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FATIGUE LIVES FOR INDUCTION HARDENED SHAFTS MATERIALS ACCORDING TO THE ENVIRONMENTAL TEMPERATURES

Acta Metallurgica Sinica(English Letters) 2005年第5期18卷 585-593页

作者： D.G. Lee K.C. jang j.M. Kuk I.S. Kim Korea Institute of Industrial Technology Gwangju 506-824 Korea Dept. of Mechanical Engineering Mokpo National University Mokpo 534-729 Korea

Rotary bending fatigue tests were carried out with two kinds of materials, S43C and S50C, using the front engine and front drive shaft （ff shaft） of vehicle. The specimens were induction hardened about 1.0mm depth from the specimen surface, and the hardness value on the surface was about HRC56-60. The tested environment temperatures were -30, 25 and 80℃ in order to look over effect of the induction hardening and the environmental temperatures on the fatigue characteristics. The fatigue limit of induction hardened specimens increased more about 45% than non-hardened specimens showing that the endurances of S43C and S50C were 98.1 and 107.9MPa in non-hardened samples, 147.1 and 156.9MPa in hardened samplesrespectably. The maximum tensile and compressive stress on the small circular defect was about ＋250 and -450MPa respectively when circular defect is situated on top and bottom. The fatigue life increased 80, 25 and -30℃ in order regardless of hardening. In comparison of the fatigue lives on the basis of tested result at 25℃, the fatigue lives of non-hardened specimens decreased about 35%, but that of hardened specimens decreased about only 5% at 80℃ more than at 25℃. And fatigue life of non-hardened and hardened specimens were about 110% and 120% higher at -30℃ than that of 25℃. Based on the result of stress distribution near the defect, the tensile and compressive stress repeatedly generated by load direction were the largest on the small circular defect due to the stress concentration.

关键词： induction hardening fatigue test front engine and front drive shaft,fatigue crack fatigue life fatigue life ratio

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Extracts of the seaweed Bifurcaria bifurcata display antifungal activity against human dermatophyte fungi

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journal of Oceanology and Limnology 2019年第3期37卷 848-854页

作者： CARVALHO G.Loic SILVA Raquel GONCALVES j.Maria BATISTA T.Maria PEREIRA Leonel Environmental and Biochemical Sciences Group the James Hutton InstituteDundee DD2 5DAScotlandUK Institute of Mechanical Process and Energy EngineeringSchool of Engineering and Physical SciencesHeriot Watt UniversityEdinburgh EH14 4ASScotlandUK MARE (Marine and Environmental Sciences Centre) Department of Life SciencesFaculty of Sciences and TechnologyUniversity of CoimbraCoimbra 3030-790Portugal CIEPQPF Department of Chemical EngineeringFaculty of Science and TechnologyUniversity of CoimbraCoimbra 3030-790Portugal

Bifurcaria bifurcata is a seaweed of the Order Fucales(Ochrophyta,Phaeophyceae)that can be found all year round along the Portuguese Atlantic *** it is considered edible in some countries,its biotechnological potential has not yet been assessed in detail and here we report its antimicrobial potential against human dermatophyte *** samples were harvested from Baleal Island(Peniche,Portugal)harvested in winter(BbPe);from Aguda Beach(Arcozelo,Vila Nova de Gaia,Portugal),harvested in autumn(BbAg)and a sample obtained by culturing the Aguda sample under laboratory conditions(BbLC).A broth macrodilution assay was applied to determine the MIC(minimum inhibitory concentration)and MLC(minimum lethal concentration)of the *** *** show that the BbPe MeOH extracts were the most effective and had higher antifungal activity against all the tested dermatophyte strains than the BbLC and BaAg extracts[Epidermophyton floccosum ff9(100–200μg/mL MIC;200μg/mL MLC),Microsporum canis ff1(400μg/mL MIC;≥400μg/mL MLC),Trichophyton mentagrophytes ff7(100μg/mL MIC;>800μg/mL MLC),*** CECT 2908(800μg/mL MIC;≥800μg/mL MLC),*** *** CECT 2958(800μg/mL MIC;≥800μg/mL MLC),*** CECT 2794(200μg/mL MIC;≥400μg/mL MLC)].In fact,only *** ff9 was sensitive to BbAg and BbLC MeOH *** our knowledge,this is the first report of antifungal activity of *** against human dermatophyte fungi.

关键词： seaweed Bifurcaria bifurcata bioactivity antifungal dermatophytes minimum inhibitory concentration minimum lethal concentration

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无机活性元素骨组织工程支架材料修复山羊颌骨缺损

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中国组织工程研究与临床康复 2007年第48期11卷 9627-9632页

作者：叶茂昌 Chou L 王来平李容新陈梅梅康然刚周媛白冰龚飞飞黄婕周瑜安徽医科大学附属省立医院安徽省立医院口腔医学中心颌面外科研究室安徽省合肥市230001 波士顿大学医学中心

目的:应用无机活性元素骨组织工程支架材料,对山羊的下颌骨角部大型箱状缺损施行骨重建,观察支架材料骨构建效能和生物相容性的情况。方法:实验于2004-02/12在安徽医科大学附属省立医院实验中心及相关实验室完成。①实验材料:无机活性... 详细信息

目的:应用无机活性元素骨组织工程支架材料,对山羊的下颌骨角部大型箱状缺损施行骨重建,观察支架材料骨构建效能和生物相容性的情况。方法:实验于2004-02/12在安徽医科大学附属省立医院实验中心及相关实验室完成。①实验材料:无机活性元素骨组织工程支架材料由美国波士顿大学分子生物相容学研究室研制提供;21只雌性健康山羊由安徽医科大学动物实验中心(皖医实动准字01号)提供,实验过程中动物处置符合动物伦理学标准。②实验方法:取山羊15只,按4,8,12周3个时间点分为3组,位下颌角部手术制备30 mm×25 mm×10 mm的大型箱状缺损。采用自身配对设计,左侧置入支架材料为实验组,右侧空白对照为对照侧;剩余6只山羊为对照组,不手术。③观察指标:术后4,8,12周应用X射线片、组织学和放射性核素显像观察缺损区新骨形成情况;并测定骨密度;应用血液学检查及骨髓基质细胞体外复合细胞培养评价材料的生物相容性。结果:①一般观察:实验山羊无手术死亡,创口Ⅰ期愈合。②X射线片:实验侧有渐进性骨密度增高,阻射影逐级增强,对照侧呈透光阴影。③放射性核素显像:实验侧有较明显的核浓聚和再生血管化现象,对照侧无骨重建,故无骨代谢变化。④骨密度测量系数:实验侧呈递增式上升,对照侧维持较低水平,提示无自发性成骨。⑤组织学观察:实验侧呈时间递增性骨重建现象,在12周时新骨已完全形成并钙化基本完成,而对照侧直到12周仍无成骨现象。⑥生物相容性:各组的血常规、细胞形态、生化和相关酶学指标均在正常范围内。结论:无机活性元素骨组织工程支架材料有良好的成骨和再血管化功能,且生物相容性好,提示由该支架材料诱导的组织工程化骨构建有望成为临床骨组织大型缺损的替代材料。

关键词：无机活性元素支架材料山羊颌骨缺损

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Subcutaneous tunnel and hepatocholangio-plasty after resection for intrahepatic stones

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Hepatobiliary & Pancreatic Diseases International 2006年第3期5卷 474-475页

作者： j.E.j.Krige S.j.Beningfield MD FACS FRCSPCS(SA) Department of SurgeryUniversity of Cape Town Health Sciences FacultyAnzio RoadObservatoryCape Town 7925South Africa ff Rad(D)(SA)Department of Radiology University of Cape Town Health Sciences Faculty Anzio RoadObservatoryCape Town 7925South Africa

The Editor welcomes submissions for possible publication in the Letters to the Editor section that consist of commentary on an article published in the journal or other relevant issues. Letters commenting on an article published in the journal will be considered if they are received within 6 weeks of the time the article was published. Authors of the article being commented on will be given an opportunity to offer a timely response to the letter. Authors of letters will be notified that the letter has been received. Unpublished letters cannot be returned.

关键词： Subcutaneous tunnel and hepatocholangio-plasty after resection for intrahepatic stones

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中国人的ABCB1功能性基因多态性与慢性肾脏病和高血压相关

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中华高血压杂志 2014年第2期22卷 198-198页

作者： Liu M Li Y Citterio L Huang QF Zeng wF Sheng CS wei ff Dong Q Li GL Kang YY Zhang L Xu TY Li jj Song j Manunta P wang jG 罗冬梅

渗透性糖蛋白是ATP结合盒B亚家族成员1转运蛋白基因（ATP—bindingcassettesubfamilyBmem—ber1transportergene，ABCBl）编码的产物，其功能为排解肾脏毒性代谢物。人ABCBl基因的常见功能多态性（C3435T，rsl045642）与肾移植患者的术... 详细信息

渗透性糖蛋白是ATP结合盒B亚家族成员1转运蛋白基因（ATP—bindingcassettesubfamilyBmem—ber1transportergene，ABCBl）编码的产物，其功能为排解肾脏毒性代谢物。人ABCBl基因的常见功能多态性（C3435T，rsl045642）与肾移植患者的术后预后相关。该研究调查在2个中国人群中，C3435T多态性与肾功能及血压的相关性。方法：选取山区人群（浙江省）和新近城市化郊区人群（上海）分别进行初步发现和进一步验证研究。采用多重SNaPshotSNP分型方法进行基因分型。

关键词：基因多态性中国人群高血压慢性肾脏病功能性 C3435T 功能多态性肾移植患者

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Physical separation from the mate diminishes male＇s attentiveness towards other females： a study in monogamous prairie voles Microtus ochrogaster

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Current Zoology 2017年第5期63卷 537-544页

作者： Christine j. DELEVAN Natalia A. RODRIGUEZ Karine M. LEGZIM Fayeza ALIOU jamie T. PARKER Maryam BAMSHAD Department of Biological Sciences Lehman College--The City University of New York Bronx NY 10468 USA

we tested whether continuous cohabitation in monogamous voles affects the mated male＇s atten-tiveness to his breeding partner versus another female. Each male was housed in a 3-chamber ap-paratus with a Focal female （ff） and a Control female （CF） for 13 days then placed in a T-maze toassess his attentiveness to and memory of those females. The Distal male remained physically sep-arated from both females, but received their distal cues. The Separate male cohabited with the fffor 3 days then remained physically separated from both females. The Disrupt male＇s continuouscohabitation with the ff was disrupted by having him physically separated from her after 10 daysand placed with the CF for the last 3 days. The Continuous male cohabited continuously with the fffor 13 days. with females in the T-maze, the Separate and Disrupt males spent more time near theff＇s box and the Disrupt males spent more time manipulating the ff＇s box than the CF＇s box. TheSeparate males groomed themselves more when near the ff＇s box than the CF＇s box. The Distaland Continuous males＇ attentiveness to the two females did not differ. Results suggest that phys-ical distance from the partner may reduce male＇s attentiveness toward other potential *** voles might be similar to socially monogamous primates in using tactile cues as a signal formaintaining their social bonds.

关键词： attachment, monogamy, partner preference, partner separation, social cognition.

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Effects of Low Chloride versus High Chloride Infusion on Glomerular Filtration Rate and Renal Plasma Flow in Healthy Volunteers—A Randomized, Controlled, Crossover Study

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Open journal of Nephrology 2020年第2期10卷 73-84页

作者： A. E. Oczachowska-Kulik j. A. Ejlersen j. j. jensen M. H. Malmberg j. N. Bech University Clinic in Nephrology and Hypertension The Regional Hospital West Jutland Holstebro and Aarhus University Aarhus Denmark Department of Nuclear Medicine The Regional Hospital West Jutland Herning Denmark

Background: Previous studies have shown that chloride liberal fluids may be associated with worse renal outcomes. Deterioration of kidney function during hyperchloremia/chloride overload is believed to be induced by disturbances in renal perfusion, but exact mechanisms of chloride nephrotoxicity are unclear. The purpose of this randomized, crossover study was to investigate the effect of chloride loading on renal plasma flow (RPF), filtration fraction (ff) and glomerular filtration rate (GFR) in order to elucidate potential nephrotoxic mechanisms of chloride infusion. Methods: Fifteen healthy males were investigated twice after treatment with 2L isotonic saline and plasma-lyte with a wash-out period of at least 10 days. within 15 mins after completion of infusion, the kidney parameters (RPF, ff and GFR) were estimated by Technetium-99m diethylenetriamine penta-acetic acid (99-mTc-DTPA) renography. Results: 99-mTc-DTPA renography showed reduction in both mean GFR (114 ± 13 ml/min vs.119 ± 12 ml/min, p = 0.04) and RPF (977 ± 272 ml/min vs. 1066 ± 197 ml/min, p = 0.19) and increasing ff (12% ± 2% vs. 11% ± 2%, p = 0.19) after 0.9% saline comparing to Plasmalyte, but only GFR reduction was statistically significant. Reduction in GFR and RPF and increasing in ff after 0.9% saline was observed in 10 subjects while in 5 others the reverse trend was shown. There were no statistically significant differences between mean systolic and diastolic blood pressure (BP) before and after each infusion except baseline diastolic BP. weight changes (Δ weight) were similar after each infusion. Conclusions: we have demonstrated that high chloride infusion can affect kidney function in healthy subjects and seems to lead to impairment in both RPF and GFR.

关键词： Chloride Nephrotoxicity Renal Plasma Flow Glomerular Filtration Rate Renography

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游泳训练阻止高血压大鼠乙酰胆碱酯酶和丁酰胆碱酯酶活力的变化

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中华高血压杂志 2014年第6期22卷 598-598页

作者： Cardoso AM Abdalla FH Bagatini MD Martins CC Fiorin Fda S Baldissarelli j Costa P Mello ff Fiorenza AM Serres jD Gonalves jF Chaves H Royes LF Belló-Klein A Morsch VM Schetinger MR 罗冬梅叶鹏

胆碱酶活性在高血压患者中呈现异常,反映了低度炎症。经常进行体育运动产生的抗炎作用可作为高血压治疗的辅助措施。该研究调查左旋硝基精氨酸甲酯（Nω-nitro-L-arginine-methyl-ester,l-NAME）诱导的高血压大鼠进行6周游泳训练对胆碱... 详细信息

胆碱酶活性在高血压患者中呈现异常,反映了低度炎症。经常进行体育运动产生的抗炎作用可作为高血压治疗的辅助措施。该研究调查左旋硝基精氨酸甲酯（Nω-nitro-L-arginine-methyl-ester,l-NAME）诱导的高血压大鼠进行6周游泳训练对胆碱酶活性（乙酰胆碱酯酶和丁酰胆碱酯酶）的影响。方法：大鼠随机分为4组：对照组（n=10）,运动组（n=10）,l-NAME组（n=10）和运动＋l-NAME组（n=10）。对大鼠进行游泳训练,60min/次,每周5次,并根据大鼠体质量逐级增加负荷至上限为体质量的5%。用分光光度计测定淋巴细胞、全血和血清的酶活性。

关键词：高血压大鼠乙酰胆碱酯酶游泳训练胆碱酯酶活力左旋硝基精氨酸甲酯胆碱酶活性丁酰胆碱酯酶 l-NAME

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原生质体融合获得柑桔种间体细胞杂种

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Acta Genetica Sinica 1992年第2期19卷 140-144页

作者：邓秀新 Grosser.j.w Gmitter.F.G. 华中农业大学园艺系柑桔研究室武汉430070 美国佛罗里达大学柑桔研究及教育中心 fl33850

粗柠檬(Citrus jambhiri Lush)叶肉原生质体与哈姆林甜橙(*** ***)胚性悬浮细胞系原生质体经PEG诱导融合,培养7天时原生质体恢复分裂。再生的胚状体在含有GA_3的培养基中萌发出茎芽。茎芽经生根诱导成为完整植株。对首批再生的5棵植株... 详细信息

粗柠檬(Citrus jambhiri Lush)叶肉原生质体与哈姆林甜橙(*** ***)胚性悬浮细胞系原生质体经PEG诱导融合,培养7天时原生质体恢复分裂。再生的胚状体在含有GA_3的培养基中萌发出茎芽。茎芽经生根诱导成为完整植株。对首批再生的5棵植株进行染色体检查,结果表明,全为四倍体,2n=4x=36。淀粉胶电泳分析过氧化物酶同工酶,结果显示这5棵植株为体细咆杂种。粗柠檬和哈姆林甜橙在该位点上均为同质结合,基因型分别是MM和ff。体细胞杂种含有双亲的酶带,基因型为MMff。杂种植株生长旺盛,根系发达,叶片及植株形态介于双亲之间。本文对其作为砧木品种的可能性等问题作了讨论。

关键词：柑桔原生质体融合体细胞杂种

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Completeness,Passivity and Stability of Switched Systems

Completeness,Passivity and Stability of Switched Systems

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第二十七届中国控制会议

作者： Hill David j. Department of Information Engineering Research School of Information Sciences and EngineeringThe Australian National University

This paper focuses on passivity of subsystems of a switched system on their active *** individual passivity property is characterized by *** allow each subsystem to have individual storage function to describe the passivity *** conditions under which individual passivity property produces stability are given in terms of specific *** feedback controllers and switching laws are also *** some detactability of subsystems,asymptotic stability is derived.

关键词： Completeness Passivity Stability Switched systems

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