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clear lens extraction in angle-closure glaucoma patients

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International journal of Ophthalmology(English edition) 2013年第3期6卷 406-408页

作者： Diego T. Q. barbosa Ashleigh L. Levison Shan c. Lin Department of Ophthalmology University of California

AIM: To describe the results of 5 consecutive cases of clear lens extraction in angle closure patients for the treatment of elevated intraocular pressure (IOP). ·METHODS: Retrospective observational case series. All angle closure patients were on two or more topical glaucoma medications and had prior laser iridotomy. Eyes underwent clear lens extraction by phacoemu - lsification with intraocular lens implantation. ·RESULTS: All five patients in this case series carried the diagnosis of angle -closure glaucoma and had uncontrolled IOP prior to surgery despite topical medications. After clear lens extraction three of the cases had good IOP control (IOP cal medications. In one case the IOP was better controlled after surgery, however, topical medications were required. The desired IOP was not met in one case despite restarting maximum topical therapy. ·cONcLUSION: This case series suggests that there may be a role for therapeutic clear lens extraction in select cases of angle-closure glaucoma.

关键词： clear lens glaucoma cataract angle closure

NEcAB family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno Michael K.E.Schafer Sudena Wang Michael j.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal EF-hand calcium-binding proteins 1–3(NEcAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one EF-hand calcium-binding domain and a functionally less well characterized c-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NEcAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NEcAB2 interacts with predominantly striatal G-protein-coupled receptors, while NEcAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NEcAB proteins exhibit distinct subcellular localizations: NEcAB1 is found in the nucleus and cytosol, NEcAB2 resides in endosomes and the plasma membrane, and NEcAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NEcAB proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NEcAB proteins by controlling the availability of protein–protein interaction domains situated between the EF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium EF hand mitochondria nervous system signal transduction

Recent Achievements in Developing Low Temperature and High Strain Rate Superplastic Materials

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journal of Materials Science & Technology 2001年第1期17卷 19-20页

作者： j.c Huang Inst.Materials Science and Engineering Sun Yat-Son UniversityKaohsiungTaiwan 804China

This paper is to briefly outline our recent activities in developing low temperature or high strain rate superplastic materials, including aircraft-used and general-purpose Al- and Mg-base alloys or composites. as well as Ti3AI base intermetallic alloys. The processing routes applied included the thermomechanical treatment, equal channel angular pressing and other extrusion or forging methods.

关键词： High Strain Rate thermomechanical treatment intermetallic alloys processing routes high strain rate low temperature

Gas Line Pressure Fluctuation Analysis of a Gas-Liquid Reactor

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journal of Thermal Science 2005年第3期14卷 267-271页

作者： j.j.j. cHEN j.c. ZHAO chemical & Materials Engineering Department The University of Auckland Private Bag 92019 Auckland New Zealand ProfessorChemical & Materials Engineering Department The University of Auckland Private Bag 92019 Auckland New Zealand

To ensure efficient operation of metallurgical gas-liquid reactors, the gas bubbles must be uniformly distributed. For high temperature metallurgical reactors, it is impractical and unsafe to carry out visual observations. An air-water model was used to study the relationship between the bubble flow patterns and the pressure fluctuation signals. The fluctuation signals captured in the time domain were transformed into the frequency domain. Various parameters obtained from the transformed data were analysed for their suitability for delineating the bubble flow patterns observed. These parameters and the flow patterns were found to be well-correlated using the gas flow number.

关键词： gas liquid reactors bubble distribution signal analysis

Vibration control of fluid-conveying pipes: a state-of-the-art review

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Applied Mathematics and Mechanics(English Edition) 2023年第9期44卷 1423-1456页

作者： Hu DING j.c.jI Shanghai Key Laboratory of Mechanics in Energy Engineering School of Mechanics and Engineering ScienceShanghai UniversityShanghai 200072China Shaoxing Institute of Technology Shanghai UniversityShaoxing 312074Zhejiang ProvinceChina Shanghai Institute of Aircraft Mechanics and control Shanghai 200092China School of Mechanical and Mechatronic Engineering University of Technology SydneyNew South Wales 2007Australia

Fluid-conveying pipes are widely used to transfer bulk fluids from one point to another in many engineering *** are subject to various excitations from the conveying fluids,the supporting structures,and the working environment,and thus are prone to vibrations such as flow-induced vibrations and acoustic-induced *** can generate variable dynamic stress and large deformation on fluid-conveying pipes,leading to vibration-induced fatigue and damage on the pipes,or even leading to failure of the entire piping system and catastrophic ***,the vibration control of fluid-conveying pipes is essential to ensure the integrity and safety of pipeline systems,and has attracted considerable attention from both researchers and *** present paper aims to provide an extensive review of the state-of-the-art research on the vibration control of fluid-conveying *** vibration analysis of fluid-conveying pipes is briefly discussed to show some key issues involved in the vibration ***,the research progress on the vibration control of fluid-conveying pipes is reviewed from four aspects in terms of passive control,active vibration control,semi-active vibration control,and structural optimization design for vibration ***,the main results of existing research on the vibration control of fluid-conveying pipes are summarized,and future promising research directions are recommended to address the current research *** paper contributes to the understanding of vibration control of fluid-conveying pipes,and will help the research work on the vibration control of fluidconveying pipes attract more attention.

关键词： fuid-conveying pipe vibration passive control nonlinear energy sink(NES) active control semi-active control

Dynamic Mechanical Relaxation in Bulk Metallic Glasses:A Review

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journal of Materials Science & Technology 2014年第6期30卷 523-545页

作者： j.c.Qiao j.M.Pelletier Université de Lyon CNRS France INSA-Lyon MATEIS UMR5510 F-69621 Villeurbanne France

Metallic glasses have aroused considerable interest in the past decades because they exhibit fascinating properties. First, this article briefly outlines the mechanical, thermal properties and application of the metallic glasses. In addition, we focus on the dynamic mechanical relaxation behaviors, i.e. main （α） and secondary （β） relaxations, in metallic glasses. The mechanical relaxation behaviors are connected to the mechanical properties and physical properties in glassy materials. The main relaxation in glassy materials is related to the glass transition phenomenon and viscous flow. On the other hand, the β relaxation is linked to many fundamental issues in metallic glasses. In these materials relaxation processes are directly related to the plastic deformation mechanism. The mechanical relaxations, particularly, the β relaxation provides an excellent opportunity to design metallic glasses with desired physical and mechanical properties. We demonstrate the universal characteristics of main relaxation in metallic glasses. The phenomenological models and the physical theories are introduced to describe the main relaxation in metallic glasses. In parallel, we show the dependence of the α. and β relaxations on the thermal treatments in metallic glasses. Finally, we analyze the correlation between the atomic mobility and the thermo-mechanical treatments in metallic glasses. On the one hand, the atomic mobility in metallic glasses is reduced by physical aging or crystallization. On the other hand, the atomic mobility in metallic glass is enhanced by deformation （i.e. compression and cold rolling）. Importantly, to analyze the atomic mobility in amorphous materials, a physical theory is introduced. This model invokes the concept of quasi-point defects, which correspond to the density fluctuations in the glassy materials.

关键词： Metallic glasses Mechanical properties Main relaxation Secondary relaxation Physical analysis

The Kirkendall effect on erosion resistance of chrome-coated 25cr3Mo2WNiV and 30SiMn2MoV gun barrel steels

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journal of Materials Science & Technology 2024年第10期177卷 246-255页

作者： c.H.Dou P.F.jin c.Z.Wang j.j.Li c.Zhang j.F.Huang c.Zhang Key Laboratory for Advanced Materials Processing State State Key Laboratory for Advanced Metals and MaterialsUniversity of Science and Technology BeijingBeijing 100083China National joint Engineering Research center for Abrasion control and Molding of Metal Materials School of Materials Science and EngineeringHenan University of Science and TechnologyLuoyang 471003China

This study aimed to investigate the erosion behavior and mechanism of a newly developed 25cr3Mo2WNiV steel with a chrome coating using promoted ignition combustion *** erosion threshold pressure and temperature of the chrome-coated 25cr3Mo2WNiV steel were determined to be 0.2 MPa and 254.3 K higher than those of traditional chrome-coated 30SiMn2MoV ***,Kirkendall voids and inter-diffusion between the cr coating and matrix were first observed before *** improved erosion resistance of the chrome-coated 25cr3Mo2WNiV steel was attributed to the suppression of the Kirkendall effect,which minimized heat generation at the cr/matrix interface by pre-venting oxygen diffusion and reducing oxygen affinity.

关键词： Erosion resistance Kirkendall effect cr coating Gun steel

cONTINUUM VOID NUcLEATION MODEL FOR Al-Mg ALLOY SHEET BASED ON MEASURED PARTIcLE DISTRIBUTION

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Acta Mechanica Solida Sinica 2009年第5期22卷 391-398页

作者： c.j.Butcher Department of Mechanical Engineering University of New BrunswickFrederictonNBCanadaE 3B 5A3

Void nucleation within measured particle fields of an aluminum alloy is investigated to develop a continuum nucleation model which reflects nucleation at the individual particle scale. A nucleation model for heterogeneous particle distributions is synchronized with the continuum model of chu and Needleman using the average nucleation strain. The parameters in the continuum model are identified from the particle fields and are evaluated over the range of stress states observed in sheet metal forming. The synchronized continuum nucleation model achieves very good agreement with the nucleation trends for three measured particle fields in uniaxial tension, plane strain, and equal-biaxial tension.

关键词： void nucleation ductile fracture second-phase particles aluminum

Improved spatial decay bounds in the plane Stokes flow

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Applied Mathematics and Mechanics(English Edition) 2009年第7期30卷 833-838页

作者： j.c.SONG Department of Applied Mathematics Hanyang University

This paper investigates spatial decay bounds and a decay rate for the time- dependent Stokes flow of a viscous fluid in a semi-infinite channel. We show how to obtain a near optimal decay rate that is independent of the Reynolds number. We also show that a modification to an analysis given in the literature and a better choice of arbitrary constants yield a decay rate 1.328, which is clearly an improvement compared to 0.91 obtained in the referenced work.

关键词： spatial decay bound differential inequality decay rate