolecules between soybean and dodder under nutrient stresses

Plant Diversity 2024年第1期46卷 116-125页

作者： jingxiong Zhang Shalan Li Wenxing Li Zerui Feng Shuhan Zhang Xijie Zheng Yuxing Xu Guojing Shen Man Zhao Guoyan cao Xuna Wu jianqiang Wu Department of Economic Plants and Biotechnology Yunnan Key Laboratory for Wild Plant ResourcesKunming Institute of BotanyChinese Academy of SciencesKunming 650201China CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Conservation and Utilization of Bio-Resources in Yunnan and Center for Life Science School of Life SciencesYunnan UniversityKunming 650500China

Parasitic plants and their hosts communicate through haustorial *** deficiency is a common stress for plants,yet little is known about whether and how host plants and parasites communicate during adaptation to such nutrient *** this study,we used transcriptomics and proteomics to analyze how soybean(Glycine max)and its parasitizing dodder(Cuscuta australis)respond to nitrate and phosphate deficiency(-N and-P).After-N and-P treatment,the soybean and dodder plants exhibited substantial changes of transcriptome and proteome,although soybean plants showed very few transcriptional responses to-P and dodder did not show any transcriptional changes to either-N ***,large-scale interplant transport of mRNAs and proteins was *** the mobile mRNAs only comprised at most 0.2%of the transcriptomes,the foreign mobile proteins could reach 6.8%of the total proteins,suggesting that proteins may be the major forms of interplant ***,the interplant mobility of macromolecules was specifically affected by the nutrient regimes and the transport of these macromolecules was very likely independently *** study provides new insight into the communication between host plants and parasites under stress conditions.

关键词： Cuscuta Mobile molecules Nutrient deficiency Host plant-parasitic plant interaction Interplant transport Systemic signaling

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Hyphae-mediated bioassembly of carbon fibers derivatives for advanced battery energy storage

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Carbon Energy 2024年第6期6卷 140-150页

作者： Lei Huang Zhong Qiu Ping Liu Xinhui Xia Feng cao Xinping He Chen Wang Wangjun Wan Yongqi Zhang Yang Xia Wenkui Zhang Minghua Chen jiancang Zhou Department of Critical Care Medicine Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhouChina State Key Laboratory of Silicon Materials Key Laboratory of Advanced Materials and Applications for Batteries of Zhejiang ProvinceSchool of Materials Science&EngineeringZhejiang UniversityHangzhouChina College of Materials Science&Engineering Zhejiang University of TechnologyHangzhouChina State Key Laboratory of Photocatalysis on Energy and Environment Fuzhou UniversityFuzhouChina Department of Engineering Technology Huzhou CollegeHuzhouChina Zhejiang Academy of Science and Technology for Inspection&Quarantine HangzhouZhejiangChina Institute of Fundamental and Frontier Science University of Electronic Science and Technology of ChinaChengduChina Key Laboratory of Engineering Dielectric and Applications(Ministry of Education) School of Electrical and Electronic EngineeringHarbin University of Science and TechnologyHarbinChina

Ingenious design and fabrication of advanced carbon-based sulfur cathodes are extremely important to the development of high-energy lithium-sulfur batteries,which hold promise as the next-generation power ***,for the first time,we report a novel versatile hyphae-mediated biological assembly technology to achieve scale production of hyphae carbon fibers(HCFs)derivatives,in which different components including carbon,metal compounds,and semiconductors can be homogeneously assembled with HCFs to form composite *** mechanism of biological adsorption assembly is also *** a representative,reduced graphene oxides(rGOs)decorated with hollow carbon spheres(HCSs)successfully co-assemble with HCFs to form HCSs@rGOs/HCFs hosts for sulfur *** this unique architecture,not only large accommodation space for sulfur but also restrained volume expansion and fast charge transport paths are ***,multiscale physical barriers plus chemisorption sites are simultaneously established to anchor soluble lithium ***,the designed HCSs@rGOs/HCFs-S cathodes deliver a high capacity(1189 mA h g^(-1)at 0.1 C)and good high-rate capability(686 mA h g^(-1)at 5 C).Our work provides a new approach for the preparation of high-performance carbon-based electrodes for energy storage devices.

关键词： bioassembly carbon fibers energy storage graphene lithium-sulfur batteries

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Isotropic volumetric MRI for displaying cranial perineural spread of cranial nerve in nasopharyngeal carcinoma

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中国医学影像技术 2024年第8期40卷 1164-1169页

作者： ZHENG Dechun XU Shugui LAI Guojing HU Chunmiao cao Xisheng FENG Meimei PENG Li Department of Radiology Clinical Oncology School of Fujian Medical UniversityFujian Cancer HospitalFuzhou 350014China Department of Radiation Oncology Clinical Oncology School of Fujian Medical UniversityFujian Cancer HospitalFuzhou 350014China

Objective To observe the value of isotropic volumetric MRI for displaying perineural spread(PNS)of cranial nerve(CN)in nasopharyngeal *** Eighty-seven patients with pathologically proven nasopharyngeal carcinoma were prospectively *** scanning,including three-dimensional liver acquisition with volume acceleration-flexible(3D LAVA_Flex)image,T2WI with fat suppression(T2WI-FS),T1WI,contrast enhancement(CE)T1WI-FS of nasopharynx and neck region were *** displaying rates of CN PNS were evaluated and compared between 3D LAVA_Flex and T2WI-FS,T1WI,CE-T1WI-FS at patient level,CN group level and neural level,*** The displaying rate of CN PNS in all 87 nasopharyngeal carcinoma patients by 3D LAVA_Flex sequence was 49.43%(43/87),higher than that of conventional MRI(30/87,34.48%,P=0.001).Among 59 patients with advanced nasopharyngeal carcinoma diagnosed with conventional sequences,the displaying rate of CN PNS was 71.19%(42/59)by 3D LAVA-Flex sequence,higher than that of conventional MRI(30/59,50.85%,P=0.001).At both patient level and posterior CN level,significant differences of the displaying rate of CN PNS were found between 3D LAVA-Flex sequence and T2WI-FS,T1WI,CE-T1WI-FS,while at CN level,the displaying rates of mandibular nerve PNS,CNⅨ—ⅪPNS in jugular foramen(P<0.05)and CNⅨ—ⅫPNS in carotid space of 3D LAVA_Flex sequence were all significantly higher than that of T2WI-FS,T1WI and CE-T1WI-FS(all P<0.05),of PNS of CNⅢ—Ⅴin cavernous sinus were higher than that of T2WI-FS(P<0.05),while of PNS of hypoglossal nerve were significantly higher than that of T2WI-FS and T1WI(both P<0.05).Conclusion 3D LAVA_Flex sequence could be used to effectively display CN PNS of nasopharyngeal carcinoma.

关键词： nasopharyngeal neoplasm cranial nerve magnetic resonance imaging neoplasm metastasis prospective studies

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复杂固-液介质的速度应力方程三角形单元间断伽辽金地震波模拟算法

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地球物理学报 2024年第2期67卷 684-695页

作者：曹文忠张伟中国地震局地球物理研究所北京100081 南方科技大学地球与空间科学系广东深圳518055

间断伽辽金法可用于存在复杂边界条件的模型,同时具有高阶精度和易于并行计算的优点,因此近年来在地震波传播模拟研究中得到了快速发展.数值通量是间断伽辽金法的关键组成部分之一.相比于其他通量,基于Rankine-Hugoniot跳跃条件的通量(R... 详细信息

间断伽辽金法可用于存在复杂边界条件的模型,同时具有高阶精度和易于并行计算的优点,因此近年来在地震波传播模拟研究中得到了快速发展.数值通量是间断伽辽金法的关键组成部分之一.相比于其他通量,基于Rankine-Hugoniot跳跃条件的通量(RH-condition通量)在固体和液体介质边界具有更宽的稳定性,可以使用更大的时间步长,尤其是液体和固体之间的波阻抗差异较大时.它已被用于基于四边形网格和速度-应变方程的间断伽辽金地震波固液介质模拟.本文为了模拟陆地自然水体等存在复杂固-液界面形状的地震波传播,并在未来与其他数值方法耦合,发展了基于三角形网格的RH-condition通量间断伽辽金方法,使用一阶速度-压力声波和一阶速度-应力弹性波方程模拟复杂固-液介质中地震波的传播.通过水平层状和sin型起伏固-液模型,验证了该方法模拟结果的准确性.通过数值模拟展示了所提出的间断伽辽金法在不同网格大小和阶数下的准确性和效率.最后通过一个复杂模型的例子表明存在复杂固-液界面时该方法可以准确施加固-液边界条件.

关键词：间断伽辽金地震波模拟固-液介质数值通量

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Stromal cell decidualization and embryo implantation: a vulnerable step leading to successful pregnancy

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Reproductive and Developmental Medicine 2024年第2期8卷 101-110页

作者： Luhan jiang Sudini R.Fernando Suranga P.Kodithuwakku Dandan cao William S.B.Yeung Kai-Fai Lee Department of Obstetrics and Gynaecology School of Clinical MedicineLKS Faculty of MedicineThe University of Hong KongHong Kong SAR 999077China Department of Animal Science Faculty of Animal Science&Export AgricultureUva Wellassa UniversityBadulla 50000Sri Lanka Department of Animal Science Faculty of AgricultureUniversity of PeradeniyaPeradeniya 20400Sri Lanka Shenzhen Key Laboratory of Fertility Regulation.The University of Hong Kong-Shenzhen Hospital Shenzhen 518053China

Endometrial stromal cell decidualization is a crucial step in endometrial remodeling during *** is controlled by orchestrated ovarian hormones,followed by the activation of various downstream signaling *** evidence has shown multiple functions of decidualized endometrial stromal cells during embryo implantation,including tissue remodeling,antioxidative stress,angiogenesis,and immune *** distinct secretomes of decidualized stromal cells also reveal their intensive interactions with epithelial,endothelial,and immune ***,aberrant decidualization leads to pregnancy failures,such as recurrent pregnancy loss and repeated implantation *** review aimed to provide an overview of the molecular mechanisms underlying the divergent functions of decidualized endometrial stromal cells and their potential clinical ***,the use of single-cell RNA sequencing data further enhances our understanding of these biological *** review discusses decidualization-related signaling pathways that serve as potential therapeutic targets for treating implantation failure in in vitro fertilization and provides novel approaches to investigate the underlying causes of female infertility.

关键词： Endometrial stromal cell Decidualization Embryo implantation Recurrent pregnancy loss Repeated implantation failure

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Different people,different wild:Comparing and mapping wilderness representation in Wuyishan National Park,China

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Geography and Sustainability 2024年第1期5卷 144-156页

作者： Aifang Weng Lingyun Liao Yue cao Steve Carver Li Lin Siyuan Shen Zhengduo Xu jianwen Dong Siren Lan Rui Yang College of Landscape Architecture and Art Fujian Agriculture and Forestry UniversityFuzhou 350002China College of Geographical Science Fujian Normal UniversityFuzhou 350117China Institute of Wuyishan National Park Fuzhou 350002China Department of Landscape Architecture School of ArchitectureTsinghua UniversityBeijing 100084China Institute for National Parks Tsinghua UniversityBeijing 100084China Wildland Research Institute School of GeographyUniversity of LeedsLeedsUK

It is essential to better integrate wilderness representations of different stakeholders into wilderness *** way in which local residents and other stakeholders frame the construction of wilderness of protected areas in developing countries are poorly *** these areas,land use policy and decision may lead to *** study aims to explore existing public wilderness representations using a questionnaire survey(n=514)administered amongst tourists and other stakeholders in the Wuyishan National Park,in southeast *** spatial differences in public representations of wilderness across different stakeholder groups were compared against expert *** found that integrated wilderness representation maps of different stakeholder groups were consistent,namely'area where wild animals live','area with no human influence','a barren and lonely area'.However,three sub-representations of the individual stakeholders varied ***,expert-based wilderness mapping did not reflect public representations accurately,and an integrated wilder-ness quality map considering wilderness representations across both stakeholders and experts can better identify detailed wilderness *** study provides new insights and technical support for future exploration of wilder-ness conservation and mapping in China and other countries with insufficient awareness of wilderness values and investigations in a regional scale.

关键词： Wilderness mapping Public participation Environment perception Protected areas

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Nanomedicine integrating the lipidic derivative of 5-fluorouracil,miriplatin and PD-L1 si RNA for enhancing tumor therapy

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Chinese Chemical Letters 2024年第6期35卷 385-391页

作者： An Lu Yuhao Guo Yi Yan Lin Zhai Xiangyu Wang Weiran cao Zijie Li Zhixia Zhao Yujie Shi Yuanjun Zhu Xiaoyan Liu Huining He Zhiyu Wang jian-Cheng Wang Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems State Key Laboratory of Natural and Biomimetic DrugsSchool of Pharmaceutical SciencesPeking UniversityBeijing 100191China Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics School of PharmacyTianjin Medical UniversityTianjin 300070China Department of Immuno-oncology The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011China Department of Pharmacy Clinical Trial Research CenterChina-Japan Friendship HospitalBeijing 100029China Laboratory of innovative formulations and pharmaceutical excipients Ningbo Institute of Marine MedicinePeking UniversityNingbo 315832China

Immunosuppressive microenvironments present critical problems in clinical *** regulate the tumor immune microenvironment for enhancing antitumor effect,a combination of immune checkpoint inhibitors(ICIs)with chemotherapeutics has been applied *** this study,miriplatin(MiPt),the lipidic derivative of 5-fluorouracil(Fu-OA),as well as the programmed death ligand 1(PD-L1)target si RNA(siPD-L1)were integrated into Lip-Pt/Fu@siPD-L1 nanoparticles(NPs)for *** vitro results showed that Lip-Pt/Fu@siPD-L1 NPs could exhibit effective siRNA gene silencing and promote the phagocytosis of tumor cells by ***,in vivo results revealed that LipPt/Fu@siPD-L1 NPs showed significantly higher anti-tumor efficiency than that of the physical mixing of Mi Pt,5-fluorouracil,and Lip@siPD-L1 NPs(delivery of siPD-L1 by liposomes).The best anti-tumor efficiency of Lip-Pt/Fu@siPD-L1 NPs resulted from the synergistic immunotherapeutic effects of Mi Pt and siPD-L1 based on the inhibition of CD47 expression and the downregulation of PD-L1 in tumor cells,which elicited a robust anti-tumor immune response through the activation of macrophage phagocytosis and immune checkpoint *** Lip-Pt/Fu@siPD-L1 NPs provide a potential strategy for tumor chemo-immunotherapy.

关键词： Chemo-immunotherapy Immune checkpoint inhibition Gene silencing Miriplatin Macrophage phagocytosis Nanotechnology

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基于B样条曲线的心轨重构廓形参数影响分析

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西南交通大学学报 2024年第2期59卷 264-272页

作者：赵卫华曹洋福建理工大学土木工程学院福建福州350118 福建理工大学地下工程福建省高校重点实验室福建福州350118 福州大学土木工程学院福建福州350108

针对固定辙叉钢轨廓形不规则变化特点,基于B样条理论提出一种考虑固定辙叉钢轨断面廓形特征的参数化设计方法,并提出拟合钢轨廓形贴合度评价指标和关键控制参数对廓形贴合度影响权重指标;以60 kg/m钢轨12号固定辙叉为例,采用DOE(design ... 详细信息

针对固定辙叉钢轨廓形不规则变化特点,基于B样条理论提出一种考虑固定辙叉钢轨断面廓形特征的参数化设计方法,并提出拟合钢轨廓形贴合度评价指标和关键控制参数对廓形贴合度影响权重指标;以60 kg/m钢轨12号固定辙叉为例,采用DOE(design of experiments)方法分析轨顶横坡、侧面纵坡和复合圆弧段比例系数对心轨轨头整体廓形、轨顶面廓形和侧面廓形的影响.结果表明:1)在心轨20 mm断面,轨顶横坡、侧面纵坡和复合圆弧段比例系数对心轨整体廓形变化的影响权重分别为21.08%、56.89%和22.02%,对心轨顶面廓形变化影响权重分别为8.42%、61.95%、29.63%;在心轨50 mm断面,各关键控制参数对心轨轨头整体廓形变化影响权重分别为55.9%、33.38%、10.72%;侧面纵坡对心轨20 mm和50 mm断面的侧面廓形变化影响权重分别为76.82%、66.04%.2)当心轨轨头宽度为20 mm时,侧面纵坡对各部分廓形变化影响均达到50%以上;随着心轨轨头宽度的增大,心轨轨顶横坡对整体廓形变化影响权重由21.8%增至55.9%,侧面纵坡和复合圆弧段比例系数影响权重则分别减小41.3%和51.3%.

关键词：道岔固定辙叉 B样条曲线钢轨廓形参数化设计 DOE设计

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Cdc42 deletion yielded enamel defects by disrupting mitochondria and producing reactive oxygen species in dental epithelium

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Genes & Diseases 2024年第5期11卷 335-349页

作者： jinxuan Zheng Rongcheng Yu Yiqi Tang Sihui Su Sainan Wang Chenxi Liao Xuecong Li jiabin Liao Dongsheng Yu Tingting Ai Wei Zhao Vicky Yau Chufeng Liu Liping Wu Yang cao Hospital of Stomatology Guanghua School of StomatologyGuangdong Provincial Key Laboratory of StomatologySun Yat-sen UniversityGuangzhouGuangdong 510055China Guangdong Provincial Key Laboratory of Oral Diseases GuangzhouGuangdong 510055China Department of Cariology and Endodontology Peking University School and Hospital of Stomatology&National Center for Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijing 100081China Department of Oral and Maxillofacial Surgery University at BuffaloBuffaloNY 14214USA Department of Orthodontics Stomatological HospitalSouthern Medical UniversityGuangzhouGuangdong 510280China

Developmental defects of enamel are common due to genetic and environmental factors before and after ***42,a Rho family small GTPase,regulates prenatal tooth development in ***,its role in postnatal tooth development,especially enamel formation,remains ***,we investigated Cdc42 functions in mouse enamel development and tooth repair after ***42 showed highly dynamic temporospatial patterns in the developing incisors,with robust expression in ameloblast and odontoblast ***,epithelium-specific Cdc42 deletion resulted in enamel defects in *** differentiation was inhibited,and hypomineralization of enamel was observed upon epithelial Cdc42 *** analysis showed that abnormal mitochondrial components,phosphotransferase activity,and ion channel regulator activity occurred in the Cdc42 mutant dental *** oxygen species accumulation was detected in the mutant mice,suggesting that abnormal oxidative stress occurred after Cdc42 ***,Cdc42 mutant mice showed delayed tooth repair and generated less calcified *** dysfunction and abnormal oxygen consumption were evidenced by reduced Apool and Timm8a1 expression,increased Atp5j2 levels,and reactive oxygen species overproduction in the mutant repair ***-specific Cdc42 deletion attenuated ERK1/2 signaling in the labial cervical *** Sox2 expression in the mutant labial cervical loop after clipping might lead to delayed tooth *** findings suggested that mitochondrial dysfunction,up-regulated oxidative stress,and abnormal ion channel activity may be among multiple factors responsible for the observed enamel defects in Cdc42 mutant ***,Cdc42 exerts multidimensional and pivotal roles in enamel development and is particularly required for ameloblast differentiation and enamel matrix formation.

关键词： Cdc42 Enamel defects Mitochondrial dysfunction Rho GTPase Tooth repair

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Ultrafast modulable 2DEG Huygens metasurface

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Photonics Research 2024年第5期12卷 1004-1015页

作者： HONGXIN ZENG XUAN CONG SHIQI WANG SEN GONG LIN HUANG LAN WANG HUAjIE LIANG FENG LAN HAOYI cao ZHENG WANG WEIPENG WANG SHIXIONG LIANG ZHIHONG FENG ZIQIANG YANG YAXIN ZHANG TIE jUN CUI Terahertz Communication Laboratory School of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 611730China Zhangjiang Laboratory Shanghai 201210China Yangtze Delta Region Institute(Huzhou) University of Electronic Science and Technology of ChinaHuzhou 313098China National Key Laboratory of Solid-State Microwave Devices and Circuits Hebei Semiconductor Research InstituteShijiazhuang 050051China Institute of Electromagnetic Space and State Key Laboratory of Millimeter Waves Southeast UniversityNanjing 210096China

Huygens metasurfaces have demonstrated remarkable potential in perfect transmission and precise wavefront modulation through the synergistic integration of electric resonance and magnetic ***,prevailing active or reconfigurable Huygens metasurfaces,based on all-optical systems,encounter formidable challenges associated with the intricate control of bulk dielectric using laser equipment and the presence of residual thermal effects,leading to limitations in continuous modulation ***,we present an ultrafast electrically driven terahertz Huygens metasurface that comprises an artificial microstructure layer featuring a two-dimensional electron gas(2DEG)provided by an AlGaN/GaN heterojunction,as well as a passive microstructure *** precise manipulation of the carrier concentration within the 2DEG layer,we effectively govern the current distribution on the metasurfaces,inducing variations in electromagnetic resonance modes to modulate terahertz *** modulation mechanism achieves high efficiency and contrast for terahertz wave *** investigations demonstrate continuous modulation capabilities of up to 6 GHz,a modulation efficiency of 90%,a transmission of 91%,and a remarkable relative operating bandwidth of 55.5%.These significant advancements substantially enhance the performance of terahertz metasurface ***,our work not only enables efficient amplitude modulation but also introduces an approach for the development of high-speed and efficient intelligent transmissive metasurfaces.

关键词： heterojunction precise surface

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