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The effect of Laves phases and nano-precipitates on the electrochemical corrosion resistance of Mg-Al-Ca alloys under alkaline conditions

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journal of Magnesium and Alloys 2024年第6期12卷 2447-2461页

作者： Markus Felten Veronika Chaineux Siyuan Zhang Ali Tehranchi Tilmann Hickel Christina Scheu joshua Spille Marta Lipińska-Chwałek joachim Mayer Benjamin Berkels Marcus Hans Imke Greving Silja Flenner Sandra Sefa Daniela zander Chair of Corrosion and Corrosion Protection RWTH Aachen UniversityAachen 52072 Germany Max-Planck-Institut für Eisenforschung GmbH Düsseldorf 40237 Germany Central Facility for Electron Microscopy RWTH Aachen UniversityAachen 52074 Germany Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons Forschungszentrum Jülich GmbHJülich 52428Germany Mathematical Image and Signal Processing Aachen Institute for Advanced Study in Computational Engineering ScienceRWTH Aachen UniversityAachen 52062 Germany Materials Chemistry RWTH Aachen UniversityAachen 52074 Germany Institute of Materials Physics Helmholtz-Zentrum HereonGeesthacht 21502 Germany

The electrochemical corrosion mechanisms of Mg alloys were extensively studied in previous investigations of different chemical com-positions,modified surface states and various electrolyte ***,recent research focused on the active state of Mg dissolution,leading to unresolved effects of secondary phases adjacent to a stableα-solid solution passive *** present study investigates the fundamental electrochemical corrosion mechanisms of three different Laves phases with varying phase morphologies and phase fractions in the passive state of Mg-Al-Ca *** microstructure was characterized by(transmission-)electron microscopy and synchrotron-based transmission X-ray *** electrochemical corrosion resistance was determined with a standard three-electrode setup and advanced in-situ flow cell measurements.A new electrochemical activity sequence(C15>C36>α-Mg>C14)was obtained,as a result of a stable passive layer formation on theα-solid ***,nm-scale Mg-rich precipitates were identified within the Laves phases,which tend to inhibit the corrosion kinetics.

关键词： Laves phase STEM Magnesium Corrosion Passive layer

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首次除颤由急诊医生还是由急救员执行?

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德国医学 1995年第1期12卷 3-3页

作者： D.Mauer T.Schneider Ph.Diehl W.Dick F.Brehmer R.juchems D.Kettler R.Kleine-zander H.Klingler R.Rossi H.j.Roth j.Schüttler D.Stratmann U.Strohmenger j.zander 郝连杰 Klinik für Anasthesiologie Johannes Gutenberg-UniversitatMainz 同济医科大学附属同济医院

除颤是心室颤动唯一的病因治疗,除颤越早,病人存活的机率就越大。为缩短病人院外复苏心脏停止至首次除颤之间的间期,在美国和其他无院外急救医疗系统的国家,将除颤权授于受过相应培训的急救站人员,在医生的监督下执行。在德国柏林和慕... 详细信息

除颤是心室颤动唯一的病因治疗,除颤越早,病人存活的机率就越大。为缩短病人院外复苏心脏停止至首次除颤之间的间期,在美国和其他无院外急救医疗系统的国家,将除颤权授于受过相应培训的急救站人员,在医生的监督下执行。在德国柏林和慕尼黑已进行了急救站人员首先除颤的规范化,并已有成果报导。但尚无急救站人员除颤与目前常规治疗制度(除颤由急救医生执行)相比较的前瞻性研究。

关键词：心室颤动除颤术急症处理医生

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Effect of coronary artery dynamics on the wall shear stress vector field topological skeleton in fluid–structure interaction analyses

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International journal of Mechanical System Dynamics 2023年第1期3卷 48-57页

作者： Harry j.Carpenter Mergen H.Ghayesh Anthony C.zander Peter j.Psaltis School of Electrical and Mechanical Engineering University of AdelaideAdelaideSouth AustraliaAustralia Vascular Research Centre Lifelong Health ThemeSouth Australian Health and Medical Research Institute(SAHMRI)AdelaideSouth AustraliaAustralia Adelaide Medical School University of AdelaideAdelaideSouth AustraliaAustralia Department of Cardiology Central Adelaide Local Health NetworkAdelaideSouth AustraliaAustralia

In this paper,we investigate the impact of coronary artery dynamics on the wall shear stress(WSS)vector field topology by comparing fluid–structure interaction(FSI)and computational fluid dynamics(CFD)*** one of the most common causes of death globally,coronary artery disease(CAD)is a significant economic burden;however,novel approaches are still needed to improve our ability to predict its *** can include the unique dynamical factors present in the coronary *** investigate the impact of these dynamical factors,we study an idealized artery model with sequential *** transient simulations made use of the hyperelastic artery and lipid constitutive equations,non‐Newtonian blood viscosity,and the characteristic out‐of‐phase pressure and velocity distribution of the left anterior descending coronary *** compare changes to established metrics of time‐averaged WSS(TAWSS)and the oscillatory shear index(OSI)to changes in the emerging WSS divergence,calculated here in a modified version to handle the deforming mesh of FSI *** suggest that the motion of the artery can impact downstream patterns in both divergence and *** magnitude is also decreased by up to 57%due to motion in some *** divergence patterns varied most significantly between simulations over the systolic period,the time of the largest *** investigation highlights that coronary dynamics could impact markers of potential CAD progression and warrants further detailed investigations in more diverse geometries and patient cases.

关键词： computational fluid dynamics divergence fluid–structure interaction topology wall shear stress

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Artificial intelligence for characterization of diminutive colorectal polyps:A feasibility study comparing two computer-aided diagnosis systems

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Artificial Intelligence in Gastrointestinal Endoscopy 2024年第1期5卷 11-22页

作者： Quirine Eunice Wennie van der zander Ramon M Schreuder Ayla Thijssen Carolus H j Kusters Nikoo Dehghani Thom Scheeve Bjorn Winkens Mirjam C M van der Ende-van Loon Peter H N de With Fons van der Sommen Ad A M Masclee Erik j Schoon Department of Gastroenterology and Hepatology Maastricht University Medical CenterMaastricht 6202 AZNetherlands GROW School for Oncology and ReproductionMaastricht UniversityMaastricht 6200 MDNetherlands Division of Gastroenterology and Hepatology Catharina Hospital EindhovenEindhoven 5602 ZANetherlands Department of Electrical Engineering Eindhoven University of TechnologyEindhoven 5600 MBNetherlands Department of Methodology and Statistics Maastricht UniversityPostbus 6166200 MD MaastrichtNetherlands School for Public Health and Primary Care Maastricht UniversityMaastricht 6200 MDNetherlands

BACKGROUND Artificial intelligence(AI)has potential in the optical diagnosis of colorectal *** To evaluate the feasibility of the real-time use of the computer-aided diagnosis system(CADx)AI for ColoRectal Polyps(AI4CRP)for the optical diagnosis of diminutive colorectal polyps and to compare the performance with CAD EYE^(TM)(Fujifilm,Tokyo,japan).CADx influence on the optical diagnosis of an expert endoscopist was also *** AI4CRP was developed in-house and CAD EYE was proprietary software provided by *** CADxsystems exploit convolutional neural *** polyps were characterized as benign or premalignant and histopathology was used as gold ***4CRP provided an objective assessment of its characterization by presenting a calibrated confidence characterization value(range 0.0-1.0).A predefined cut-off value of 0.6 was set with values0.76).Self-critical AI4CRP’s diagnostic performances excluded low confidence *** AI4CRP use was feasible and performed on 30 patients with 51 colorectal ***-critical AI4CRP,excluding 14 low confidence characterizations[27.5%(14/51)],had a diagnostic accuracy of 89.2%,sensitivity of 89.7%,and specificity of 87.5%,which was higher compared to *** EYE had a 83.7%diagnostic accuracy,74.2%sensitivity,and 100.0%*** performances of the endoscopist alone(before AI)increased nonsignificantly after reviewing the CADx characterizations of both AI4CRP and CAD EYE(AI-assisted endoscopist).Diagnostic performances of the AI-assisted endoscopist were higher compared to both CADx-systems,except for specificity for which CAD EYE performed *** Real-time use of AI4CRP was *** confidence values provided by a CADx is novel and self-critical AI4CRP sho

关键词： Artificial intelligence Colorectal polyp characterization Computer aided diagnosis Diminutive colorectal polyps Optical diagnosis Self-critical artificial intelligence

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治疗后牙的X线形态

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放射学实践 1986年第4期3卷 161-163页

作者： Von H.Vogel A.zander j.Blumel j.Blurger 陈王善继苏州医学院

X线检查能显示牙根治疗的质量,在牙根管填充不全或填充过度的情况下常产生牙根尖的牙周炎.对合不良的填充及凸出的牙冠缘常使邻近颌骨骨质破坏.全口性断层牙片对各牙的细微分析常嫌不够,须辅以个别牙的局部点片. 本文阐明,X线检查可发... 详细信息

X线检查能显示牙根治疗的质量,在牙根管填充不全或填充过度的情况下常产生牙根尖的牙周炎.对合不良的填充及凸出的牙冠缘常使邻近颌骨骨质破坏.全口性断层牙片对各牙的细微分析常嫌不够,须辅以个别牙的局部点片. 本文阐明,X线检查可发现经治疗后牙的典型形态学变化,变化的发生率及何种变化具有病变的性质.从而以鉴别是治疗中的技术问题,还是基础疾病的复发或晚期并发症.

关键词：牙根尖透亮区根管填充后牙牙冠局部点片游离端骨质破坏牙片

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用马利兰、环磷酰胺、足叶乙甙为预处理方案对急性髓系白血病患者异基因骨髓移植治疗第一次完全缓解时的高剂量化疗

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德国医学 2000年第1期17卷 4-6页

作者： A.R.zander C.Berger N.Krger M.Stockschlder W.Krǜger M.Horstmann j.Grimm W.Zeller Hkabisch R.Erttmann P.Schnrock R.Kuse D.Braumann H.j.Illiger W.Fiedler M.deWitt K.D.Hossfeld H.j.Weh 祁明芳 Bone Marrow Transplantaion Unit Universittskrankenhaus EppendorfD-20246 Hamburg Germany 广州暨南大学医学院第一附属医院

大剂量化疗和全身放疗(TBI)后,组织相合的同胞造血干细胞移植已用于急、慢性白血病的治疗。它对第一次完全缓解(CR1)的急性髓系白血病(AML)患者,长期无病生存率可达50%,而对复发的急性白血病患者,长期无病生存率约为10%～20%。异基因骨... 详细信息

大剂量化疗和全身放疗(TBI)后,组织相合的同胞造血干细胞移植已用于急、慢性白血病的治疗。它对第一次完全缓解(CR1)的急性髓系白血病(AML)患者,长期无病生存率可达50%,而对复发的急性白血病患者,长期无病生存率约为10%～20%。异基因骨髓移植(allo-BMT)预处理方案有 TBI+化疗和单用化疗两种。

关键词：急性白血病骨髓移植马利兰环磷酰胺

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发生在直系亲属的2例成人型卵巢粒层细胞肿瘤

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世界核心医学期刊文摘（妇产科学分册） 2006年第1期2卷 48-48页

作者： Stevens T. A. Brown j. zander D. S. 杨晓梅(译) 马超(校) j. Brown Department of Gynecologic Oncology University of Texas M. D. Anderson Cancer Center 1155 Herman Pressler Houston TX 77030 United States 不详

Background. Known inherited mutations are responsible for approximately 10% of all epithelial ovarian cancers; however, prior to this report, sex cord-stromal ovarian tumors had not been documented in related females. Case. We report here on a mother and daughter, each diagnosed with rare, adult-type granulosa cell tumors of the ovary. Conclusion. This novel report of granulosa cell tumors occurring in two first-degree relatives must be examined with reserve. No familial tendency has previously been documented, and our finding may be coincidental. However, if additional cases are reported and future research is undertaken, biological markers and inherited mutations for certain sex cord-stromal ovarian tumors may be identified. These advances could lead to targeted therapy and specific surveillance protocols with appropriate surgical interventions for high-risk patients.

关键词：卵巢粒层细胞肿瘤直系亲属成人型卵巢性索间质肿瘤生物学标志物遗传突变卵巢上皮癌家族倾向性病例报道外科技术

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经皮腔内血管成形术与Turbostatic涂碳支架在膝下动脉应用中的比较:InPeria Ⅱ期试验

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国际医学放射学杂志 2012年第1期 79-79页

作者： T.Rand j.Lammer C.Rabbia M.Maynar T.zander T.jahnke 孟小茜 Department of Radiology General Hospital HietzingWolkersbergenstr.11130 ViennaAustria

目的比较经皮球囊扩张术与支架植入在治疗严重的下肢缺血重度病变中的临床效果和成功率。材料与方法本试验为伦理委员会批准的随机前瞻性研究。对88例严重下肢缺血病人的131个病变行经皮球囊扩张术或支架植入

关键词：支架植入术下肢缺血病变球囊扩张术管腔直径 InPeria Turbostatic 经皮

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