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世界橡胶工业 1983年第4期 68-77页

作者： c.j.Derham j.M.Eidinger 刘玉田

前言 Derham等人探讨了用低剪切刚度的橡胶支座对土木工程结构进行地震防护的方法。他们通过计算机预测了6层楼剪切壁结构对最大地面加速度为0.3g（重力加速度g为9.8米/秒2）的地震的响应程度,并对建筑在普通固定地基

关键词：橡胶支座建筑物垂直刚度桥梁支座加速度运动学剪切变形水平位移剪切刚度实验结果地震

Biodegradation of Styrene-Butadiene-Styrene coploymer via Sugars Attached to the Polymer chain

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Advances in Materials Physics and chemistry 2013年第2期3卷 112-118页

作者： Rakesh Singh Rishi Gupta Mukund G. Adsul Ramesh c. Kuhad Digambar V. Gokhale Anjani j. Varma Department of Microbiology University of Delhi (South Campus) New Delhi India National collection of Industrial Microorganisms Biochemical Sciences Division National Chemical Laboratory Pune India Polymer Science & Engineering Division National Chemical Laboratory Pune India

A synthetic method was developed to chemically attach few molecules of simple sugars like glucose, mannose, galactose, maltose and xylose (0.09 - 0.37 wt%) and with quaternary nitrogen pendants (0.42 - 0.46 atomic%) along the polybutadiene section of polystyrene-block-polybutadiene-block-polystyrene (SBS) block copolymer. These functionalized SBS copolymers were evaluated for biodegradation using the fungal culture Aspergillus niger NcIM 1025 (ATcc 9642) and bacterial culture Pseudomonas sp. NcIM 2220, and for antimicrobial properties using bacteria E. coli DH5α and Bacillus subtilis and yeasts Pichia stipitis NcIM 3497 and P. stipitis NcIM 3499. It was conclusively demonstrated that these modified SBS block copolymers were significantly more biodegradable than the unmodified SBS;the observed weight loss after biodegradation was ~4 - 14-fold for bacterial and ~7 - 36-fold for fungal cultures with respect to the sugar content of modified SBS. Preliminary studies on antimicrobial properties of these biodegradable polymers showed a 4% - 24% decrease in growth of the microorganisms E. coli and Bacillus subtilis studied.

关键词： Biodegradation Antimicrobial SBS Sugar Quaternary Nitrogen

Lineage relationship of cD8^＋ T cell subsets is revealed by progressive changes in the epigenetic landscape

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cellular & Molecular Immunology 2016年第4期13卷 502-513页

作者： joseph G. crompton Manikandan Narayanan Suresh cuddapah Rahul Roychoudhuri Yun ji Wenjing Yang Shashank j. Patel Madhusudhanan Sukumar Douglas c. Palmer Weiqun Peng Ena Wang Francesco M. Marincola christopher A. Klebanoff Keji Zhao j.hn S. Tsang Luca Gatt-inoni Nicholas P. Restifo Surgery Branch National Cancer Institute National Institutes of Health Bethesda MD 20892 USA cambridge Institute for Medical Research University of Cam bridge Cambridge CB20XY UK Systems Genomics and Bioinformatics Unit Laboratory of Systems Biology National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD 20892 USA Department of Environmental Medicine New York University School of Medicine Tuxedo NY 10987 USA Experimental Transplantation and Immunology Branch National Cancer Institute National Institutes of Health Bethesda MD 20892 USA Department of Physics The George Washington University Washington DC 20052 USA Research Branch Sidra Medical and Research Centre Doha Qatar Infectious Disease and Immunogenetics Section Department of Transfusion Medicine Clinical Center National Institutes of Health Bethesda MD 20892 USA clinical Investigator Development Program NCI/NIH Bethesda MD 20892 USA Systems Biology center National Heart Lung and Blood Institute National Institutes of Health Bethesda MD 20892 USA. Lombardi comprehensive cancer center Georgetown University Washington. DC 20007. United States. Bethesda. MD 20892. USA.

To better elucidate epigenetic mechanisms that correlate with the dynamic gene expression program observed upon T-cell differentiation, we investigated the genomic landscape of histone modifications in naive and memory cD8＋ T cells. Using a chlP-Seq approach coupled with global gene expression profiling, we generated genome-wide histone H3 lysine 4 （H3K4me3） and H3 lysine 27 （H3K27me3） trimethylation maps in naive, T memory stem cells, central memory cells, and effector memory cells in order to gain insight into how histone architecture is remodeled during T cell differentiation. We show that H3K4me3 histone modifications are associated with activation of genes, while H3K27me3 is negatively correlated with gene expression at canonical loci and enhancers associated with T-cell metabolism, effector function, and memory. Our results also reveal histone modifications and gene expression signatures that distinguish the recently identified T memory stem cells from other cD8＋ T-cell subsets. Taken together, our results suggest that cD8＋ lymphocytes undergo chromatin remodeling in a progressive fashion. These findings have major implications for our understanding of peripheral T-cell ontogeny and the formation of immunological memory.

关键词： TRANScRIPTION FAcTOR STEM-cELLS MEMORY EFFEcTOR DIFFERENTIATION BET FATE LYMPHOcYTES MAINTENANcE GENERATION

Azimuthal anchoring of a nematic liquid crystal on a grooved interface with anisotropic polar anchoring

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chinese Physics B 2012年第6期21卷 378-384页

作者：周璇张志东叶文江宣丽 State Key Laboratory of Applied Optics Changchun Institute of OpticsFine Mechanics and PhysicsChinese Academy of Sciences Graduate School of the chinese Academy of Sciences Department of Physics Hebei University of Technology

Zhang Y j et al.[Zhang Y j,Zhang Z D,Zhu L Z and Xuan L 2011 Liquid cryst.38 355] investigated the effects of finite polar anchoring on the azimuthal anchoring energy at a grooved interface,in which polar anchoring was isotropic in the local tangent plane of the *** this paper,we investigate the effects of both isotropic and anisotropic polar anchoring on the surface anchoring energy in the frame of Fukuda et al.’s *** results show that anisotropic polar anchoring strengthens the azimuthal anchoring of grooved *** the one-elastic-constant approximation（K11 = K22 = K33 = K）,the surface-groove-induced azimuthal anchoring energy is entirely consistent with the result of Faetti,and it reduces to the original result of Berreman with an increase in polar ***,the contribution of the surface-like elastic term to the Rapini-Papoular anchoring energy is zero.

关键词： azimuthal anchoring energy surface grooves anchoring isotropy anchoring anisotropy

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漫画技法从入门到精通草图篇 5

The Impact of Depressive Symptoms on Neuropsychological Performance Tests in HIV-Infected Individuals: A Study of the Hawaii Aging with HIV cohort

丛书名：中青动漫

2013年

作者： c·c动漫社

本书主要内容包括：草图的绘制工具和表现方法；掌握素描技法是绘画的基础；人物头部的草图表现；人物整体的草图表现；人物动态的草图表现等。

ISBN: (纸本)9787515314679

本书主要内容包括：草图的绘制工具和表现方法；掌握素描技法是绘画的基础；人物头部的草图表现；人物整体的草图表现；人物动态的草图表现等。

关键词：漫画绘画技法

来源：畅想之星图书光盘版（南... 评论

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World journal of AIDS 2011年第4期1卷 139-145页

作者： Sheri M. Shimizu Dominic c. chow Victor Valcour Kamal Masaki Beau Nakamoto Kalpana j. Kallianpur cecilia Shikuma Hawaii center for AIDS John A. Burns School of Medicine University of Hawaii at Manoa Honolulu USA.

Background: The frequency of neurocognitive impairment (NcI) in human immunodeficiency virus (HIV) -infected individuals remains high despite the availability of potent antiretroviral therapy (ART). The concurrence of depression among HIV-infected patients with NcI is common, especially among older individuals. Depression has been implicated as a risk factor for impaired neuropsychological performance (NP). This study explored the relationship between depressive symptoms and NP testing in HIV-infected individuals. Methods: A cross-sectional analysis was performed within the Hawaii Aging with HIV cohort, a large prospective study of cognition of older (50 or more years old) compared to younger (20 to 39 years old) HIV-infected individuals. Results: Two hundred and eighty-five HIV infected participants (157 older and 128 younger) were administered a battery of NP tests to measure performance in major cognitive domains. Depressive symptoms were measured using the Beck Depression Inventory (BDI). The rates of depressive symptoms and neuropsychological impairment were similar in older and younger groups. Multivariate analyses revealed depressive symptoms were associated with NP test impairment in the younger group. In the older group, depressive symptoms were not associated with NP. conclusion: This study suggests that depressive symptoms are associated with NP test impairment in younger HIV-infected individuals, but not in older individuals.

关键词： Depression HIV Neurocognitive Function Aging

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超级漫画素描技法萌美少女篇升级版升级版

Promising Efficacy of the <i>cola acuminata</i>Plant: A Mini Review

2013年

作者： c·c动漫社

本书内容包括：萌美少女的基础知识；萌美少女可爱面部的绘制；萌美少女独具特色的表情绘制；萌美少女漂亮的发型绘制等。

ISBN: (纸本)9787515318042

本书内容包括：萌美少女的基础知识；萌美少女可爱面部的绘制；萌美少女独具特色的表情绘制；萌美少女漂亮的发型绘制等。

关键词：素描技法漫画

来源：畅想之星图书光盘版（南... 评论

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Advances in Biological chemistry 2014年第4期4卷 240-245页

作者： Henry I. c. Lowe charah T. Watson Simone Badal Patrice Peart Ngeh j. Toyang joseph Bryant Bio-Tech R & D Institute Kingston Jamaica Educational and Scientific corporation Florida USA Institute of Human Virology University of Maryland School of Medicine Baltimore USA

cola acuminata also known as the bissy nut extract was originally endemic to Africa but is now present in a number of tropical countries including jamaica. Despite its rich history of ethnomedicinal use and promising bioactivity, there still exists limited research on this plant. Exploring and compiling the ethnomedicinal usage, identified bioactivities and isolates of c. acuminata will prove useful in steering future directional research with the hope of reaping the plant’s full beneficial properties. The plant’s traditional use encompass;cancer treatment, an antidote for poisoning, suppressing one’s appetite, increasing alertness, treating migraine and motion sickness, obtaining a state of euphoria in addition to being used in certain traditional practices. Because of the plant’s copious ethnomedicinal use, researchers were led to believe that the low incidence of prostate cancer evidenced amongst Asians could be as a result of phytochemicals present in the bissy nut. Research conducted in our lab confirmed the anti-cancer potential of the plant and recent research has identified a number of secondary metabolites present in c. acuminata which could be responsible for the observed bioactivities. The plant has also shown promise as an anti-microbial agent. This paper confirms the efficacy of the bissy nut plant both as an ethnomedicine as well as warranting further research that may prove useful both in the pharmaceutical and nutraceutical industries.

关键词： Bissy cola acuminata Prostate cancer Breast cancer cytotoxic

A generalized Weyl-Wigner quantization scheme unifying P-Q and Q-P ordering and Weyl ordering of operators

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chinese Physics B 2012年第6期21卷 207-212页

作者：王继锁范洪义孟祥国 Shandong Provincial Key Laboratory of Laser Polarization and Information Technology College of Physics and EngineeringQufu Normal University Department of Physics Liaocheng University Department of Physics Shanghai Jiao Tong University

By extending the usual Wigner operator to the s-parameterized one as 1/4π2 integral （dyduexp [iu（q-Q）＋iy（p-P）＋is/2yu]） from n=- ∞ to ∞ with s beng a,real parameter,we propose a generalized Weyl quantization scheme which accompanies a new generalized s-parameterized ordering *** rule recovers P-Q ordering,Q-P ordering,and Weyl ordering of operators in s = 1,1,0 *** it differs from the cahill-Glaubers’ ordering rule which unifies normal ordering,antinormal ordering,and Weyl *** also show that in this scheme the s-parameter plays the role of correlation between two quadratures Q and *** formula that can rearrange a given operator into its new s-parameterized ordering is presented.

关键词： generalized Wigner operator generalized operator ordering rule bivariate normal dis-tribution

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二甲酸钾提高南美白对虾的生长性能

饲料研究 2011年第10期34卷 78-79页

作者： K j Kühlmann O jintasataporn c Lückstdt 程宗佳张园程宗佳(摘译) 张园(摘译) 美国大豆协会国际项目北京办事处不详

2007年,在中美洲和东南亚地区,池塘密集养殖生产的南美白对虾产量超过200万t,只有在现代水产养殖中通过供应高质量的虾饲料才能获得这样高的产量。过去几年里,尽管在虾饲料的营养配方和新饲料配方策略方面有较大的进展。

关键词：南美白对虾生长性能二甲酸钾东南亚地区养殖生产水产养殖饲料配方营养配方

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