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Search for electron-antineutrinos associated with gravitational-wave events GW150914,GW151012,GW151226,GW170104,GW170608,GW170814,and GW170817 at Daya Bay

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Chinese Physics C 2021年第5期45卷 190-201页

作者： F.P.An A.B.Balantekin H.R.Band M.Bishai S.Blyth G.F.Cao j.Cao j.F.Chang Y.Chang H.S.Chen S.M.Chen Y.Chen Y.X.Chen j.Cheng Z.K.Cheng j.j.Cherwinka M.C.Chu j.P.Cummings O.Dalager F.S.Deng Y.Y.Ding M.V.Diwan T.Dohnal j.dove M.Dvorak D.A.Dwyer j.P.Gallo M.Gonchar G.H.Gong H.Gong W.Q.Gu j.Y.Guo L.Guo X.H.Guo Y.H.Guo Z.Guo R.W.Hackenburg S.Hans M.He K.M.Heeger Y.K.Heng A.Higuera Y.K.Hor Y.B.Hsiung B.Z.Hu j.R.Hu T.Hu Z.j.Hu H.X.Huang X.T.Huang Y.B.Huang P.Huber D.E.jaffe K.L.jen X.L.ji X.P.ji R.A.johnson D.jones L.Kang S.H.Kettell S.Kohn M.Kramer T.j.Langford j.Lee j.H.C.Lee R.T.Lei R.Leitner j.K.C.Leung F.Li j.j.Li Q.j.Li S.Li S.C.Li W.D.Li X.N.Li X.Q.Li Y.F.Li Z.B.Li H.Liang C.j.Lin G.L.Lin S.Lin j.j.Ling j.M.Link L.Littenberg B.R.Littlejohn j.C.Liu j.L.Liu C.Lu H.Q.Lu j.S.Lu K.B.Luk X.B.Ma X.Y.Ma Y.Q.Ma C.Marshall D.A.Martinez Caicedo K.T.MeDonald R.D.McKeown Y.Meng j.Napolitano D.Naumov E.Naumova j.P.Ochoa-Ricoux A.OIshevskiy H.-R.Pan j.Park S.Patton j.C.Peng C.S.j.Pun F.Z.Qi M.Qi X.Qian N.Raper j.Ren C.Morales Reveco R.Rosero B.Roskovec X.C.Ruan H.Steiner j.L.Sun T.Tmej K.Treskov W.-H.Tse C.E.Tull B.Viren V.Vorobel C.H.Wang j.Wang M.Wang N.Y.Wang R.G.Wang W.Wang W.Wang X.Wang Y.Wang Y.F.Wang Z.Wang Z.Wang Z.M.Wang H.Y.Wei L.H.Wei L.j.Wen K.Whisnant C.G.White H.L.H.Wong E.Worcester D.R.Wu F.L.Wu Q.Wu W.j.Wu D.M.Xia Z.Q.Xie Z.Z.Xing j.L.Xu T.Xu T.Xue C.G.Yang L.Yang Y.Z.Yang H.F.Yao M.Ye M.Yeh B.L.Young H.Z.Yu Z.Y.Yu B.B.Yue S.Zeng Y.Zeng L.Zhan C.Zhang F.Y.Zhang H.H.Zhang j.W.Zhang Q.M.Zhang X.T.Zhang Y.M.Zhang Y.X.Zhang Y.Y.Zhang Z.j.Zhang Z.P.Zhang Z.Y.Zhang j.Zhao L.Zhou H.L.Zhuang j.H.Zou Instiute of Modern Physics East China University of Science and TechnologyShanghai 200237 University of Wisconsin MadisonWisconsin 53706 Wright Laboratory and Department of Physics Yale UniversityNew HavenConnecticut 06520 Brookhaven National Laboratory UptonNew York 11973 Department of Physics National Taiwan UniversityTaipei Institute of High Energy Physics Beijing 100049 National United University Miao-Li Department of Engineering Physics Tsinghua UniversityBejing 100084 Shenzhen University Shenzhen 518060 Sun Yat-Sen(Zhongshan)University Guangzhou North China Electric Power University Bejjing 102206 Chinese University of Hong Kong Hong Kong 999077 Siena College LoudonvilleNew York 12211 Department of Physics and Astronomy University of CaliforniaIrvineCaliformia 92697 University of Science and Technology of China Hefei 230026 Charles University Faculty of Mathematics and PhysicsPrague Department of Physics University of llinois at Urbana-ChampaignUrbanaIlinois 61801 Lawrence Berkeley National Laboratory BerkeleyCalifornia 94720 Department of Physics Illinois Institute of TechnologyChicagoIllinois 60616 joint Institute for Nuclear Research DubnaMoscow Region Beijing Normal University Beijing 100875 Department of Nuclear Science and Technology School of Energy and Power EngineeringXi'an Jiaotong UniversityXi'an 710049 Department of Physics University of HoustonHoustonTexas 77204 China Institute of Atomic Energy Beijing 102413 Shandong University Jinan 250100 Guangxi University Nanning 530004 Center for Neutrino Physics Virginia TechBlacksburgVirginia 24061 Institute of Physics National Chiao-Tung UniversityHsinchu Department of Physics University of CincinnatiCincinnatiOhio 45221 Department of Physies Collge of Science and TechnologyTemple UniversityPhiladelphiaPennsylvania 19122 Dongguan University of Technology Dongguan 523808 Department of Physics University of CaliforniaBerkeleyCalifornia 94720 Department of Physics The University of Hong KongPokfulamHong Kong 999077 School

The establishment of a possible connection between neutrino emission and gravitational-wave(GW)bursts is important to our understanding of the physical processes that occur when black holes or neutron stars *** the Daya Bay experiment,using the data collected from December 2011 to August 2017,a search was per-formed for electron-antineutrino signals that coincided with detected GW events,including GW150914,GW151012,GW151226,GW170104,GW170608,GW 170814,and GW *** used three time windows of±10,±500,and±1000 s relative to the occurrence of the GW events and a neutrino energy range of 1.8 to 100 MeV to search for correlated neutrino *** detected electron-antineutrino candidates were consistent with the expected background rates for all the three time *** monochromatic spectra,we found upper limits(90%confidence level)of the electron-antineutrino fluence of(1.13-2.44)×10^(11)cm^(-2)at 5 MeV to 8.0×10^(7)cm^(-2)at 100 MeV for the three time w *** the assumption of a Fermi-Dirac spectrum,the upper limits were found to be(5.4-7.0)×10^(9)cm^(2)for the three time windows.

关键词： grav itational waves electron-antineutrinos fluence upper limit

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Antineutrino energy spectrum unfolding based on the Daya Bay measurement and its applications

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Chinese Physics C 2021年第7期45卷 1-19页

作者： F.P.An A.B.Balantekin M.Bishai S.Blyth G.F.Cao j.Cao j.F.Chang Y.Chang H.S.Chen S.M.Chen Y.Chen Y.X.Chen j.Cheng Z.K.Cheng j.j.Cherwinka M.C.Chu j.P.Cummings O.Dalager F.S.Deng Y.Y.Ding M.V.Diwan T.Dohnal D.Dolzhikov j.dove M.Dvorak D.A.Dwyer j.P.Gallo M.Gonchar G.H.Gong H.Gong M.Grassi W.Q.Gu j.Y.Guo L.Guo X.H.Guo Y.H.Guo Z.Guo R.W.Hackenburg S.Hans a M.He K.M.Heeger Y.K.Heng Y.K.Hor Y.B.Hsiung B.Z.Hu j.R.Hu T.Hu Z.j.Hu H.X.Huang j.H.Huang X.T.Huang Y.B.Huang P.Huber D.E.jaffe K.L.jen X.L.ji X.P.ji R.A.johnson D.jones L.Kang S.H.Kettel S.Kohn M.Kramer T.j.Langford j.Lee j.H.C.Lee R.T.Lei R.Leitner j.K.C.Leung F.Li H.L.Li j.j.Li Q.j.Li R.H.Li S.Li S.C.Li W.D.Li X.N.Li X.Q.Li Y.F.Li Z.B.Li H.Liang C.j.Lin G.L.Lin S.Lin j.j.Ling j.M.Link26 L.Littenberg B.R.Littlejohn j.C.Liu j.L.Liu j.X.Liu C.Lu H.Q.Lu K.B.Luk B.Z.Ma X.B.Ma X.Y.Ma Y.Q.Ma R.C.Mandujano C.Marshall K.T.McDonald R.D.McKeown Y.Meng j.Napolitano D.Naumov E.Naumova T.M.T.Nguyen j.P.Ochoa-Ricoux A.Olshevskiy H.-R.Pan j.Park S.Patton j.C.Peng C.S.j.Pun F.Z.Qi M.Qi X.Qian N.Raper j.Ren C.Morales Reveco R.Rosero B.Roskovec X.C.Ruan H.Steiner j.L.Sun T.Tmej1 K.Treskov W.-H.Tse C.E.Tull B.Viren V.Vorobel C.H.Wang j.Wang M.Wang N.Y.Wang R.G.Wang W.Wang W.Wang X.Wang Y.Wang Y.F.Wang Z.Wang Z.Wang Z.M.Wang H.Y.Wei L.H.Wei L.j.Wen K.Whisnant C.G.White H.L.H.Wong E.Worcester D.R.Wu F.L.Wu Q.Wu W.j.Wu D.M.Xia Z.Q.Xie Z.Z.Xing H.K.Xu j.L.Xu T.Xu T.Xue C.G.Yang L.Yang Y.Z.Yang H.F.Yao M.Ye M.Yeh B.L.Young H.Z.Yu Z.Y.Yu B.B.Yue V.Zavadskyi S.Zeng Y.Zeng L.Zhan C.Zhang F.Y.Zhang H.H.Zhang j.W.Zhang Q.M.Zhang S.Q.Zhang X.T.Zhang Y.M.Zhang Y.X.Zhang Y.Y.Zhang Z.j.Zhang Z.P.Zhang Z.Y.Zhang j.Zhao R.Z.Zhao L.Zhou H.L.Zhuang j.H.Zou Institute of Modern Physics East China University of Science and TechnologyShanghai 200337 University of Wisconsin MadisonWisconsin 53706 Brookhaven National Laboratory UptonNew York 11973 Department of Physics Nnational Taiwan UniversityTaipei Institute of High Energy Physics Beijing 100049 National United University Miao-Li Department of Engineering Physics Tsinghua UniversityBeijing 100048 Shenzhen University Shenzhen 518061 Sun Yat-Sen(Zhongshan)University Guangzhou 510275 North China Electric Power University Beijing 102206 Chinese University of Hong Kong Hongkong 999077 Siena College LoudonvilleNew York 12211 Department of Physics and Astronomy University of CaliforniaIrvineCalifornia 92697 University of Science and Technology of China Hefei 230022 Charles University Faculty of Mathematics and PhysicsPrague joint Institute for Nuclear Research DubnaMoscow Region Department of Physics University of Illinois at Urbana-ChampaignUrbanaIllinois 61801 Lawrence Berkeley National Laboratory BerkeleyCalifornia 94720 Department of Physics Illinois Institute of TechnologyChicagoIllinois 60616 Beijing Normal University Beijing 100875 Department of Nuclear Science and Technology School of Energy and Power EngineeringXi'an Jiaotong UniversityXi'an 710049 Wright Laboratory and Department of Physics Yale UniversityNew HavenConnecticut 06520 China Institute of Atomic Energy Beijing 102413 Shandong University Jinan 250002 Guangxi University No.100 Daxue East RoadNanning 530004 Center for Neutrino Physics Virginia TechBlacksburgVirginia 24061 Institute of Physics NCTUHsinchu Department of Physics University of CincinnatiCincinnatiOhio 45221 Department of Physics College of Science and TechnologyTemple UniversityPhiladelphiaPennsylvania 19122 Dongguan University of Technology Dongguan 523808 Department of Physics University of CaliforniaBerkeleyCalifornia 94720 Department of Physics The University of Hong KongPokfulamHongkong 999077 School of Physics Nankai UniversityTianjin 300071 Department o

The prediction of reactor antineutrino spectra will play a crucial role as reactor experiments enter the precision *** positron energy spectrum of 3.5 million antineutrino inverse beta decay reactions observed by the Daya Bay experiment,in combination with the fission rates of fissile isotopes in the reactor,is used to extract the positron energy spectra resulting from the fission of specific *** information can be used to produce a precise,data-based prediction of the antineutrino energy spectrum in other reactor antineutrino experiments with different fission fractions than Daya *** positron energy spectra are unfolded to obtain the antineutrino energy spectra by removing the contribution from detector response with the Wiener-SVD unfolding *** results are obtained with other unfolding methods.A technique to construct a data-based prediction of the reactor antineutrino energy spectrum is proposed and *** the reactor fission fractions,the technique can predict the energy spectrum to a 2%*** addition,we illustrate how to perform a rigorous comparison between the unfolded antineutrino spectrum and a theoretical model prediction that avoids the input model bias of the unfolding method.

关键词： reactor antineutrino energy spectrum Daya Bay application

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Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

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Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： Christopher j.O’Connell Matthew j.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA james L.Winkle College of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

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Improved measurement of the reactor antineutrino flux and spectrum at Daya Bay

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Chinese Physics C 2017年第1期41卷 11-46页

作者：安丰鹏 A.B.Balantekin H.R.Band M.Bishai S.Blyth 曹德文曹国富曹俊岑吴镕陳日朗常劲帆張立楚张昀陈和生陈泉佑陈少敏陈义学陈羽程佳樺程捷程雅苹成兆侃 j.j.Cherwinka 朱明中 A.Chukanov j.P.Cummings j.de Arcos 邓子艳丁雪峰丁雅韵 M.V.Diwan M.Dolgareva j.dove D.A.Dwyer W.R.Edwards R.Gill M.Gonchar 龚光华宫辉 M.Grassi 顾文强关梦云郭磊郭如盼郭新恒郭子溢 R.W.Hackenburg 韩然 S.Hans 何苗 K.M.Heeger 衡月昆 A.Higuera Y.K.Hor 熊怡胡貝禎胡涛胡维黄恩泉黄翰雄黄性涛 P.Huber 霍文驹 G.Hussain D.E.jaffe P.jaffke 任國綸 S.jetter 季向盼季筱璐焦健斌 R.A.johnson D.jones j.joshi 康丽 S.H.Kettell S.Kohn M.Kramer 關健强郭文伟郭天能 T.j.Langford K.Lau L.Lebanowski j.Lee 李曉菁雷瑞庭 R.Leitner 李超李登杰李飞李高嵩李秋菊黎山峰 S.C.Li 李卫东李小男李玉峰李志兵梁昊林政儒林贵林林盛鑫林士凱林禹丞凌家杰 j.M.Link L.Littenberg B.R.Littlejohn 刘大为刘江来刘金昌 C.W.Loh 陆昌国路浩奇陆稼书陆锦标吕志鹏马秋梅马晓妍马续波马宇倩 Y.Malyshkin D.A.Martinez Caicedo K.T.McDonald R.D.McKeown I.Mitchell M.Mooney Y.Nakajima j.Napolitano D.Naumov E.Naumova 倪浩然宁哲 j.P.Ochoa-Ricoux A.Olshevskiy 潘孝儒 j.Park S.Patton V.Pec 彭仁杰 L.Pinsky 潘振声齐法制祁鸣钱鑫 N.Raper 任杰 R.Rosero B.Roskovec 阮锡超 H.Steiner 孙功星孙吉良唐炜 D.Taychenachev K.TVeskov K.V.Tsang C.E.Tull N.Viaux B.Viren V.Vorobei 王正祥王萌王乃彦王瑞光王为王玺王贻芳王喆王铮王志民魏瀚宇温良剑 K.Whisnant C.G.White L.Whitehead T.Wise 黄显诺黄振辉 E.Worcester 吳珈豪吴群吴文杰夏冬梅夏经凯邢志忠徐建一徐吉磊徐晔薛涛杨长根杨海波杨雷阳马生杨梦婷叶梅 Z.Ye 叶铭芳杨炳麟于泽源曾珊占亮张超张宏浩张家文张清民张玄同张一鸣张一心张玉美张志坚张智勇张子平赵洁赵庆旺赵豫斌钟玮丽周莉 N.Zhou 庄红林邹佳恒 Institute of Modern Physics East China University of Science and Technology University of Wisconsin Department of Physics Yale University Brookhaven National Laboratory Department of Physics National Taiwan University National United University Nanjing University Institute of High Energy Physics Chinese University of Hong Kong Institute of Physics National Chiao-Tung University Shandong University Department of Engineering Physics Tsinghua University North China Electric Power University Shenzhen University Sun Yat-Sen (Zhongshan) University joint Institute for Nuclear Research Siena College Department of Physics Illinois Institute of Technology Department of Physics University of Illinois at Urbana-Champaign Lawrence Berkeley National Laboratory Department of Physics and Astronomy Shanghai Jiao Tong University Shanghai Laboratory for Particle Physics and Cosmology Beijing Normal University Department of Chemistry and Chemical Technology Bronx Community College Department of Physics University of Houston Center for Neutrino Physics Virginia Tech China Institute of Atomic Energy University of Science and Technology of China School of Physics Nankai University Department of Physics University of Cincinnati Department of Physics College of Science and Technology Temple University Dongguan University of Technology Department of Physics University of California Department of Physics The University of Hong Kong Charles University Faculty of Mathematics and Physics joseph Henry Laboratories Princeton University Department of Nuclear Science and Technology School of Energy and Power Engineering Xi’an Jiaotong University Instituto de F'?sica Pontificia Universidad Católica de Chile California Institute of Technology College of William and Mary Department of Physics Applied Physics and Astronomy Rensselaer Polytechnic Institute China General Nuclear Power Group College of Electronic Science and Engineering National University of Defense Technology Iowa State University Chongqing University

A new measurement of the reactor antineutrino flux and energy spectrum by the Daya Bay reactor neutrino experiment is reported. The antineutrinos were generated by six 2.9 GWth nuclear reactors and detected by eight antineutrino detectors deployed in two near（560 m and 600 m flux-weighted baselines） and one far（1640 m flux-weighted baseline） underground experimental halls. With 621 days of data, more than 1.2 million inverse beta decay（IBD） candidates were detected. The IBD yield in the eight detectors was measured, and the ratio of measured to predicted flux was found to be 0.946±0.020（0.992±0.021） for the Huber＋Mueller（ILL＋Vogel） model. A 2.9σ deviation was found in the measured IBD positron energy spectrum compared to the predictions. In particular, an excess of events in the region of 4–6 MeV was found in the measured spectrum, with a local significance of 4.4σ. A reactor antineutrino spectrum weighted by the IBD cross section is extracted for model-independent predictions.

关键词： antineutrino flux energy spectrum reactor Daya Bay

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Temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries on magnetic resonance imaging

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Neural Regeneration Research 2025年第11期20卷 3144-3150页

作者： Holly Flyger Samantha j.Holdsworth Alistair j.Gunn Laura Bennet Hamid Abbasi Mātai Medical Research Institute Tairāwhiti GisborneNew Zealand Department of Anatomy&Medical Imaging Faculty of Medical and Health SciencesThe University of AucklandAucklandNew Zealand Center for Brain Research The University of AucklandAucklandNew Zealand Auckland Bioengineering Institute The University of AucklandAucklandNew Zealand

Moderate to severe perinatal hypoxic-ischemic encephalopathy occurs in~1 to 3/1000 live births in high-income countries and is associated with a significant risk of death or neurodevelopmental *** assessment is important to help identify highrisk infants,to help families,and to support appropriate interventions.A wide range of monitoring tools is available to assess changes over time,including urine and blood biomarkers,neurological examination,and *** present,magnetic resonance imaging is unique as although it is expensive and not suited to monitoring the early evolution of hypoxic-ischemic encephalopathy by a week of life it can provide direct insight into the anatomical changes in the brain after hypoxic-ischemic encephalopathy and so offers strong prognostic information on the long-term outcome after hypoxic-ischemic *** review investigated the temporal dynamics of neonatal hypoxic-ischemic encephalopathy injuries,with a particular emphasis on exploring the correlation between the prognostic implications of magnetic resonance imaging scans in the first week of life and their relationship to long-term outcome prediction,particularly for infants treated with therapeutic hypothermia.A comprehensive literature search,from 2016 to 2024,identified 20 pertinent *** review highlights that while the optimal timing of magnetic resonance imaging scans is not clear,overall,it suggests that magnetic resonance imaging within the first week of life provides strong prognostic *** challenges limit the timing consistency,particularly the need for intensive care and clinical ***,although most reports examined the prognostic value of scans taken between 4 and 10 days after birth,there is evidence from small numbers of cases that,at times,brain injury may continue to evolve for weeks after *** suggests that in the future it will be important to explore a wider range of times after hypo

关键词： magnetic resonance imaging neonatal hypoxic-ischemic encephalopathy neurodevelopmental outcomes prognostic biomarkers in neuroimaging scan timing therapeutic hypothermia

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Gene therapy for spinal muscular atrophy:perspectives on the possibility of optimizing SMN1 delivery to correct all neurological and systemic perturbations

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Neural Regeneration Research 2025年第7期20卷 2011-2012页

作者： Sharon j.Brown Rafael j.Yáñez-Muñoz Heidi R.Fuller School of Pharmacy and Bioengineering Keele UniversityKeeleUK Wolfson Center for Inherited Neuromuscular Disease TORCH BuildingRJAH Orthopaedic HospitalOswestryUK *** Center of Gene and Cell TherapyDepartment of Biological SciencesSchool of Life Sciences and the EnvironmentRoyal Holloway University of LondonEghamUK

Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and *** genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery that humans have a“back-up”gene,SMN2,which can produce low levels(approximately 10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene *** was traditionally classified according to age of symptom onset and developmental milestones achieved,with life expectancy and severity varying between ***,SMN2 copy number is used as a proxy for the prediction of disease severity,with higher SMN2 copy number typically being associated with reduced severity of SMA,although this relationship is not absolute:some individuals with low SMN2 copy number have less severe SMA phenotypes and vice ***,the etiology of SMA is further complicated by other factors,such as non-typical nucleotide variants and SMN2-independent modifiers of disease severity.

关键词： atrophy traditionally absolute

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Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia S.Rex David j.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National Science Foundation(NSF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

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Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis

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Neural Regeneration Research 2025年第7期20卷 2013-2014页

作者： Nathanael j.Lee Ryota L.Matsuoka Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Molecular Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose and oxygen through its vascular *** vasculature consists of highly divergent blood vessel branches,giving rise to a dense network of capillaries that supply blood to all cells across the *** elaborated vascular network is thought to develop via angiogenesis,a process in which new blood vessels grow from pre-existing *** capillaries exhibit organotypic features distinct from other tissues and are formed primarily by two major endothelial cell(EC)types:those that form the semi-permeable blood-brain barrier(BBB)and those that develop highly permeable pores known as fenestrae(Matsuoka et al.,2022).The structural and functional differences between BBB and fenestrated vascular ECs represent a fundamental feature of brain vasculature and form the foundation for both brain function and homeostasis.

关键词： angiogenesis homeostasis network

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Effect of phytase on phosphorous balance in 20-kg barrows fed low or adequate phosphorous diets

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Animal Nutrition 2020年第1期6卷 9-15页

作者： Tsung Cheng Tsai Robert dove Michael R.Bedford Michael j.Azain Animal&Dairy Science Department University of GeorgiaAthensGA 30602United States AB-VISTA Feed Ingredients MarlboroughWiltsMG SN84ANUnited Kingdom Department of Animal Science University of ArkansasFayettevilleAR 72701United States

The effects of phytase on phosphorus(P)digestibility are well ***,there are few studies that report P balance,particularly when phytase is used in diets that have adequate or deficient *** main objective of the study was to determine the effect of dietary P levels and exogenous phytase on P balance in growing *** first part of the experiment was a 14-d metabolism study conducted with 80 barrows(initial body weight 18.5±0.5 kg)with a 2 x 5 factorial arrangement of treatments and main effects of available P(0.13%available P,low P[Low-P]diet;0.35%available P,adequate P[Adeq-P]diet)and phytase(0,250,500,2,500,and 12,500 U/kg).A portion of the pigs(n=24)fed the Low-P diet,with0,500,2,500,12,500 U/kg phytase,and those fed the Adeq-P diet,with 0 and 12,500 U/kg phytase,remained on test diets for another 4 d,and tissues were collected for determination of bone characteristics and tissue P *** was a P×phytase interaction for P retention that was accounted for by a lack of re sponse to phytase in pigs fed the Adeq-P *** of P was greater with incremental levels of phytase in pigs fed Low-P diets as compared to those fed Adeq-P diets(P level x phytase,P<0.01),but calcium(Ca)retention was greater in pigs fed Adeq-P diets(P level x phytase P<0.01).Apparent total tract digestibility(ATTD)of P was improved by phytase(P<0.001)and was greater in pigs fed Adeq-P diets as compared to those fed Low-P diets(P=0.006).Metatarsal bone ash(quadratic,P=0.01)and strength(linear,P=0.03)was increased by phytase addition to the Low-P *** were no phytase or dietary P effects on P concentrations of the heart,kidney,liver,muscle,and *** results suggest that as compared to the effects in an Adeq-P diet,adding phytase to a Low-P diet was more effective at reducing the P and Ca excretion and restoring average daily gain(ADG).The P released by phytase is absorbed and contributes to improved bone growth,greater rates of tissue accretion,a

关键词： Phosphorous Phytase Bone Calcium Digestibility Tissue

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Constraints on what controls millennial-scale basin-wide denudation across mountain belts,Asia

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Science China Earth Sciences 2025年第1期68卷 74-93页

作者： Ye YANG Steven A.BINNIE Sheng XU Cong-Qiang LIU Tibor j.DUNAI Institute of Surface-Earth System Science School of Earth System ScienceTianjin UniversityTianjin300072China Institute of Geology and Mineralogy University of CologneCologne50674Germany

The terrestrial cosmogenic nuclide dataset consisting of 1233^(10)Be measurements of fluvial sediment samples across the Asian mountain belts is used to constrain the influence of climate,tectonics and topography on Earth-surface denudation processes.^(10)Be-derived basin-wide denudation rates were recalculated using a Monte Carlo simulation approach that relied on pixel-by-pixel production *** rates derived span four orders of magnitude,from 7.4±0.7 mm kyr^(-1)(1σ;Central Tibetan Plateau)to 9,646_(-744)^(+777)mm kyr^(-1)(1σ;Southern Tibetan Plateau),with a median of 186 mm kyr^(-1).Comparing our results with the traditional basin-wide production rate scaling model using a centroid coordinate and mean elevation,suggests that 96.6%of production rates will be underestimated using the latter method,especially for basins with a large *** bias between both methods reaches as large as 40%,caused by basin hypsometry and the nonlinear scaling of production rate with elevation and *** of the correlations between uniformly recalculated denudation rates and tectonics,climate,topography and rock lithology will facilitate the extrapolation of denudation rates in unknown basins using available *** the perspective of local scales,precipitation coupled with neotectonics-driven landslides is likely the most influential factor in subtropical Taiwan Island,while topography primarily constrains surface denudation rates in the eastern Tibetan Plateau within a narrow range of *** highland regions with glacier coverage,such as the Pamir,central and southern Tibetan Plateau high denudation rates are affected by glaciation,whereas lower precipitation and high erosion base level may limit river incision and evolving relief in the Central Tibetan *** contrast to local-scale findings highlighting a dominant factor constraining denudation rate,our large-scale quantitative analyses across the Asian mountain belts finds that(1)topographic

关键词： ^(10)Be-derived denudation rate Climate change Tectonic uplift Topographic gradient Asian mountains

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