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Comparison of skeletal and soft tissue pericytes identifies CXCR4+ bone forming mural cells in human tissues

Bone Research 2020年第3期8卷 286-299页

作者： jiajia Xu Dongqing Li Ching-Yun Hsu Ye Tian Leititia Zhang Yiyun Wang Robert j.Tower Leslie Chang Carolyn A.Meyers Yongxing Gao Kristen Broderick Carol Morris j.dy e.hooper Sridhar Nimmagadda Bruno Peault Aaron W.james Departments of Pathology Johns Hopkins UniversityBaltimore 21205 MDUSA Department of Microbiology Wuhan University School of Basic Medical of ScienceWuhanHubeiP.R.China Department of Oral and Maxillofacial Surgery School of StomatologyChina Medical UniversityShenyangLiaoningP.R.China Departments of Orthopaedics Johns Hopkins UniversityBaltimore 21205 MDUSA Departments of Plastic Surgery Johns Hopkins UniversityBaltimore 21205 MDUSA Departments of Autopsy Service Johns Hopkins UniversityBaltimoreMD 21205USA Departments of Radiology and Radiological Science bonBaltimore 21205 MDUSA UCLA and Orthopaedic Hospital Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center Los AngelesCA 90095USA Center for Cardiovascular Science and MRC Center for Regenerative Medicine University of EdinburghEdinburghUK

Human osteogenic progenitors are not precisely defined,being primarily studied as heterogeneous multipotent cell populations and termed mesenchymal stem cells(MSCs).Notably,select human pericytes can develop into bone-forming ***,we sought to define the differentiation potential of CD146 f human pericytes from skeletal and soft tissue sources,with the underlying goal of defining cell surface markers that typify an osteoblastogenic ***146+CD31~CD45_pericytes were derived by fluorescence-activated cell sorting from human periosteum,adipose,or dermal *** CD146+CD31—CD45 cells retained canonical features of pericytes/*** pericytes demonstrated a striking tendency to undergo osteoblastogenesis in vitro and skeletogenesis in vivo,while soft tissue pericytes did not *** analysis revealed higher CXCR4 signaling among periosteal pericytes in comparison to their soft tissue counterparts,and CXCR4 chemical inhibition abrogated ectopic ossification by periosteal ***,enrichment of CXCR4+pericytes or stromal cells identified an osteoblastic/non-adipocytic precursor *** sum,human skeletal and soft tissue pericytes differ in their basal abilities to form *** exists in soft tissue pericytes,however,and CXCR4+pericytes represent an osteoblastogenic,non-adipocytic cell ***,enrichment for CXCR4-expressing stromal cells is a potential new tactic for skeletal tissue engineering.

关键词： CD146 CXCR4 pericyte

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Five New Glycosides, Ligurobustosides e, F, I, j and K from Ligustrum Robustum

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Chinese Chemical Letters 1997年第2期8卷 125-128页

作者： Tian, j Zhang, Hj Sun, HD Pan, LT Yao, P Chen, dy KUNMING INST BOT LAB PHYTOCHEMKUNMING 650204PEOPLES R CHINA GUIZHO INST TRADIT CHINeSe MeD GUIYANG 550002PEOPLES R CHINA

Five new monoterpenoid glycosides named ligurobustosides e (1), F (2), I (3), j (4) and K (5) were isolated from the leaves of Ligustrum robustum. Their structures were established by spectroscopic and chemical methods.

关键词： jASONIA-MONTANA

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CONSIDeRATIONS WHeN SPeCIFYING LITHIUM ADMIXTUReS TO MITIGATe THe RISK OF ASR

CONSIDERATIONS WHEN SPECIFYING LITHIUM ADMIXTURES TO MITIGAT...

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第十二届国际混凝土碱集料反应会议

作者： Rebecca L hooper Philip j Nixon Michael D A Thomas Scott Wilson Pavement engineering 9/10 Faraday BuildingNottingham Science and Technology ParkUniversity BoulevardNottinghamNG7 2QPUK. Building Research establishment Garston WatfordWD25 9XXUK. Department of Civil engineering Head HallUniversity of New BrunswickFrederictonNBE3B 5A3Canada.

＜正＞ Based on research conducted at the Building Research establishment （BRe） and work from across the globe, theUK has established recommended addition levels of lithium admixtures as one method to minimize the risk ofdeleterious alkali-silica reaction （ASR）.These addition levels allow increases in the permitted alkali content of concrete mixtures beyond that previouslyrecommended in the UK, and allow for combinations of lithium admixtures with pulverized-fuel ash （pfa） alsoknown as fly ash, a supplementary cementitious material or Type Ⅱ*** the impossibility of testing every lithium admixture addition level in combination with every alkali contentconcrete mixture, the recommendations are based on a pragmatic approach to safe specification. Thisspecification process includes interpolation of threshold levels and determination of an appropriate margin ofsafety based on concrete batching practices in the UK and embodied in european *** paper provides an overview of the use of lithium salts to mitigate deleterious ASR and provides furtherresearch evidence to validate the findings of previous authors. The paper explains the research basis for the UKrecommendations and describes the approach to the safe specification of lithium admixtures. Theserecommendations were published in BRe Information paper IP 1/02, and are now included in the 2004 edition ofBRe Digest 330, and referenced in the British Standard, BS 8500.

关键词： Lithium Specification Pulverized-fuel ash Fly ash.

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Critical parameters near the phase transition temperature in La_(0.67–x)dy_xPb_(0.33)MnO_3

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journal of Rare earths 2015年第2期33卷 168-176页

作者： N.Zaidi S.Mnefgui A.Dhahri e.K.Hlil j.Dhahri Laboratory of Condensed Matter and Nanosciences University of Monastir5019 Tunisia Institut Néel CNRS and Joseph Fourier universityB.P.16638042 Grenoble France

La0.67–xdyxPb0.33MnO3（x=0.00 and x=0.10） were elaborated by the solid state method and checked by X-ray diffraction. Close to magnetic temperature transition, the order transition and the critical behavior were investigated by dc magnetization measurements versus x composition. The critical properties were investigated through various techniques such as modified Arrott plot（MAP）, Kouvel-Fisher（KF） method and critical isotherm（CI） analysis based on the data of static magnetic measurements recorded around the Curie temperature TC. The values of critical exponents（β and γ） estimated were found to lie between those predicted for a 3D-Ising model for x=0.00 and those of 3D-Heisenberg model for x=0.10. The reliability of the critical exponent＇s values was confirmed by the Widom scaling relation and the universal scaling hypothesis. The change in the universality class should be due to the increase of the dy content.

关键词： Arrott plots critical exponent site A-substitution rare earths

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大肠埃希菌临床分离株对喹诺酮类抗菌药的质粒介导耐药

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中国感染与化疗杂志 2006年第4期6卷 217-221页

作者：王明贵 johnH.Tran GeorgeA.jacoby 张婴元汪复 DavidC.hooper 复旦大学附属华山医院抗生素研究所上海200040 美国哈佛医学院麻省总医院感染科美国Lahey医学中心感染科

目的了解近年来发现的质粒介导耐药机制在大肠埃希菌临床株对喹诺酮类耐药中所起的作用。方法78株环丙沙星耐药菌株分离自上海5所教学医院。以克隆斑点杂交及Southern杂交方法筛选质粒介导耐药基因qnr；以接合试验了解喹诺酮耐药的可转... 详细信息

目的了解近年来发现的质粒介导耐药机制在大肠埃希菌临床株对喹诺酮类耐药中所起的作用。方法78株环丙沙星耐药菌株分离自上海5所教学医院。以克隆斑点杂交及Southern杂交方法筛选质粒介导耐药基因qnr；以接合试验了解喹诺酮耐药的可转移性；对qnr基因进行序列分析,以引物步移法对qnr周边质粒DNA进行测序、分析。结果78株大肠埃希菌中,6株(7．7%)qnr检测阳性。在6株阳性菌中,喹诺酮耐药性均可通过质粒转移,接合子对环丙沙星的MIC较受体菌上升16～250倍。qnr基因与最早报道的序列一致,qnr位于In4族的Ⅰ类整合子上,本研究中的2个新整合子命名为In36及In37。结论与qnr相关的质粒介导喹诺酮类耐药性在大肠埃希菌临床分离株中有一定程度流行,这可能是我国细菌对喹诺酮类耐药性上升迅速的原因之一。

关键词：大肠埃希菌质粒介导耐药喹诺酮类 qnr

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Geochemical studies of hybrid granite from Madugulapalli area, eastern Dharwar Craton, Southern India: Implications for crustal mixing

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Acta Geochimica 2023年第1期42卷 9-23页

作者： Nagamma j Ratnakar j Ajay kumar A Ashok Ch State Mines and Geology Department 508001 NalgondaIndia Department of Geology Osmania University500007 HyderabadIndia CSIR-National Geophysical Research Institute 500007 UppalHyderabadIndia

Magma produced by melting of continental crust and mantle at the Archean-Proterozoic boundary are compositionally variable and chemical compositions provide evidence for the mixing of two sources. Understanding the composition of hybrid magma is essential for determining the comparative infl uence of crust and mantle sources during orogenesis. The hybrid granites are less documented in Indian cratons, especially less in Dharwar Craton. Here we present petrographic and whole-rock geochemical data of Madgulapalli granitic rocks situated in the Ne part of the eastern Dharwar Craton(eDC), to elucidate their petrogenesis and role in crust formation. The Madugulapalli granites(MPG) are composed chiefl y of plagioclase, quartz, and alkali feldspar with associated biotite showing alteration and inter-granular textures. Geochemically, they are metaluminous to peraluminous in nature with calc-alkaline hybrid granite. The hybrid granites exhibit both negative and positive europium anomalies;the lower Rb/Sr, Rb, Sr, and higher Sr/Y,(dy/Yb)N ratios suggest that the interaction of older rocks with residual garnet source melted at high pressures. We hypothesize that hybrid granites are formed by interaction(e.g., metasomatism, mingling, or mixing) between parental magmas and pre-existing rocks with the infl uence of sanukitoid melts(heat source) in a subduction environment. The genesis of the hybrid granites demonstrates the mixing coupled with diff erentiation in the petrogeny’s residue system in a syn-collision setting followed by continental crust stability in eDC during the Neoarchean period.

关键词： Madugulapalli granite Hybrid granite Crustal mixing Subduction

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形变核中的e2和M1强度 :赝-SU(3)模型的应用(英文)

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高能物理与核物理 2004年第12期28卷 1297-1301页

作者： j.P.Draayer G.Popa j.G.Hirsch C.e.Vargas 路易斯安那州立大学物理与天文系美国巴顿鲁日LA70808-4001 罗切斯特技术学院物理系美国罗切斯特NY14623-5612 墨西哥独立大学核物理研究所墨西哥墨西哥城04510DF 威拉科鲁扎那大学物理与人工智能系墨西哥夏拉帕威拉科鲁扎那91000

通过赝 SU(3)壳模型对16 2 dy核的描述 ,揭示了原子核的复杂多体行为能通过简单的几何图像来解释 .

关键词： SU 行为复杂描述图像解释壳模型原子核形变

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early Water Quality Modeling with Minimal Data to Support Management Decisions： A Case Study of Aguamilpa Reservoir

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journal of environmental Science and engineering 2011年第6期5卷 667-681页

作者： O. Obregon G.P. Williams e.j. Nelsont j. de Anda j.B. Miller D. erickson F.A. Gonzalez-Farias j.G.Rangel-Peraza Department of Civil and environmental engineering Brigham Young University Provo Utah 84602 USA Center of Investigation and Technology and Design of jalisco A.C. Guadalajara City Jalisco 44270 Mexico Water Quality LLC. Hooper Utah 84315 USA Institute of Marine Sciences and Limnology National Autonomous University of Mexico Mexico City D.F. 0451 O Mexico

This paper presents a case study that demonstrates how models can be used to support water management decisions before sufficient data to verify the model are available. In developing areas, and for new reservoirs, extensive data for model calibration and validation are often not available. As a case study we developed a Ce-QUAL-W2 model of Aguamilpa Reservoir using minimal data and used the model to create a data acquisition plan to support early planning decisions. We based the model on a two-year period and compared the model results to data recently collected with our acquisition plan. We present how we developed and used the model to design the data acquisition plan which identifies and collects data to update and calibrate the model to support future decisions. We show that a minimally calibrated model based on scarce data can support management decisions and be the first step in a spiral engineering approach to system management. Spiral engineering uses models and data to both support early decisions and to iteratively improve this information to support subsequent decisions and models. This case study can be used as a guide for developing water quality models with minimal data and uses the models to support early decision requirements.

关键词： Preliminary modeling water quality tropical Ce-QUAL-W2 minimal data.

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Rare-earth-niobate high-entropy ceramic foams with enhanced thermal insulation performance

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journal of Materials Science & Technology 2022年第21期116卷 94-102页

作者： R.W.Yang Y.P.Liang j.Xu X.Y.Meng j.T.Zhu S.Y.Cao M.Y.Wei R.X.Zhang j.L.Yang F.Gao State Key Laboratory of Solidification Processing MIIT Key Laboratory of Radiation Detection Materials and DevicesSchool of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi’an710072China NPU-QMUL joint Research Institute of Advanced Materials and Structure Northwestern Polytechnical UniversityXi’an710072China State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing100084China State Key Laboratory of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan430074China

The introduction of porous structures into high-entropy ceramics is expected to further improve its thermal insulation *** this work,a series of novel rare-earth-niobate high-entropy ceramic foams((dy_(0.2)Ho_(0.2)Y_(0.2)er_(0.2)Yb_(0.2))_(3)NbO_(7))with hierarchical pore structures were prepared by a particle-stabilized foaming ***-scale analysis reveals that high entropy causes atom displacement and lattice *** high-entropy ceramic foams exhibit high porosity(90.13%-96.13%)and ultralow thermal conductivity(0.0343-0.0592 W/(m·K))at room ***-entropy ceramic foam prepared by a 20 wt%slurry sintered at 1500℃has the porosity of 96.12%and extremely low thermal conductivity of 0.0343 W/(m·K).The existence of walls and secondary pores contributes to reduced thermal *** is a temperature difference of over 800℃between frontside and backside of the sample under fire resistance *** research indicates that these as-prepared high-entropy ceramic foams are expected to be promising thermal insulation materials.

关键词： Rare-earth niobate High-entropy ceramic foams Particle-stabilized foaming Atomic-scale analysis Thermal conductivity

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Recent Progress of Research on Multi-phonon γ-Bands in A～100 Neutron-Rich Nuclei

Recent Progress of Research on Multi-phonon γ-Bands in A～1...

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第十三届全国核结构研讨会暨第九次全国“核结构与量子力学”专题讨论会

作者： j.H.Hamilton A.V.Ramayya j.K.Hwang j.O.Rasmussen I.Y.Lee e.Y.Yeoh Department of Physics Vanderbilt UniversityNashvilleTennessee 37235USA Department of Physics Mississippi State UniversityMississippi StateMississippi 39762USA Department of Physics Tsinghua UniversityBeijing 100084People’s Republic of China

Multi-phonon excitation in deformed nuclei is an impotent topic in research on nuclear structure. Up to now,the one-phononγ-vibrational（1-γ） bands have been observed in many ***,it is difficult to observe the two-phononγ-vibrational（2-γ） *** to now,only few 2-γbands were observed in A～170 and 220 regions,for examples,in er,dy and *** the A～100 neutron rich nuclei,2-γbands were reported in Mo in earlier *** our work,no 2-γband was identified in odd-A *** identify 2-γband in odd-A nuclei is important to understand nuclear single-particle motion and collective motion and to develop the nuclear model *** we report on recent progress of research on two-phononγ-bands in A00 neutron-rich nuclei by our cooperative group.

关键词： spontaneous fission neutron-rich nuclei multi-phononγ-bands

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